Vitamin B6 - instructions, use, indications, dosage. Why is an overdose of vitamin B6 dangerous and what are the symptoms

If the intestines work correctly, then vitamin B6 is synthesized by the microflora in sufficient quantities. However, due to the impact of negative factors, such as antibiotic therapy, smoking, alcohol abuse, beneficial microorganisms are destroyed. Then it is required to fill the resulting deficit with external sources.

Vitamin B6 preparations in tablets

The names of the main manufacturers of vitamin complexes that contain pyridoxine:

• Supradin;
• Vitrum;
• Elevit Pronatal;
• Berocco;
• Doppelhertz.

Prices range from 500 rubles to two thousand. Consumer reviews vary, it is better to choose on the recommendation of a doctor. This group of preparations with vitamins B6 is not medicines, but dietary supplements. They can be bought at the pharmacy without a prescription. Doctors urge not to prescribe dietary supplements on your own, so that there is no overdose: a surplus of vitamins is no less dangerous than their lack.

Instructions for use

Injection vitamin B6 is administered in 100 ml or 200 ml, depending on the disease. With pyridoxine-dependent convulsive syndrome, adults are prescribed 30-600 ml once a day, and children - 10-100 ml.

In tablet form, a capsule per day is enough for a month. The daily requirement of an adult for pyridoxine is 2.5 mg, a child - from 0.3 to 1.6 mg, a pregnant woman - up to 4.6 mg. In an effort to lose weight or fearing a deficiency, some exceed the allowable values, and then an excess of vitamin B6 occurs in the body.

Overdose syndromes:

• anemia;
• dizziness;
• violations of coordination;
• fainting.

Natural sources of vitamin B6 instead of pills

Doctors came to an unequivocal conclusion: if a person has a varied, nutritious diet, without diets and all kinds of restrictions, then most of the necessary nutrients and elements of the body are obtained from food. Deficiency is not formed, and, therefore, the use of pharmacological preparations is not required.

Foods high in vitamin B6:

• yeast;
• liver of animals and cod;
• pork;
• germinated wheat;
• bran;
• unrefined grain;
• potato;
• bananas;
• carrot;
• syrup;
• beans;
• cabbage;
• raw chicken yolk;
• sea ​​fish.

pharmachologic effect

All vitamins are designated by letters and have their own chemical name. Compounds are divided into water-soluble and fat-soluble. B6 vitamins are crystals that dissolve well in water. They come in three varieties: priridoxine hydrochloride, pyridoxamine, and pyridoxal. In medicine, they are often referred to by the name pyridoxine.

Vitamin B6 in the human body helps to absorb many substances and elements: unsaturated fatty acids, calcium, so that the muscles function normally.

In addition, pyridoxine:

• plays an important role in metabolism, as it transports compounds through cell membranes;
• strengthens the immune system (increases the level of T-lymphocytes);
• lowers xanthurenic acid and blood glucose levels (prevention of diabetes mellitus);
• important for women: normalizes estrogen levels;
• increases the production of serotonin and norepinephrine. A sufficient level of these substances provides a person with a normal emotional state;

in combination with magnesium, it prevents the formation of oxalates, which form stones and sand in the kidneys.

Mode of application

The solution for injection is injected into a vein, into the muscles or under the skin (this method is rarely used). The purpose of treatment and the specifics of the disease determine the use of pyridoxine. Most often, to undergo one course of treatment, it is enough to pierce 25 injections. During the year, repetition of therapy is permissible.

Tablets are more suitable for preventive purposes to strengthen the body, improve the condition of hair, skin and nails. In this form, a combination with B1 is permissible, but it is not recommended to inject these substances at the same time.

In dermatology, ointments or creams with vitamin B6 are used at a concentration of 10 mg or 50 mg per 100 g of the product.

If you violate the instructions for taking, an overdose may occur, so you should not exceed the doses prescribed by the doctor and change the injection schedule.

Release form

Available as a solution for injection in ampoules or in the form of tablets. For external use, it is recommended to use ointments.

