To restore the intestinal microflora drugs are inexpensive but effective. Bifiform for intestinal recovery

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The intestinal microflora is a very important part of the human body. First of all, this is the correct functioning of the immune system, but with an imbalance of microflora, other biochemical processes in our body also suffer. For example, the work of the digestive tract - a healthy intestinal microflora is involved in the neutralization of fatty acids, in the digestion of food, the dissolution of fiber and the hydrolysis of proteins, in the formation of an acidic environment in the intestine to prevent the reproduction of pathogenic microflora. Without the participation of normal microflora, vitamins are not synthesized and poorly absorbed by the intestines, the gas composition of the intestines and water-salt metabolism in the human body suffer. Also, a healthy microflora is involved in the processes of bile acid and cholesterol metabolism and regulates stool.


Composition of normal microflora

A healthy intestinal microflora is the optimal balance of bacteria that are involved in the digestive process and the immune system. Normally, in the human intestine there are about 500 types of microorganisms, from unconditionally beneficial to pathogenic. The approximate number of intestinal microflora is defined as 1014, or about 2 kilograms of microorganisms.

The normal intestinal microflora contains:

    bifidobacteria

    lactobacilli

    bacteroids

    Escherichia

    coccal flora (Peptococcus, Peptostreptococcus, Streptococcus, Staphylococcus)

    eubacteria

    clostridia

    yeast-like fungi

    Klebsiella

    enterobacteria

The two most numerous types of bacteria are bifidobacteria, which make up up to 90% of the intestinal flora, and lactobacilli, which account for up to 9% of the total number of microorganisms. Bifidobacteria - Gram-positive anaerobic (existing without oxygen) bacteria that help in the breakdown of carbohydrates, inhibit the development of putrefactive microflora, protect the body from toxins and prevent the formation of carcinogens. Lactobacilli are gram-positive microorganisms that live in the human intestine and take part in metabolic processes and in the breakdown of plant foods. All other microorganisms are normally present in a small amount (the ratio with beneficial microflora is 1:100), and do not have a negative impact on the human body.


Causes of imbalances in the intestinal microflora

The intestinal microflora is very sensitive to negative influences, so there are dozens of possible reasons for its imbalance. Let's talk about the most common.

Most often, the cause of the development of dysbacteriosis is a long-term or uncontrolled intake of antibiotic drugs. Antibiotics, killing harmful bacteria, also have a detrimental effect on the state of normal intestinal microflora, which quickly leads to imbalance and reproduction of putrefactive fungal and other pathogenic microorganisms. Restoring the intestinal microflora after antibiotics is not an easy task that requires effort and patience. What to drink after antibiotics to restore microflora will be described further.

The balance of microflora and the immune system are inextricably linked. With a decrease in immunity in the intestine, an active growth of opportunistic and pathogenic microflora begins. Systemic chronic diseases, acute infectious diseases, therapy with hormonal drugs and cytostatics, exposure to ionizing radiation lead to a decrease in immunity.

Dietary inaccuracies are among the common causes of imbalance in the intestinal microflora. So, this is a diet with a predominance of carbohydrates, fats and animal proteins and with a minimum of fiber, dairy products, fresh vegetables and fruits. In this case, fermentation processes rapidly develop in the intestine, which leads to the growth of pathogenic and to the suppression of beneficial microflora.


How is the imbalance of intestinal microflora manifested?

The fact that a person needs drugs to restore the intestinal microflora after antibiotics, or exposure to other negative factors, is indicated by the following symptoms:

    Chair disorders. Most often, this disorder is manifested by diarrhea due to excessive formation of bile acids, increased intestinal motility and impaired absorption of fluid by the intestinal walls. The stool in this case acquires a putrid odor, mucus, an admixture of blood, and undigested pieces of food can be observed in it. With the development of dysbacteriosis in older people, constipation is possible, caused by a violation of the motor function of the intestine due to a lack of normal microflora. Disorders of the stool are accompanied by bloating and "rumbling" of the abdomen.

    Cramping pains. Pain in dysbacteriosis occurs due to an increase in pressure inside the intestine, the intensity of pain decreases after defecation or active gas discharge.

    Dyspeptic disorders. With dysbacteriosis, belching, loss of appetite, nausea, and occasional vomiting are almost always observed.

    Allergic reactions. Restoration of the microflora of the stomach and intestines will be required for allergies in the form of skin itching and rashes that appear even after eating foods that have not previously caused an unfriendly reaction. Such manifestations can be caused by a violation of the intestinal microflora and a decrease in its antiallergic properties.

    Signs of general intoxication of the body. These can be headaches and joint pains, sleep disturbances, general lethargy and weakness, fever up to 37-37.5 degrees.

Symptoms of hypovitaminosis. With an imbalance of the intestinal microflora due to a violation of the processes of synthesis and absorption of vitamins in the intestines, such manifestations of ill health as dryness and pallor of the skin, delamination of nails and hair loss, stomatitis, "jamming" in the corners of the lips can occur.

What is dangerous imbalance of intestinal microflora

With the development of dysbacteriosis in children, they gain weight poorly, often suffer from colds, and may lag behind their peers in physical and psychomotor development.

For adults, an imbalance in the intestinal microflora can lead to protein metabolism disorders with excessive absorption of fats and weight gain, cause the development of iron deficiency anemia and such chronic diseases of the gastrointestinal tract as gastritis, colitis, gastroduodenitis. Against the background of constipation arising from dysbacteriosis in older people, hemorrhoids and anal fissures can develop. Long-term metabolic disorders, which is typical for dysbacteriosis, increase the risk of developing diabetes.


