Hormonal drugs for endometriosis. How to cure endometriosis without surgery What non-hormonal pills to take for endometriosis

Endometriosis is a fairly common disease among women of childbearing age. With this pathology, the endometrium grows beyond its normal location.

The cause of this growth is most often a hormonal imbalance combined with insufficient functioning of the immune system. It is because of this that hormonal drugs for endometriosis are considered the main treatment.

Features of endometriosis

When a woman enters reproductive age, her uterus begins to experience cyclical changes associated with the activity of sex hormones. During normal functioning of the hormonal system, a balance is maintained between sex hormones. At the beginning of the cycle, estrogens predominate, which promote the growth of the endometrium and bring it to a certain thickness, and then gestagens come into play and stop its growth.

The cause of endometriosis is a disruption in this established hormone balance. Or the body begins to produce too much estrogen, which will contribute to abnormal growth of the endometrium. Either the body produces extremely few gestagens and they are not able to stop the growth of the endometrium. That is why most often the doctor prescribes hormones for endometriosis as a method of treatment.

However, despite knowing the mechanisms of development of the pathology, doctors have not yet been able to determine the exact cause of its occurrence.

There are risk factors that can increase the likelihood of endometriosis. This:

hereditary predisposition;
nutrition;
absence of children;
early puberty;
inflammatory diseases of the reproductive system;
various disorders in the menstrual cycle.

Goals of drug treatment for endometriosis

The main goal of hormonal treatment for endometriosis is to suppress estrogen concentrations. This can be achieved in several ways. Some hormonal drugs act on the ovaries, which are responsible for the production of estrogen, others on the pituitary gland, which is also involved in the production of hormones.

Since the disease endometriosis has various symptoms, drug treatment will be aimed at combating them. The gynecologist prescribes immunostimulating drugs, vitamins, painkillers and anti-inflammatory drugs.

Hormonal treatment of endometriosis should adhere to the principles of cyclicity and constant monitoring of the pathology. The fact is that such treatment does not get rid of the disease forever. And as soon as a woman stops taking hormonal medications, endometriosis returns.

Basic methods of hormonal treatment of endometriosis

The main way to treat this disease with hormonal drugs is to block the production of female sex hormones or prevent ovulation. The main methods of treatment are the following.

Imitation of pseudopregnancy. Hormonal drugs containing estrogen and progestin imitate the onset of pregnancy in the body and thus block ovulation. Progestin treatment can also be used alone, as it can cause atrophy of endometrial tissue.
Imitation of pseudomenopause. The drugs used reduce the level of sex hormones to the minimum possible value.
Blocking current ovulation. In this treatment regimen for endometriosis, drugs are used that contain a synthetically made drug, which in its properties resembles androgen - the male sex hormone. Such drugs are a good ovulation blocker, but they also have a lot of side effects.

What hormonal pills for endometriosis, as well as injections or spirals for treatment, can a doctor prescribe?

Gonadotropin-releasing hormone agonists

Natural agonists in the body are produced by the hypothalamus. They stimulate the pituitary gland to produce hormones. And a sufficient amount of these hormones reduces the production of estrogen, neutralizing the activity of the ovaries. If endometriosis is diagnosed, treatment with such hormonal drugs can compensate for the lack of gonadotropin-releasing hormone agonists in the body. From this group the following are usually prescribed:

Difelin - intramuscular injections;
Decapeptyl Depot – subcutaneous injections;
Zoladex is a subcutaneous injection into the abdominal area, which is done once a month;
Buserelin - intramuscular injections;
Lucrin-depot is a drug in the form of an injection, which is given once every 28 days.

All these medications lead the body to a state that is similar to menopause. Menstruation stops, and, consequently, the endometrium stops its development, including in places of its pathological growth.

Treatment with such hormonal injections usually lasts for six months and does not have a very good effect on the woman’s condition. She begins to fully experience all the “delights” of the onset of menopause: irritability, insomnia, dry mucous membranes, decreased libido, etc.

