Candles Kipferon for children - what the doctor ordered. Kipferon suppositories - instructions for use and indications for the drug Candles for intestinal infection for children

Kipferon: instructions for use and reviews

Latin name: Kipferon

ATX code: G02CC; L03AX

Active substance: interferon alpha (Interferon Alfa), normal human immunoglobulin (Human Normal Immunoglobulin)

Producer: Alfarm, OOO (Russia)

Description and photo update: 26.08.2019

Means that stimulate the processes of immunity.

Composition Kipferon

1 suppository contains:

• interferon human recombinant alpha-2 not less than 500,000 M,
• complex immunoglobulin preparation (CIP) 60 mg.

KIP is a lyophilized protein solution containing immunoglobulins (lg) of classes G, M, A in the following ratio:

• lgG - 50% -70,
• lgM - 15% -25,
• lgA - 15% -25%.

Manufacturers

Alpharm (Russia)

pharmachologic effect

Kipferon® has a pronounced antiviral, antibacterial and antichlamydial activity, exhibits immunomodulatory and anti-inflammatory properties.

The complex composition and method of application of the drug cause a number of therapeutic effects:

• the local and general resistance of the body increases,
• elimination of the pathogen occurs and protection mechanisms are activated at the sites of penetration of pathogens,
• manifestations of viral and microbial intoxication are reduced,
• with erosion of the cervix, stimulation of reparative processes in its tissues is provided.

Kipferon® prevents the deepening of the disturbed balance of autoflora (dysbiosis) and the excessive growth of opportunistic microorganisms in diseases.

Side effects of Kipferon

No data.

Indications for use

Treatment of acute respiratory diseases, inflammatory diseases of the oropharynx of bacterial and viral etiology, acute viral (rotavirus) and bacterial (salmonellosis, dysentery, coli infection) intestinal infections, intestinal dysbacteriosis of various origins in children and adults; treatment of urogenital chlamydia in women, including those with manifestations of vaginal dysbacteriosis, vulvovaginitis, cervical cervicitis, cervical erosion.

The use of the drug is carried out against the background of generally accepted specific therapy.

Contraindications Kipferon

Hypersensitivity.

Method of application and dosage

For acute respiratory diseases, inflammatory diseases of the oropharynx of bacterial and viral etiology, for viral (rotavirus) and bacterial (salmonellosis, dysentery, coli infection) intestinal infections in children, intestinal dysbacteriosis of various origins, suppositories are prescribed based on the content of recombinant alpha-2-interferon 500,000 IU and 60 mg TIP per suppository.

The daily dose is 1-3 suppositories, depending on the age of the patient:

• in the first year - rectally 1 suppository per day (in 1 dose,
• from 1 year to 3 years - 1 suppository 2 times a day,
• after 3 years - 1 suppository 3 times a day for 5-7 days.

In patients with tonsillitis with a pronounced purulent process, the course of treatment should be extended to 7-8 days.

Suppositories are used rectally without specific therapy or simultaneously with it.

In the treatment of urogenital chlamydia in women, suppositories are administered deeply intravaginally (before contact with the posterior fornix of the vagina and cervix) 1-2, depending on the severity of the disease, 2 times a day.

The course of treatment averages 10 days; in the presence of erosion of the cervix, the use of the drug is continued until its epithelialization.

According to the indications, the course of treatment can be repeated.

Treatment should begin in the first days after the end of menstruation.

Kipferon belongs to the drugs that affect the child's immune system and help the body overcome its diseases. It belongs to the group of long-acting immunoglobulators. The medicine is developed and produced in Russia.

It is widely used in the complex therapy of infections of various origins in both adults and children. Although Kipferon suppositories are not a purely children's drug, many pediatricians prefer him over other drugs with a similar effect.

The use of Kipferon suppositories helps to strengthen the child's immunity, since the children's system of protection against diseases is imperfect and is just beginning to take shape.

In our article, we suggest that you familiarize yourself with the detailed instructions for using Kipferon candles for children, with parent reviews and average prices for a children's drug.

Release form and composition

Kipferon is produced in the form of suppositories (suppositories). For children, they are used only by introduction into the rectum. The drug is produced in packs of 5 and 10 pieces. Candles are white or beige with a yellowish tint, made in the form of a cylinder with a sharp end.

The form of the medicine in the form of candles - very convenient solution for small children who are difficult to get to take drugs in the form of syrups or tablets.

