Actovegin is an antihypoxic agent that protects the nervous system. Actovegin analogue in tablets - a list of products similar in composition and mechanism of action Actovegin Russian analogue

Actovegin in the form of an ointment is a medicine that improves trophic processes in the body and tissue regeneration; the drug is intended for external use.

What is the composition of the medication Actovegin (ointment)?

The drug for external use is produced in a homogeneous white ointment, it is applied externally. The active component is a deproteinized hemoderivative extracted directly from the blood of calves.

The ointment's excipients are: white paraffin, purified water, added cholesterol, cetyl alcohol, methyl parahydroxybenzoate, and also propyl parahydroxybenzoate.

Actovegin ointment is produced in aluminum tubes of 50, 20, 30 and 100 grams, which are placed in cardboard packaging, where the date of manufacture of the product is stamped at the end of the box with the medicine in factory conditions. The medicine is sold without a prescription. The shelf life is five years, after which further use should be discarded.

What is the effect of Actovegin (ointment)?

The drug Actovegin is an antihypoxant; thanks to its active compound, the metabolism of glucose and oxygen in the tissues is activated. The use of the ointment causes an increase in energy metabolism inside the cell; under the influence of the active component, the consumption and utilization of oxygen and glucose increases.

Under the influence of the drug, ATP metabolism increases, and energy metabolism increases accordingly. As a result of using the ointment, the patient’s healing process is accelerated and the formation of new cells is stimulated.

What are the indications for use of the drug Actovegin (ointment)?

The drug Actovegin (ointment) instructions for use allows use in the following situations:

For the treatment and prevention of bedsores;
Weeping ulcers;
Ulcers that developed against the background of varicose veins;
For wounds and inflammatory diseases of the skin and mucous membranes, for example, with cracks, with chemical, solar and thermal burns in the acute stage, in addition, with cuts, scratches and abrasions.

In addition, the ointment is effective for skin lesions caused by exposure to radiation.

What are the contraindications for use of Actovegin (ointment)?

The drug Actovegin is contraindicated in case of hypersensitivity to the components of the medication. During pregnancy and lactation, the drug should be used after prior consultation with a doctor. Editorial team www.! After reading these instructions for use, also carefully study the official paper leaflet accompanying the drug. It may contain additions at the time of release.

What is Actovegin (ointment) use and dosage?

The course of treatment with ointment is designed for a period of at least twelve days and therapy continues throughout the entire period of so-called active regeneration. It is recommended to use Actovegin twice a day, treating the affected area directly.

The ointment is usually applied in a fairly thin layer to the damaged area. In order to prevent bedsores, it is recommended to rub the drug directly into the skin, which is in a high-risk area.

In order to prevent the appearance of radiation lesions on the skin, Actovegin ointment is applied to the skin in a thin layer after radiation therapeutic measures.

If there is no therapeutic effect from the use of the ointment, the patient should consult with the attending physician.

What are the side effects of Actovegin (ointment)?

Typically, the drug Actovegin is tolerated quite well by patients. In some patients, however, it is possible that adverse reactions may occur, which will be expressed in the addition of swelling and redness of the skin. In this case, you should stop further use of the ointment, after which it is important to consult a specialist. Editorial team www.! After reading these instructions for use, also carefully study the official paper leaflet accompanying the drug. It may contain additions at the time of release.

Overdose from Actovegin (ointment)

There are currently no cases of Actovegin overdose recorded. If the medicine gets inside, for some reason, and is swallowed by the patient, then it is recommended to promptly begin gastric lavage.

For this purpose, the affected patient must drink water to thereby induce vomiting. If after gastric lavage the patient experiences any discomfort, then it is recommended to consult a doctor in a timely manner, and the doctor will prescribe the necessary treatment.

Special conditions

The medicinal ointment should be used as prescribed by a qualified doctor. If you develop an allergy to the drug, it is recommended to refrain from further use, after which it is important to consult with your doctor.

It is worth noting that it is recommended to store Actovegin in accordance with the conditions specified in the instructions for the drug. If the drug is stored deviating from the norm, then the physicochemical characteristics of the drug may change, which will be expressed by a change in the consistency and color of the dosage form, in addition, the therapeutic properties of the drug will be lost. In such a situation, subsequent use of the product should be abandoned.

How to replace Actovegin (ointment), what analogues should I use?

The drug Curantil, as well as the drug Solcoseryl, are analogues; they should be used as prescribed by a qualified specialist.

