Klion d tablets during menstruation. Klion d - instructions for use, side effects, analogues, reviews, price

Treatment of inflammatory diseases of the female genital area requires consistency and regularity. Natural temporary problems of the body of the fair sex should not interfere with the therapy.

Menstruation quite often becomes an obstacle to treatment. Experts disagree on whether the drug “Klion D” can be used during menstruation. To use this drug correctly, you should know the capabilities of the recommended drug, its positive and negative sides.

This medicine is presented on the pharmacy market in a single form - vaginal tablets, so their effect is mainly of a local nature. The drug contains two known components:

  • First of all, we are talking about miconazole. This substance is a derivative of ergosterol or a mixture of fatty complexes of protozoan fungal cells. Due to its functions, the compound in question promotes the entry of large amounts of ordinary table salt and minerals into the cells of Candida fungi, which leads to their death. Miconazole is used to combat various fungal pathologies.
  • The second active component of this drug is metronidazole. This medicinal substance is widely used for various bacterial problems in many aspects of medicine. Metronidazole is used by surgeons, obstetricians-gynecologists, urologists and other doctors dealing with various infections. Its main function is to ensure the restoration of cells damaged by various harmful microorganisms.

After conducting numerous experiments, it turned out that these two substances complement each other perfectly. Therefore, the drug “Klion D” has become quite widespread among dermatologists and gynecologists.

The drug allows you to simultaneously provide assistance to women suffering from trichomoniasis and other inflammatory diseases of the vagina and internal genital organs.

The literature describes the use of KlionD during menstruation, but data on the results and consequences vary greatly.

Watch the video about the action of the drug:

Use of the drug for various diseases

The method of using vaginal tablets “Klion D” has several features. The thing is that suppositories require additional moisture, so right before administering the drug inside a woman, it is advisable to douche with warm water. A soap solution of weak consistency is also possible.

For trichomoniasis

The process of introducing the medicine into the patient’s vagina takes several minutes before the patient falls asleep. Most often, a woman needs 10 to 12 days for a complete recovery. However, quite often visible successes are not confirmed. In this case, you have to take 2 tablets of the drug “Metronidazole” daily, 2 times a day per os (by mouth) 40 minutes before meals.

Treatment of thrush

Up to 30% of the female population of the world suffers from candidiasis or thrush at different times of life, and it should be noted that menstrual bleeding is quite often a stimulating factor. Therefore, the question of whether “Klion D” can be taken during menstruation is especially relevant for this disease.

It should be noted that when treating thrush, this drug is used daily for 12 to 14 days. The tablets require the same amount of moisture as in the treatment of trichomoniasis. The moment of administration of the drug is also not original: the medicine is best taken 15 - 20 minutes before bedtime in a supine position.

Doctors note that the course of taking the drug “Klion D” can be repeated several times until the result is obtained, however, in this case, laboratory monitoring of treatment is also required. According to the annotation, the medicine is able to resist all fungi of the Candida family, however, there are exceptions to any rule.

Special conditions for drug treatment

When using “Klion D” to treat trichomonas or fungi, a woman should be aware of some specific requirements and conditions:

  • First of all, you should remember that this drug affects the human nervous system and can cause depression of attention, drowsiness, and apathy. If taking the drug provoked such a reaction, it is contraindicated to drive a car or work in precision and high-speed production, such as a conveyor belt.
  • “Klion D” can provoke increased transmission of pathogens of trichomoniasis and candidiasis to sexual partners. This occurs due to the aggressive effect of the drug on the female flora. It is recommended to stop all sexual intercourse for the duration of treatment.
  • Since the drug contains metronidazole, under its influence it is possible to change the blood formula of a sick woman: during the analysis, leukopenia is present or up to 50% below normal. Such a symptom may also indicate the development of disorders in the patient’s immune system.

And, of course, as with any medication, young ladies will be concerned about a possible overdose when taking the drug. If only vaginal tablets are used, then the question of overdose or poisoning does not even arise.

Side effects are possible only with the simultaneous use of Klion D and Metronidazole tablets. In this case, it is quite rare, but various manifestations from the gastrointestinal tract are possible, which can be relieved by stopping the drug and using activated charcoal along with gastric lavage. More severe symptoms require the intervention of acute poisoning specialists.

“Klion D” and menstruation

As mentioned above, this drug is used for female diseases that may respond to interrupted treatment with a negative result of therapy and regression of the disease. What to do if, during the height of the drug fight against thrush or trichomonas, the patient began to have monthly bleeding?

“Klion D” suppositories can be used during menstruation, since they do not cause a significant effect on the patient’s hormonal levels and do not affect the patient’s blood coagulation system. However, the strength of their effect on the microflora will be 2-3 times less, since the medicinal substance introduced into the woman’s body can be washed out with the bloodstream from the vagina.