Preparations for restoring the natural intestinal microflora

Means to restore the intestinal microflora after antibiotics or other imbalance factors should always be prescribed by a doctor. In the arsenal of modern gastroenterologists there are different groups of means for restoring the intestinal microflora. All of them are divided into three main groups - probiotics, prebiotics and synbiotics.

Prebiotics are drugs that have bifidogenic properties - they create a nutrient medium in which beneficial bifidus and lactobacilli multiply. The drugs in this group include, for example, Hilak Forte drops.

The best probiotics to restore the intestinal microflora, or eubiotics, are preparations that contain living components of the normal microflora that compensate for the deficiency of bifidobacteria and / or lactobacilli. The drugs in this group are Bifidumbacterin and Lactobacterin. These are common and inexpensive preparations for restoring the intestinal microflora. Both prebiotics and probiotics are generally taken 2-3 times a day.

The most promising drugs for the restoration of intestinal microflora belong to the group of synbiotics, and contain both prebiotics and probiotics. Synbiotics simultaneously replace the deficiency of normal intestinal flora and stimulate its growth, creating favorable conditions for the life of bifidobacteria and lactobacilli. An example of an inexpensive but effective drug for restoring intestinal microflora is Maxilak. It contains 9 different strains of beneficial microorganisms that make up the normal intestinal flora, and their concentration in one dose (4.5 billion) allows you to take the drug only 1 time per day. When choosing what to drink to restore the intestinal microflora, be sure to remember Maxilak! Beneficial microorganisms in its composition, thanks to the innovative protection technology of the MURE® capsules, begin to work exactly where it is needed - in the intestines, successfully overcoming such natural barriers as gastric juice, the effects of bile acids and digestive enzymes.


Diet in violation of the balance of intestinal microflora

Even the best preparations for restoring the intestinal microflora require adherence to a diet for the entire period of treatment of dysbacteriosis. It is important to exclude alcohol, spices, spicy seasonings from the diet, significantly limit fatty, fried foods and smoked meats, as well as any foods that enhance fermentation processes in the intestines. These products include pickles (including homemade) and marinades, muffins and sweets. It is important not to eat foods that promote increased gas formation - carbonated drinks, any legumes, bran bread, fresh vegetables and fruits. The basis of the diet during the restoration of intestinal microflora after antibiotics in adults and children should be low-fat varieties of fish and meat, weak broths, vegetable soups and baked vegetables, cereal cereals, sour-milk products, especially enriched with biocultures.

The functioning of the intestines affects the general well-being of a person, his immunity and appearance. Suppression of the activity of beneficial microorganisms leads to disruption of the work of this organ, the level of toxins increases. As a result, a person's stool is disturbed and health worsens. How to restore the intestinal microflora?

It is necessary to contact a specialist, he will prescribe the necessary medicines. Supporting the intestinal microflora will ensure good immunity and digestion.

Beneficial microorganisms act directly on the processes of fat metabolism, absorption of beneficial and nutrients, decomposition of proteins and bile acids.

A variety of microorganisms live in the human gastrointestinal tract, they colonize the large intestine. Under the intestinal microflora is understood the totality of such beneficial microorganisms:

  • bifidobacteria;
  • lactobacilli;
  • lactobacilli;
  • bacteroids.

Beneficial microflora should make up 99% of all microorganisms inhabiting the intestines, only 1% are pathogenic bacteria.

Causes of violation of the intestinal microflora

The intestinal microflora is very sensitive to various influences of external and internal factors. Such a violation is characterized by a quantitative and qualitative change in its composition, in medicine this situation is called dysbacteriosis.

Experts identify several reasons for the violation.

Treatment with antibacterial drugs is a common cause of dysbacteriosis. Antibiotics are harmful not only to pathogens, but also destroy beneficial bacteria.

Addiction to bad habits - smoking and drinking alcohol.

Improper nutrition, when the diet is dominated by fatty and spicy foods, as well as sweets.

Intestinal hyperactivity - too frequent emptying of it leads to washing out of beneficial microflora. This often happens when a person uses laxatives uncontrollably.

Previously transferred infectious diseases can also negatively affect the intestinal microflora.

Emotional loads of a negative nature.

Violation of the hormonal background, treatment with hormonal drugs.

Symptoms of dysbacteriosis in adults

Symptoms of an imbalance in the intestinal microflora are different:

  • unstable chair;
  • pain sensations;
  • bloating;
  • weakness;
  • headaches;
  • cramps in the stomach;
  • deterioration of the skin, hair and nails;
  • depression.

The stool in violation of the microflora becomes unstable and often turns into the form of diarrhea. The problem manifests itself in the occurrence of pain in the lower abdomen, as well as excessive gas formation.

With dysbacteriosis, the absorption of vitamins and other useful substances worsens, this is expressed by external manifestations - the skin, hair and nails deteriorate.

The predominance of pathogenic microflora in the intestines leads to poisoning by the body of the waste products of bad bacteria, so a person feels constant weakness, fatigue, and headaches. Such manifestations gradually turn into depression and apathy.

Children's symptoms of dysbacteriosis

Dysbacteriosis often manifests itself in newborns, the situation is due to the peculiarities of their development during this period - intestinal sterility and an unstable balance of microflora.

In children who are bottle-fed, as well as in premature babies, the risk of dysbacteriosis is increased. In older children, microflora disorders are caused by other factors - an unbalanced diet or past infections.

In childhood, the pathology under consideration is manifested by the following disorders:

  • diarrhea or constipation;
  • lack of appetite;
  • allergic skin rash;
  • lethargy and apathy.