Indications

• women taking hormonal contraceptive pills;
• those who drink steroids;
• people who are overweight and want to lose weight;
• for problematic oily skin prone to acne. In this case, it is enough to use external means, for example, ointment. Gradually, the rashes stop;
• with osteochondrosis, so that the muscles are strong;
• in the treatment of neurological diseases;
• reduces the harmful effects of toxic drugs on the liver;
• used in the treatment of skin ailments: psoriasis, herpes zoster, exudative diathesis, dermatitis;
• with sideroblastic anemia;
• with various forms of hepatitis;
• hair loss.

Pregnancy is also an indication for taking B6 vitamins, since during this period there is an active production of the hormone estrogen. By the end of the child's gestation period, the need for pyridoxine increases tenfold.

Contraindications

• intolerance;
• ulcers of the stomach and duodenum;
• ischemic disease;
• liver failure;
• severe liver damage;
• it has been proven that pyridoxine is not compatible with B1.

Side effects

1. Allergy. When it manifests itself, the drug should be stopped immediately.
2. Feelings of pressure in the limbs, numbness. In another way, this condition is called "stocking syndrome".
3. Convulsions are possible, but they are rare and only occur at times of rapid administration of the drug.
4. A lactating woman may experience a drop in lactation levels. In certain cases, a similar effect is used for medicinal purposes.

Greetings, my inquisitive readers. Today we have a special guest with you - this is the “vitamin of life”. Yes, yes, you heard right. Without this element, the origin of life, its development and flow is unthinkable. What is this miracle cure? It is pyridoxine or vitamin B6.

I learned about the magical properties of this element when my son was 1 month old. And we planned to go to see a neurologist.

The fact is that during childbirth there was hypoxia. The first month for my husband and I was a real hell. Antoshka often shouted, slept very badly. I fell asleep and woke up 20 minutes later. They walked like zombies. I just wanted to sleep.

We were advised a good neurologist, and we went to see him. He examined the baby with such care. He asked about his son - about sleep, how he eats and so on. It turned out that there is a tremor and the neck mows to the left.

And then he prescribed glycine (a common amino acid) + magnesium B6 for half a tablet. Found that it is still sold in liquid form in ampoules. So we decided to give them to Antokha. After 4 days began to observe changes in behavior. Sonny after eating began to sleep for an hour, became more calm. A week later, he began to sleep through the night without waking up to eat. He wakes up on his own, examines toys, can play alone. And how he floundered in the water - he filled the whole bath.

And what impressed me was the effect of this miracle remedy. After the cancellation, the action continued anyway. I myself write and knock on wood so as not to jinx it. And then I brag to you 🙂

fell asleep while I was collecting it for a walk 🙂

Seeing such a magical effect of the vitamin on my son, I decided to find out more about B6. It turns out that this element is simply priceless - absolutely everyone needs it.

Why does the body need vitamin B6?

Pyridoxine belongs to the B vitamin family. These compounds play an important role in a number of physical and psychological functions. They are known to help maintain a healthy metabolism and the functioning of the nervous system. And such elements are also important for the health of the skin and eyes, the normal functioning of the liver.

Pyridoxine has several derivatives, including pyridoxal phosphate, pyridoxal-5-phosphate, and pyridoxamine. These important substances are involved in various biological functions of the body.

Vitamin b6 is involved in the following processes:

• supports the nervous system
• helps produce hemoglobin, which carries oxygen in red blood cells (erythrocytes) throughout the body
• balances blood sugar levels;
• helps to get energy from the food we eat;
• improves mood;
• creates antibodies that the immune system uses to protect us;
• important for hair - strengthens them and accelerates growth.

Deficiency symptoms

B6 deficiency is extremely rare in Western countries. Most people get enough calories and vitamins from food every day. Some experts even believe that some consume too high levels of pyridoxine altogether. Therefore, its excess is an even more common problem among the population than its deficiency.

With such an amount of an element, the body can easily replenish from its diet. But if you are over 50, then the dosage of b6 should be increased to 2.2 mg per day. Otherwise, the body will begin to experience a shortage.