In addition, the therapeutic effect of the constituent substance miconazole will also be reduced during this period; the antifungal component interacts with blood fractions and can decompose. At the same time, the medical literature does not describe pathological reactions to the use of the drug “Klion D” during menstruation.

The same can be said regarding the use of the medicine for women “Klion D 100” during menstruation. You should not expect negative reactions to the drug, since this name is simply a brand name for regular vaginal tablets. However, the effect of treatment will be much lower than usual.

Based on all of the above, we can conclude: the use of the drug “Klion D” during menstruation is not dangerous, it’s just that the treatment requirements in this case should be significantly reduced. If possible, the course of therapy with the drug in question should be carried out during the normal period of the woman’s condition, however, sudden monthly bleeding is not an excuse to stop treatment.

The use of any drugs to combat infections of the female genital area can only be carried out under the supervision of specialists. It is gynecologists and dermatologists who are obliged to educate the patient in all the intricacies of treatment of the identified female genital pathology, give appropriate recommendations, and explain the possibility and problems of undergoing specific therapy on critical days.

What are Klion D candles?

This drug contains a substance called metronidazole. It is very quickly absorbed into the blood, penetrates into breast milk, and through the placenta reaches the fetus in pregnant women; it also penetrates the spinal cord and brain. About 60 to 80% of the substance is excreted from the body by the kidneys during urination, and the urine may be reddish or brown in color. The remaining 20 to 40% are excreted from the body in feces through the intestines. Another substance in the drug that also has an active effect on the body is miconazole, but it is almost not absorbed into the blood and remains in the body for a long time.

The big advantage of this drug is that the substances contained in this drug act selectively, they destroy only pathogenic microorganisms, while beneficial bacteria remain unharmed, the composition of the microflora and acidity of the vagina does not change.

  1. Candida fungi;
  2. Trichomonas vaginalis;
  3. Vaginal amoeba;
  4. Gardnerella;
  5. Guardia;
  6. Bacteroides;
  7. Fusobacteria;
  8. Vilonella;
  9. Prevotella;
  10. Clostridia;
  11. Eubacteria;
  12. Peptococci;
  13. Peptostreptococci.

How to use the drug?

Klion D suppositories must be inserted deep into the vagina; this is done using a finger. Before starting the procedure, you must thoroughly wash your hands and also wash your external genitalia using warm water and soap. Just before insertion into the vagina, the tablet must be wetted, the water must be clean and warm. It is necessary to administer 1 tablet per day, it is better to do this in the evening, just before bedtime. The course of treatment is 10 days. To increase the effectiveness of treatment, it is better to accompany local therapy with these vaginal tablets by taking one tablet orally in the morning and evening Klion or Metronidazole, also for 10 days. It is recommended to take the tablets orally during or after meals; under no circumstances should you chew the tablets; you must swallow them whole.

If a course of treatment of 10 days does not produce results, it is necessary to extend it for another 10 days. Treatment is necessary not only for the woman herself, but also for her sexual partner. He also needs to take metronidazole tablets by mouth. If there is a need for several courses of treatment in a row, then you can repeat it as many times as necessary. But still, if it happens that Klion D suppositories did not help after two courses of treatment, then you need to consult a doctor to do research on the sensitivity of the fungus that caused the disease to the drug. Perhaps in this case the disease needs to be treated with another drug.

Klion D during pregnancy

For up to twelve weeks, the use of Klion D suppositories is contraindicated, since metronidazole, which is included in its composition, is absorbed into the blood and penetrates through the placenta to the fetus. You can use the drug from the thirteenth to the fortieth week of pregnancy, but if possible, it is better to avoid it. It should be used only after all possible risks and all intended therapeutic effects have been weighed. Although there is no exact information about whether the drug is harmful to the unborn child. The experiments were carried out only on mice; experiments have not been carried out on pregnant women and are unlikely to ever be carried out. As a result of the experiments, it was revealed that if pregnant rats and mice were administered the drug and the dosage was appropriate to their bodies, then no negative effect on the fetus was detected, but when mice and rats were administered a dose of the drug such as that received by humans, it was found that the drug has a toxic effect on the fetus.

Klion D during menstruation

Doctors do not recommend using this method of therapy during menstruation, since, firstly, blood in the genital tract and organs greatly reduces the effectiveness of the active ingredients of this vaginal drug. Secondly, during menstruation, particles of the dissolved tablet also come out of the vagina with menstrual blood. It turns out that the required amount of active substances, which are aimed at destroying pathogens, decreases and becomes insufficient to fight the disease, therefore, treatment becomes ineffective. Therefore, if a woman has her period, then she should not start using the pills; it is better to wait until her period ends and continue the course of treatment after the end of menstrual bleeding. If during the course of treatment your periods unexpectedly begin, you can either refuse treatment and continue it later, or continue to use vaginal tablets, but you should remember that the treatment will not be effective enough.