With dysbacteriosis in children, undigested food is often present in the feces and the stools have a putrid odor. Children under 2 years of age may not gain weight, and an infant with this disorder is very restless, sleeps poorly and cries for no reason.

Ways to restore balance

Patients can restore the intestinal microflora in various ways. To get rid of the problem, you need a strict diet, with which foods are excluded. It is recommended to increase the intake of foods containing a lot of fiber to restore the microflora.

In addition to changing the diet, special medicines and traditional medicine will help restore the intestinal microflora.

To restore the intestinal microflora, the doctor often prescribes drugs of two groups - and prebiotics. These drugs normalize the intestinal microflora in different ways.

Probiotics help restore by increasing the number of beneficial bacteria, fill the intestines with lactobacilli and lactic acid microorganisms. All these components are contained in the preparations. Against the background of taking probiotics, pathogenic microflora is destroyed by beneficial bacteria.

Prebiotics restore otherwise, they create a favorable environment for the active reproduction of beneficial bacteria. Therefore, to get the maximum effect from probiotics, their intake should be combined with prebiotics. This will contribute to the speedy restoration of the intestinal microflora.

Probiotics are also prescribed for preventive purposes to those people who have been treated for another disease with antibiotics.

Popular Probiotics and Prebiotics

The range of drugs for the normalization of intestinal microflora is quite wide. Prebiotic preparations are presented in various dosage forms: suspension, syrups and tablets.

One of the sought-after restorative drugs is lactulose-based products:

There are also combined prebiotic preparations, they contain enterosorbents. In addition to creating favorable conditions for the growth of beneficial bacteria, they remove toxins from the intestines, these include Maxilak and Laktofiltrum.

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from 304 rub.
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Probiotics can be dry and liquid, but in the second case, these are suspensions and solutions that are not dried. They contain live bacteria and substances that feed them. This form of probiotics acts immediately after entering the human body.

Dry probiotics are specially dried, and this medicine is in the form of a fine powder, tablets or suspension for preparation. The action of dry probiotics begins a few hours after ingestion.

Probiotics can be monocomponent, polycomponent, combined, and also sorption. The most popular probiotics are:

  • Polybacterin.
  • Bifiform.
  • Bifidobacterin-Forte.
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from 196 rubles
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In some cases, to normalize the intestinal microflora, it is not enough to take probiotics and prebiotics. Treatment of dysbacteriosis sometimes requires supplementing therapy with special enzymes. This applies to those cases when a person has chronic diseases of the gastrointestinal tract.

As a result of intestinal inflammation, the digestion process worsens, enzymes will contribute to better absorption of incoming food. Digestive enzymes have a beneficial effect on the overall functioning of the digestive tract. The most popular of them are Mezim.

The correct use of traditional medicine will help improve the intestinal microflora. Garlic oil will help restore the flora in the large intestine. To prepare it, you need to take 5-6 cloves of garlic and grind them to a mushy state. The resulting mass is transferred to a glass container and poured with a glass of vegetable oil.

The finished mixture should be put in the refrigerator for one day, such a remedy is taken with each meal.

A delicious way to improve the intestinal microflora is a mixture of dried fruits. For these purposes, prunes and dried apricots are suitable, dried fruits are crushed in a convenient way, diluted with a small amount of honey. Various herbal infusions and decoctions have a good effect. For this purpose, plantain, calamus root, dill seeds are used.

Dairy products and their benefits

Gut microflora support is often provided through the intake of fermented milk products. They are enriched with various bacteria that have a beneficial effect on the state of the intestinal microflora, they relieve dysbacteriosis.

To restore or improve the intestinal microflora, it is necessary to establish a regimen and quality of nutrition. The patient needs to enrich the diet with fresh vegetables and fruits, as well as whole grain cereals.

You should refrain from spicy salty and fried foods, as well as sweets and staples. Food should be stewed, steamed or boiled. For recovery, the intake of fermented milk products is mandatory.

Treatment of dysbacteriosis and restoration of intestinal microflora is a long process, but achievable. The combination of proper nutrition, taking prescribed medicines and the use of alternative methods of treatment will ensure success in normalizing the condition of the intestine.

Video: How to restore the intestinal microflora

If not each of us, then most of us have encountered such an ailment as dysbacteriosis. Especially often dysbacteriosis occurs in young children - infants, as well as in people who use malnutrition in the diet. Also, dysbacteriosis is a consequence of:

  • uncontrolled use of antibiotics, which leads to the destruction of beneficial bacteria of the intestinal microflora, due to which the intestine ceases to function correctly;
  • past intestinal infections (dysentery, salmonellosis), operations on the stomach and intestines, diseases of the digestive system (gastritis, intestinal diseases, peptic ulcer, cholelithiasis, pancreatitis), which weaken the immunity of the gastrointestinal tract;
  • malnutrition contributes to the appearance of failures in the gastrointestinal tract, constipation and diarrhea, improper digestion and assimilation of food;
  • general decrease in the body's immunity.

All these factors contribute to a change in the composition of intestinal microorganisms and lead to the appearance of dysbacteriosis. This is due to the fact that there are fewer beneficial bacteria - bifidobacteria, lactobacilli, bacteroids, and more bad ones. Dysbacteriosis can be prevented and cured by taking drugs for dysbacteriosis: intestinal biocenosis is not fatal, and it is quite possible to live with it, but it is difficult, since not only the processes of the gastrointestinal tract are disturbed, but also general well-being.