Also, women undergoing treatment with these drugs should take non-hormonal contraceptives. Because there is a very high risk of developing birth defects in the fetus if pregnancy occurs while taking such drugs.

Gonadotropic hormone inhibitors and antigestagens

These hormonal pills are prescribed for endometriosis to suppress follicle-stimulating hormone (FSH), luteinizing hormone (LH) and progesterone. Preparations:

Danazol and its analogs Danoval, Danol, are most often produced in the form of capsules, taken orally,
Mifepristone or Gestrinone are tablets that prevent the production of progesterone.

Hormonal medications included in this group affect the functioning of the ovaries, thereby interfering with the production of estrogen and inhibiting the growth of endometrial cells, including pathological ones.

Side effects from treatment with these medications may include weight gain, increased hair growth, and acne.

Gestagens

Hormonal treatment of endometriosis may involve the use of progesterone analogues. Such drugs will suppress the proliferation of mucous membranes:

Duphaston is a gentle remedy that is available in tablet form and taken during the menstrual cycle;
Orgametril helps prevent the appearance of new pathological lesions, and also helps reduce the size of existing ones, but is effective only in the initial stages of endometriosis;
Visanne - when taking these tablets, the growth of the endometrium first stops, then the work of the ovaries stops, and menstruation stops;
The Mirena spiral helps with mild forms of pathology; it is inserted into the uterus and, due to the presence of levonorgestrel in the composition, which begins to be released upon administration, endometrial growth is inhibited. This coil is considered an excellent treatment for uterine bleeding due to endometriosis and reduces pain.

Combined oral contraceptives

Hormonal drugs of this type for endometriosis are usually multitasking. They will protect against unplanned pregnancy, and also, due to the content of synthesized sex hormones in their composition, reduce the production of natural hormones by the body.

Thus, synthesized estrogens and gestagens help stop the growth of the endometrium. Combined oral contraceptives must be used without interruption for about six months to achieve a positive effect.

As a rule, to treat endometriosis, the doctor prescribes hormonal oral contraceptives in combination with non-steroidal anti-inflammatory drugs, the best known of which is Ibuprofen. The most commonly used medications are:

Janine;
Jess;
Yarina;
Claira;
Diana is 35;
Dimia.

While the patient takes 1 tablet per day, her menstrual flow does not begin, and her hormonal balance returns to normal. This means that estrogen will no longer have the same effect on excessive endometrial growth. But this method of treatment is only suitable for small spread of endometriosis.

It should also be remembered that the combined use of estrogen and progestin can cause side effects. The most serious side effects from taking combined oral contraceptives are increased blood pressure and the formation of thrombosis, which in turn greatly increases the risk of heart attack or stroke.

Side effects during treatment

Hormonal drugs in the form of tablets, injections and coils are good for treating endometriosis. However, before starting such treatment, all possible risks to the body should be assessed. Hormonal drugs can cause the following conditions:

liver diseases;
increased blood clotting;
decrease in the number of platelets and leukocytes in the blood;
cancerous tumors;
pathologies of the mammary glands;
cervical dysplasia;
allergic reactions.

Treatment of endometriosis with hormones allows women to feel relief within a short time. But different hormonal drugs have different effects on a woman’s body. And at the same time they have different side effects.

Therefore, before starting treatment with hormonal pills or using an IUD, you must carefully study all the risks together with your gynecologist.

Endometriosis is a disease characterized by the proliferation of endometrial cells outside the inner layer of the uterine wall. With endometriosis of the uterus, endometrioid lesions lead to inflammation of adjacent tissues, resulting in the development of adhesions, scars and cystic neoplasms. To suppress foci of the disease, the doctor selects hormonal pills for uterine endometriosis.

The essence of hormonal treatment for endometriosis

The goal of hormone therapy for endometriosis is to stop the growth and reduce endometrioid pathological growths by suppressing the production of estrogen. Some hormonal drugs for endometriosis affect the ovaries, which are responsible for the production of estrogen, while others affect the pituitary gland, which takes part in the production of hormones. Hormonal therapy is carried out in long courses.

