What is baby panadol. The drug "Panadol" for children (syrup): instructions for use, indications and contraindications

Inflammation is a kind of protective reaction of the body to various pathogens (bacteria, viruses, chemical compounds). At the same time, special substances are released into the blood in the body, waste products poison the body of the child. For pain relief, elimination of unpleasant symptoms, a non-steroidal agent is used - Panadol Baby syrup.

The drug effectively copes with the baby's fever, relieves the pain that accompanies almost every cold. Children's Panadol is very popular with parents, in most cases they speak of the drug on the positive side.

Pharmacological properties

Panadol for children belongs to the group of non-steroidal anti-inflammatory, antiseptic agents. The active ingredient is paracetamol, the substance is able to block inflammatory mediators that provoke the inflammatory process, fever, and other unpleasant symptoms of a cold.

A distinctive feature of the drug is a small anti-inflammatory activity of the component, after all, when a substance enters the bloodstream, it begins to break down under the action of enzymes of cell membranes. The drug has a loyal effect on the children's body, in rare cases it causes side effects. According to the instructions, the maximum concentration of Panadol Baby is reached after half an hour, so the medicine acts quickly, greatly alleviating the baby's condition.

The destruction of the elements of the drug occurs in the liver, then the active component of the syrup is excreted with the kidneys. If the dosage is observed, the drug does not disturb the electrolyte balance, water retention does not occur, the work of the gastrointestinal tract remains normal.

Composition and form of release

Panadol Baby is produced in the form of a syrup for oral administration. The bottle contains 100 ml of medication, a convenient dispenser facilitates the process of taking the medication. The liquid has a pinkish color, a characteristic viscous consistency and a pleasant strawberry aroma. The manufacturer produces the product in the form of pills, powder, solution for infusion, rectal suppositories. For children, a suspension is most often used. Pleasant taste, ease of use have earned the love of many children and their parents.

The main component of Panadol for children is paracetamol. The substance was first synthesized in the United States back in 1887. For quite a long period of time it was tested, studied, some scientists doubted its effectiveness. Mass production of paracetamol began only in 1953, the substance is very popular today.

Paracetamol was originally used as a pain reliever for various degrees of pain. In addition, the substance was actively used to solve problems with the gastrointestinal tract in children.

Note! During the research, it was found that Panadol acts effectively, copes well with headaches, toothaches, fever, and alleviates the course of colds. It is not allowed to exceed the dosage, due to the high risk of side effects if the recommendations described in the instructions are not followed.

Indications for use

Children's Panadol is used in the following cases:

• to lower the baby's body temperature, to alleviate the unpleasant symptoms of colds (flu, and others);
• relief, including when;
• elimination of pain in otitis media, sinusitis, tonsillitis,;
• sometimes used to alleviate the condition with various neuralgic problems (only with the permission of the doctor);
• in some cases, they are used once for children 2-3 months after vaccination. The instructions indicate that the drug copes with discomfort, reduces the risk of side effects after vaccination.

Panadol is approved for children from three months to twelve years of age. Before using the drug, consult a pediatrician, strictly follow his instructions.

Contraindications

Children's Panadol is forbidden to be taken in the following cases:

• the presence of hypersensitivity to paracetamol or other components of the drug;
• blood diseases;
• children's age up to three months (can be taken only with the permission of a pediatrician);
• serious violations of the functioning of the liver;
• kidney pathology;
• It is not recommended to combine with taking other drugs containing paracetamol.

Before use, be sure to carefully read the instructions, follow the helpful instructions.

Possible side effects

Exceeding the dosage, individual intolerance to the components of the drug leads to a number of unpleasant consequences.

Improper functioning of the gastrointestinal tract:

• loss of appetite;
• bouts of nausea,;
• loss of appetite, sluggish state of the crumbs;
• severe pain in the intestines or stomach;
• excessive constant excess of the dosage leads to necrosis of liver cells, as a result - liver failure.

Problems with the nervous system:

• in some cases, there is increased activity of the baby, insomnia, excessive anxiety;
• a one-time intake of a large amount of Panadol leads to dizziness, severe pain in the temples, and sometimes loss of consciousness.

