Nasonex hormonal drops against the runny nose and features of their use. Nasonex – use according to instructions and look for cheaper analogues Nasonex side effects

Name:

Nasonex

Pharmacological
action:

Belongs to the group of glucocorticosteroids. Apply topically. Like any drug in this group, it has anti-inflammatory and antiallergic effects. Correct dosing of the drug prevents systemic effects.

Mechanism of action consists of inhibiting the release of inflammatory mediators. Reduces the accumulation of inflammatory exudate at the site of inflammation due to the prevention of marginal accumulation of neutrophils (cells involved in the formation of the inflammatory response). This in turn reduces the production of lymphokines, inhibits the migration of macrophages, which helps to reduce the rate of infiltration and granulation processes. The drug also inhibits the development of an immediate allergic reaction (by reducing the release of mediators from mast cells responsible for inflammation and inhibition of arachidonic acid synthesis). When tested, the drug showed good results in the treatment of allergies and inflammatory processes.

With proper intranasal use, the systemic bioavailability of the drug (i.e., the amount that can enter the general bloodstream) is less than 0.1%. Moreover, even with the use of high-tech methods, the drug is not detected in blood serum. Nasonex is biotransformed in the liver.

Indications for
application:

Prevention of exacerbation of moderate and severe seasonal allergic rhinitis. The recommended time to start prevention is 2-3 weeks before the start of flowering of allergen plants;
- treatment of seasonal and year-round allergic rhinitis in children (from 2 years), adolescents and adults;
- treatment of exacerbation of chronic sinusitis in adults (including the elderly) and children over 12 years of age. It can be used as an adjuvant to the main treatment.

Mode of application:

For the treatment of seasonal and year-round allergic rhinitis Adults and children over 12 years of age are prescribed 2 injections into each nostril 1 time per day (total dose per day is about 200 mcg of the drug). When a positive clinical effect is achieved, it is recommended to reduce the dosage to 100 mcg per day (i.e., 1 injection per day in each nostril). The maximum possible dosage of the drug is no more than 400 mcg (i.e. 4 injections into one nostril) per day.

Children aged 2 to 11 years Prescribe 50 mcg/day in one nostril, i.e. the total daily dose of the drug is 100 mcg.
The first clinical signs of improvement are observed 12 hours after using the drug.

For the treatment of exacerbations of chronic sinusitis in adults(including elderly people) and children over 12 years of age, the drug is prescribed 100 mcg 2 times a day (i.e. 2 injections per day in each nostril). The total daily dose is 400 mcg per day. The maximum permissible daily dose is 800 mcg/day, i.e. 4 injections into each nostril 2 times a day, followed by a reduction in the dose of the drug, upon achieving a positive clinical effect.
Shake the bottle before use.

Side effects:

In the treatment of seasonal and year-round allergic rhinitis the following side effects were observed: in adults - nosebleeds, pharyngitis, burning sensation in the nose, irritation of the nasal mucosa. In children - nosebleeds, headache, feeling of irritation of the nasal mucosa, sneezing.
During treatment as an adjuvant for exacerbations of chronic sinusitis in adults and adolescents, the following were observed: headache, pharyngitis, sensations of irritation of the nasal mucosa, a burning sensation in the nose. Rarely, mild, self-limiting nosebleeds occurred.

Rarely During treatment with Nasonex, perforation of the nasal septum and increased intraocular pressure were observed.

Contraindications:

Hypersensitivity to any component of the drug;
- the presence of an untreated local infection involving the nasal mucosa;
- recent surgery or trauma to the nose (before the wound heals);
- tuberculosis infection (active or latent) of the respiratory tract, untreated fungal, bacterial, viral systemic infection or infection caused by Herpes simplex with eye damage (as an exception, the drug can be prescribed in these cases as directed by a doctor with great caution);
- children under 2 years of age (no data on safety of use).

Interaction
other medicinal
by other means:

Nasonex was used simultaneously with loratadine, there was no effect on the plasma concentration of loratadine or its main metabolite, and mometasone furoate was not detected in the blood plasma even at minimal concentrations. The combination therapy was well tolerated by the patients.
No data are provided regarding interactions with other drugs.