Conclusion

It is recommended to use Actovegin ointment as prescribed by the treating specialist. If an allergic reaction develops, you should refrain from further use of the medication; in addition, in such a situation, it is important to consult a doctor in a timely manner.

Actovegin is a drug that helps improve metabolic processes in the body and also has the ability to regenerate new cells. The active ingredient is a special extract, which is obtained from the blood of young calves. Its peculiarity is that it completely lacks protein.

general information

This medicine is used in cardiology, psychiatry and neurology. Can be used as adjunctive therapy in dermatology and ophthalmology. Actovegin has a wide spectrum of action:

• promotes the process of healing and tissue restoration;
• has an antioxidant effect;
• improves blood microcirculation;
• makes cells more resistant to oxygen starvation;
• helps eliminate the effects of hypoxia.

This drug has several forms of release:

• gel;
• ampoules;
• cream;
• injection;
• pills.

Actovegin in the form of ointments, creams and gels is often used to treat dermatological diseases, wounds and burns. Injection solution and tablets are used for treatment of cerebral circulatory disorders, cognitive disorders and encephalopathy. The drug is also used for recovery after traumatic brain injury, surgery, after strokes and in cases of decreased vascular tone.

Despite the fact that Actovegin is an effective drug that is well tolerated, it can still cause some negative manifestations. Side effects may include:

• headaches;
• dizziness;
• gastrointestinal disorders;
• tachycardia;
• heart pain;
• hives;
• Quincke's edema.

If negative manifestations are observed, you should stop taking the drug and consult a doctor so that he can prescribe a drug similar to the active substance or change it altogether.

The average price in Russian pharmacies varies from 1200 to 1600 rubles depending on the dosage and dosage form of the drug. Not everyone can afford the drug at this price, so there are cheaper, but no less effective analogues.

Analogues of the drug

The only direct analogue is the drug Solcoseryl, the active ingredient of which is a hemoderivative from calf blood without protein. However, there is a slight difference, which is that the main ingredient is presented in the form of a dialysate. Despite this small nuance, Solcoseryl is a complete analogue.

Solcoseryl is used for the following medical indications:

• ischemic stroke;
• hemorrhagic stroke;
• consequences of severe traumatic brain injuries;
• trophic disorders.

Just like the original, Solcoseryl is available in a variety of dosage forms. It can be either an ointment, gel, cream, or an injection solution or tablets.

In ampoules

In addition to Solcoseryl, there are many other incomplete analogues, but they are similar in their pharmacological action. These drugs include Cerebrolysin and Cortexin.

Cerebrolysin is presented in the form of a peptide complex, which is based on an extract from pig brain. This is a medicine refers to nootropics, therefore helps improve energy aerobic metabolism in brain cells. The drug also helps synthesize protein in brain cells and protects neurons from the toxic effects of amino acids.

Cortexin refers to drugs that are developed on the basis of fractions and polypeptide complexes that are isolated from the brain of livestock. This drug is excellent for the treatment of acute and chronic circulatory disorders in the brain tissue, and is also taken for epilepsy and cognitive disorders.

In tablets

In tablet form, Actovegin has the following analogues:

• Vero-Trimetazidine;
• Chimes.

For the latter, the medications are absolutely the same. They are based on the myotropic vasodilator-dipyrimadol. This substance is used to improve blood microcirculation, as well as to reduce platelet aggregation, while it has a dilating effect on blood vessels.

Both Curantil and Dipyridamole help strengthen the immune system. Such medications increase interferon, which means the body has more strength to fight viral infections.

Vero-Trimetazidine is used to treat vascular disorders that may result from ischemia. This drug is taken in combination with other medications. Active substance - trimetazidine participates in the normalization of cell energy metabolism, and also helps maintain homeostasis during the transfer of potassium and calcium ions.

Ointments

A similar local medicine is Algofin. The composition is slightly different from the composition of Actovegin, as it contains proteins, namely chlorophyll-carotene paste. Despite this difference, this medicine can be a good replacement for the expensive Actovegin.

Algofin is used in the following clinical situations:

• bedsores;
• infected wounds;
• burns;
• abscesses;
• aseptic wounds;
• phlegmon;
• ulcers of the mucous membranes.