Regimen during the course of treatment

It is necessary to observe a regime of refusal of any sexual contacts with any partners during the entire course of treatment. If it is impossible to completely refuse sexual relations due to taking Klion D, then it is necessary to use a condom during sex.

You should not drink alcoholic beverages during the course of treatment, as alcohol affects consciousness, the liver, muscles and coordination of movements, so alcohol can cause side effects - nausea, vomiting, dizziness, redness of the skin.

Side effects

If only the vaginal version of the drug is used without concomitant drug therapy, then an overdose is impossible. If it is used in combination with tablets for oral administration, then in case of an overdose various side effects may occur: diarrhea, vomiting, nausea, abdominal pain, itching on the skin, a metallic taste in the mouth, coordination of movements (ataxia), dizziness, convulsions, red urine, crawling sensations on the skin.

If the symptoms of an overdose are obvious, then an urgent gastric lavage is necessary, then you should take activated charcoal, polyphepane, and in case of severe intoxication of the body you will even have to undergo a hemodialysis procedure. Next, you need to act according to the situation, that is, based on what side effects are observed, these effects should be treated specifically.

In addition, women using this drug may experience adverse reactions such as unusual discharge from the external genitalia, itching and burning of the genital mucosa, and a feeling of discomfort. The discharge is most often mucous, transparent or white, with a slight odor. Sometimes the discharge is thick, with white flakes and an almost imperceptible odor. Some women may have orange, brownish or red discharge, which is caused by blood. Discharge mixed with blood is the result of the fact that the vessels located in the vaginal mucosa are injured, and they are injured due to inflammation. Even if such discharge occurs, there is no need to stop treatment, just as there is no need to visit a gynecologist. Discharge may continue for two weeks after use of the drug is stopped. Discharge, such as sensations of itching, burning, pain inside the vagina, is a normal phenomenon, do not be afraid of them. These symptoms can occur at any time during the course of treatment, for some on the first day, for others only on the fifth day - this is an individual characteristic of the body to react to the use of substances included in this drug.

Who is the drug contraindicated for?

Use of Klion D during menstruation

Every girl who has reached puberty knows that about once a month there comes a period when you just want to climb the wall, because you cannot understand your body. First of all, you must understand that everything that happens to you is absolutely normal. Your mood changes in a second, you want to eat, you feel nauseous, your legs and back hurt, and at the same time someone may not be able to sit still. And all this happens because our body and organism become many times more sensitive.

What are Klion D candles?

Klion D suppositories are a local drug. With its help, women are treated for genital infections, in particular trichomoniasis and candidiasis. This drug is available in the form of vaginal tablets that must be inserted into the vagina. Fights microorganisms that cause disease. Antibacterial and antifungal candles. This medicine is produced by the world famous Hungarian pharmaceutical company GEDEON RICHTER. In pharmacies, Klion D suppositories are sold in packages containing 10 oval, white tablets with a pointed end, on one side of which there is an engraving “100”.

This drug contains a substance called metronidazole. It is very quickly absorbed into the blood, penetrates into breast milk, and through the placenta reaches the fetus in pregnant women; it also penetrates the spinal cord and brain. About 60 to 80% of the substance is eliminated from the body by the kidneys during urination, and the urine may be reddish or brown in color. The remaining 20 to 40% are excreted from the body in feces through the intestines. Another substance in the drug that also has an active effect on the body is miconazole, but it is almost not absorbed into the blood and remains in the body for a long time.

How does Klion D work?

When its substances enter the body, they have a suppressive effect on the synthesis of microbial DNA, for this reason, reproduction for microorganisms becomes impossible; microorganisms that have already managed to reproduce die due to the fact that under the influence of the substances, fungal cells become permeable to water and salts that enter the cell upset its balance.

The big advantage of this drug is that the substances contained in this drug act selectively, they destroy only pathogenic microorganisms, while beneficial bacteria remain unharmed, the composition of the microflora and acidity of the vagina does not change.

Pathogenic microorganisms that die under the influence of this medicine:

  1. Candida fungi;
  2. Trichomonas vaginalis;
  3. Vaginal amoeba;
  4. Gardnerella;
  5. Guardia;
  6. Bacteroides;
  7. Fusobacteria;
  8. Vilonella;
  9. Prevotella;
  10. Clostridia;
  11. Eubacteria;
  12. Peptococci;
  13. Peptostreptococci.

How to use the drug?