There are 3 ways to treat the disease:

Imitation of pregnancy. Combined hormonal medications are taken, which contain estrogen and progestin, which simulate the onset of pregnancy in the body, blocking ovulation. Progestin can also be used separately, since it leads to a reduction in the size of endometrial tissue.
Simulating menopause. Hormonal medications are prescribed to help reduce the level of sex hormones to a minimum concentration.
Suppression of ongoing ovulation. To do this, the doctor prescribes medications containing synthetic androgen, which is a natural sex hormone in men. These medications are excellent at blocking ovulation, but have many side effects.

GnRH agonists

GnRH agonists restore the connection between the pituitary gland, hypothalamus and ovaries in women suffering from endometriosis.

When treating with this group of drugs the following is observed:

development of artificial menopause;
loss of sensitivity of pituitary cells;
decreased release of gonadotropin compounds.

These effects occur because gonadotropin binds to GnRH receptors located in the adenohypophysis. With regular administration of medications, the release of gonadotropin stops. This causes absence of menstruation.

Progestogens

Progestogens are a class of steroid hormones that bind to and activate the progesterone receptor. Drugs in this group cause a decidual reaction and help reduce the growth of endometrial tissue.

Gonadotropic hormone inhibitors and antigestagens

Such hormonal pills are prescribed when diagnosing endometriosis to suppress FSH, LH and progesterone. Inhibitors of gonadotropic hormones and antigestagens affect the functioning of the ovaries, blocking the production of estrogen and stopping the growth of pathological endometrial cells.

Pharmacy drugs

Pharmacies sell a large number of hormonal drugs for the treatment of endometriosis.

Zoladex (Goserelin)

Active ingredient of the drug: goserelin acetate. Goserelin is a synthetic analogue of natural gonadotropin-releasing hormone. When taken regularly, the medication inhibits the pituitary gland's release of luteinizing hormone, reducing the concentration of estradiol in the blood in women. During the treatment of endometriosis, the drug helps reduce pain, the size and number of endometrioid lesions. The medication in an amount of 3.6 mg is injected into the shoulder or abdomen every 28 days. The course of treatment lasts for six months.

Buserelin

The drug normalizes hormonal balance, causing thinning of the endometrium. The active ingredient of the drug is buserelin acetate. The drug is available in the form of a nasal spray and solution for injection.

With regular use of the medicine, the production of the hormone estrogen ceases. The effectiveness of the drug appears after 2-3 months of treatment. In most cases, the duration of the treatment course is 6 months.

The daily dose of nasal spray is 900 mcg. The dosage of 1 injection depends on the patient’s body weight. The course of therapy consists of 6 injections, which are administered once every 4 weeks.

Diferelin

The active component of the long-acting medication is triptorelin acetate. The drug suppresses ovarian function.

When used regularly, the drug provokes the onset of artificial menopause in women. In parallel with the central action, the drug affects peripheral receptors, helping to reduce their sensitivity to the factor that is responsible for the release of gonadotropin.

In the presence of endometriosis, the dosage is 3.75 mg every 28 days. The injection should be administered in the first 5 days from the start of the menstrual cycle. Therapy for the disease can last up to 6 months.

Utrozhestan and Duphaston

The active component of Duphaston is dydrogesterone, which is a progestogen that is effective when taken orally. The active component of Utrozhestan is progesterone. These medications fully ensure the onset of the secretion phase in the endometrium, reducing the risk of developing hyperplasia.

In recent years, endometriosis has become one of the most common gynecological diseases. Today, it is diagnosed in every tenth woman of reproductive age, but most often after 35 years. This article will discuss the main drugs for the treatment of endometriosis in women, and we will also study the degree of their effectiveness in this disease.