Top 10 best analogues

• Solcoseryl. The only drug that completely matches the active substance.
• Cerebrolysin- a drug that has a wide spectrum of action. Can be used to treat both adults and children.
• Cortexin- an antioxidant, nootropic drug, the active substance of which is peptides from the cerebral cortex of cattle. Often used to treat children.
• Mexidol- a drug that has an antioxidant effect. Available in two dosage forms: injections and tablets. It is actively used in psychiatry, for therapy for toxic effects on the brain or for neurotic disorders. This drug is also used to relieve withdrawal symptoms in alcoholics.
• Semax- a medicine that is produced in the form of drops. Used to treat brain lesions and neurotic disorders. This is an excellent remedy for preventing psychological fatigue and is used to reduce stress.
• Chime- a drug that helps improve microcirculation in the kidneys, brain vessels and retina. Used to eliminate hypoxia and platelet aggregation. Contraindicated for pregnant women.
• Vinpocetine, Telektol, Cavinton - medications that have the same active ingredient. They can be used for therapy in cases of cerebrovascular accidents, acute stages of stroke and ischemic attacks.
• Omaron. It contains two active substances: cinnarizine and piracetam. Omaron is used to treat depressive conditions, atherosclerosis, vestibular disorders, as well as retarded intellectual growth of a child.
• Ginkum- a natural remedy that is used to relieve stress, restore memory and attention. It helps eliminate tinnitus and relieves the consequences that may arise due to cerebrovascular disorders.
• Cinnarizine- a drug that is intended for therapy after ischemic strokes, traumatic brain injuries, as well as in the presence of vestibular disorders. Very often used for motion sickness and seasickness.

Composition of the medicine: deproteinized hemoderivative of calf blood - 200.0 mg in the form of Actovegin® granulate * - 345.0 mg,
Excipients: magnesium stearate - 2.0 mg, talc - 3.0 mg

Short description

The drug Actovegin is a drug that improves the body's metabolic processes. Promotes cell restoration and regeneration.

A demirative extract is isolated from the blood of suckling calves, which is completely free of protein compounds. This medicine is available in all pharmacological forms, except capsules.

The demand for the drug today is high. It is prescribed to restore metabolic and regenerative processes and improve cellular nutrition. A special method is used to produce a substrate from the blood of young calves, which is included in the composition of the drug.

The biological product is indicated for patients with diseases:
- vascular diseases of the brain;
- consequences of traumatic brain injury, concussion;
- dementia;
- neuronal deficiency;
— disturbance of peripheral circulation;
- damage to blood vessels due to nervous coagulation disorders;
- atherosclerotic/diabetic polyneuropathy.
It is prohibited for patients with diseases to take Actovegin:
- cerebral/lung edema;
- absence or deficiency of diuresis;
— myocardial decompensation;
- water is retained in the body.

The remedy normalizes blood supply and ensures the correct supply of substances needed by the body to the tissues. Existing analogues of Actovegin have lower prices and the same effectiveness. But substitutes in the form of injection solution and tablets are usually not cheaper than the original; the cost depends on the manufacturer’s brand and the components of the medicine. However, you can purchase generic Actovegin at an affordable price.

Russian analogues

Actovegin (injections) - taking this analogue allows you to stimulate and resume metabolic processes in the circulatory system. The product helps to effectively deliver oxygen and glucose to cells. The drug is often prescribed in the case of diabetic polyneuropathy of the extremities. The components of the drug allow cells to be adequately saturated with oxygen, helping to absorb and utilize it.
A course of treatment with Actovegin is prescribed to improve blood supply and saturate damaged tissues with oxygen and glucose. Moreover, this medicine is well tolerated by patients, as it does not have serious side effects and does not cause vascular disorders.

Mexidol - this drug is intended to improve blood supply to the brain, rheological properties of blood, microcirculation, increases dopamine content, and reduces platelet aggregation. The use of this substitute makes it possible to increase tissue tolerance to the lack of oxygen and protect cells from excess oxidation. There is also a gradual restoration of cell membrane lipids. The drug has an anticonvulsant effect, successfully suppresses the symptoms of anxiety, fear and anxiety.

This domestic analogue is an effective corrector of cerebral blood flow. The drug is prescribed to eliminate symptoms such as poor memory, dizziness, and inattention. The components of the drug contribute to the dilation of blood vessels and normalize the outflow from the veins. Application leads to improvement of metabolic processes in brain cells, normalization of blood pressure, and improvement of eye trophism. In addition, Bravinton prevents the progression of deafness of vascular origin, and at the same time increases intellectual productivity.

