Dosage of lazolvan for inhalation for children. Lazolvan solution for inhalation - instructions for use

For the treatment of diseases of the lower respiratory tract, inhalations are often prescribed through a nebulizer with Lazolvan. What is Lazolvan? It is a medicine with expectorant properties. He perfectly copes with the task assigned to him: liquefying sputum and improving its separation.

On the market you can find the drug in the form of tablets, syrup, ampoules for injection and solution for inhalation. The active component of Lazolvan is Ambroxol, which has the following series of actions:

  • Stimulation of sputum excretion processes, turning a dry cough into a wet one.
  • The process of liquefaction and excretion of sputum is greatly facilitated.
  • Stimulates the synthesis of surfactant - a component that has a protective function, protecting the lung tissue.
  • Ensuring access of antibacterial drugs directly to the focus of inflammation.

Indications and contraindications

Inhalations with Lazolvan through a nebulizer are prescribed for rhinitis, sinusitis, cystic fibrosis, bronchial asthma, acute and chronic bronchitis. It is strictly forbidden to use this drug during pregnancy, especially in the first trimester.

During the second and third trimester, mothers can use Lazolvan through a nebulizer, but with extreme caution and under the supervision of a treating specialist. With too long use or an overdose of the drug, headaches, nausea, vomiting, heartburn are possible.

For children suffering from atopy, Lazolvan is contraindicated in any form. It is also not recommended to use Lazolvan in combination with other drugs: For example, antitussives. However, it goes well with drugs that inhibit labor.

Dosage of Lazolvan for a nebulizer

In order to avoid side effects, the medicine cured, but “did not cripple”, you should strictly monitor the dosage of the drug. The table below shows the doses for one procedure.

The number of procedures per knock should not exceed three.

How to prepare a solution for a nebulizer with Lazolvan

Physiological solution acts as a solvent in the preparation of an inhalation solution with Lazolvan. First, physiological saline is introduced into the nebulizer flask, and then the drug. Everything is thoroughly mixed.

So, if we return to the table describing the dosage of the drug, then 3 ml of saline should be added to the indicated amount of the drug. The duration of inhalation should not be more than 5 days. Here's how to dilute Lazolvan for a nebulizer if prescribed.

How to do inhalations with Lazolvan in a nebulizer

In general, it is clear how to breathe Lazolvan through a nebulizer: under the supervision of a specialist, comply with all sanitary standards, as well as safety rules. It is pointless to do inhalations before going to bed. This is due to the stimulation of liquefaction of sputum and its excretion. As a result, there will be a cough and sleep will no longer work.

Also, you should not use the drug if the cough is wet and additional sputum thinning is not required.

Inhalations with Lazolvan for children through a nebulizer

Applying Lazolvan through a nebulizer ensures rapid delivery of the drug to the respiratory tract. Efficiency is achieved faster due to the spraying of the drug. Efficiency is achieved in newborns and in bedridden patients.

When using the drug, children need to be very careful. The solution should be drawn up in a ratio of 1: 2, its temperature should be as close as possible in its value to body temperature.

If we are talking about bronchial asthma in a child, then inhalations should be started after taking bronchodilators. Five days is the maximum that the drug can be used. If on the third day the result is not noticeable, be sure to contact your doctor.

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Acute respiratory diseases cannot be avoided by anyone. Their symptoms are familiar to everyone, cough, runny nose, body aches, fever. If left untreated, inflammation of the respiratory departments is complicated and can develop into a chronic form. It will help alleviate the condition, as well as soften the dry cough inhalation using Lazolvan in the form of a solution.

Release form and structure

Lazolvan solution for inhalation for children helps to relieve dry cough, turning it into a wet one. When wet, mucus comes out better.


Compound:
  • The main element is Ambroxol. In one bottle, its content is approximately 7 and a half milligrams;
  • Additional elements - citric acid, sodium hydrogen phosphate dihydrate, sodium benzalkonium, distilled water.

The solution itself may be colorless, light brown. It is sold in vials of one hundred milligrams or in ampoules of 2 milligrams. Most of the drug is subsequently excreted from the body in the urine within five days.