General information about the disease

Endometriosis is a gynecological disease characterized by the proliferation of the inner glandular layer of the uterus (endometrium). Fragments of epithelial tissue can grow into the ovaries, tubes, bladder, peritoneum and rectum. Endometrioid lesions are hormone-dependent in nature, so they are subject to cyclic changes characteristic of the phases of the menstrual cycle.

The growth of the endometrium provokes attacks of pain and enlargement of the affected organ. Due to the growth of the inner uterine layer, monthly bleeding may intensify and lengthen, and secretions from the mammary glands appear.

Gonadotropin-releasing hormone agonists

Naturally occurring agonists are produced in the hypothalamus and promote the release of hormones by the pituitary gland. And they, in turn, in large doses can neutralize the activity of the ovaries, which means they can reduce the level of estrogen. Medicines containing GnRH agonists can solve this problem, these include:

Diferelin. It is administered intramuscularly from days 1 to 5 of the cycle, the course is repeated after 28-30 days;
Decapeptyl Depot. It is necessary to administer 3.75 mg subcutaneously from days 1 to 5 of the cycle, repeat the course after 28-30 days;
Zoladex. Subcutaneous injection in the abdominal area. The release of the active substance by the drug lasts 28 days. The course is repeated in the next cycle;
Buserelin. Used as intramuscular injections of 3.75 mg once a month, during the first 5 days of the cycle;
Lucrin depot. Injections are given during the first three days of the cycle. Treatment is repeated after a month.

Such drugs help to stop the development of not only foci of growth, but also the entire endometrium; the woman is put into a state of artificial menopause when she does not have menstruation. This treatment lasts about six months.

This is a difficult time, during which other signs of menopause may appear: irritability, sleep problems, decreased sex drive. Bone density may decrease and the likelihood of bone damage increases.

Gonadotropic hormone inhibitors and antigestagens

Inhibitors used to treat endometriosis suppress the production of FSH, LH and progesterone. These include:

Danazol based on testosterone. Must be taken orally, available in capsule form. The dosage is selected by the doctor, but not more than 800 mg per day. Analogs Danoval and Danol;
Mifepristone, Gestrinone. These medications suppress the production of progesterone and estrogen and cause anovulation. Prescribed individually, but not more than 0.2 g per day.

These drugs inhibit the development of cells in the inner mucous layer of the uterus, including those that develop outside the reproductive organ.

Gestagens

Hormone therapy includes drugs based on artificial progesterone, which suppresses the development of endometrial cells. This type of medicine includes:

Duphaston. Available in tablets, drink from 5 to 25 days of the cycle, several courses in a row;
Byzanne. Take 1 tablet per day;
Orgametril. These tablets prevent the development of new foci of the disease and reduce the size of existing ones. Take 1 tablet every day from the 14th to the 25th day of the cycle. For severe bleeding, the dose can be doubled.

Contraception for endometriosis

Hormonal oral contraceptives can simultaneously perform several functions: firstly, they are used to increase the concentration of estrogens and gestagens in the body in the treatment of endometriosis, and also as birth control pills.

Let's list what contraceptive medications are prescribed for the growth of the inner layer of the uterus:

Diana is 35;
Janine;
Jess;
Yarina;
Dimia et al.

The effect will be noticeable only after continuous use of these funds for 3-6 months.

Non-hormonal drugs

Non-hormonal treatment will be aimed at eliminating the accompanying symptoms of endometriosis. To eliminate the feeling of heaviness and relieve the inflammatory process, drugs such as Ibufen, Papaverine or Novigan may be prescribed. Cycloferon, Ascorbic acid, Tocopherol, Pyridoxine, etc. will help improve overall well-being and boost immunity.

Another popular remedy that can relieve pain and relieve inflammation, as well as reduce endometriotic lesions without hormones, is Endoferin. The course of treatment takes 90 days and is divided into 3 periods.

Only a specialist can treat with non-hormonal and hormonal drugs.