Pregnancy:

After intranasal use of the drug at the maximum therapeutic dose, mometasone does not determined in blood plasma even at minimal concentrations; therefore, it can be expected that its effect on the fetus will be negligible and its potential reproductive toxicity very low. However, due to the fact that special, well-controlled studies of the drug's effect in pregnant women have not been conducted, Nasonex should be prescribed to pregnant women, breastfeeding mothers, or women of childbearing age only if the expected benefit from its use justifies the potential risk to the fetus and newborn. Newborns whose mothers used corticosteroids during pregnancy should be carefully examined to identify possible adrenal hypofunction.

A runny nose is perhaps the most common ailment among children of different ages. In the autumn-winter period, it bothers all kids. In addition to acute respiratory infections or acute respiratory viral infections, rhinitis and sinusitis can be chronic or allergic in nature.

In the fight against constant and unpleasant nasal congestion, the drug Nasonex is often used. Despite the fact that the spray is an antiallergic medication, it is widely and successfully used to treat a variety of respiratory tract pathologies. How to properly use Nasonex for children? What is its effect on the body? How long does treatment last? When is the medicine indicated and what are its contraindications?

Nasonex nasal drops: properties and composition

Nasonex is a product of the Belgian pharmaceutical industry. The drug is a modern antiallergic drug of exclusively local action based on synthetic hormones (glucocorticosteroids).

The main active ingredient is mometasone fuorate, which belongs to the group of synthetic glucocorticosteroids (GCS). Mometasone is an artificial analogue of important hormones (glucocorticoids) produced by the adrenal glands. They participate in metabolic processes, affect the body's immune defense, and have anti-inflammatory properties.

Main properties of the drug:

1. eliminates signs of allergies (removes nasal congestion, blocks irritation of mucous membranes due to allergen exposure);
2. relieves swelling of various origins;
3. effectively relieves inflammation caused by allergies or other factors, including infectious ones;
4. protects against exposure to toxins.

The primary function of the drug is antiallergic. Once on the mucous membrane of the respiratory tract, mometasone prevents the production of specific inflammatory mediators, biological substances that trigger an unpleasant response to allergen exposure (itching, sneezing, swelling, runny nose, etc.).

In addition, the anti-inflammatory effect and the elimination of edema significantly improve well-being. The nasal passages expand, swelling and inflammation in the sinuses disappear, which allows a person to breathe normally and not feel discomfort. Due to these properties, the drug is used to treat other diseases.

Release form

Nasonex is available only in spray form. There is no division between adults and children. In this case, the course of treatment differs from the number and frequency of injections. The drug is a white or almost white suspension. The suspension is prepared by mixing mometasone powder and liquid auxiliary components.

The spray is sold in a plastic bottle. The kit includes a special spray nozzle. The manufacturer offers a choice of two types of volume - 60 (10 g) or 120 (18 g) doses (sprays). One gram of liquid contains 500 mcg of mometasone. The dispenser sprays are clearly defined, each injection contains 0.1 g of the drug, that is, 50 mcg of active substance.

Indications for use in children

Many mothers, hearing about a hormonal drug, get scared and refuse treatment. There is an opinion that hormones disrupt the normal development of the body, inhibit the functioning of the adrenal glands, and lead to weight gain. In fact, this is not so - correctly selected hormonal therapy, on the contrary, normalizes the functions of the body.

You need to understand that Nasonex acts exclusively locally, only on the mucous membrane of the respiratory tract. It is not absorbed into the bloodstream or tissues of internal organs. The influence of the medication on the functioning of organ systems or the general development of the child is completely excluded.

In addition, official research and testing of the medicine among children was carried out. According to the results, it was found that even with long-term use of the spray (from several months to a year), hormones do not affect growth and development.

Indications for the use of Nasonex to treat a child:

• runny nose of allergic origin;
• rhinitis, sinusitis or rhinosinusitis of infectious origin (most often bacterial);
• polyposis (growth of benign formations in the nasal cavity - polyps, which complicate the normal breathing process and worsen the quality of life);
• adenoids (we recommend reading:);
• sinusitis or other respiratory complications associated with inflammation and significant swelling.