Klion D suppositories must be inserted deep into the vagina; this is done using a finger. Before starting the procedure, you must thoroughly wash your hands and also wash your external genitalia using warm water and soap. Just before insertion into the vagina, the tablet must be wetted, the water must be clean and warm. It is necessary to administer 1 tablet per day, it is better to do this in the evening, just before bedtime. The course of treatment is 10 days. To increase the effectiveness of treatment, it is better to accompany local therapy with these vaginal tablets by taking one tablet orally in the morning and evening Klion or Metronidazole, also for 10 days. It is recommended to take the tablets orally during or after meals; under no circumstances should you chew the tablets; you must swallow them whole.

If a course of treatment of 10 days does not produce results, it is necessary to extend it for another 10 days. Treatment is necessary not only for the woman herself, but also for her sexual partner. He also needs to take metronidazole tablets by mouth. If there is a need for several courses of treatment in a row, then you can repeat it as many times as necessary. But still, if it happens that Klion D suppositories did not help after two courses of treatment, then you need to consult a doctor to do research on the sensitivity of the fungus that caused the disease to the drug. Perhaps in this case the disease needs to be treated with another drug.

Klion D during pregnancy

For up to twelve weeks, the use of Klion D suppositories is contraindicated, since metronidazole, which is included in its composition, is absorbed into the blood and penetrates through the placenta to the fetus. You can use the drug from the thirteenth to the fortieth week of pregnancy, but if possible, it is better to avoid it. It should be used only after all possible risks and all intended therapeutic effects have been weighed. Although there is no exact information about whether the drug is harmful to the unborn child. The experiments were carried out only on mice; experiments have not been carried out on pregnant women and are unlikely to ever be carried out. As a result of the experiments, it was revealed that if pregnant rats and mice were administered the drug and the dosage was appropriate to their bodies, then no negative effect on the fetus was detected, but when mice and rats were administered a dose of the drug such as that received by humans, it was found that the drug has a toxic effect on the fetus.

Klion D during breastfeeding?

Doctors unanimously say that under no circumstances should you combine breastfeeding with the use of this medication. Why? Yes, for the reason that the substances that Klion D vaginal suppositories contain penetrate into the blood, and from the blood into breast milk, and with milk these substances enter the child’s body. This leads to the conclusion that the drug should not be taken simultaneously with breastfeeding. If the use of tablets during this period cannot be avoided, then it is better to stop breastfeeding the baby while the mother is undergoing treatment. After the course of treatment has been completed, two days after using the last vaginal tablet, you can resume breastfeeding.

Klion D during menstruation

Doctors do not recommend using this method of therapy during menstruation, since, firstly, blood in the genital tract and organs greatly reduces the effectiveness of the active ingredients of this vaginal drug. Secondly, during menstruation, particles of the dissolved tablet also come out of the vagina with menstrual blood. It turns out that the required amount of active substances, which are aimed at destroying pathogens, decreases and becomes insufficient to fight the disease, therefore, treatment becomes ineffective. Therefore, if a woman has her period, then she should not start using the pills; it is better to wait until her period ends and continue the course of treatment after the end of menstrual bleeding. If during the course of treatment your periods unexpectedly begin, you can either refuse treatment and continue it later, or continue to use vaginal tablets, but you should remember that the treatment will not be effective enough.

Regimen during the course of treatment

It is necessary to observe a regime of refusal of any sexual contacts with any partners during the entire course of treatment. If it is impossible to completely refuse sexual relations due to taking Klion D, then it is necessary to use a condom during sex.

When using this drug, it is strictly not recommended to test for treponemes, since the substances contained in this medicine will cause incorrect test readings.

While using this drug, a decrease in the number of leukocytes in the blood may occur; for this reason, while using these vaginal tablets, it is necessary to periodically take blood tests.

Combination of Klion D with other medications

The use of Klion D can be combined in parallel with antibiotics and sulfa drugs, regardless of the method of taking them - injections or tablets.

You should not drink alcoholic beverages during the course of treatment, as alcohol affects consciousness, the liver, muscles and coordination of movements, so alcohol can cause side effects - nausea, vomiting, dizziness, redness of the skin.

Side effects

Attention disturbances may occur as the drug affects the nervous system. While taking the drug, you should avoid any activities that require good reaction, concentration, and attentiveness, for example, you should not drive a car, or perform work on an assembly line, etc.

If only the vaginal version of the drug is used without concomitant drug therapy, then an overdose is impossible. If it is used in combination with tablets for oral administration, then in case of an overdose various side effects may occur: diarrhea, vomiting, nausea, abdominal pain, itching on the skin, a metallic taste in the mouth, coordination of movements (ataxia), dizziness, convulsions, red urine, crawling sensations on the skin.

If the symptoms of an overdose are obvious, then an urgent gastric lavage is necessary, then you should take activated charcoal, polyphepane, and in case of severe intoxication of the body you will even have to undergo a hemodialysis procedure. Next, you need to act according to the situation, that is, based on what side effects are observed, these effects should be treated specifically.