Antibacterial drugs

Antibiotics for endometriosis are prescribed only when the disease is accompanied by inflammation and the development of infection. Broad-spectrum antibacterial drugs are usually prescribed: Doxycycline, Tienam, Penicillin, Macrolide. Additionally, droppers with drugs from the cephalosporin group (Cedex, Ceftazidime, etc.) can be placed.

In advanced stages of the disease, antifungal antibiotics are prescribed(Nystatin, Mikosist, Flucostat), but this only happens when the patient paid too little attention to the prevention of complications.

What candles can be used

If a large number of analgesics are contraindicated for the patient, then suppositories with an analgesic effect can be prescribed for endometriosis. The most effective non-steroidal anti-inflammatory suppositories for this disease are Diclofenac, Indomethacin. They relieve pain quickly and for a long time.

Not every remedy in the form of suppositories is administered intravaginally for endometriosis; there are medications that are prescribed for rectal use:

Flamax based on ketoprofen. Apply once a week;
Diclofenac. Use 1 suppository every day;
Voltaren. A strong painkiller that is used 2 times a day;
Movalis. Use a candle at night, no more than a week;
Indomethacin. Use every day at night.

The dosage and combination of drugs in the treatment of endometriosis can be selected exclusively by the attending physician.

First, let's figure out what it is. Normally, menstruation is a consequence of the rejection of the functional layer of the inner wall of the uterus (endometrium). With the development of endometriosis, areas with cells of this functional layer are formed in various organs and systems, performing the same function; these cells grow and are rejected, that is, they “menstruate”.

Endometriosis is a chronic disease that occurs mainly before the age of 40. With age, the risk of developing pathology decreases.

The reasons for the development of endometriosis can be different:

reflux of blood during menstruation and cells of the inner layer of the uterus into the abdominal cavity, but for this there must be certain conditions;
increased amounts of some and decreased amounts of other hormones;
disorders in the immune system (autoimmune reaction);
development from cells that in the embryonic period were supposed to participate in the formation of genital organs;
manipulations that promote displacement of the endometrium into the uterine wall and the development of adenomyosis (abortion, curettage, cesarean section, etc.);
cells can spread throughout the body through the lymph and blood, which leads to the development of endometriosis in other systems.

More often, especially in the initial stages, a woman is not aware of the disease. Later, complaints appear that vary depending on the localization of the process:

with endometriosis of the uterus, heavy, prolonged menstruation and/or bleeding in the middle of the cycle are disturbing, which leads to severe anemia;
with endometriosis of the cervix, spotting occurs during sexual intercourse or on the eve of menstruation;
if the fallopian tubes, ovaries or pelvic peritoneum are affected, then pelvic pain occurs, intensifying during menstruation and sexual intercourse;

From other organs and systems, the clinical picture will depend on the location of the lesion:

with endometriosis of the lungs, hemoptysis appears;
when localized in the urinary system and intestines, discharge from the bladder and rectum will be disturbing; bleeding of surgical scars.

OK for endometriosis: contraception or treatment?

Endometriosis requires mandatory treatment, which can be:

medicinal;
surgical;

The choice of treatment method is decided individually and depends on many factors, including the location of endometriosis. An important element in treating the disease is taking oral contraceptives.

OCs for the treatment of endometriosis can be used both before and after surgical treatment. For example, if endometriosis is localized outside the uterus, surgical treatment is first performed, and only after (in the postoperative period) hormonal therapy is prescribed to avoid relapse. For endometriosis of the uterus (adenomyosis), hormones are prescribed in the initial stages, and in severe cases, the uterus is removed.

Treatment of endometriosis with COCs does not replace surgery, but stops the functioning and spread of altered areas due to the development of atrophic processes in them. There are several groups of hormonal drugs, among which there is a group of OCs, which, along with a therapeutic effect, have a contraceptive effect.

Which OCs are best for endometriosis?