Immune system response (allergic reactions):

• swelling of the respiratory tract, Quincke's edema;
• rash on the body, redness in the area of ​​formations;
• the most serious complication is Steven-Jones syndrome (it is a medicinal tissue necrosis). Sometimes there is Lyell's syndrome (lesion of epidermal tissues). Pathological conditions require immediate medical intervention, urgent resuscitation.

Damage to the hematopoietic organs:

• in children, there is pallor of the skin of the face, cyanosis of the nasolabial triangle, sometimes pains are felt in the region of the heart;
• thrombocytopenia is noted, which is accompanied by excessive bleeding, poor blood clotting;
• prolonged, uncontrolled use of the drug leads to disturbances in the work of the bone marrow.

From the endocrine system:

• glycemic coma;
• lowering blood sugar levels.

Sometimes kidney failure develops, problems with urination.

Instructions for use and dosage

Panadol syrup for children is taken orally, be sure to stir the suspension in the vial before use. Using a measuring syringe, draw the required amount of funds, pour into the baby's mouth. After use, rinse the device.

Approximate scheme of application and dosage of Panadol:

• 2–3 months- individual dosage is prescribed exclusively by the attending physician;
• 3–6 months- give the crumbs 4 ml, the maximum allowable dose daily is 16 ml;
• from 6 months to 1 year- 5 ml up to four times a day;
• one to two years- 7 ml, up to 28 ml per day;
• one to two years– 9 ml, it is allowed to use up to 36 ml per day;
• three to six years old- 10 ml, the maximum allowed to give crumbs is 40 ml;
• six to nine years old- 14 ml, you can give the baby 56 ml per day;
• nine to twelve years old- 20 ml, daily intake of 80 ml can be allowed.

Anyway the specific dosage prescribed by the attending physician, It is undesirable to give the child the drug on its own.

Interaction with other drugs

Panadol for children It is not recommended to combine with other anti-inflammatory, antipyretic medicinal products. Even when combined with multivitamin products, notify the doctor. The child's body is very sensitive, acutely reacts to the intake of several drugs at the same time.

5 ml suspensions contain 120 mg paracetamol and additional components: maltitol, xanthan gum, sodium nipasept, water, azorubine, strawberry flavor, malic acid, and citric acid.

Rectal suppositories, Panadol suppositories for children- each suppository contains 125 mg paracetamol . Solid fats act as auxiliary components.

Release form

Suspension , panadol syrup

It has a pink color and a strawberry smell. The syrup is viscous in consistency and contains crystals. Packed in bottles of 100 or 300 ml. In addition to the bottle, the cardboard pack contains instructions and a special measuring syringe.

Candles

Homogeneous consistency of white color, cone-shaped, in appearance suppositories have a greasy sheen, do not contain impurities and various physical defects. Candles are packed in strips of 5 or 10 pieces.

pharmachologic effect

Antipyretic analgesic . The mechanism of action is based on blocking the enzyme cyclooxygenases in the central part of the nervous system. Due to the ability to influence the centers of thermoregulation and pain, antipyretic and analgesic action . Panadol for children does not have an anti-inflammatory effect. The active substance does not affect the processes of synthesis in peripherally located tissues, does not affect the water-salt and does not irritate the mucous membranes of the digestive tract.

Pharmacodynamics and pharmacokinetics

suction, distribution

Paracetamol has high absorption. The active substance is almost completely and quickly absorbed from the lumen of the digestive tract. After 30-60 minutes, the maximum concentration of the active substance is recorded in the blood. Paracetamol binds to plasma proteins only by 15%. In body fluids, the active ingredient is distributed evenly.

Metabolism

As a result of metabolism in the hepatic system, several active metabolites are formed. The main metabolite in newborns and in children 3-10 years old is paracetamol sulfate , and in children older than 12 years, the main metabolite is conjugated glucuronide .