In addition, women using this drug may experience adverse reactions such as unusual discharge from the external genitalia, itching and burning of the genital mucosa, and a feeling of discomfort. The discharge is most often mucous, transparent or white, with a slight odor. Sometimes the discharge is thick, with white flakes and an almost imperceptible odor. Some women may have orange, brownish or red discharge, which is caused by blood. Discharge mixed with blood is the result of the fact that the vessels located in the vaginal mucosa are injured, and they are injured due to inflammation. Even if such discharge occurs, there is no need to stop treatment, just as there is no need to visit a gynecologist. Discharge may continue for two weeks after use of the drug is stopped. Discharge, such as sensations of itching, burning, pain inside the vagina, is a normal phenomenon, do not be afraid of them. These symptoms can occur at any time during the course of treatment, for some on the first day, for others only on the fifth day - this is an individual characteristic of the body to react to the use of substances included in this drug.

Any side effects, except for an overdose, are not a reason to stop the course of treatment, since these effects are not dangerous and they disappear without a trace as soon as the course of treatment is completed.

Who is the drug contraindicated for?

Klion D is contraindicated for women who have blood problems, as well as diseases such as epilepsy, stroke, liver disease, and is not recommended for use in girls under 12 years of age or if there is an allergy to any component of the drug.

The main thing to remember is that the use of any drugs can only be carried out as prescribed by a doctor and under his supervision.

Klion D is considered an antibacterial, antiprotozoal and antifungal medicine. This medicine is intended for topical use in gynecology.

Effect of the drug

Klion-D is a drug that is manufactured in the form of tablets, vaginal, suppositories or ointments. Most often, vaginal tablets are prescribed. The medication contains 100 mg of nitrate. This also includes additional substances, such as:

  • sodium lauryl sulfate (0.5 mg);
  • colloidal silicon dioxide (7 mg);
  • magnesium stearate (13 mg);
  • povidone (26 mg);
  • sodium bicarbonate (90 mg);
  • tartaric acid (100 mg);
  • sodium carboxymethyl starch (100 mg);
  • crospovidone (100 mg);
  • hypromellose (190 mg);
  • lactose monohydrate (473.5 mg).

One cardboard box contains 10 tablets.

As for the pharmacological action, this drug belongs to the combination of drugs. It has antibacterial, antifungal and antiprotozoal properties. This product is intended for intravaginal use.

As mentioned above, Klion tablets include metronidazole, which is aimed at the biochemical reduction of the 5-nitro group. Aerobic microorganisms can resist the action of this substance, and this also applies to facultative anaerobes. However, if the flora is mixed, then metronidazole together with antibiotics have a synergistic effect.

Miconazole has an antifungal effect, which is aimed at eliminating dermatophytes and yeast fungi. It is important to note that this substance is not capable of negatively affecting the normal composition of microflora or the pH level in the vagina.

Indications and contraindications

If we talk about indications, this medication is intended for the local treatment of vaginitis with mixed etiology, which can be caused by dimorphic fungi (for example, Candida spp.)

Like other medications, Klion has the following contraindications:

  • leukopenia (including in history);
  • organic lesions of the central nervous system;
  • liver failure;
  • bearing a fetus in the 1st trimester;
  • lactation period.

In addition, this product is not recommended for use by children under 12 years of age, as well as by people with hypersensitivity to the components included in this drug, or with hypersensitivity to other azoles.

Particular care should be taken when prescribing the drug to those people who suffer from diabetes mellitus and microcirculation disorders.

Dosage and overdose

The instructions for use state that the product treats intravaginally. At the same time, it can be not only pills or suppositories; There is also another form of the drug Klion: ointment, which also has a broad antimicrobial effect.

Most often, the tablet form is prescribed. In this case, the dosage should not exceed that prescribed by the doctor. Take the medicine before bedtime for 10 days.

If you do everything correctly, you will not need to think about the consequences that an overdose can lead to. If you also use Metronidazole in combination with Klion, some systemic effects may occur.

So, a person often experiences the following side effects, which indicate an overdose. This should include:

  • nausea;
  • pain in the abdominal area;
  • vomiting;
  • diarrhea;
  • unpleasant taste in the mouth;
  • ataxia, that is, movement disorder;
  • generalized itching;
  • paresthesia;
  • dizziness;
  • convulsions;
  • peripheral neuropathy;
  • leukopenia;
  • change in urine color.

Side effects that could be caused by Miconazole in case of overdose have not been identified.

If a person accidentally takes a large number of tablets orally, then it will be necessary to apply additional treatment, namely, rinse the stomach, administer activated charcoal, and perform hemodialysis. If any of the listed signs of overdose have been identified, then therapy should be carried out to eliminate the symptoms and aimed at supporting the body.