Combined contraceptives act on the endometrium, inhibit cell division and reduce the release of gonadotropins by the pituitary gland, which provides a therapeutic effect. Accordingly, endometriosis inhibits its development when taking OCs. However, OK, like any other drug, has its side effects and contraindications, so only a doctor can prescribe a drug of this profile after studying the patient’s medical history.

Since OCs for endometriosis are taken continuously and for a long time (for 6-12 months), it is important to promptly identify contraindications and assess all possible risks. If necessary, you can replace OK with a drug from another group.

In the treatment of endometriosis, monophasic COCs with a low dose of ethinyl estradiol are used, where the following are preferred as gestagens:

janine, silhouette (e/e 0.03 mg + dienogest 2 mg);
rigevidon (e/e 0.03 mg + levonorgestrel 0.15 mg);
logest (e/e 0.02 mg); Lindinet 30, femodene (e/e 0.03 mg) + gestodene 0.075 mg;
Novinet (e/e 0.02 mg), Regulon, Marvelon (e/e 0.03 mg) + desogestrel 0.15 mg.

In monophasic COCs, estrogen and progestogen are contained in the same dosages in all tablets. In two-phase preparations there are two types of tablets with different doses, in three-phase preparations there are three types of tablets.

Depending on the amount of estrogen in the drug, contraceptives are divided into:

high-dose - 0.05 mg/day;
low-dose - 0.03 - 0.035 mg/day;
microdosed - 0.015 - 0.02 mg/day.

Endometriosis after 35 and 40: which COC to choose?

Age after 35 years is a relative contraindication to the use of COCs, as there is a risk of thrombosis, especially in the presence of other risk factors (smoking, obesity, diabetes, arterial hypertension).

If there are contraindications, it is better to prefer another group of hormonal drugs. If there is no health risk for a particular patient, then low-dose monophasic drugs are chosen for the treatment of endometriosis.

OK "Siluet" for endometriosis

The drug Siluet is a monophasic drug - 21 tablets contain ethinyl estradiol (0.03) and dienogest (2) mg. OK "Siluet" is an analogue of the well-known drug "Zhanin" with a slight difference in the excipients.

The condition of a patient with endometriosis improves after taking OC, since OC prevents the recurrence of the pathological lesion, relieves pain, and reduces the duration and volume of bleeding. After a course of therapy, a woman’s reproductive system begins to function normally and the likelihood of conception increases.

Vladlena Razmeritsa, obstetrician-gynecologist, especially for the site

Useful video

Women who are faced with a uterine disease called endometriosis resort to the use of various treatment methods. One of the most famous is the use of birth control pills for endometriosis, if prescribed by a gynecologist.

The pathology is not treated only with the use of contraceptives, but pills improve the general condition of the body, menstruation becomes less painful, and the development of the endometrium is delayed. Patients who have undergone treatment using hormonal contraceptives speak well of the effect obtained.

The echostructure tissue inside the uterus, formed on its walls, grows and extends beyond its limits, is called endometriosis. Gynecologists do not know the exact cause, but it is known that the appearance of pathology is influenced by negative factors: intrauterine, adnexal infections, disruptions in the woman’s hormonal levels, disruption of the ovarian follicles. The disease is transmitted through the mother's hereditary line.

Women of reproductive age who have had problems with the body, the genitals in particular, are susceptible to developing the disease. The appearance of endometriosis is affected by abortion, pregnancy, irregularities in the menstrual cycle, and diseases associated with the ovaries. When thyroid disorders occur, hormonal imbalances occur, which leads to endometriosis.

Abnormal growth of the endometrium inside the uterus, ovaries, fallopian tubes, lungs is eliminated with the help of medications.

The area of layers of endometrial cells inside the main reproductive organ grows during the first half of the menstrual cycle. About 5-10% of the female population suffer from pathology caused by various reasons, the main one of which is changes in hormonal levels. An egg that has not undergone fertilization does not attach to the intrauterine walls, and the endometrium begins to peel off. The layer that has not completely come out remains inside, attached to places unusual for it.