About 17% of the drug undergoes hydroxylation with the formation of active metabolites. The main metabolic products are conjugated with the participation of glutathione, with a lack of which Panadol metabolites begin to block the enzyme systems of hepatocyte liver cells, causing.

breeding

During the first day, 90-100% of the accepted therapeutic dose is excreted in the urine. The half-life is 2-3 hours. Metabolites are excreted after undergoing a conjugation process in the hepatic system. About 3% of the drug is excreted unchanged.

Indications for use

Panadol for children is prescribed for children from 3 months of age to 12 years of age:

• pain syndrome during teething;
• sore throat;
• ear pain with;
• decrease in elevated body temperature with infectious lesions, colds, , , , , and etc.

For children aged 2-3 months, a single dose of antipyretic medication is allowed after vaccination.

Contraindications

• neonatal period;
• severe pathology of the renal system or liver;
• individual hypersensitivity.

Relative contraindications:

• severe pathology of the circulatory system ( leukopenia , anemia , thrombocytopenia );
• genetically inherent absence of the enzyme glucose-6-phosphate dehydrogenase;
• pathology of the renal system;
• Gilbert's syndrome and other diseases of the liver system.

It is unacceptable to take other medicines at the same time, one of the components of which is paracetamol.

Side effects

• epigastric pain;
• vomit;
• skin rashes;
• nausea;
• thrombocytopenia ;
• skin itching;
• leukopenia ;
• anemia .

Taking the dosages recommended by the manufacturer allows you to avoid negative symptoms. When registering other adverse reactions not described in the instructions, immediate discontinuation of therapy and seeking medical help from an appropriate specialist is required.

Children's Panadol, Instructions for use (Method and dosage)

Syrup Children's Panadol, instructions for use

Shake the bottle thoroughly before use. Correct and rational dosing is ensured by a special measuring syringe included in the package.

Suspension instructions for children:

From 3 months: 3-4 times a day, 15 mg / kg of body weight. No more than 60 mg / kg can be prescribed per day. It is permissible to take syrup for children every 4-6 hours, but not more than 4 times a day (at the recommended dose of 15 mg / kg). The dosage is selected individually, taking into account the concomitant pathology, the tolerance of the drug, the age of the child.

In order to reduce body temperature, Panadol for children can be taken no longer than 3 days; for pain relief - 5 days. In the absence of the expected effect, a pediatrician's consultation is required.

Instructions for candles Panadol for children

Suppositories are intended for rectal administration (dosage of paracetamol 125 mg). Candles for children are administered every 4-6 hours, 1 suppository (for children from 3 months to 3 years). Candles can be used no more than 3 times a day.

Overdose

Acute poisoning is manifested by vomiting, increased epigastric pain, nausea, pallor of the skin. 1-2 days after poisoning, the first signs of toxic damage to the hepatic system appear (increased levels of ALT and AST, pain in the liver). In extremely severe cases, failure of the liver system, coma, develops.

With chronic overdose, toxic lesions of the kidneys and liver gradually develop:

• interstitial nephritis ;
• nonspecific bacteriuria ;
• papillary necrosis ;

Therapy of departure is aimed at the early withdrawal of the drug and the implementation of measures to detoxification (gastric lavage, administration of enterosorbent drugs). It can act as a specific antidote.

Interaction

Long-term use of Paracetamol enhances the anticoagulant effect of derivatives

Analgesic and antipyretic.
Pharmacodynamics. The analgesic and antipyretic effect of paracetamol is due to the inhibition of prostaglandin synthesis and the predominant effect on the thermoregulatory center in the hypothalamus.
Pharmacokinetics. Paracetamol is well absorbed from the gastrointestinal tract. Peak plasma concentration occurs 15-60 minutes after ingestion. It is metabolized in the liver to form glucuronide and paracetamol sulfate. It is excreted mainly by the kidneys. The half-life is 1-4 hours.

Indications for the use of the drug Panadol baby

pain syndrome of low and medium intensity of various origins in children, fever in infectious and inflammatory diseases (including childhood viral infections), post-vaccination hyperthermia in children aged 2-3 months.