To combat allergies, the drug is used as an independent remedy. In other cases, Nasonex is part of complex therapy (antiviral drugs, antibiotics, etc.) and acts as an auxiliary medicine.

Instructions for use: dosage and duration of use

The drug has certain features that require compliance with important rules when using it. For effective and safe treatment, the dosage of the substance must be strictly observed, which is why the medicine is available only in the form of a spray (when using drops, the amount of the product is always exceeded).

To achieve accurate injections, you need to carry out the so-called calibration or adjustment of the spray nozzle. A similar procedure is carried out before the first use or if the medicine has not been used for more than 2 weeks. To do this, you need to make about 10 presses into the air. With the help of calibration, a uniform and dosed injection of the substance is achieved. Shake the bottle thoroughly before each use. The suspension contains a powder that continually settles.

The use of Nasonex for children is allowed from the age of 2 years. The maximum permitted daily dose (tested) for a child from 2 to 12 years of age is 100 mcg. That is, children are shown one injection into each nostril once a day. After 12 years of age, the drug is used according to the treatment regimen for adults. The daily dose in this case is 200 mcg, that is, 4 doses per day.

If the medication is used correctly and all rules are followed, the visible therapeutic effect occurs within 12–14 hours. At the same time, its long-term preservation is noted.

Depending on the diagnosis, the course of treatment will differ only in duration and additional medications:

1. In case of allergies, you can spray your nose throughout the flowering season or year-round (if the reaction is not to pollen) (we recommend reading:). With long-term therapy, short-term breaks are possible.
2. For colds, the drug is used to relieve swelling and inflammation, which speeds up recovery. Typically, the spray is started when the main treatment does not give the desired result or the intensity of the symptoms is too high. The course of application lasts until symptoms disappear (no more than a week).
3. For adenoids (we recommend reading:). There are no instructions in the official instructions regarding the treatment of adenoids. However, in practice, many pediatricians and ENT specialists note the positive effects of the drug. The antiallergic properties of the glucocorticosteroid slow down and reduce the proliferation of the pharyngeal tonsils, as a result of which inflammation and swelling are relieved. The course of treatment is at least 4 months, sometimes almost a year.
4. For polyps (from 14 years of age). The drug is used for no more than 10 days, 2 times a day, 2-3 injections.

Long-term use of Nasonex is safe. It does not lead to addiction, does not reduce the body’s sensitivity to the drug, and does not affect development.

When is the drug contraindicated?

The drug has a number of contraindications for use:

• age under 2 years;
• individual intolerance or hypersensitivity to mometasone or other components;
• unhealed wounds or sutures in the nasal cavity (after injury or surgery);
• tuberculosis;
• the presence of an infection (bacterial, viral or fungal) caused by an exacerbation of herpes;
• the presence of a local infection of the mucous membranes.

Before starting to use the drug, you should consult your doctor and completely cure the above infections. This will eliminate complications or side effects.

The effect of Nasonex on children under 2 years of age has not been scientifically studied, and the spray form is inconvenient at such an early age (spraying the hormone can severely irritate the mucous membranes). Self-use at your own risk is strictly prohibited.

Sometimes, if there is a great need, doctors prescribe the drug a little earlier than 2 years. In this case, parents and specialists constantly monitor the health status of the little patient.

Possible adverse reactions

The instructions for use rank possible adverse reactions according to the likelihood of their occurrence. This means that there are a number of unpleasant symptoms that occur with moderate frequency, and there are others whose likelihood of occurrence is almost zero.

Most likely side effects:

• nosebleeds of moderate intensity, which pass quickly and do not require medical attention;
• inflammation of the mucous membrane - pharyngitis (occurs with prolonged use of the drug);
• burning, itching, unpleasant pain in the nasal passages (appear immediately after instillation, when the substance gets on the mucous membrane, and disappear within a short time);
• sneezing (short-term);
• irritation of the nasopharyngeal mucosa;
• headache.

Unlikely side effects:

• increased intraocular pressure;
• fatigue, lethargy, depression;
• dysfunction of the adrenal glands;
• Cushing's syndrome (chronic excess of glucocorticoids, which is manifested by weight gain, changes in skin condition, excessive hairiness in women, mental changes and other symptoms);
• pain in muscles and joints;
• the appearance of cataracts or glaucoma.