Probiotics and prebiotics


For the prevention and treatment of dysbacteriosis, drugs are used that are divided into probiotics - drugs with a high content of bacteria that stop the reproduction of pathogenic microbes, and prebiotics - substances that promote favorable reproduction and growth of microflora. Prebiotics and probiotics, in turn, are divided into groups depending on their basis.

Probiotics based on lactobacilli

Preparations from this subgroup are in tablet form - Lactobacterin, and powder forms - Acylact, Biobacton. There are also rectal suppositories - Atsilakt suppositories. Suppositories, unlike the powder form of Atsilact, do not adversely affect beneficial bacteria in the intestines. These drugs are perfectly combined with antibiotics, however, being monopreparations (drugs that include only one medicinal enzyme), they do not provide a comprehensive recovery and protection of the microflora in a complex type of dysbacteriosis.

Probiotics based on bifidobacteria

The oldest drug of its kind, however, has a huge variety of drugs. The assortment of this type of probiotics includes Bifidumbacterin forte tablets (not compatible with antibiotics while taking medications), and powders - Probifor. Bifidumbacterin is also available in the form of suppositories for rectal use and concentrated suspension. Tablets and rectal dosage forms of bifidoprobiotics are not recommended for children under three years of age, in other cases, consult a doctor.

Probiotics - a combination of bifido - and lactobacilli

Florin Forte is a type of probiotic in powder form. The drug can be taken by both children and adults. For infants, the drug, according to the dosage established by the doctor, is mixed with breast milk or a mixture, adults take it with meals. The medicine must be stored at a temperature not higher than + 10 ° and not lower than 0 °. An ideal storage option would be a refrigerator. The medicine should not be taken with certain types of antibiotics that affect the correct functioning of Florin Forte (consult your doctor). Linex has a similar "complete set" of bacteria. It is also enriched with the bacterium Enterococcus faecium, which helps to have a complex effect on the microflora. The drug can be taken in conjunction with antibiotics, can not be stored in the refrigerator and is approved for use by pregnant and lactating mothers. In addition, Linex has no age restrictions. For infants, the powder from the capsule should be dissolved in warm boiled water.

You need to know that these drugs contain high doses of eubiotics, so for people with pronounced immunodeficiency or predisposed to allergies, the use of the drug is possible only after prior consultation with a doctor and at a dosage determined by him.

Probiotics based on bifidobacteria in combination with other bacteria

The most widely known drug for dysbacteriosis from this group of probiotics is Bificol in powder form, which also includes Escherichia coli bacteria. In addition to Bificol, this group includes Bifiform, which, in addition to the mentioned bacteria, has Enterococcus faecium. For complete passage of the gastrointestinal tract and reaching the intestines, the drug is available in the form of capsules with a protective shell that allows you to maintain stability in an acidic environment. A significant advantage of Bifiform is its compatibility when taken with antibiotics, which Bifikol cannot boast of. Bifiform is not recommended for children under two years of age. If you insist on the use of this particular drug, and the child is not yet two years old, consult a doctor.

Prebiotics based on lactulose

The action of these prebiotics is based on the breakdown of fructose-galactose disaccharide into low molecular weight organic acids in the microflora of the large intestine, which causes a decrease in blood pressure and suppression of the activity of harmful intestinal microflora. Representatives of this group of prebiotics are: Duphalac (syrup and powder), Portalac, Normaze syrups, Romfalac. This type of prebiotic is approved for infants, pregnant and lactating women. Contraindicated in people with intolerance to galactose, fructose, with rectal bleeding and intestinal obstruction. Patients with diabetes can take the drug only with the permission of the attending physician.

Prebiotic preparations

This group includes drugs that regulate the balance of intestinal microflora. Medicinal representatives of this group: Hilak forte (contains lactobacilli Lactobacillus acidophilus and helveticus. The preparation contains lactic acid, which can restore acidity in the gastrointestinal tract. Hilak Forte also contains short-chain fatty acids, which are responsible for restoring the intestinal microflora, contribute to a better restore the epithelium of the intestinal wall and balance the water-electrolyte balance.Hilak Forte has no age restrictions in the treatment of intestinal dysbacteriosis, and is compatible with antibiotics.

A complete list of drugs for dysbacteriosis

The above drugs are not the only drugs of their kind for dysbacteriosis. In the treatment of the disease, drugs from the following list will also help:

The best among the best

Undoubtedly, all the preparations for intestinal biocenosis described above carry out prevention or even eliminate dysbacteriosis. But, as already mentioned, some drugs have their drawbacks, for example, incompatibility with antibiotics or the inability to use drugs for infants. What drug for dysbacteriosis is the best * of its kind? To identify the best, you should analyze the most popular drugs for dysbacteriosis according to the following list:

  1. the presence of a capsule shell (the capsule shell does not allow the drug to dissolve before it enters the intestine);
  2. contraindications;
  3. side effects;
  4. interaction with antibiotics;
  5. use during pregnancy and lactation;
  6. age restrictions;
  7. storage method.

Lactobacterin (tablets and powder)

Acylact (tablets, suspension)

Biobacton

BifidumBacterin

Probifor

Hilak Forte

*- the best drug among those participating in the analysis

According to the analysis, we can conclude that the best drug for the treatment and prevention of dysbacteriosis is undoubtedly the drug Linex, Hilak Forte is in second place, Lactobacterin and Biobacton share third place, Probifor is fourth, and Acelact is fifth. Bifidum Bacterin is the last, sixth place among drugs for the prevention and treatment of dysbacteriosis.

Thus, it is necessary to approach the treatment of dysbacteriosis thoroughly and “with a head”. These drugs should be taken only as directed by the doctor and according to the dosage prescribed by him.