How to use Panadol baby

The drug is intended for the treatment of children and only for oral administration. The measuring device is inside the package. The dose of paracetamol for children is calculated depending on age and body weight. A single dose of paracetamol is 15 mg / kg of body weight, daily - 60 mg / kg of body weight.
Dosing Panadol Baby
For children aged 2-3 months: for the symptomatic treatment of reactions to vaccination, a single dose of 2.5 ml of suspension is used. If necessary, the dose can be repeated, but not earlier than after 4 hours. If the child's body temperature does not decrease after a second dose, you should consult a doctor. Further use of the drug in children of this age to facilitate reactions to vaccination, as well as use in children under 3 months for other indications, is possible only under medical supervision. If it is necessary to use the drug in a premature baby under the age of 3 months, the drug can be used only on the advice of a doctor.
Children aged 3 months to 12 years. In the table, find the dose that corresponds to the weight of the child. If the child's weight is not known, find the dose in the table that corresponds to the child's age.
Dosing table for paracetamol suspension 120 mg/5 ml in children:

The frequency of administration is up to 4 times a day with an interval between doses of at least 4 hours.
Do not use more than 4 doses within 24 hours.
The maximum daily dose of paracetamol is 60 mg/kg of body weight. The course of treatment is 3-5 days.
For convenient dosing of the suspension, the measuring device has marks from 0.5 to 8 ml. If you need to measure a dose of more than 8 ml, you should first measure the first 8 ml of the suspension, and then the remainder of the dose.

Contraindications to the use of the drug Panadol baby

Hypersensitivity to any component of the drug, severe violations of the liver and / or kidneys, age up to 2 months.

Side effects of Panadol baby

Rarely - allergic reactions, agranulocytosis, thrombocytopenia, anemia, aseptic pyuria.

Special instructions for the use of the drug Panadol baby

Premature babies under the age of 3 months can only be used on the advice of a doctor. Do not prescribe the drug simultaneously with other drugs containing paracetamol. If the severity of the symptoms of the disease does not decrease or the patient's condition worsens within 3 days of treatment with the drug, you should consult a doctor.

Panadol baby interactions

The rate of absorption of paracetamol may increase with concomitant use of metoclopramide and domperidone and decrease with concomitant use of cholesteramine. Paracetamol may enhance the anticoagulant effect of warfarin and other coumarins. Barbiturates reduce the antipyretic effect of paracetamol.

Storage conditions for Panadol baby

At temperatures up to 25 °C. Do not freeze. The shelf life of the vial after opening is 1 month.

List of pharmacies where you can buy Panadol baby:

• St. Petersburg

Panadol is a drug that is prescribed for colds. It lowers body temperature and relieves pain associated with general intoxication of the body. Liquid dosage form allows you to prescribe the drug from the first months of life of babies. The article discusses detailed instructions for the use of Panadol children's syrup.

The chemical composition of the drug

The active substance of the drug is paracetamol. It is a non-narcotic analgesic (relieves pain) and an antipyretic (antipyretic). It has a weak anti-inflammatory effect.

The mechanism of action is based on the blocking of cyclooxygenase - enzymes that are involved in the production of biologically active substances of prostaglandins. These enzymes increase the sensitivity of pain mediators - bradykinin and histamine. By stopping this process, paracetamol prevents the spread of inflammation and reduces sensitivity. The effect of the substance on the centers of thermoregulation and pain occurs in the central parts of the nervous system.

Additional components:

• xantham gum - suspension stabilizers;
• sorbitol - filler and structurant;
• nipasept sodium - solvent;
• azorubine is a synthetic dye;
• maltitol is a sugar substitute;
• citric acid - preservative;
• strawberry flavor;
• purified water.

The composition of the suspension does not include ethyl alcohol, sugar and aspirin, which can cause acute liver failure in children.

Medicinal properties of syrup

The main properties of Panadol are antipyretic and analgesic. When ingested, the drug does not have a negative effect on the gastrointestinal mucosa, does not violate the water and electrolyte metabolism in the body.