It should be noted that Miconazole has low systemic absorption, so metronidazole, which can be compatible with both antibiotics and sulfonamides, interacts with other medications.

It is important to know that this drug should not be consumed together with alcoholic beverages, as this can cause a reaction in the form of cramping pain in the abdomen, nausea, vomiting, skin flushing, and headache. In addition, the medicine under discussion cannot be taken together with Disulfiram, since this can cause an additive effect, that is, the person will have confused consciousness.


Klion can enhance the effect of drugs such as indirect anticoagulants, so the doctor must adjust the dose of the latter drug.

Moreover, metronidazole should not be combined with a non-depolarizing muscle relaxant. But cimetidine can inhibit the metabolism of the drug under discussion, which, in turn, leads to an increase in the concentration of the latter in the blood serum, and therefore increases the risk of side effects.

Pregnancy and menstruation

Klion-D during pregnancy should be used after the 12th week. Before this period, this drug should not be used, since the substances that make up it can be absorbed into the blood and penetrate to the fetus through the placenta. Therefore, starting from the 13th to 40th week, the product is allowed to be used, but if you have a choice, it is better to refuse it. For this reason, this drug should only be prescribed by a specialist who can weigh all the risks. But at the same time, there is no accurate information that would indicate that Klion-D can harm a child.

But what is strictly prohibited is the use of this drug while breastfeeding, since the components that the drug contains are absorbed into the blood, and then enter the breast milk and the child’s body.

Klion-D is also not recommended by doctors during menstruation. There are several reasons for this. Thus, the blood that is in the genital tract can reduce the effectiveness of the drug substances. In addition, during menstruation, the components of the pill will come out along with the blood, so the product simply will not work. Klion-D, which gets rid of pathogens, will not have any effect, and the treatment itself will not bring the expected result. For this reason, menstruation that begins during treatment leads to interruption of therapy. It must be continued after the end of menstruation.

Klion-D for thrush is prescribed by a doctor who takes into account all the patient’s characteristics. In addition, during treatment with a drug for thrush, it is recommended to carry out therapy with a sexual partner. This is carried out even if he does not have any symptoms. If you refuse treatment, there is a risk of relapse of the disease.

During this therapy, you must completely abstain from sexual contact. When a drug is prescribed for a long period, you need to monitor your blood and take regular tests. After the course of treatment is completed, it is important to see a doctor and follow the recommendations received.


During the treatment of a particular disease, a person is faced with a certain reaction of the body, which is easily confused with a side effect. Often, even after Klion D, many women suffer from discharge of an unusual nature, immediately falling into panic and trying to quickly find the cause.

Klion D is considered an effective and safe drug, which during therapy can cause unusual secretion. But you need to figure out exactly which leucorrhoea is associated with the drug, and which secretion may indicate other problems in the reproductive system.


What do you need to know?

Klion D 100 has proven itself well as a combined topical drug, which doctors prescribe for infectious diseases of the female genital organs. But each body reacts individually to the drug, so not all women experience discharge.

It is important to note that not all vaginal discharge can be associated specifically with the action of suppositories. Many factors play an important role here:

  • advanced disease,
  • nature of the pathology,
  • presence/absence of pregnancy,
  • patient's age,
  • presence/absence of allergic reactions,
  • the presence of other problems with the reproductive system.

Is the drug safe?

Let us immediately note that the product, due to its local effect, has minimal impact on the human body, while maintaining high efficiency. These vaginal tablets have several positive effects:

  • antibacterial,
  • antiprotozoal,
  • antifungal.

Metronidazole is responsible for the effect on protozoan microorganisms and bacteria, and miconazole has an antifungal effect. The first active substance blocks the proliferation of bacteria, thereby causing their death. And miconazole suppresses the synthesis of ergosterol, after which salts and water penetrate the fungal cells, disrupting metabolic processes there.

Both active substances affect only microorganisms and do not in any way affect the vaginal microflora and acidity level. Therefore, we can conclude that the drug does not provoke pathological secretion, and its appearance may be associated with the removal of epithelial cells, bacteria, single leukocytes, etc. from the vagina.

The nature of discharge after Klion D

Vaginal secretion after using Klion suppositories can vary in color, smell and consistency. In most cases, fairly liquid or semi-liquid leucorrhoea occurs, which can have a rather pungent odor. Sometimes white cheesy discharge appears, which could have bothered the woman before, but not in such quantities.

What worries women most is spotting, but it is not the drug itself that causes it, but a pronounced inflammatory process in the vagina. In this case, orange, brown and pink discharge may also appear. But if the patient is not pregnant, then there is no cause for concern, and treatment should be completed, provided there are no signs of intolerance to the drug or an adverse reaction of the body.