Indications for use in children

The solution for inhalation is prescribed for the treatment of all parts of the respiratory system. With pathologies of any form, accompanied by viscous sputum:

  • Obstructive disease of the alveoli;
  • With pneumonia;
  • Asthma with phlegm;
  • bronchiectasis disease.

In a nebulizer, it will help with any diseases with purulent accumulation. This drug helps to remove exudate.

How to use, dosage

A mandatory instruction is attached to the drug, which indicates not only the pharmacological properties, but also the dosage, as well as the rules for diluting and taking the solution through an inhaler.

Lazolvan in this form is suitable for use in a nebulizer of any configuration, except for steam. Before use, the drug is mixed with saline, strictly observing the ratio indicated in the instructions, based on the age group. The exact dosage must be agreed with the doctor. This is necessary to moisten the inhalation procedure.

Combination with saline

Ready-made saline can be bought at a pharmacy. This is a solution of sodium chloride (0.9 percent) diluted with purified water. You can prepare such a solution yourself. The shelf life of the resulting composition is no more than 12 hours in the refrigerator.

The ratio of the drug to the solution is one to one (1:1), but, as with the dosage, the doctor makes the proportions. Components are connected immediately before use. Dilute the medicine only once. Before each subsequent inhalation, the solution is made again.

Combination with other drugs

Lazolvan has practically no contraindications. However, it is ineffective or there is no effect at all if it is combined with other mucolytic components. An inappropriate combination can lead to difficulties with sputum discharge. A pediatrician can prescribe several drugs at once, especially with a dry cough and the presence of inflammatory processes.

First, you need to do procedures with bronchodilators that dilate the bronchi, and only then, with Lazolvan. After liquefaction and discharge of sputum, anti-inflammatory drugs are prescribed for administration. This approach is not uncommon in the therapeutic effect of obstructive bronchitis. To enhance the therapeutic effect, you can make a procedure of 8 drops.

How to do inhalation in a nebulizer

Observing the indicated proportions, fill a special container in the nebulizer with the finished solution, following the instructions attached to the device. For children, the procedure is carried out once a day, but not before going to bed, as the liquefied sputum at the exit forms a cough.


Inhalations are carried out no less than an hour or an hour and a half after breakfast, lunch, afternoon tea. Breathe slowly and evenly. Taking too deep a breath can cause a coughing fit. At the end, within one and a half hours you can not go out or eat. Also, after the session, you should disassemble the device and sanitize the components (mask, tube, and so on).

If you need to do several procedures according to indications, then the break between each should be at least half an hour.

How many minutes to do inhalation, how many days

Lazolvan for inhalation dosage for children is prescribed by a doctor. On average, treatment takes a week. With further therapy, take a break for at least three days.

  1. Inhalations are recommended for infants as a last resort due to the inability to cough up sputum. Most often, they are prescribed the drug in the form of drops, which can also be diluted and taken orally. The dose of the given medicine is strictly prescribed only by a doctor.
  2. On average, the dose of the drug taken for children under 2 years old is 1 milligram of the finished solution.
  3. For children from 2 to 6 years old - two milligrams of solution per session.
  4. From six years and older, 3 milligrams of solution per day are prescribed.

It is necessary to apply the drug at a certain temperature - 20-21 degrees. Children under six years old need to breathe spray for no more than three minutes. At an older age, as well as for adults, the duration of the session is at least five minutes.

Children's Lazolvan is intended not only for children, but also for women in a position for the favorable development of the respiratory system of the unborn baby. Doctors do not recommend being treated with this drug, as well as being very careful about this procedure in the first three months after conception, and some advise resorting to "inhalation" only after the 23rd week.

The components of the drug pass into the mother's milk, so therapy is prescribed only if it is absolutely necessary. During pregnancy and lactation, the drug should be diluted in a similar way.

Contraindications

It is not uncommon for Lazolvan to be taken orally, as there are a number of restrictions for its use:

  • If nosebleeds are observed;
  • At elevated body temperature (from 37.5 and more);
  • Deviations in the work of the heart, blood vessels and respiratory organs, including insufficiency;
  • With great caution appoint people with diseased kidneys;
  • With dysfunction of the liver and gallbladder;
  • With individual rejection of components.