The syrup is quickly and completely absorbed in the intestine. No more than 15% of the active substance binds to plasma proteins. The maximum accumulation in the blood is achieved after 0.5-1 hour. Paracetamol is distributed evenly in internal fluids and soft tissues.

The substance breaks down in the liver into metabolites. In children, some of these breakdown products can cause the death of hepatocytes (liver cells).

Paracetamol (more than 90%) is excreted in the urine during the day. In an unchanged form, the chemical compound leaves the body in an amount of 3% of the total dose.

Indications for prescribing syrup for children

Panadol syrup in pediatrics is prescribed for acute respiratory infections, which are accompanied by fever. The medicine also relieves pain of various origins.

Indications for appointment:

• fever with SARS and influenza;
• muscle pain and bone ache associated with high intoxication of the body and hyperthermia;
• headache;
• childhood infections - mumps, measles, whooping cough, chicken pox.

Panadol is prescribed for babies for pain during teething of milk teeth, especially when the process is accompanied by a rise in body temperature to high levels, more than 38.5 ° C.

The syrup is indicated for otitis media, which is a complication of colds, rhinitis, sinusitis and is often diagnosed in preschool children.

The drug eliminates severe soreness in the throat with tonsillitis, pharyngitis, laryngitis.

Panadol is prescribed as a prevention of fever (hyperthermia) after vaccination in babies of the first year of life.

Release form and therapeutic regimens

Children's Panadol is available as a syrup for oral administration.. In appearance, it is a pink viscous suspension with the presence of crystals and the smell of strawberries.

5 ml of liquid contains 120 mg of the active substance.

The drug goes on sale in dark glass bottles of 100 and 300 ml. One carton box contains 1 bottle, a measuring syringe and a guide to using the medicine. Store at room temperature not exceeding 30°C.

The syrup is taken orally. Shake the suspension thoroughly before taking it. To accurately dose the medicine, use a syringe with a graduation.

The dose is calculated based on the body weight of the child. The maximum daily amount of the drug for infants from 3 years old is 60 mg / 1 kg of weight. This volume is divided into 3-4 doses and given to the child at regular intervals.

Dose calculation table for children depending on age

In order to reduce the temperature during a cold, the suspension is taken no more than 3 days. To eliminate muscle, tooth or ear pain, drink the syrup for 5 days.

For the prevention of post-vaccination hyperthermia, the child is given 2.5 ml of syrup once.

The time interval between doses is 4 hours.

If the condition does not improve during treatment with Panadol, you should consult a doctor for advice.

Panadol is prescribed with caution to infants born prematurely, small children whose body weight does not correspond to their age.

Features of the use of syrup

Panadol should be used with caution in young patients with a history of functional liver and kidney disease..

Do not use more than 4 doses per day. It is impossible to give a suspension to a baby on your own, without a doctor's prescription.

If the child has sugar intolerance, then it is better to stop taking the medicine, as it contains sorbitol and maltitol. The dyes and flavorings included in the composition can cause allergic reactions, including those of a delayed type.

It is forbidden to use Panadol with other drugs that are based on paracetamol.

Side effects

Most often, when treating with a suspension in children, local allergic manifestations are noted:

• skin hypersensitivity;
• itching, irritation, epidermis;
• generalized rash (all over the body);
• skin erythema (specific rashes);
• hives.

Sometimes there is angioedema, anaphylaxis. Extremely rarely, epidermal toxic necrolysis (severe allergic bullous dermatitis) can develop.

Side effects from the internal organs and systems:

• Gastrointestinal tract - nausea, discomfort in the epigastric region, diarrhea, impaired liver function;
• respiratory organs - increased sensitivity of the respiratory mucosa to nonsteroidal anti-inflammatory drugs, bronchospasm;
• endocrine glands - a drop in blood sugar, up to a hypoglycemic coma;
• hematopoietic organs - a decrease in the number of platelets, a decrease in the level of leukocytes and resistance to bacterial infection, a violation of the hemoglobin formula, resulting in shortness of breath, skin cyanosis, anemia, diffuse hemorrhages under the skin, bleeding;
• aseptic pyuria - a large number of leukocytes in the urine without the content of pathogenic microorganisms.