Doctors carry out diagnostics using intravaginal ultrasound and examine the abdominal and pelvic organs. In some cases, the disease is detected during examination by a gynecologist. The disease and its symptoms do not go away on their own; it is necessary to use a surgical or medicinal, and sometimes a combined approach to treatment. The earlier the disease is diagnosed, the greater the chances for a speedy recovery.

Surgical intervention allows you to eliminate the endometrium through abdominal surgery, laparoscopy, or omentectomy.

After the examination, the doctor selects the optimal treatment option, based on the degree of development, so that the patient’s illness stops and she feels better. When prescribing medications and using them in accordance with the instructions and prescriptions of the doctor, it starts the process of splitting the echostructure if the woman has the initial stage of the disease. Medicines eliminate inflammatory processes.

Among the patients using medication, there are many who got rid of the initial stage of the disease and also restored some body functions. You won’t be able to choose pills that treat an illness on your own; they are selected individually. Hormonal-based contraceptives not only protect against unwanted pregnancy, but also have a positive effect, containing the necessary dose of estrogen hormones, which a woman’s body needs in the fight against endometriosis.

Symptoms

The initial stage does not manifest symptoms, the woman does not experience discomfort. Over time, when the disease progresses to the next, more severe stage, the body’s functioning and the woman’s well-being sharply deteriorate. During menstruation and during normal times, symptoms appear as follows:

The woman experiences heaviness, aching pain in the lower abdomen;
Pain in the lower abdomen appears and disappears;
Serous and bloody vaginal discharge is observed;
Menstruation becomes more painful, the number of days is either greatly reduced or significantly increased;
During bowel movements, painful sensations of a pressing type appear;
Unpleasant sensations during urination.

Women experiencing any manifestation of symptoms should immediately consult a doctor to prevent the development of the disease.

Consequences

Endometriosis is considered a benign disease, but the lack of proper treatment leads to negative consequences, including infertility:

A woman's chances of becoming pregnant decrease sharply. The embryo will not be able to attach itself to an overgrown benign formation;
Miscarriages and spontaneous abortions occur. The fetus is rejected by the tumor area, which in a healthy state is a nutrient medium. A miscarriage occurs or the embryo lags behind in development;
When a woman becomes pregnant, the baby begins to grow, and the tumor also increases in volume, filling the space with itself. The fetus is in cramped conditions, uncomfortable, does not receive enough nutrients, which affects the occurrence of deformities on the body.

Combined oral contraceptives improve the general condition of the body, improve weight, and relieve skin problems in the form of acne and pimples only after a full examination by a doctor. By making independent choice and application, a woman exposes herself to danger, triggering irreversible processes. The choice of tablets depends on age, stage of the disease, and other things.

Antiprogestins. These include the drugs Mifepristone and Danazol. They have a suppressive effect, eliminating the production of female hormones. Menstruation stops, but the process can later be restored. Effective, but have disadvantages:

The mammary glands become smaller;
Hair appears in places uncharacteristic for women;
Weight increases (85% of patients experience this problem).

Gonadotropin-releasing hormone agonists. The most commonly used drug is Buserilin, which causes a condition in the body similar to menopause. It has good efficacy rates, but when used for more than three months, it leads to osteoporosis. Prescribing such drugs does not completely cure, but “preserves” the disease so that the body of the expectant mother can prepare for pregnancy, gestation and childbirth. Prescribed in cases of contraindications for surgical intervention.

Endometriosis reduces the rate of development or stops growing altogether;
Helps avoid unwanted pregnancy;
Has an affordable price;
Minimal list of side effects;
No discomfort during sex;
Possible improvement in the condition of the skin, hair, correction of body weight;
Easy to use.

Contraindications:

When growing outside the uterine area;
Presence of diabetes, diseases of the endocrine system;
Kidney, liver diseases;
Thrombosis, vascular disease, heart disease, hypertension;
Pregnancy and lactation period.