People with an increased reaction of the bronchi, first you need to do inhalation with bronchodilators.

Despite the relative harmlessness of the components of Lazolvan, a negative reaction can manifest itself in the form of malaise, dizziness, mild nausea, slightly less often vomiting, the appearance of an allergic rash accompanied by itching, and anaphylactic shock.

When these symptoms appear, inhalation is immediately stopped.

Using inhalations for the prevention of acute respiratory viral infections and acute respiratory infections, one must remember that it is often impossible to resort to them, only according to the testimony of a doctor who will select, based on the individuality of the organism, the number of procedures, the dosage of the medicine.

Terms and conditions of storage

Lazolvan for inhalation is sold in pharmaceutical sections. The term of use is 5 years. In the open form, the medicine is stored for no more than 12 hours at a temperature not exceeding 25 degrees. Avoid direct sunlight, ultraviolet destroys the structure of substances.


In some recipes, you can find dosing in milligrams or in a certain number of drops. One milligram of Lazolvan is equal to 25 drops.

Lazolvan is one of the most popular expectorant drugs available in various forms, including as a solution for inhalation. In this case, the drug acts locally and practically does not enter the systemic circulation, which leads to a low incidence of adverse reactions. This form of the drug is the safest and is approved for use in children from birth, unlike syrup and tablets.

How does Lazolvan work?

The active ingredient in Lazolvan is Ambroxol. It increases surfactant production by the lungs and increases mucociliary clearance activity. At the same time, sputum becomes more liquid, and due to increased motor activity of the cilia of the epithelium of the respiratory tract, its evacuation from the bronchi is facilitated.

Ambroxol is not an antitussive drug. On the contrary, the cough is aggravated as a result of an increase in the volume and mobility of liquid sputum.

In some studies, it was noted that ambroxol is effective not only in acute respiratory diseases and exacerbation of chronic pathologies of the respiratory tract, but also as symptomatic therapy during remission. Against the background of continuous use of ambroxol for 2 months or more in patients with chronic obstructive pulmonary disease, a decrease in the number of exacerbations, as well as their duration and severity, was noted.

The drug is available in a 100 ml vial (1 ml solution contains 7.5 mg of the active substance).

Indications for use

The drug is indicated for acute diseases of the respiratory tract and exacerbation of chronic ones, occurring with the formation of difficult-to-separate sputum and a violation of its evacuation. These states include:

  • acute bronchitis and exacerbation of chronic;
  • pneumonia;
  • chronic obstructive pulmonary disease (COPD) during exacerbation and remission;
  • bronchiectasis during exacerbation and remission;
  • bronchial asthma.

Lazolvan Rino - instructions for use, how to use during pregnancy and children?

Contraindications

Lazolvan is a fairly safe drug with a narrow range of contraindications, which include:

  • pregnancy in the first trimester;
  • the period of breastfeeding;
  • individual hypersensitivity to ambroxol or other components of the drug.

With caution, Lazolvan is prescribed at later stages of pregnancy, for people suffering from renal and / or liver failure.

How to do inhalation?

In order to do inhalations with Lazolvan at home, you need to purchase a nebulizer. The equipment must be used correctly. Before use, be sure to read the instructions for the selected model.

Preparing the medicine at home is quite simple: 2 ml of solution must be placed in the nebulizer chamber (up to 3 ml for adults and children over 6 years old). The resulting volume is not suitable for inhalation, so it is necessary to dilute Lazolvan with 2 ml of saline (physiological sodium chloride solution). Its addition additionally moisturizes the air inhaled from the inhaler, which also has a therapeutic effect. One procedure lasts about 15 minutes, you need to breathe during inhalation calmly, at a normal pace. Inhalations with Lazolvan are performed 1-2 times a day.

Persons suffering from bronchial asthma are advised to inhale a short-acting bronchodilator (Berodual, Berotek, Atrovent, Ventolin) before the procedure in order to avoid the development of nonspecific bronchospasm. The drug contains benzalkonium chloride, which can irritate the respiratory tract.

Relief of sputum discharge is noticeable already in the first two days of treatment with Lazolvan. If there is no improvement within 4-5 days, you should consult a doctor.