The composition of the drug includes two main active substances: the immunoglobulin complex and interferon 2-alpha. As part of a complex immunoglobulin, there are antibodies that successfully repel the attacks of bacteria and viruses.

The action of the second substance has an antiviral, antibacterial and anti-inflammatory effect. Kipferon also has an antichlamydial medicinal effect.

As auxiliary ingredients, the composition of suppositories includes paraffin, emulsifier and fat. They contribute to the uniform distribution of the two main substances in the blood and cells.

Many mothers are frightened by talk that allegedly donated blood is part of the product. This is not true. Kipferon contains highly purified plasma protein. Cases of infection with such drugs due to blood components have not been recorded.

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Indications for admission

The list of diseases for which doctors prescribe Kipferon antiviral suppositories for children is quite large. These candles are used for:

• viral hepatitis A, B, C;
• inflammatory diseases of the respiratory tract, such as bronchitis, pneumonia, (in combination with antibiotics);
• genital herpes;
• (dysentery, salmonellosis);
• chlamydial infections that have arisen in newborns as a result of infection from the mother during childbirth;
• frequent colds;
• dysbiosis of the gastrointestinal tract;
• papillomas and condylomas on the body.

Suppositories can be prescribed to children of any age, even infants.

Contraindications

The drug has practically no contraindications for use.



The only exception is individual intolerance to the components of the drug.

Side effects of the drug have not been identified.

You can often find the opinion that Kipferon is contraindicated for allergy sufferers, since it contains protein.

In reality allergic reactions can cause any drug even the most common one.

Kipferon belongs to low-allergenic drugs, negative reactions to it rarely occur.

The safety of the drug has led to its widespread use in pediatrics.

How it works, dosage

In the treatment of various infections, the following results can be obtained:

• elimination of symptoms of intoxication;
• disappearance of wheezing in the lungs;
• decrease in body temperature;
• normalization of the number of lymphocytes in the blood;
• improvement of immunity;
• reducing the risk of spreading viruses in the body.

For inflammatory diseases of the respiratory tract, 2 suppositories are needed per day (in the morning and evening hours) for 5 days. With herpes, the norm is 1 suppository per day for 10 days.



When prescribing the drug, body weight is also taken into account. Up to 12 years, the dose should not exceed more than 2 suppositories per day, for adolescents - no more than 4.

Of great importance is the use of funds in the first three days of the disease. The duration of treatment depends on the severity of the course of the disease.

Accurate the dosage is determined by the doctor.

It is possible to use the drug as a prophylactic. It is usually prescribed if the baby is often sick with colds. Preventive course of admission - 2 weeks, to enhance the action, you can take 2-3 courses.

To avoid bacterial complications after surgery, Kipferon is prescribed during the period of preparation for surgery.

Before the introduction of a candle, the rectum must be cleaned. The child is given an enema, and then the anus is washed with warm water and soap. After a deep injection into the anus, you need to lie on your side for at least 15 minutes so that the medicine is well absorbed in the body.

Interaction with other medicinal substances

The drug can be combined with other drugs. It is often prescribed along with antibacterial drugs. The therapeutic effect of both groups of drugs is enhanced.

Kipferon has a pronounced antiviral, antibacterial and antichlamydial activity, exhibits immunomodulatory and anti-inflammatory properties. The complex composition and method of using the drug cause a number of therapeutic effects: local and general resistance of the body increases, the pathogen is eliminated and defense mechanisms are activated at the sites of penetration of pathogens, the manifestations of viral and microbial intoxication are reduced, with erosion of the cervix, stimulation of reparative processes in its tissues is provided. Kipferon® prevents the deepening of the disturbed balance of autoflora (dysbiosis) and the excessive growth of opportunistic microorganisms in diseases.

Indications for use of the drug Kipferon

Urogenital chlamydia in women, incl. against the background of vaginal dysbacteriosis, vulvovaginitis, cervical cervicitis, cervical erosion (in combination with conventional antibiotic therapy.

Contraindications to the use of the drug Kipferon

Hypersensitivity to the components contained in the suppository.