Syrup overdose

With an overdose of Panadol, the risk of severe liver damage increases dramatically.. This is possible if the child has taken a dose of more than 150 mg / kg. The category of young patients with a history of such pathologies falls into the risk group for the manifestation of symptoms:

• chronic starvation;
• cachexia - extreme wasting as a result of severe weight loss;
• cystic fibrosis - a hereditary disease with severe respiratory disorders;
• immunodeficiency states - HIV, AIDS;
• children taking drugs that increase the enzymatic function of the liver - Phenobarbital, Rifampicin, Carbamazepine, Primidone.

Distinctive signs of an overdose the first day after taking:

• pale skin, loss of strength, decreased physical activity;
• loss of appetite, nausea, vomiting;
• pain in the stomach, colic in the intestines.

In a severe form of Panadol poisoning, acute renal failure develops. Against its background, such dangerous conditions can develop:

• encephalopathy - the destruction of nerve cells as a result of oxygen starvation or circulatory disorders;
• hemorrhages;
• coma.

In acute renal failure, tubular necrosis occurs. This is manifested by severe pain in the lower back, the presence of blood and proteins in the urine. Cases of heart rhythm failures and inflammation of the pancreas were recorded.

Long-term treatment in a child disrupts the coordination of movement, the baby becomes excited and irritable.

Contraindications for the appointment of syrup

The drug is not prescribed for hypersensitivity to paracetamol and other auxiliary components.

Contraindications for the appointment of Panadol:

• children's age up to 2 months;
• hereditary fructose intolerance;
• blood diseases associated with a violation of the quantitative or qualitative composition;
• functional diseases of the liver.

Panadol in the form of a syrup for children, subject to the treatment regimens and rules of admission, effectively relieves pain and temperature of various etiologies. The drug is relatively safe for young children in the first year of life, so it is often used in pediatric practice.

Instruction

Panadol syrup helps to get rid of a fever in a child, relieve pain and inflammation caused by colds. Most parents respond positively to this medicine.

Compound

The analgesic is sold in the form of an oral suspension with a pleasant strawberry flavor. 5 ml of the product contains 120 mg of paracetamol, which is the active ingredient of the drug. Additional composition:

• maltitol;
• xanthan gum;
• malic acid;
• sodium nipasept;
• strawberry flavor;
• water;
• azorubine;
• citric acid;
• sorbitol.

The suspension is placed in dark glass bottles of 100 or 300 ml. The medication comes with instructions and a measuring syringe.

Pharmacological group

Antipyretics-analgesics (anilides).

Mechanism of action

Pharmacodynamics

Antipyretic analgesic has antipyretic and analgesic effects. Suppresses the activity of cyclooxygenase in the central nervous system, affecting the center of temperature regulation and pain.

It has almost no anti-inflammatory effect. The drug does not affect the mucous membranes of the esophagus and the water-salt balance, as it does not change the production of prostaglandins.

Pharmacokinetics

The drug has a high degree of absorption. Absorption of paracetamol is made from the digestive tract. Its highest plasma level is observed after 30-60 minutes.

The level of communication with plasma proteins reaches 15%. It is evenly distributed in biofluids.

Metabolism of paracetamol occurs in the liver structures.

The half-life is 2 to 3 hours. The drug is excreted along with the urine.

Indications for use

Panadol baby syrup is prescribed for children from 3 months to 12 years old in such cases:

• to reduce fever against the background of colds and infectious pathologies (measles, mumps, scarlet fever, chicken pox, rubella, Michigan flu);
• for the prevention of rickets;
• to eliminate toothache, ear and headache, as well as discomfort in the throat.

In patients 2-3 months of age, a single application of the suspension may be prescribed to reduce the temperature after vaccination.

Contraindications

Suspension is not indicated in the following situations:

• with individual sensitivity to paracetamol and other elements of the syrup;
• newborn children (due to the risk of pathologies of physical development);
• severe pathologies of the kidneys and liver.