As I said, friends, the deficiency of this vitamin is not very common. However, this problem still exists. The following symptoms help to judge the lack of element B6:

• mood changes (irritability, anxiety and depression);
• lethargy;
• muscle pain;
• chronic fatigue;
• exacerbation of PMS symptoms;
• worsening symptoms of anemia;
• insomnia;
• convulsions;
• dermatitis and yellow-lemon shade of the skin;
• deterioration of the cardiovascular system.

Most often, vitamin B6 deficiency is associated with neuropsychiatric disorders. Recent studies have shown that deficiency of this element is usually common among older people. They are at greater risk of developing Alzheimer's and other forms of dementia as B6 levels decrease.

Where is contained

This element is found in many foods that we eat. These are nuts and seeds, some types of meat and poultry, avocados, legumes.

Banana is the leader in pyridoxine content among fruits and vegetables. But there is one caveat - this is true only for those countries where it is grown. In our area, the championship is occupied by potatoes. However, in order to save b6 in it to the maximum extent, it must be properly prepared.

High levels of the vitamin are found in the following foods (at a daily intake of 2 mg for adults):

However, remember that heat treatment of food products reduces the content of this miracle element in them. For example, bread baked from white flour contains only 20% of vitamins. This is in comparison with the amount that was in wheat grains. And when boiling potatoes (if you drain the water in which vegetables were cooked), 93% of pyridoxine is lost.

Conservation also does not allow saving b6 in full. During this processing, the product loses from 57% to 77% of the vitamin. Yes, and freezing has a detrimental effect on him.

Instructions for use

For kids:

For adults:

Vitamin B6 is water soluble, which means it will be excreted from the body in the urine. For this reason, as a rule, there is no particular concern in connection with an overdose. But you should not abuse this element either, because it can cause an undesirable reaction of the body.

I emphasize once again that pyridoxine is water-soluble. This means that the body is not able to store this element for future needs. Therefore, you should regularly eat foods rich in B6.

Indications for the use of an additional vitamin complex:

• anemia;
• seasickness;
• toxicosis in pregnant women;
• hepatitis;
• leukopenia;
• autism;
• dermatitis, psoriasis and other skin diseases;
• diseases of the nervous system, etc.

If you are going to buy pyridoxine supplements from a pharmacy, be sure to get a high quality product. Pyridoxine hydrochloride is sold in tablets and ampoules.

Just don't self-medicate. Everything can end up with the fact that later you will “solve the puzzle” - what is this happening to the body. And then you will definitely have to go to the doctor so that he can heal you. Agree, the price of such an experiment is too high.

Benefits of Vitamin B6

1. Supports vascular health. Pyridoxine is needed to regulate blood levels of a substance called homocysteine. It is a type of amino acid obtained from protein foods. Its high rates are associated with the development of diseases of the heart and blood vessels. Without enough vitamin B6, homocysteine ​​builds up in the body and damages blood vessels. As a result, it can provoke a heart attack or stroke. Recent studies have shown that this vitamin works best with folic acid. When patients take this "duet", the total concentration of homocysteine ​​is significantly reduced ( 2 ).
   
   
2. Supports brain function. Vitamin helps its proper development and functioning. Studies have shown that b6 deficiency can affect memory function and contribute to the development of cognitive impairment (Alzheimer's disease and age-related dementia) ( 3 ). Also, this element plays an important role in the creation of serotonin and norepinephrine. Known as “happiness hormones,” these two hormones help control mood, energy, and focus. Researchers believe that certain behavioral disorders in children are caused by low levels of serotonin. Thus, taking vitamin B6 may have a beneficial effect on children ( 4 ).
3. Improves mood. Some prescription antidepressants contain vitamin B6. It has a significant effect on the production of serotonin and the neurotransmitters GABA in the brain. These are very important hormones that control mood. They are also needed to prevent depression, pain, fatigue and anxiety ( 5 ).
4. Helps treat anemia. This element is necessary for the creation of hemoglobin in the blood. It also transports red blood cells throughout the body. This helps bring oxygen to the cells and mobilize iron. Anemia is accompanied by such symptoms: fatigue, dizziness, pain. Research shows that consuming pyridoxine may help reduce the symptoms of anemia. And in some cases, this element helps prevent this disease.
5. Protects eye health. In many cases, poor nutrition and nutritional deficiencies are the underlying causes of many eye diseases. Research has shown that taking vitamin B6 + folic acid can help prevent disease. It even helps prevent complete loss of vision.
6. Reduces symptoms of rheumatoid arthritis. Low levels of vitamin B6 are associated with increased symptoms of rheumatoid arthritis. Several studies have found that people with this condition need more B6 intake. This is because they experience constant muscle and joint pain due to chronic inflammation.
   