The use of the drug Kipferon

Rectally, intravaginally (before contact with the posterior vaginal fornix and cervix). 1-2 supp. (depending on the severity of the disease), 2 times a day. The course of treatment is, on average, 10 days; in the presence of erosion of the cervix, the use is continued until its epithelialization. According to the indications, the course of treatment can be repeated. Treatment should begin in the first days after the end of menstruation. Before administration, it is recommended to remove mucus from the mucous membranes of the vagina and cervix.
Schemes of prescribing the drug Kipferon®, suppositories
Chlamydial infections
Children - 1 supp. 1 time per day for 10 days. In girls with erased clinical forms of chlamydial vulvovaginitis and without clinical manifestations of the inflammatory process of the uterus and its appendages, chlamydial infection of the urinary tract, respiratory chlamydia, treatment is carried out only against the background of vaginal and oral administration of eubiotics, in other cases, treatment of chlamydia in children with Kipferon® is combined with the appointment of antibiotics and eubiotics.
Adults - in a daily dose of 1-2 million IU (2-4 supp.) in 2 doses, the course of treatment is 10-14 days; additionally, antibiotic therapy is carried out and eubiotics are prescribed vaginally and orally. If clinical signs of chlamydia or infection with chlamydia persist after treatment, a second course of therapy with Kipferon® is carried out.
With viral hepatitis B, C and A in children
Rectally. For children under 7 years of age, Kipferon® is prescribed in a single dose of 50,000 IU / kg of body weight in 2 doses, but not more than 1 million IU / day (2 supp.); 8-11 years - 1.5 million IU / day (3 supp.); older than 12 years - 2 million IU / day (4 supp.). The duration of the course of treatment for acute viral hepatitis is 14 days. The first 7 days the drug is used daily, then - 2 times a week. With a protracted course of the disease, the duration of the course reaches 3-4 weeks.
With frequent inflammatory diseases of the respiratory tract, recurrent bronchitis (including with obstructive syndrome), pneumonia in children
Rectally. In a daily dose of 1 million IU (2 supp.) in 2 doses daily for the first 5 days, then 2 times a week for 3 weeks. Perhaps the use in the form of monotherapy or in complex treatment, against the background of basic antibiotic therapy.
With genital herpes
Adults: 1-2 million IU (2-4 supp.) for 10-14 days; it is possible to conduct a second course of treatment; children - in a daily dose of 500,000 IU (1 supp.) in 1 dose, the course of treatment is 10 days.
Antibiotic therapy for genital herpes is carried out only in the presence of a concomitant bacterial infection. In women and adolescent girls, it is recommended to start treatment with the drug in the first days after the end of menstruation. Before vaginal administration, it is advisable to remove mucus with a swab from the mucous membranes of the vagina and cervix.
For intestinal infections in children
Rectally (after a cleansing enema or defecation). Children under 12 years old - in an average single dose of 50,000 IU / kg of body weight, but not more than 1 million IU / day (2 supp.), Over 12 years old - no more than 2 million IU (4 supp.). It is most expedient to use the drug in the first 3 days of the disease, i. during the acute period. The course of treatment of moderate viral diarrhea is 3-5 days; severe form - 7 days.
Kipferon® may be the only etiopathogenetic treatment (without antibacterial drugs) against the background of generally accepted basic therapy (oral rehydration, dosed therapeutic nutrition, if necessary, infusion therapy). In severe forms, it is advisable to include antibiotics in the complex of therapy.
In preparation for planned gynecological and other operations in order to prevent infectious complications
Rectally. Kipferon® is used in a daily dose of 1 million IU (2 supp.), in 2 doses, 3-5 days before and during surgery, as well as in the postoperative period. The course of treatment is 10-15 days. The interval between doses is 12 hours.

Side effects of the drug Kipferon

The drug is considered low-allergenic, however, the content of a large amount of protein in the candles can cause an allergic reaction in children.

Interactions of the drug Kipferon

No data.

List of pharmacies where you can buy Kipferon:

• St. Petersburg

Instructions for use

Kipferon instructions for use

Dosage form

Suppositories are white, white with a yellowish tinge or light beige in color, with a characteristic odor, cylindrical in shape with a pointed end, uniform on a longitudinal section. An air rod or a funnel-shaped recess is allowed on the cut. Color heterogeneity in the form of marbling is allowed.

Compound

Composition per suppository:

Active ingredients:

Immunoglobulin complex preparation (CIP) 200 mg

Interferon alpha-2b (interferon alpha-2b human, recombinant) 500000 ME

Excipients:

Special purpose fat "SolPro" confectionery for chocolate products and sweets - 838 mg

Petroleum solid paraffin P-2 - 85 mg

Emulsifier "Solid" (T-2) - 85 mg

Sodium hydrogen phosphate dodecahydrate - 0.055 mg

Sodium dihydrophosphate dihydrate - 0.018 mg

Sodium chloride - 0.110 mg

Purified water - 12 mg

Pharmacodynamics

Pharmachologic effect.