The medicine is carefully prescribed for severe forms of blood diseases, moderate disorders of the kidneys and liver.

The drug must not be used in combination with other drugs that contain paracetamol.

How to take panadol syrup?

How to calculate the dose?

Doses are calculated taking into account the weight and age of the child. For babies 2-3 months old, the medicine is prescribed with caution and under the supervision of a specialist. Approximate dosages for children (by weight):

• 3-6 months, 6-8 kg: single - from 96 mg, daily - 384 mg;
• 6-12 months and weighing 8-10 kg: single dose - from 120 mg, limit - 480 mg;
• from 1 year to 2 years and weighing 10-13 kg: single - 168 mg, maximum - 672 mg;
• 2-3 years old and weighing 13-15 kg: single dose - 216 mg, not more than 864 mg per day;
• from 3 to 6 years old with a weight of 15-21 kg: single - 240 mg, limit - 960 mg;
• 6-9 years old with a weight of 21-29 kg: single - 336 mg, maximum - 1344 mg;
• from 9 to 12 years old with a weight of 29-42 kg: one-time - 480, not more than 1920 mg per day.

Before or after a meal?

It is advisable to take the medication before meals. In this case, its level of absorption will be optimal.

How long does the syrup take to work?

The syrup begins to act within 30-60 minutes after oral administration.

Time of action

The effect of the medicine lasts up to 4-5 hours.

How to give to a child?

Children's syrup is taken orally. Before use, the vial with the medication should be shaken thoroughly. Dosages are recommended to be selected using a measuring syringe.

Side effects from taking panadol syrup

A child may experience skin rashes, angioedema, urticaria, vomiting, discomfort in the peritoneum, anemia, leukopenia, and cardiac arrhythmias during the use of the syrup.

In this case, the medication should be stopped and seek help from a medical specialist.

Overdose

Signs of paracetamol poisoning: abdominal pain, nausea and vomiting, pale skin, excessive sweating. After 1-2 days, lesions of the hepatic structures may develop. In severe situations, liver failure, coma and encephalopathy are observed.

In chronic overdose, nephrotoxic and hepatotoxic manifestations (interstitial nephritis, bacteriuria, renal colic, papillary necrosis) may occur.

The child is shown bowel lavage and the use of Polyphepan or activated charcoal (enterosorbents). Acetylcysteine ​​is an effective antidote to paracetamol.

Features of the use of panadol syrup

The doctor should be informed about taking the syrup when prescribing tests to detect the concentration of glucose and uric acid in the blood serum.

Abdominal pain is one of the symptoms of paracetamol poisoning.

When using the drug for a course longer than 7 days, it is desirable to control the composition of peripheral blood and liver function.

Is it possible to syrup during pregnancy and lactation?

Syrup (suspension) is used in pediatrics. Pregnant and lactating women can take the drug only on prescription.

For impaired renal function

The syrup is prescribed with caution for moderate disorders. In severe cases, it is forbidden to take it.

Influence on concentration

The syrup does not violate psychomotor.

drug interaction

With other drugs

With the simultaneous use of an analgesic with anticonvulsants, Difenin, barbiturates, Butadione and Rifampicin, the likelihood of a hepatotoxic effect increases.

In combination with Chloramphenicol, its toxicity increases.

The anticoagulant activity of warfarin and other coumarin derivatives increases with prolonged use of paracetamol, which can cause bleeding.

Alcohol compatibility

It is forbidden to combine the drug with alcohol-containing drugs and drinks.

Terms and conditions of storage

Do not freeze syrup. It is suitable for storage in a place protected from the sun and moisture, at temperatures up to +30°C. The shelf life of the syrup is 36 months.

Terms of dispensing from pharmacies

Are they sold without a prescription?

The syrup belongs to over-the-counter medicines.

What is the price?

From 87 rub. for a 100 ml bottle.

Analogues

• candles Panadol;
• Paracetamol (syrup, tablets and suppositories for rectal administration);
• Efferalgan (rectal suppositories and syrup);
• Cefekon.