   
7. Helps in the treatment of hypertension. Some research suggests that taking this vitamin may help lower blood pressure in people with hypertension. This element increases blood flow and reduces its accumulation in the arteries.
8. Helps relieve symptoms of PMS. Consuming plenty of pyridoxine may help prevent painful period symptoms ( 6 ). Studies have shown that this element helps in the fight against chest pain, nausea, cramps, and fatigue. And even with acne, which is a harbinger of the menstrual cycle. For women who experience frequent PMS symptoms, it is recommended to take B vitamins regularly. It is especially important to do this 10 days before menstruation.
9. Helps reduce nausea during pregnancy. Studies have shown that taking this element is effective in reducing the severity of nausea and morning sickness. Patients were monitored for 6 weeks (24 hours a day). They noted how they felt before treatment and with vitamin B6. After this time, there was a significant reduction in nausea compared with the placebo group ( 7 ).
10. Helps in the treatment of asthma. Some studies have shown that this vitamin reduces the subsequent occurrence of asthma attacks and reduces their frequency.
11. Helps regulate sleep cycles. This wonder drug helps the body produce melatonin, which is an important hormone that helps us fall asleep. Melatonin is responsible for giving us the opportunity to regulate our internal clock. So we know when it's time to wake up and when it's time to sleep.
12. Prevents the formation of kidney stones. Some experience shows that taking pyridoxine along with other minerals (including magnesium) is very beneficial. It helps prevent or even cure kidney stones.

Interaction of vitamin B6 with other drugs

This item may interact with medications. Therefore, if you are already taking any medications, be sure to consult your doctor.

The list of medications that interact with vitamin B6 is huge. This list can include:

• any drugs used in chemotherapy;
• cycloserine or isoniazid - used in the treatment of tuberculosis;
• hydralazine (Apresoline) - to treat high blood pressure;
• penicillamine - prescribed in the fight against rheumatoid arthritis;
• theophylline - used to treat asthma;
• antibiotics, including tetracyclines;
• antidepressants including elavil, desipramine, imipramine and norparmin;
• some antidepressants called monoamine oxidase inhibitors (they lower blood levels of B6).

I am sure that today you have replenished your knowledge of the vital elements. And they made real discoveries for themselves in relation to pyridoxine. Do not lose your qualifications - subscribe to updates. And drop the link to the article to your friends - this info will come in handy for them. And I say goodbye to you - until we meet again.

Vitamin B6 is present in animal and plant foods, and can also be produced in small amounts in the body. It plays an important role in blood formation and metabolism, so it is very important to prevent its deficiency. How you can enrich the body with this vitamin, read below.

Beans 0.9 mg
Chicken 0.9 mg
Sea buckthorn 0.8 mg
Marine fish 0.8 mg
Beef 0.7 mg
Yeast 0.6mg
Potato 0.3 mg
Raisins 0.27 mg

The substance is water soluble. The second name is pyridoxine. The definition of "vitamin B6" combines a number of separate forms, such as pyridoxine, pyridoxal, pyridoxamine, pyridoxal phosphate.

Once in the body and assimilated, the vitamin is sent to the tissues, where it is integrated into various enzymes. These enzymes catalyze the reactions of protein metabolism, the formation of various hormone-like substances, and other vital reactions.