As for the possibility of a drug overdose and its symptoms, the instructions here do not provide a clear explanation. The manufacturer claims that an overdose of the active substance is almost impossible. The drug is sprayed in a clearly standardized quantity. With increasing doses, mometasone has low biological activity and acts only locally, that is, it cannot have a systemic effect.

Cost and analogues of the drug

Many people are concerned about the question: how much does the medicine cost and can it be replaced with an equivalent analogue? The drug cannot be classified as a cheap medicine. The price depends on the manufacturer, which has proven itself to be of high quality raw materials and the final product. The average cost of a bottle for 60 doses is 430–500 rubles, a large one for 120 doses is from 765 to 830 rubles.

Considering that a child needs only 2 injections per day for treatment, a small package is enough for 1 month, and a large package is enough for 2 months. However, for many reasons, parents often look for analogues to completely replace the drug.

Cheaper analogues of the drug with a similar principle of action:

• Rinoklenil,
• Avamis, (more details in the article:)
• Flixonase,
• Nasobek,
• Nazarel,
• Sinoflurin.

The advantages of Nasonex are undeniable - a high concentration of active substances, a long-lasting effect from inhalation and minimal possibility of side effects. However, if long-term use is required, the high price may become a problem.

You cannot choose a spray or drops from the above list yourself - this can slow down the healing process and harm your health. Drugs affect the body differently and may be ineffective for some diagnoses. You need to contact your doctor and ask for a cheaper replacement medication.

The most common analogues are Flixonase and Avamis:

• Flixonase contains a similar active ingredient and is of high quality and effectiveness, but its price is above average. The main drawback is the age restrictions (after 4 years).
• Doctors usually prescribe Avamis as a complete replacement. Its composition and action are almost identical to Nasonex, and the price is an order of magnitude lower. The medication can be used for adenoids - it shows positive treatment results.

Nasonex: instructions for use and reviews

When faced with any illness, it is important to learn as much as possible about it. Forewarned is forearmed. Having a full range of information about pathology, a person knows when to see a doctor, what symptoms to focus on, whether it is possible to get rid of health problems on one’s own, and what complications one should be prepared for.

The website provides information about various diseases, their symptoms and diagnostic methods, areas of therapy and a specific list of medications. Publications are created by us using reliable scientific sources and presented in an easy-to-understand manner.

In the first section " Traditional medicine» information materials on various medical areas are published. Second section " Health from colds» is dedicated to ENT topics and colds, as the most common diseases in the world. The third section “” (abbreviated N.I.P.) - the name speaks for itself.

We wish you pleasant reading and be healthy!

Sincerely, Site Administration.

Nasonex is a synthetic drug containing glucocorticosteroids, used topically for allergic forms of rhinitis, and is part of the complex treatment of sinusitis of various etiologies.

Before you start using the drug Nasonex, the instructions for use require detailed study to exclude the presence of contraindications.

Nasonex is a potent synthetic glucocorticosteroid used intranasally to relieve inflammatory processes.

Nasonex reduces elevated histamine levels, continuously released from destabilized mast cells, reduces eosinophil activity. There is a decrease in the total number of elements of allergic inflammation - neutrophils, eosinophils, epithelial cell adhesion proteins.

Numerous clinical trials of Nasonex have proven not only the safety of using the nasal drug among different age groups, but also its high effectiveness in the early and late stages of allergic rhinitis and sinusitis.

The pharmacological action of Nasonex includes:

• inhibition of the production of anti-inflammatory cytokines;
• increased synthesis of the lipomodulin enzyme;
• deactivation of the arachidonic acid cycle;
• stopping the metabolization of arachidonic acid breakdown products (cyclic endoperoxides, prostaglandins);
• decreased production of eosinophilic exudate;
• relief of neutrophil infiltration;
• decreased synthesis of lymphokines;
• inhibition of macrophage migration;
• elimination of infiltration and granulation processes;
• stopping the production of chemotaxis enzymes;
• inhibition of the development of anaphylactic reactions.

The pharmacodynamics of Nasonex occurs within the mucous membrane and submucosal layer; the lack of absorption into the systemic circulation limits the central effect of the drug and the development of side effects.