Duration of secretion

Specific vaginal discharge may begin immediately after the first procedure or after stopping treatment. In some situations, a woman notices unusual leucorrhoea even before therapy, which becomes the reason for visiting a doctor. Here, the amount of secretion at the time of treatment may increase, and this is considered normal.

It is worth noting that unusual discharge may continue to bother you for several weeks. But if this continues longer, then a visit to the gynecologist cannot be postponed.

It is possible that the case turned out to be too advanced and more serious medications are required, or the woman did not follow the doctor’s recommendations regarding the number of procedures.

Discharge during the treatment of Klion D candidiasis

Thrush, although considered a harmless disease, can cause serious harm to the vaginal microflora. Very often, infectious agents do not make themselves felt for a long time until an exacerbation occurs or the immune system weakens.

As a result, copious discharge occurs with a thick consistency, similar to cottage cheese or curdled milk.

In addition to fungi, the secretion may contain leukocytes and dead mucosal cells. After treatment, such discharge should go away or remain until the vaginal microflora is completely restored.

Also, often a woman, without realizing it, re-infects the vagina. That is why, during treatment with vaginal tablets, doctors recommend abstaining from sex, and also forcing your partner to also undergo treatment.

When treating colpitis with suppositories

If a woman is bothered by watery or foamy discharge with pus, then colpitis can be assumed. With this disease, vaginal secretions may become thicker over time due to severe desquamation of epithelial cells. There is also a very unpleasant odor, which can even be called fetid.

During treatment, the amount of secretion may increase, but by the end of the course it becomes less and less. In rare cases, this disease causes bleeding, the occurrence of which may occur just at the time of using vaginal tablets. But leucorrhoea with blood does not indicate the effect of the drug Klion, but a very severe form of colpitis, which will require more serious treatment.

Secretion during the treatment of vaginitis with suppositories

There are several types of vaginitis, each of which has its own characteristic features, also relating to vaginal secretion. She may be:

  • thick with a white-yellow tint, purulent;
  • frothy green or yellow;
  • abundant deep yellow;
  • in the form of loose white flakes;
  • transparent with a fishy smell.

In some cases, there is no discharge before treatment, especially in the chronic form of this disease. During treatment, vaginal secretion may increase, but should not continue after therapy for more than two weeks.

Could this be due to an overdose?

Discharge after Klion D cannot in any way be associated with a violation of the dose when used locally. But if the patient takes metronidazole orally along with vaginal tablets, the following may appear:

  • pain in the abdomen,
  • stomach upset,
  • itching and burning,
  • metallic taste,
  • headaches and dizziness,
  • darkening of urine.

Is it possible for pregnant women?

Note that Klion D is prescribed extremely rarely during pregnancy, and only in cases where the expected effect is higher than the possible risk. The instructions indicate that the use of these vaginal tablets is allowed in the second and third trimester.

Studies have not been conducted on women, but in animals it was metronidazole that had a toxic effect on the fetus. Although many doctors claim that the drug does not threaten the health of the unborn child. In any case, the product must be used very carefully under strict medical supervision.

After all, the discharge that appears after Klion D may not be associated with the use of the drug, but a woman may think differently. See our article about what may be the causes of discharge during pregnancy. In the second and third trimester, any bloody, pink (scarlet) or brown discharge requires diagnosis. They can occur as a result of inflammatory processes, a gynecological examination, after sexual intercourse, or be a signal of problems with the health of the woman and her fetus.

Klion D during menstruation

It is not recommended to use suppositories during menstruation, because the effectiveness of the active ingredients decreases greatly in such conditions. It can also affect the entire course of treatment, rendering it useless. And all this is due to the excretion of part of the vaginal tablet along with menstrual flow.

If the patient is about to have her period, it is better to postpone the course of treatment. But if menstruation began unexpectedly during therapy, then it is better to continue using Klion D, later warning your gynecologist about it. In addition, just before the onset of menstruation, a woman may notice secretion with blood, which will not be similar to the usual signal of the beginning of menstruation.

Klion D - analogues

If Klion D is not suitable or is ineffective, you can try other medications. There are synonymous drugs:

  • Neo-Penotran,
  • Neo-Penotran forte,
  • Metromicon-Neo.

These drugs have a different name, but have the same composition.

  • Vagiferon,
  • Clomegel,
  • Vagisept,
  • Ginalgin,
  • Gainomax.

A course of treatment with Klion D vaginal tablets can be carried out several times if the first course is ineffective. But if the treatment has to be repeated frequently, then it is necessary to conduct an analysis of the discharge, which will show the specific type of fungus, after which the doctor will be able to select the appropriate drug.