Foods rich in vitamin B6

Sufficiently high dosages of vitamin B6 are found in many foods. Its most “favorable” sources are animal food: meat, offal, fish, eggs. Also, the substance is present in plant products, it is found in some quantity in nuts, cereal sprouts, cabbage, avocados, citrus fruits.

However, plants are quite poor in it, so that they cannot be considered full-fledged sources of its intake. There are only a few exceptions among them. For example, the pitaya plant and beans contain a lot of vitamin B6. In fruits, pyridoxine is found mainly in the skin.

Increased need for vitamin B6

An increase in demand occurs:

With great physical exertion
. For long-term chronic diseases
. In the cold season
. With frequent stress, high intellectual loads
. During pregnancy, breastfeeding
. With an excess of protein in the diet.

Absorption of vitamin B6 from food

The vitamin is well absorbed by the body. The greater the deficiency of this substance, the more actively it is absorbed. If too much pyridoxine enters, then it is not absorbed and excreted in the urine.

The absorption of vitamin B6 is impaired if there is little magnesium in the food (this macronutrient is found in green vegetables, cocoa, pistachios, etc.). It is for this reason that all vitamin B6 complexes that you can buy contain vitamin B6 along with magnesium.

Functions of vitamin B6 in the body:

. It is part of the enzymes responsible for the processing and assimilation of protein, the formation of other enzymes and a number of hormones, muscle growth
. Participates in the implementation of fat metabolism, ensures adequate consumption of fat reserves. This is the reason why vitamin B6 is included in many weight loss supplements.
. With the participation of pyridoxine, many reactions of energy metabolism are carried out
. Vitamin B6 is important for hematopoiesis, the formation of hemoglobin and red blood cells, and the performance of their functions by red blood cells.
. The substance is involved in the formation of neurotransmitters - compounds that carry out the transmission of impulses in the nervous system
. Has anticonvulsant activity
. Positively affects the tone of the uterus, prevents the occurrence of excessive tone, which in pregnant women can lead to miscarriage
. Participates in the formation of nucleic acids - the genetic material of the human body
. Supports youth
. Strengthens the immune system, contributes to the full implementation of its functions
. Participates in carbohydrate metabolism, glucose uptake by cells; improves the effects of insulin, prevents the development of diabetes
. Helps lower blood cholesterol levels
. Improves liver function.

Signs of a lack of vitamin B6

The following signs indicate that a person needs additional use of vitamin B6:

Anemia
. Fatigue, weakness
. Periodically occurring feeling of numbness, "crawling" in the limbs
. Loss of appetite
. Increased dry skin
. Seizures at the corners of the mouth.

During pregnancy, if vitamin B6 is not enough in the diet, and a woman develops hypovitaminosis, she may experience:

Increased tendency to become anemic
. Prolonged toxicosis
. Increased nervousness, irritability, mood swings
. Skin problems.

Signs of excess vitamin B6

It is impossible to achieve hypervitaminosis of pyridoxine, even if you actively consume foods with a high content of it. The formation of an excess is possible only if, intentionally or accidentally, high doses of vitamin B6 are taken. In this case, the appearance of nausea, vomiting, neurological disorders is likely.

When cooking, about a third of the vitamin is lost. However, one has to come to terms with this, since its main sources are animal products, and they are usually not eaten without preliminary temperature treatment.

Hypovitaminosis requiring the use of vitamin B6 can occur when:

Lack of animal products in the diet
. Lack of fresh plant foods
. Diseases of the digestive tract that reduce the absorption of nutrients
. Diseases accompanied by vomiting, diarrhea, loss of appetite.
. Taking a number of antibacterial drugs (they reduce the absorption of the vitamin and reduce its beneficial effect on the body).

Vitamin B6: price and sale

If your doctor has recommended that you take vitamin B6 or if you want to do it for prevention, you should choose the best and highest quality preparations containing it. Check out the assortment of our store; you can buy vitamin B6, other vitamins, as well as multivitamin and mineral complexes from us at the best price, on the most favorable terms.