(also called eubiotics ) are living microorganisms that, in the normal state of the intestine, form it. These are the so-called non-pathogenic, that is, beneficial bacteria and yeasts that can counteract pathogenic or opportunistic microorganisms.

These intestinal microorganisms perform useful functions: provide the production, vitamin K , . Bacteria also determine the restoration of normal microflora in the mucous membranes of the body and in the gastrointestinal tract, protect the body from the influence of toxic elements, and strengthen.

That is why, with a change in the quality and quantity of the bacterial composition in the intestine, dysbiosis , and, as a result, a variety of diseases, both in children and in adult men and women.

It is very important to choose the right pills to restore the intestinal microflora. If a person has symptoms antibiotic-associated diarrhea , you can buy probiotics, since Linex analogues are effective means. But still, many scientists argue that until today there have not been enough studies that would clearly confirm which probiotic of this group is the best for a certain disease or condition of the body.

Currently, several generations of drugs are being produced that normalize the intestinal microflora.

  • First generation - monocomponent drugs, the composition contains only one strain of bacteria (, ).
  • Second generation - self-eliminating antagonists ( Baktistatin , ).
  • third generation - multicomponent drugs, which contain several strains of bacteria and additives at once ( and its analogues, Lebenin and etc.).
  • fourth generation - bifid-containing adsorbed probiotics ( , ).

Also, a list of probiotic preparations can be compiled according to the genus of those bacteria that are part of them. The main probiotics (the names of drugs that are best known to patients) are produced in Russia. There are several foreign analogues - Bifiform , Enterol , and etc.

However, it is sometimes difficult to determine which probiotics are best, because about a fifth of expensive dietary supplements do not contain as many beneficial live microorganisms as the instructions indicate. Also, some strains cannot settle in the human intestine for a long time. In addition, it is better to buy domestic preparations, as imported probiotics often contain bacterial strains that are not adapted for people living in Russia or Ukraine.

Therefore, the guide for the purchase of the drug should not be user reviews about which medicines are better to buy, but the appointment of a specialist.

It should be taken into account for those who are prescribed probiotics that this is a remedy that, if used incorrectly, can lead to the development of serious complications and provoke cholelithiasis or urolithiasis , cytokine imbalance . Therefore, despite the fact that a large list of such drugs is sold without a prescription, a specialist should tell you what probiotics are and how to take them.

There is a wide range of probiotics for the gut. To choose the best probiotics for the intestines, it is necessary to take into account their composition. In another way, probiotics are called eubiotics. Discussing what eubiotics are, what they are, we define two types of bacteria that are part of drugs and support the microflora. That is, eubiotics are drugs that include bifidobacteria or lactobacilli. However, the list of eubiotic drugs is quite wide, and some of them include both lactobacilli and bifidobacteria ( Bifidolactobacterin and etc.).

Prebiotics

It should be taken into account when using prebiotics that this is a tool that is used to treat various pathological conditions of the intestinal flora. Prebiotics - These are drugs that are prescribed in the probiotic correction scheme as an additional treatment. Prebiotics for children and adults are prescribed for and other pathological conditions.

For children, it is usually used , as well as its analogues, pantothenic acid , inulin preparations etc. A more complete list of prebiotic preparations, as well as information on which one is best for children to drink, can be obtained from a doctor.

Biologically active additives

Biological products are Russian, imported and special - designed for children. About which of them should be preferred to adults or given to children, it is advisable to consult a doctor.

Additives of domestic production These are not drug substitutes, but health products that correct the intestinal microflora. The cheaper remedy Normoflorin B and L (prices - from 200 rubles), as well as Bifacil , Biovestin , Polybacterin , Euflorin , Vetom , liquid concentrates of bifidobacteria, Laminolact , Biovestin Lacto , normospectrum , noxygelon , Probionic .
Imported additives Primadophilus , acidophilus , Probionix , Flora Dofilus , immunosymbiolact comp., Yogulact , , Kolifagina Pro .
Special dietary supplements for children These are dietary supplements that have special formulas:, Preema Kids ; domestic production - Bifidumbacterins-multi for children,.

When using any of the additives ( Vetom , Probionix , Rela Life ) instructions for use must be carefully observed.

First generation probiotics

If the baby has developed dysbacteriosis of the 1st degree, you can correct the microflora with the help of medicine Bifidumbacterin , as well as the drug La whobacterin . They are also used for prophylactic purposes. Which drug to prefer, it is better to ask the pediatrician. But if, in addition to dysbacteriosis, a child has an acute intestinal infection, sorbents and other biological products should also be given to the baby. Application of the product it is advisable for colitis of the torpid course. Therefore, it is almost never used for infants. Newborns receive Bifido and Lakto preparations diluted in cool boiled water, they are diluted at the rate of 1 dose - 1 tsp. water. The infant receives the solution half an hour before or receiving the mixture two to three times a day.

Also, this list of monopreparations includes analogues of this drug, since these drugs include acidophilus bacillus, which demonstrates activity against opportunistic and pathogenic microbes. However, from the point of view of chronology, Biobacton is not attributed to the first generation, since it is a more modern medicine. It is recommended to give it to children from the first days of life, who have viral and bacterial infections of the intestine, dysbacteriosis due to intake.

Bifidumbacterin dry

Capsules, tablets, powder for solution are produced. The composition of the product includes living bacteria bifidum.

Lactobacterin dry

A lyophilisate for solution is produced. The composition contains acidophilic lactobacilli.

The drug is Russian-made, you can buy at a price of 100 rubles.

Colibacterin dry

A lyophilisate for solution is produced. The composition of the product includes dried live bacteria of Escherichia coli strain M17, gelatin-sucrose protective mixture.