Immunomodulatory;

Antiviral;

Antichlamydial.

pharmacological properties.

Suppositories "Kipferon®" is a complex dosage form containing human recombinant interferon-β2 and a complex immunoglobulin preparation (CIP). Interferon-?2 is an activator of innate and acquired immunity, has a pronounced antiviral activity, enhances protection against viral, chlamydial, mycoplasmal and bacterial infections, has an immunomodulatory effect in the development of immunological reactions, promotes the growth and preservation of the intestinal and vaginal normal flora. The biological activity of interferon-?2 is realized through interaction with the receptor apparatus of immunocompetent and other cells, leading to an increase in the expression of HLA I and HLA II molecules on the surface of all cell types and the regulation of cell cooperation, an increase in the activity of natural killers, as well as giving intact cells resistance against them. cytolytic action, proliferation of CD8 T cells. Increases the production of interferon gamma by natural killers. The complex immunoglobulin preparation of CIP contains specific and non-specific immunoglobulins of classes G, M, A. The combination of antiviral, antichlamydial, antibacterial and antitoxic antibodies belonging to different classes of immunoglobulins provides agglutination, neutralization and precipitation of etiotropic pathogenic agents. At the site of application, it provides stabilization of interferon from mucous membrane secretions, normalizes local immunity due to the intake of IgA and IgM with suppositories (substitution effect), increases the activity of locally formed cytokines.

Side effects

Not registered.

Selling Features

Released without a prescription

Special conditions

Precautionary measures.

Indications

The drug is used in the complex therapy of diseases accompanied by secondary immunodeficiency states:

Acute respiratory diseases, inflammatory diseases of the oropharynx of bacterial and viral etiology in children and adults;

Acute viral (rotavirus) and bacterial (salmonellosis, dysentery, coli infection) intestinal infections, including those with manifestations of intestinal dysbacteriosis of varying severity in children;

Urogenital chlamydia in women (including pregnant women in the II-III trimesters of pregnancy), including those with manifestations of vaginal dysbacteriosis, vulvovaginitis, uterine cervicitis, cervical erosion.

Contraindications

Individual intolerance to individual components, pregnancy I trimester, lactation.

drug interaction

There were no negative effects on other drugs.

Prices for Kipferon in other cities

Mode of application

Dosage

Acute respiratory diseases, inflammatory diseases of the oropharynx of bacterial and viral etiology: suppositories are administered rectally (mainly after defecation) for children under 1 year old, one suppository per day, children under 12 years old - 1 suppository twice a day, adults and children over 12 years old - 1 suppository three times a day. The most effective and appropriate is the appointment of "Kipferon®" in the acute period of the disease (preferably in the first 3 days). The duration of the course of treatment is determined by the etiology, severity of the disease, the presence of concomitant complications, pathological conditions and is 5-7 days.

Acute viral (rotavirus) and bacterial (salmonellosis, dysentery, coli infection) intestinal infections, including those with manifestations of intestinal dysbacteriosis of varying severity in children: suppositories are administered rectally (mainly after defecation) for children under 1 year old, one suppository per day, children under 12 years old - 1 suppository twice a day, adults and children over 12 years old - 1 suppository three times a day. It is most effective and expedient to prescribe the drug in the acute period of the disease (preferably in the first 3 days). The duration of the course of treatment is determined by the etiology, severity of the disease, the presence of concomitant complications, pathological conditions and is 5-7 days.

Urogenital chlamydia in women (including pregnant women in the II-III trimesters of pregnancy), including those with manifestations of vaginal dysbacteriosis, vulvovaginitis, uterine cervicitis, cervical erosion: suppositories are administered deeply intravaginally (before contact with the posterior vaginal fornix and cervix) 1-2 suppositories, depending on the severity of the disease, twice a day. The course of treatment averages 10 days; in the presence of erosion of the cervix, the use of the drug is continued until its epithelialization. According to the indications, the course of treatment can be repeated after one month. Treatment should begin in the first days after the end of menstruation. Before administration, it is recommended to remove mucus from the mucous membranes of the vagina and cervix.