Add the selected drug to the basket or place an order by phone. Delivery is possible throughout Russia.

How to use and what can replace the drug "Pyridoxine"? Instructions for use, analogues and its indications will be presented below. You will also learn about the general characteristics of this medicine, its contraindications and unwanted reactions.

Components of the drug and its form of release

Pyridoxine injections, instructions for use of which are in a paper pack, go on sale in glass ampoules. The active ingredient of this solution is. Also, the composition of the injectable medicine includes such an additional substance as water for injection.

It is impossible not to say that the drug in question can be purchased in the form of tablets (in jars of 50 pieces).

Main characteristics

What is the drug "Pyridoxine-Vial"? Instructions for use (injections should be prescribed only by a doctor) states that this is a drug that replenishes the deficiency in the body.

It is no secret to anyone that the mentioned element is an indispensable participant in all metabolic processes in the human body. It supports and normalizes the activities of the National Assembly.

The phosphorylated form of this drug is a coenzyme of a huge number of enzymes that affect the non-oxidative metabolism of amino acids (including transamination and decarboxylation).

How do Pyridoxine injections work? Instructions for use states that it affects the metabolic processes of cysteine, tryptophan and methionine, as well as glutamine and other amino acids. In addition, it is extremely important for histamine metabolism and the normalization of fat.

Kinetic properties

How is pyridoxine hydrochloride distributed in the human body? Instructions for use (injections are most often prescribed for intramuscular injection) states that after this substance enters the human body, it is immediately metabolized in the liver. As a result, such pharmacologically active derivatives as pyridoxaminophosphate and pyridoxalphosphate are formed. These components are distributed mainly in muscle tissues, as well as in the nervous system and liver.

Experts note that the drug in question is able to penetrate into breast milk and through the placenta. It is excreted through the kidneys and together with bile.

Indications for the introduction of the solution

In what cases do patients receive Pyridoxine injections? Instructions for use informs that this remedy is actively used for the prevention and treatment of vitamin B6 deficiency in:

• B6-hypovitaminosis, toxicosis in pregnant women;
• diabetes mellitus, leukopenia, dermatitis;
• diseases of the nervous system, herpes zoster, neurodermatitis;
• air and sea sickness, ;
• atherosclerosis, psoriasis and other conditions.

Contraindications to the introduction of the solution

In what cases can not Pyridoxine injections be given? Instructions for use does not contain a large list of contraindications. However, it should be noted that it says that this medication is forbidden to be used by those patients who have a high sensitivity to vitamin B6, and its intolerance is also observed.

The drug "Pyridoxine": instructions for use

Injections, reviews of which we will consider a little lower, should be given only after consultation with a specialist.

The duration of vitamin B6 therapy is determined by the severity of the disease and the type of disorder.

For prophylactic purposes, this remedy is prescribed in an amount of 40 mg per day.

How should I take Pyridoxine Oral? Instructions for use (injections and tablets have the same indications) states that such a remedy is also used to treat hypovitaminosis. For adult patients, it is prescribed at a dose of 80 mg four times a day.

Side effects after taking the medicine

In most cases, the drug "Pyridoxine" is tolerated by patients very well. In some cases, vitamin B6 can cause allergic reactions, as well as contribute to the hypersecretion of hydrochloric acid.

Interaction, overdose

In medical practice, cases of overdose with this drug have not been established.

The parallel use of this drug with "Cycloserine", "Isoniazid" and "Penicillamine" may reduce its effectiveness.

Incompatibility (pharmaceutical) of vitamin B6 with B12 and B1 has been noted.

The medication in question significantly reduces the anti-Parkinsonian activity of the Levodopa drug.

The combination of this drug with hormonal contraceptives may increase the plasma concentration of pyridoxine.

The use of "Pyridoxine" with phenobarbital and phenytoin reduces the concentration of these elements in the blood.

Special Information

With extreme caution, the medication in question is used for coronary artery disease, as well as for an ulcer of the digestive tract.