A Russian-made drug can be bought in Moscow at a price of 240 rubles.

Biobacton dry

A lyophilisate for solution is produced. The composition of the product includes acidophilic lactobacilli.

Russian-made drug.

Narine

Produced in the form of capsules. There are also other types of this drug - Narine Forte, Narine milk concentrate. The composition includes an acidophilic form of lactobacterin.

Produced in Armenia, cost from 170 rubles.

Primadophilus

Produced in the form of capsules. There are also other forms of the drug. Contains Lactobacillus acidophilus and Lactobacillus rhamnosus.

Produced in the USA, the cost is from 700 rubles.

Second generation probiotics

Probiotics are preparations for microflora of the second generation, which contain yeast-like fungi and spores of bacilli. Despite the fact that these components are not part of a healthy microflora, after they enter the gastrointestinal tract, they perform the same functions as beneficial live bacteria, suppressing pathogenic microorganisms. As Wikipedia and other resources testify, these drugs are used primarily for children suffering from acute diarrhea non-infectious origin, as well as subcompensated dysbacteriosis and mild intestinal infections. You can take such medicines for no longer than 7 days, then live bacteria for children are also recommended for use.

In preparations and Flonivin BS contain bacillus spores B.Cereus IP 5832 , showing a wide range of antibacterial activity. Once inside the stomach, spores are practically not affected by gastric juice, their transition to vegetative forms occurs in the intestine. As a result, the microflora is restored.

In preparations Baktisporin and contains hay stick Bacillus subtilis 3H. It is a live active antagonistic strain, which is selected for the property of chromosomal resistance to rifampicin .

In the preparation Enterol contains saccharomycetes (yeast-like fungi). It is used to treat diarrhea that has developed as a result of antibiotic treatment. The activity of Enterol in relation to clostridia has been proven.

In the remedy Biosporin includes lichieniform bacilli.

The composition of the tool Eubicor includes inactivated yeast culture, dietary fiber, minerals. The drug is a dietary supplement.

Produced in capsules. The composition contains B.cereus IP 5832 freeze-dried spores.

Produced in France, you can buy at a price of 550 rubles.

Produced in the form of a suspension, lyophilisate. Contains an active strain Bacillus subtilis, which demonstrates resistance to rifampicin .

Produced in Russia, you can buy at a price of 350 rubles.

Biosporin

Produced in the form of tablets and lyophilisate. The composition includes aerobic saprophytes belonging to the genus Bacillus: B. subtilis and B. Licheniformis.

Russian-made drug, cost - from 250 rubles.

Enterol

Produced in the form of capsules and suspensions. Contains Saccharomyces Boulardii lyophilized, lactose monohydrate, magnesium stearate, gelatin, titanium dioxide.

French-made drug, cost - from 250 rubles.

Eubicor

The dietary supplement is produced in the form of a powder. Contains inactivated yeast culture Saccharomyces cerevisiae, dietary fiber, amino acids, vitamins, trace elements.

Means of Russian production, cost - from 350 rubles.

Third generation probiotics

The list of third-generation probiotics includes combined products consisting of several symbiotic strains of a certain type of bacteria ( Acylact , Acipol ) or different types of bacteria ( Bifiform , ). In such a combination in one agent, bacteria act more actively. Also, some combined products differ in that they contain active ingredients that enhance the activity of the probiotic.

Yes, in the Acipola contains a polysaccharide of kefir fungus, in bififorme - lactulose, Bifilize - the monosaccharide lactose or lysozyme. Relating to the third generation of probiotics, agents are used as a treatment for acute intestinal infections of moderate severity. In severe cases, such probiotic agents are prescribed for use in complex treatment.

Linex Sachet capsules for children, Linex capsules, Linex Baby powder are produced. The composition contains bifidobacteria, lactobacilli, enterococci.

The product is produced in Slovakia. Cost - from 350 rubles.

Bifiform

Several forms of the drug are produced: Kids chewable tablets, Baby drops, Compex, Kid. Enterococci are also part of the Baby remedy. In addition to these components, Baby and Kids products additionally contain vitamins , AT 6 .

The products are manufactured in Denmark. Cost - from 350 rubles.

Bifiliz

Produced in the form of rectal suppositories, lyophilisate for suspension. The product contains bifidobacteria bifidum and lysozyme.

Russian-made drug, cost - from 500 rubles.

Acipol

Produced in the form of capsules, tablets, lyophilisate. The composition contains acidophilic lactobacilli, kefir fungi.

Russian-made drug, cost - from 300 rubles.

Acylact

Produced in the form of tablets, suppositories, lyophilisate for suspension. The composition of the product contains acidophilic lactobacilli.

Russian-made drug, cost - from 150 rubles.

fourth generation probiotics

The probiotics of this group are Florin Forte , Probiform , . These are adsorbed probiotics, which include bifidobacteria immobilized on particles. The difference with conventional probiotics is that they provide a more pronounced protective effect.

Means prescribed in the case of acute respiratory viral infections, gastroenterological diseases with dysbacteriosis of varying degrees. The drug has a detoxifying effect. It should be noted that the drug is contraindicated in lactase deficiency, gastroenteritis, provoked by rotavirus infection.

Probifor - an effective medicine for detoxification and treatment of diarrhea. The drug contains ten times more bifidobacteria than Bifidumbacterin Forte. To date, the remedy is prescribed in the case of severe forms of acute intestinal infection as the only means of etiotropic therapy. It is also practiced to treat diseases of the colon, dysbacteriosis with this drug. When conducting studies on the effectiveness of Probifor in shigellosis, it turned out that it acts in the same way as fluoroquinolones, 3rd generation antibiotics, the list of which includes several names.