Release form and composition. Nasonex is produced by a Belgian manufacturer in the form of an intranasal spray of transparent or milky color in plastic dosed bottles of 10, 18 g, complete with a dosing device. A dosage of 10 g is equivalent to 60 doses, 18 g is equivalent to 120 doses. The active ingredient is mometasone furoate (micronized monohydrate), which determines the pharmacological action of Nazonex.

The composition contains the presence of excipients per 1 g:

• 2.04 mg citric acid monohydrate;
• microcrystalline cellulose;
• 21 mg dispersed cellulose;
• 20 mg glycerol;
• 82 mg polysorbate;
• 2.9 mg sodium citrate dihydrate;
• 0.2 mg benzalkonium chloride (55% solution);
• 950 mg purified water.

Mometasone furoate has a vasoconstrictor, antipruritic and antiexudative effect, relieves symptoms of hypersensitivity of the epithelium of the nasal cavity, prevents its drying out and the formation of cracks.

The lack of systemic absorption of the synthetic hormone of the glucocorticosteroid group prevents insufficiency of the hypothalamic-pituitary-adrenal system, even with long-term use.

The medication is stored in a dark, cool place to avoid the breakdown of the synthetic component. Before using the medication, consult an allergist or otolaryngologist.

Pharmacokinetics. Absorption into the systemic circulation of Nasonex after intranasal administration to the mucous membrane of the upper respiratory tract is less than 0.1% with a sensitivity of the detection method of 0.25 pg/ml.

If a part of Nasonex is accidentally ingested, the active component undergoes primary metabolization in the stomach, after which it binds to plasma proteins and is biotransformed into an inactive metabolite as a result of secondary biochemical breakdown in the liver, and is excreted in an inactive form by the kidneys.

The therapeutic effect on various diseases lies in the main pharmacodynamic effects of Nasonex:

1. For allergic pathology There is a gradual relief of eosinophilic inflammation, which causes the presence of characteristic symptoms. Complete blocking of the steady progression of allergic reactions prevents the development of typical complications and restores damaged mucous membranes. After a full course of treatment with Nasonex, promising clinical studies have proven a decrease in the body's sensitization upon repeated encounters with an allergic antigen. This is due to the stabilization of the outer membranes of mast cells, slowing down the release of histamine and stopping the metabolism of arachidonic acid.
2. For infectious inflammations paranasal sinuses Nasonex is used as an additional drug to relieve swelling of the nasal passages and maxillary anastomosis, which prevents the normal outflow of exudate from the nasal sinus cavity. The use of Nasonex increases the availability of specific intranasal drugs and increases the rate of remission.

The main indications for the use of Nasonex hormonal spray in adults and children over two years of age include:

For allergic inflammation of the nasal passages and turbinates, Nasonex is used year-round or during the exacerbation season in adult and pediatric patients.

When the clinical symptoms of bacterial or viral rhinosinusitis are erased, the drug is used as an auxiliary drug to improve the outflow of pus or mucus and restore the mucous membrane.

When adenoids enlarge in children above grade I-II, Nasonex is used as a desensitizing agent, relieves symptoms of swelling and hyperirritation of the nasopharynx. In older people, against the background of proliferation of polyps or granulomas, Nasonex relieves swelling, constant nasal congestion and facilitates the outflow of purulent contents of the sinuses.

Nasonex is contraindicated for:

• violation of the integrity of the epithelium of the respiratory tract (trauma, surgery, cracks, ruptures of synechiae);
• in children under two years of age;
• intolerance to the active components of the drug.

Under the supervision of a physician, Nasonex is used in women during pregnancy and lactation, if there is no risk to the fetus. Nasonex is not prescribed for tuberculosis of the respiratory system, chronic mycoses of the nasal sinuses and long-term bacterial sinusitis. This is due to the inhibitory effect of Nasonex on the healing processes of the mucous membrane due to inhibition of cellular reactions.

Side effects and overdose. To prevent negative reactions, the medicine should not be mixed with alcohol or carbonated drinks. Cases of overdose with Nasonex are rare, however, the drug is used to a limited extent with systemic administration of glucocorticosteroids.