In severe violations of the liver, vitamin B6 in high dosages can cause a deterioration in its function.

Similar funds

What can replace the drug "Pyridoxine"? Instructions for use (injections are often replaced with a tablet form of this remedy) do not answer this question. Therefore, in the process of choosing analogues, you should consult a doctor.

Pyridoxine is vitamin B6. It is included in many combination products, including such as Magne B6, Gepasteril-A, Pernexin Elixir, Essentiale, Gepasteril-B and Lipostabil. It should also be noted that the analogues of this drug are: "Piridobene", "Vitamin B6", "Becilan", "Adermin", "Pirivitol", "Benadon", "Bedoxin", "Hexabetalin", "Hexavibex", "Hexabion" and others.

*registered by the Ministry of Health of the Russian Federation (according to grls.rosminzdrav.ru)

Registration number:

Trade name of the drug:

Dosage form:

Compound

Coated tablets

Tablet core:
active ingredients:
magnesium lactate dihydrate * - 470 mg;
pyridoxine hydrochloride - 5 mg;
Excipients: sucrose - 115.6 mg, heavy kaolin - 40.0 mg, acacia gum - 20.0 mg, carboxypolymethylene 934 - 10.0 mg, talc (magnesium hydrosilicate) - 42.7 mg, magnesium stearate - 6.7 mg.
Tablet shell: acacia gum - 3.615 mg, sucrose - 214.969 mg, titanium dioxide - 1.416 mg, talc (magnesium hydrosilicate) - traces, carnauba wax (powder) - traces.
* - equivalent to magnesium content (Mg++) 48 mg

Solution for oral administration
Active ingredients:
magnesium lactate dihydrate ** - 186 mg;
magnesium pidolate** - 936 mg;
pyridoxine hydrochloride - 10 mg;
Excipients: sodium disulfite - 15 mg, sodium saccharinate - 15 mg, cherry-caramel flavor - 0.3 ml, purified water up to 10 ml.
** - equivalent to total magnesium content (Mg++) 100 mg

Description
white, oval, biconvex film-coated tablets with a smooth, shiny surface.
Solution for oral administration: transparent brown liquid with a caramel smell.

Pharmacotherapeutic group

Magnesium drug.

ATX code: A11JB.

Pharmacological properties

Carefully
With a moderate degree of renal failure, as there is a risk of developing hypermagnesemia.

Use during pregnancy and lactation

Pregnancy

Clinical experience with the drug in a sufficient number of pregnant women did not reveal any adverse effect on the occurrence of fetal malformations or fetotoxicity.
The drug Magne B 6 ® can be used during pregnancy only if necessary, on the advice of a doctor.
breastfeeding period

Magnesium passes into breast milk. The use of the drug during lactation and breastfeeding should be avoided.

Dosage and administration

Adults are advised to take 3-4 ampoules per day.
For children over 1 year old (body weight over 10 kg), the daily dose is 10-30 mg magnesium / kg body weight (0.4 - 1.2 mmol magnesium / kg) or 1-4 ampoules.
The daily dose should be divided into 2-3 doses, taken with meals.
The tablets should be taken with a glass of water.
The solution from the ampoules before taking is dissolved in? glass of water.
Treatment should be stopped immediately after the normalization of the concentration of magnesium in the blood.

Attention
Self-breaking ampoules with Magne B 6 ® do not require the use of a nail file. To open the ampoule, take it by the tip, having previously covered it with a piece of tissue, and break it off with a sharp movement, first from one pointed end, and then from the other, first directing the end of the ampoule opened by the first at an angle into a glass of water, so that the second the tip of the ampoule was not above the glass. After breaking off the second tip of the ampoule, its contents will freely pour into a glass.

Side effect

Immune System Disorders

Very rarely (< 0,01%): аллергические реакции, включая кожные реакции.
Gastrointestinal disorders

Unknown frequency (according to the available data, it is not possible to estimate the frequency of occurrence): diarrhea, abdominal pain, nausea, vomiting, flatulence.

Overdose