When taking Probifor, the same effect is observed in acute diarrhea in patients in intensive care, as with the combined use of Enterol and Bifiliz.

Other preparations containing lactobacilli and bifidobacteria are also known. This is a Super 8 probiotic, etc.

Produced in the form of capsules and powder. The composition contains bifidobacteria adsorbed on activated carbon.

Russian-made drug. Cost - from 150 rubles.

Probifor

Produced in the form of capsules and powder. The composition contains bifidobacteria bifidum adsorbed on activated carbon.

Russian-made drug. Cost - from 450 rubles.

Florin Forte

Produced in the form of capsules and powder. The composition contains lactobacilli, bifidobacteria bifidum, sorbed on activated carbon.

Russian-made drug. Cost - from 430 rubles.

Synbiotics (combined drugs)

A wide range of drugs is currently offered synbiotics . These are medicines that contain both probiotics and prebiotics. What is the difference between these components can be understood by determining what they are - probiotics and prebiotics.

Probiotics are non-pathogenic microorganisms used to restore the flora of human organs, while influencing detrimentally on pathogenic and opportunistic organisms.

Prebiotics are substances that are not absorbed in the small intestine and that stimulate the growth of normal intestinal microflora, creating favorable conditions for this process.

When taking synbiotics, it should be taken into account that in this case prebiotics and probiotics are contained in one preparation.

What is the difference between such drugs and conventional probiotics? After entering the intestines, probiotics normalize the microflora, however, after a while they can die, and the composition of the microflora deteriorates again. Prebiotics, on the other hand, nourish beneficial bacteria, ensuring their active reproduction and protection from external influences.

Sometimes these drugs are also called symbiotics . Before taking symbiotics, what it is, the doctor should explain to the patient. After all, the list of symbiotic drugs includes various drugs, and a specialist should choose the most suitable one.

biological additive Maxilac contains a prebiotic component - oligofructose , as well as nine cultures of beneficial bacteria: three cultures of bifidobacteria, 4 cultures of lactobacilli, 1 lactococcus, 1 streptococcus.

Most often, the composition of the microflora changes in quantitative and qualitative ratio due to malnutrition, abuse of antibiotics and alcohol, under constant stressful conditions for the body, and also due to ionizing radiation. Often, dysbacteriosis is observed after past illnesses against the background of a decrease in immunity, general tone. An imbalance in the intestinal flora can become a prerequisite for the development of diabetes mellitus, lead to hormonal disruptions, disorders of the digestive tract, cardiovascular system, etc. To restore the microflora, daily consumption of fermented milk products is not enough, therapy with specially designed drugs to combat dysbacteriosis is required.

The microflora in its normal state is called normoflora. It is a combination of populations of various microbes, microorganisms living in antagonistic symbiosis with the carrier, the main function of which is the formation and constant maintenance of the resistance of the human body to diseases, the prevention and avoidance of the risk of colonization of internal organs by pathogenic bacteria. The microflora maintains the biochemical, immunological, metabolic balance necessary for health.

Also, the microflora is called the intestinal microbiota or microbiome. The largest part of the microbiome is concentrated in the large intestine, especially in the distal intestine.

On a note! Up to 10 enteric viruses can be present in the large intestine.

In a smaller amount, microorganisms inhabit the small intestine (except for the sterile proximal section), in a small amount due to the aggressive environment, acid-resistant lactobacilli and bifidobacteria are present in the stomach. There is no microflora in the duodenum due to the presence of digestive enzymes that aggressively affect microorganisms.

Table. Groups of microorganisms inhabiting the large intestine

GroupKinds
Basic/Obligate (up to 90-95%)Bacteroides, bifido-, lacto- and propionic acid bacteria.
Concomitant/optional (up to 5%)Enterococci, clostridia, eubacteria, strains of Escherichia coli, Pseudomonas.
Residual/transient (ideally up to 1%)Proteus, staphylococci, fungi of the genus Candida, protozoan viruses. Species with a high aggressive potential can be kept, which become more active and increase the population, provided that the protective functions of the main group of microorganisms of the microbiota decrease.

On a note! In an adult, the weight of the microflora can be up to two and a half kilograms. The number of microorganisms is up to 1014 CFU/g.

Signs of dysbacteriosis

Dysbacteriosis is a violation of the mobile balance of the microbiota inhabiting the intestine. With dysbacteriosis, the species composition of bacteria changes qualitatively and quantitatively. Alternatively, microorganisms of the obligate group may disappear due to the prolonged dominance of viruses, fungi, bacteria, which in a healthy person should make up only a small percentage of the total.

Form of the diseaseDescription of what happens in the body
Latent or compensatedThere are no pathological processes.
SubcompensatedInflammatory processes are manifested locally.
DecompensatedIn the liver, lungs, kidneys, spleen, thyroid gland and pancreas, metastatic foci are formed as a result of a decrease in the body's resistance and the spread of pathological processes. There is intoxication, a high probability of sepsis.

Principles of the treatment

To stabilize the intestinal microflora, first of all, it is necessary to deal with the treatment of existing diseases of the digestive system. If you do not get rid of the cause of dysbacteriosis, then it will be possible to take drugs that improve the microflora indefinitely without much effect.

In the process of treating existing ailments, the patient is prescribed a course of antibacterial agents, antibiotics, multivitamins, antihistamines, etc. The course is selected individually for each patient by a doctor after studying the medical history, collecting an anamnesis, conducting diagnostics, and making a diagnosis.