Korsavin is a drug that effectively improves brain metabolism and blood circulation in the brain. The analogue is used to treat blood vessels, cerebral atherosclerosis, as well as eliminate the consequences of a stroke. The medicine is also prescribed for idiopathic tinnitus, symptoms of hearing loss, and Meniere's disease. At the same time, Korsavin is effective in the treatment of chronic vascular diseases of the retina.

Imported analogues

Solcoseryl is a medicine that effectively transports oxygen and glucose to cells that are in a state of hypoxia. The use of the drug allows you to activate regenerative processes in tissues. Effective for frostbite, burns, skin injuries and bruises. The ointment is used exclusively on dry, non-wetting wounds. Moreover, the cost of this analogue in pharmacies is usually lower than the original drug.

Manufacturer: MEDA PHARMACEUTICALS SWITZERLAND GmbH (Switzerland)

Release form: Paste for topical use in tube

Active substance: Deproteinized hemoderivative

Prices in pharmacies: No current offers

This analogue is prescribed for symptoms such as erosions and oral ulcers, as well as for the treatment of gum diseases. The paste is effective with regular use: damaged tissues heal and regeneration occurs. It contains natural components, they help activate the functioning of blood vessels, which causes division and restoration of damaged cells. It also contains an anesthetic that provides an analgesic effect. The drug is prescribed for use by patients of any age.

The active component of the drug Cavinton is obtained from the periwinkle flower. The component is a plant alkaloid. This plant has long been used in folk medicine, as it has cerebrovasodilating and cerebroprotective effects. Thanks to the active component, metabolism and blood circulation in nerve tissues are significantly improved. The substitute has an antioxidant effect, blood properties improve, and has a pronounced nootropic effect.

This is a popular analogue of Actovegin, which is prescribed for hypoxia of brain tissue, as well as to activate blood circulation in the brain, as well as for patients with traumatic brain injury. The drug does not affect blood pressure and heart rate, and systemic circulation does not suffer. Used to improve metabolism in nerve tissues. The components of the drug promote healthy blood circulation in tissues. The peculiarity of Vinpocetine is that it acts exclusively on the affected part of the brain in ischemic pathology.

Oxygen deficiency in body tissues, which occurs due to poor blood circulation and absorption, leads to metabolic disorders and a decrease in the metabolic process. Actovegin activates these processes by accelerating the supply of glucose and oxygen to brain structures and increasing the production of adenosine triphosphoric acid. As a result, the energy functions of the body are normalized, since tissues at the cellular level receive optimal nutrition.

"Actovegin": indications and method of use

In North America and Western Europe, the drug is not used due to its composition, but in Russia and other post-Soviet countries it is successfully used for the following indications:

Impaired blood supply to brain structures;

Consequences of ischemic stroke;

Varicose veins;

TBI, which led to disruption of blood flow;

Skin infections and injuries that progress to necrosis;

Burns and ulcers of various etiologies.

Actovegin analogues with a similar composition can be used for the same indications.

Injections: at the beginning of treatment, the daily dose is up to 20 ml intravenously, after removal of acute symptoms - up to 10 ml intravenously or 5 ml intramuscularly.

Droppers: daily dose is up to 10 ml of Actovegin, diluted in 300 ml of saline solution or 5% glucose.

Tablets: three times daily dose of 1-2 pieces with an average duration of treatment of 1 month.

Analogs and substitutes for Actovegin

The price of Actovegin varies both down and up.

"Solcoseryl". The only drug that is identical in composition and rightfully belongs to the Actovegina category. It is available in price equivalent (the cost is several times less than Actovegin), and is available in the form of tablets, ointments and solutions for intravenous administration. Effectively used for skin lesions, head injury and venous insufficiency.

"Courantil". A product with a similar mechanism of action is used to restore blood circulation and increase vascular tone, but has a different composition from Actovegin and a higher price. "Curantil" should not be taken by persons suffering from heart disease and low blood pressure.

"Cortexin". Despite the similar pharmacological composition and action, the drug cannot be classified as “Actovegin analogues”, since its cost is much higher. At the same time, in addition to the general indications for Actovegin, Cortexin additionally has an anticonvulsant effect, reduces the impact of toxins on the brain during severe poisoning, restores memory, and increases stress resistance.

When choosing one of the drugs described above as a substitute for Actovegin, first of all, you need to take into account their effectiveness and safety, since the substances included in the composition have a direct effect on the structures of the brain and central nervous system.

There are restrictions during pregnancy