Lazolvan cannot be used simultaneously with medications that suppress the cough reflex. Violation of the evacuation of a large volume of sputum formed during the use of Lazolvan can lead to aggravation of symptoms and the development of complications.

Side effects of the drug

Ambroxol is considered a safe drug, but side effects are still recorded when using it. The most common adverse reactions from the gastrointestinal tract:

  • vomiting, nausea;
  • diarrhea;
  • abdominal pain syndrome;
  • dryness of the mucous membranes of the oral cavity and oropharynx;
  • violation of taste perception (dysgeusia);
  • decreased sensitivity of the oral mucosa to any irritants.

Cough usually occurs along with a cold. But even after recovery, he can remain and even become very strong and obsessive. In such cases, it is recommended to carry out inhalations with special medicinal solutions. The use of the Lazolvan solution for inhalation will be optimal.

Solution "Lazolvan" is a mucolytic agent. It contains ambroxol, which significantly reduces the viscosity of sputum. Inhalations with this remedy will help get rid of bronchial asthma, various forms of bronchitis and alleviate the manifestations of chronic lung disease. When inhaled, the medicinal substance acts directly on the mucous membrane of the pulmonary tract.

By the way, with a dry cough, such inhalations are not recommended. They may not help, but harm the patient. In this case, inhalation promotes expectoration and is not indicated for dry cough.

How to carry out inhalations with "Lazolvan" and saline?

For inhalation, you should use the Lazolvan solution together. It is saline that can really improve the absorption of any medication. It is recommended to take the drug in 2 ml. Saline is added in the same amount. It is best to carry out inhalations a couple of times a day, but with very strong manifestations, the frequency of inhalations can be increased up to three times a day. The time for inhalation should be chosen in such a way that later the patient does not have to go out into the cold air.

Inhalation should be carried out two hours after a meal. You should try not to take deep breaths during this process, which can provoke a severe coughing fit. In bronchial asthma, the patient should first take bronchodilators to prevent an attack during inhalation. It may be necessary to warm the solution for inhalation of a patient with elevated body temperature. After the procedure, you should not eat for one hour. Usually, children's inhalation with "Lazolvan" and saline should last no more than three minutes.

Inhalations with the indicated drug and saline for pregnant women in the first trimester are strictly prohibited. And already in the second and third trimeters, such inhalations should be carried out only after a doctor's appointment.

It is unlikely that there will be a person who would not be familiar with a painful hoarse cough that does not stop day or night. It seems like a dry cough is starting to get wet. The chest is stuffed up and wheezing, as if someone is playing a damaged harmonica. Phlegm fills the bronchi, not wanting to go outside. Life experience and the advice of a doctor have taught that at this stage of the disease it is not advisable to take antitussive drugs (suppressing cough). There is a slightly different task. It is necessary to help the sputum to leave the bronchial tree. This will help inhalations with Lazolvan for adults and children with a nebulizer.

Lazolvan - what it consists of

The drug is officially registered in the Russian Federation, produced in Italy. The base is Ambroxol. In the pharmacy it can be found in the form of tablets, lozenges, children's syrup and a solution for oral or inhalation. Let's stop at the last one.


The darkened bottle is filled with 100 ml of solution. 1 ml (25 drops) corresponds to 7.5 mg of ambroxol. The bottle has a cap with a dispenser, a measuring beaker is attached. It is in a cardboard box, on which, in addition to the name, there is an inscription: "Improves sputum discharge."

Inside the bottle is a colorless transparent liquid with a bitter taste. Ambroxol is dissolved in water with the addition of citric acid, salt, sodium hydrogen phosphate and benzalkonium chloride.

Pharmacodynamics and pharmacokinetics

Lazolvan has two effects:

  • mucolytic;
  • expectorant.

It increases secretion in the bronchi. The amount of surfactant increases, the mucus liquefies. At the same time, it activates the cilia of the epithelial lining of the respiratory tract, which facilitates the transport of sputum outward and the transformation of cough into a productive one.

Regardless of the method of use, the main substance reaches its highest concentration in two hours, accumulating mainly in the broncho-pulmonary region.