Side effects:

• nosebleeds;
• migraine;
• burning, itching;
• sore throat;
• ulceration of the nasal passages;
• sneezing.

Side effects are extremely rare and require immediate discontinuation of the drug and consultation with a doctor. Compatibility with other drugs of mometasone furoate is satisfactory; the drug does not affect the pharmacodynamics of other medicinal compounds.

Which is better - Avamis or Nasonex? Glucocorticoseroid nasal products, produced by foreign pharmacological companies, have general indications for use.

Unlike Nasonex, Avamis has successfully passed clinical trials among pregnant women and nursing mothers and is approved for use in this category of patients. Avamis is contraindicated in acute respiratory viral pathology in patients of any age.

Nasonex is more widely used in otolaryngological practice due to the possibility of using the drug for bacterial and viral infections. The choice of a particular drug is made by the doctor individually, taking into account the indications and contraindications for each individual patient.

Nasonex's analogues:

• Asmanex;
• Gistan-N;
• Desrinitis;
• Momat;
• Avecort;
• Avamis;
• Elokom.

Prices for the original drug range from 800 to 1200 rubles for 120 doses in a bottle. The cost of analogs is much lower, for example, Avamis costs in pharmacies from 320 to 450 rubles for 120 doses. Prices for the drugs Elokom, Momat and Asmanex range from 240 to 610 rubles, depending on the pricing policy of the pharmacy where the purchase is made.

Reviews after treatment with Nasonex are positive, especially in the treatment of allergic seasonal rhinitis. Patients note rapid relief of nasal congestion, a decrease in inflammation and a general improvement in their condition, both with allergies and with chronic sinus polyposis.

Nasonex spray: method of use and dosage for adults and children

Nasonex spray is indicated for use in adult patients and children over two years of age as prescribed by a doctor for allergic rhinosinusitis and other diseases.

The active hormonal substance mometasone furoate has a pronounced effect against eosinophilic inflammation of the tissue of the mucous membrane of the nasal passages, turbinates and sinuses.

Intranasal glucocorticosteroid (GCS) has a pronounced antiallergic and anti-inflammatory effect, proven by multiple clinical trials with placebo. Long-term use of Nasonex does not cause insufficiency of the hypothalamic-pituitary-adrenal system, which is due to the lack of systemic action.

Method of administration and dosage of Nasonex in the treatment of allergic rhinosinusitis:

• adults, elderly and persons over 10 years of age in a therapeutic dosage of 50 mcg once a day, two inhalations (maximum dosage is 200 mcg per day);
• a child from two to ten years old is prescribed one inhalation (50 mcg) twice a day (daily dose up to 100 mcg).

When treating infectious inflammation of the paranasal sinuses:

• adults, elderly and persons over 10 years of age in a therapeutic dosage of 50 mcg 2 times a day, two inhalations (total daily dose is 400 mcg);
• for a child from two to ten years old, under the supervision of a pediatrician, one inhalation (50 mcg) three times a day (total daily dose is 150 mcg).

In the treatment of acute sinusitis without symptoms of bacterial infection (purulent contents in the nasal cavity) for adult patients and children over 12 years of age, treatment is carried out with 2 inhalations in each nostril, the maximum daily dose is up to 400 mcg. The therapeutic effect of the drug increases with the use of vasoconstrictor drops due to the removal of swelling of the mucous membrane.

Nasonex nasal spray is used primarily in adult patients to relieve symptoms of the disease. The jet under pressure promotes deep penetration of the active substance to the maxillary anastomosis of the maxillary sinus. Vasoconstrictor drops eliminate swelling of the mucous membrane and lead to maximum penetration of the active substance administered under pressure.

The use of the drug for inflammation of the paranasal sinuses located remotely from the nasal passages (ethmoidal labyrinth, frontal and sphenoid sinuses) is most relevant in the form of a spray, in this case the particles of the active substance penetrate quite deeply, irrigating the mucous membrane. Treatment is prescribed after performing diagnostic measures aimed at determining the fluid level.

If the patient requires puncture of the paranasal sinuses, Nasonex spray is discontinued until the mucous membrane at the puncture site has completely healed. As a rule, the drug is resumed after a course of antibiotic drops and systemic medications.