Important! There is no single standard treatment regimen. Therapy is carried out depending on the forms, phases of dysbacteriosis, the patient's condition. Treatment is carried out by a gastroenterologist.

In cases where the patient was shown enteral antibiotics, to normalize the intestinal microflora, drugs are recommended that do not affect the symbionts present in the intestine, for example, Neo-Enteroseptol tablets with antiprotozoal and antibacterial effects.

Method of application and dosage of the drug "Neo-Enteroseptol"

Also, the treatment of dysbacteriosis is carried out using bacterial preparations, which include a full-fledged viable microflora and components that are antagonistically active against pathogenic intestinal bacteria.

Table. "Colibacterin"

CriteriaDescription
Release form optionsDry powder (lyophilisate), from which a suspension is prepared for oral administration. The package contains 10 glass vials (ampoules). In 1 vial can be 2.3 or 5 doses.

The finished suspension is not stored and prepared immediately before use.

DosageThe drug is a course, treatment lasts from 1 to 3 months.

A second course of treatment is carried out no earlier than three months later and subject to a study of the microflora of the gastrointestinal tract.

Dry powder can be dissolved in any cold liquid (boiled water, compote, herbal decoction, warm tea).

Adults and children over three years of age take 2-4 doses three times a day orally 30-40 minutes before meals or one and a half hours after. For children 1-3 years old, the maximum daily dose of the drug is 8 doses, for babies 6-12 months old - 4 doses per day maximum.

One dose of lyophilisate should be dissolved in 1 tsp. liquids.

special instructionsTaking the drug with an existing allergic reaction can be started with small doses, no more than 1 at a time. After 1-2 weeks, you can begin to increase the dosage.

If the drug causes bloating and pain in the intestines, then within two weeks it should be administered by means of an enema, and after the specified period, switch to oral administration with a gradual increase in dosage to the recommended one.

"Colibacterin" is not used for ulcerative colitis.

Talitsa. "Bifidumbacterin"

CriteriaDescription
Release formVaginal and rectal suppositories, vials with lyophilisate, sachets, tablets and capsules. Available in packs of 3, 5 and 10 doses.
DosageThe course of treatment is at least two weeks, but not more than three months.
The drug is used 30-40 minutes before meals.
Dosage per day for oral administration:
- adults no more than 15 doses;
- newborns from 3 to 6 doses;
- children up to 6 months. 9 doses;
- children older than 6 months. 10 doses.
Intravaginally, the drug is used up to 8 days in a row, once a day, 5-10 doses. A sterile swab soaked in a solution of the drug is inserted into the vagina for 2-3 hours.
For topical application, a solution (2 doses) is impregnated with a swab, which is applied to the nipple half an hour before feeding the baby.
Suppositories use 1 pc. 2 times a day, no more than 10 days in a row.
special instructionsOne dose of powder should be dissolved in 1 tsp. liquids.
Do not dissolve the powder with hot water.
Antibiotics, when taken at the same time, weaken the effect of the drug.

Table. "Lactobacterin"

CriteriaDescription
Release formLyophilizate (powder) is packaged in vials of 5 doses. Suppositories are vaginal. Pills.
DosageTab. drink 2-3 r. a day half an hour before eating. Children are given 2-3 tablets each, adults - 5 each. The course of treatment is determined by the doctor and is no more than 25 days.
The powder is diluted with water in the same way as the preparations described above, 2-5 doses are used half an hour before meals, twice a day.
Suppositories are used intravaginally 1-2 times a day, no more than 10 days in a row.
special instructionsDo not use for candidiasis and for the treatment of children under 3 years of age.
Can be used with antibiotics.

Table. "Bificol"

CriteriaDescription
Release formThe lyophilisate from which the suspension is prepared is packaged in vials of 5 doses.
DosageThe dosage and duration of treatment is selected by the doctor depending on the patient's condition.
Treatment of children 6-12 months. spend two weeks in a row. The daily norm of the drug is 6 doses.
The course of treatment for children aged 1-3 years is 2-3 weeks. The daily rate is 10 doses.
Adults and children over three years of age are prescribed 10-15 doses daily for three weeks.
A second course of treatment is carried out only 2 months after the treatment, while the intestinal microbiocenosis is necessarily controlled.
special instructionsTaking antibiotics in conjunction with treatment with bificol is not recommended. During the course of chemotherapy, the drug is not used.
Contraindications: ulcerative colitis.

Analogues of the drugs discussed above:


The result of taking bacterial preparations is aimed at the following points:

  • suppression of the growth of fungi and pathogenic microflora, the destruction of toxins;
  • strengthening immunity due to the production of antibodies to viruses;
  • synthesis of vitamin K and the entire group B;
  • increase the digestibility of trace elements, nutrients.

For the treatment of dysbacteriosis, the use of drugs is indicated, the action of which is aimed at improving the digestive processes:


Video - Treatment regimen for intestinal dysbacteriosis after antibiotics

Prevention of dysbacteriosis

To normalize the composition of the intestinal microflora, it is recommended to use foods such as:

  • natural homemade yogurt without dyes;

  • kefir. To prepare a drink at home, kefir fungi are used, which are added to goat or cow's milk. After 2 days, the drink is filtered and drunk. You can sweeten kefir with half a teaspoon of honey;

  • sauerkraut. Only a product prepared at home through natural fermentation can improve the intestinal microflora. Cabbage cooked with preservatives and vinegar is not good;

  • tea mushroom, which has a beneficial effect on the balance of intestinal microflora.

To maintain the bacterial balance in the intestines, especially after antibiotic therapy, it is necessary to take probiotics regularly.