About a third of the amount consumed passes through the liver, being metabolized in it. Ambroxol with metabolites are excreted in the urine for 5 consecutive days.

Indications for use

Broncho-pulmonary problems, accompanied by increased viscosity and difficulty in separating bronchial secretions:

  • bronchitis in acute and chronic stages;
  • pneumonia;
  • bronchiectasis;
  • bronchial asthma;
  • COPD

According to ICD-10, cough is an indication as a symptom.

Method of application and dosage

Lazolvan's solution is used in two ways:

  • drink;
  • used by inhalation.

In both cases, Lazolvan should be diluted. Instructions for use suggests using water, favorite juices, tea, milk for oral administration, but does not indicate the proportions in which the drug should be diluted.

You can make inhalations with any device, except for a steam inhaler.

How to breed

Consider how to do inhalation in a nebulizer. The dosage provides for two gradations by age:

  • up to 6 years - 1 ml of Lazolvan for 1 inhalation 2 times a day;
  • over 6 years and adults - 2 ml 3 times a day.

According to the instructions for use, the drug is diluted with saline 1: 1, that is, how many drops of Lazolvan, so many drops of saline. Adult children are recommended the same proportions of breeding.

How to do inhalation

Before inhalation, to ensure better volatility, bring the solution to body temperature.

Inhalation in a nebulizer does not force you to breathe deeply, calm inhalation of sprayed particles through your mouth is enough. Too deep a breath provokes reflex coughing shocks.

In the treatment of bronchial asthma, the same dosage is shown in the same dilution with saline, but before inhalation, you need to take a bronchodilator to prevent possible bronchospasm.

Usually within 4-5 days there is an improvement, if this does not happen, then you should consult a doctor.

The performance of inhalations does not depend on food intake.

The duration of inhalation administration of the drug does not exceed 7 days. The question of the need to continue treatment is decided by the doctor.

Contraindications and side effects

In addition to individual intolerance to the active substance and individual components, Lazolvan is not prescribed to pregnant women in the 1st trimester and to mothers who feed their baby with mother's milk. A teratogenic effect has not been proven in preclinical studies, but as a precaution and due to the penetration of the drug through the placenta and into breast milk, these situations are among the contraindications.

Side effects are most often observed from the gastrointestinal tract.

An uncommon and frequently encountered effect is taste perversion and decreased sensitivity in the mouth and throat.

Sometimes there is nausea, vomiting, diarrhea occurs, the stomach may hurt. Skin reactions are rare.
In later pregnancy, inhalations with Lazolvan are prescribed when the benefits of using the drug outweigh the expected risk to the pregnant woman and the fetus. The appointment is carried out only by a doctor with careful monitoring of the patient.

Caution is required when using the drug in individuals with signs of renal and hepatic insufficiency.

Older age and gender are not grounds for changing the dose of Lazolvan.

Overdose symptoms are similar to side effects, but more pronounced. The drug is canceled, they try to cause a gag reflex, the stomach is washed, if it was taken by mouth no later than 2 hours, symptomatic therapy is prescribed.

The effect on driving has not been studied.

The interaction of Lazolvan with antibacterial agents - amoxicillin, erythromycin, cefuroxime - showed an increase in the penetration of antibiotics to the site of inflammation.

Analogues

Full analogues in composition, form of release and pharmacological action:

  • Ambrobene;
  • Orvis Broncho;
  • Ambroxol.

Preparations differ from Lazolvan by different manufacturers and at a price. Identical packages of 100 ml containing 7.5 mg of ambroxol per 1 ml are sold at the price:

  • Ambrobene 187 rubles;
  • Orvis Broncho 170 rubles;
  • Ambroxol 100 ml 159 rubles, 40 ml 84 rubles

Ambroxol has a slight difference in dose. The dose for preschoolers is 2 ml, for older children - 4 ml per 1 inhalation. Accordingly, it is necessary to dilute 2 and 4 ml of saline.

Terms and conditions of storage

Lazolvan in pharmacies is freely available, sold without a prescription.


It does not require special storage conditions, room temperature is sufficient. It is necessary to exclude access to the drug to children. Can be stored for 5 years.