Nasonex Schering, produced in Belgium, is available in pharmacies in bottles with substitutes for the usual jet pressure, thanks to which each inhalation has an accurate dosage. This allows you to avoid an overdose of the drug and prevents the development of side effects.

Nasonex nasal drops: method of application and dosage

Nasonex drops are available in classic soft packaging without a dispenser attachment.

It is used as an adjuvant therapy for acute and chronic rhinitis, sinusitis and ethmoiditis.

For year-round or seasonal allergic rhinitis, Nasonex is highly effective due to its rapid anti-edematous effect, relieving swelling of the mucous membrane of the nasal passages and maxillary sinus.

Directions for use and dosage for allergic sinusitis:

• adults, elderly and people over 10 years old, 1-2 drops 3 times a day until symptoms completely relieve;
• for a child from two to ten years old, 1 drop 2 times a day.

For acute bacterial or viral sinusitis as maintenance therapy:

• adults, elderly and people over 10 years old, 2-3 drops 3 times a day for up to 14 days.
• for a child from two to ten years old, 2 drops 2 times a day for up to 7 days.

If a patient develops medicinal rhinitis due to dependence on vasoconstrictor drops, the hormonal drugs Nasonex or Avamis help restore the mucous membrane and eliminate unpleasant sensations (itching, nasal congestion). The medication is prescribed in childhood and adolescence for seasonal allergies to prevent the manifestation of symptoms.

Chronic sinusitis with the formation of granules or polyps is characterized by constant production of serous-purulent contents, atrophy of the mucous membrane and severe nasal congestion. The condition is dangerous due to the addition of a secondary infection, which significantly worsens the overall prognosis of the disease. Nasonex drops relieve local symptoms, prevent the proliferation of the mucous membrane, and inhibit the growth of polyps and granulomas.

In case of chronic pathology, drops are prescribed only on the recommendation of the attending physician. to select the dosage that is most effective for each specific case of the disease. If the patient requires surgical intervention, the drug is prescribed after complete healing of the postoperative wound, since the active substance significantly slows down the rate of healing of mucosal tissue.

In a child under 5 years of age, the eustachian tube is shorter and wider than in an adult. Injecting a spray with a pressure dispenser device causes a funnel-shaped expansion of the mouth of the Eustachian tube, which provokes the development of tubo-otitis whenever a child has a runny nose. The medicine should be used with caution in the local treatment of allergic diseases in young children.

In addition to damaging the auditory tube, the spray under pressure enters the respiratory tract, causing irritation of the child’s pharynx and palate. Analogues of the drug in drops are not only cheaper, but also safe. Sick young children are prescribed not only local nasal, but also systemic anti-inflammatory treatment with medications, often in the form of a suspension. Suppression of inflammatory processes leads to a delay in the production of anti-inflammatory enzymes and relieves symptoms and signs of the disease.

Nasonex nasal drops physiologically descend through the nasal passages, reaching the maxillary sinus in the required quantity. If the adenoids grow, the medicine should be instilled with the head thrown back high, staying in this position for up to 5 minutes after the drug enters.

The active substance inhibits the proliferation of adenoid lymphoid tissue by reducing proliferative processes and stabilizing cell membranes.

Method of use and dosage of Nasonex with antihistamines. The drug Nasonex, which is available only in the form of a nasal spray for topical use, for persistent allergic rhinitis is prescribed along with taking medications that inhibit the production of histamine. Such combination therapy can eliminate the symptoms of eosinophilic inflammation in a short period of time.

The spray is used in adults at a daily dosage of 400 mcg, inhalations are carried out between doses of antihistamines to achieve maximum therapeutic effect. A complex local and systemic effect on the mucous membrane suppresses the formation of mast cells, stabilizes their membrane and inhibits the breakdown of arachidonic acid.

For children from two to 11 years of age, combination therapy is prescribed only after consultation with a pediatrician and allergist to identify the risk of side effects. For seasonal exacerbations, drug therapy is prescribed in a prophylactic dose a week before the expected manifestations of the disease. If the first signs of allergy appear intensely, the doctor increases the daily dosage of both drugs.