Women should remember that discharge cannot go away immediately in case of infectious diseases, because it takes time to restore the vaginal microflora. In addition, there may be other diseases of the reproductive system, which are the cause of certain discharges.

Klion D is a complex drug that is actively used in gynecology and obstetrics for the treatment of various diseases of the reproductive system. It contains components that provide rapid healing and restoration of damaged tissues and cells, relieve inflammation and suppress the growth of pathogenic microorganisms. However, when undergoing treatment therapy, many women note thatafter Klion dischargefrom the vagina begin to change their character - they become abundant and change their shade. Is this normal and is the appearance of discharge related to the use of the drug? Let's talk about this in more detail.

general information

Klion D 100 is a broad-spectrum drug that has the following properties:

  • antibacterial;
  • antiseptic;
  • antifungal;
  • anti-inflammatory;
  • regenerating;
  • antiprotozoal.

The drug is available in the form of tablets and suppositories for intravaginal use; they dissolve quickly and begin to exert their therapeutic effect almost instantly. Its high effectiveness is due to the presence of substances such as metronidazole and miconazole. Each of them has its own characteristics.

For example, metronidazole, even when used vaginally, is quickly absorbed into the systemic bloodstream and its high concentration is “retained” in it for 6-12 hours. Through the bloodstream, metronidazole penetrates into all structures of the female body - mammary glands, placenta, brain and spinal cord. However, it must be said that when using vaginal tablets, its effect on these structures is two times lower than when taking metronidazole orally.

Once this substance passes through the body, it enters the kidneys and most of it is excreted along with the urine, turning its color reddish or brown. The rest of metronidazole is excreted in the intestines along with feces. At the same time, it is metronidazole that suppresses the growth of protozoan microorganisms and bacteria.

Miconazole does not have the ability to be absorbed into the bloodstream, and therefore does not affect either the composition of the blood or the composition of urine. It acts directly on the vaginal mucosa, having a detrimental effect on fungal-like microorganisms (has an antifungal effect) for another 8-10 hours after administration.

Thanks to the properties of metronidazole and miconazole, Klion D suppositories have found their use in the treatment of pathogenic microorganisms such as:

  • Candida fungi;
  • trichomonas;
  • amoeba;
  • guardia;
  • Garderella;
  • bacteroides;
  • fusobacteria;
  • prevotella;
  • vilonella;
  • peptococci;
  • clostridia, etc.

Important! Considering such a broad effect of the drug and its high effectiveness against the above-described microorganisms, it is used mainly for the treatment of trichomoniasis, thrush, clostridiasis and other infectious and inflammatory diseases, the development of which was provoked against the background of the predominance of opportunistic or pathogenic microflora in the vagina.

Possible complications and consequences

As mentioned above, often when undergoing therapeutic therapy, women note thatdischarge after Klion D, which frighten them very much. In this case, most often patients complain of the presence of bloody, pink, white, yellow or green discharge from the genital tract.

But it should be said right away that this drug does not have any effect on hormonal levels and does not contribute to disruption of the vaginal microflora, and therefore its use simply cannot provoke the appearance of premature menstruation or the appearance of discharge associated with a violation of the acid-base balance in the vagina.

Since Klion D is used to treat infectious and inflammatory diseases, the appearance of vaginal discharge is quite natural, and many women detect it even before taking the drug.

Bloody discharge during the use of vaginal tablets is quite often associated with inflammation of the cervical canal, in which the walls of the vessels begin to lose their elasticity and become prone to damage. Moreover, the appearance of bloody discharge may be associated with the development of tumor diseases or hormonal disorders that a woman already has (they can occur both against the background of pathologies of the reproductive system and disturbances in the functioning of the endocrine system). Therefore, the occurrence of such discharge is not a reason to stop therapy, but a doctor’s consultation will still be required.

Pink discharge during the course of treatment is also not a reason to refuse further use of Klion D. Their appearance may also be associated with decreased vascular tone or erosive lesions of the cervix.

It is worth noting that pink and brown discharge often appears due to mechanical damage to the mucous membranes in the vagina due to improper administration of tablets. If there are no abdominal pains or other unpleasant symptoms, then there is also no cause for concern. It is necessary to study the instructions in more detail, paying special attention to the method of introducing the drug into the vagina.

White curd discharge

The appearance of abundant whitedischarge after Klion, similar in appearance to cottage cheese, exuding an unpleasant sour odor and provoking the appearance of itching and burning in the intimate area, indicates the development of candidiasis. In this case, you should also not stop using Klion D tablets, since they, on the contrary, will help suppress the growth of Candida fungi, which are the causative agent of this disease.

Important! If you have been diagnosed with thrush, you have been prescribed Klion D and after using it for a week your condition has not changed, you must definitely visit a doctor to change the drug!

Yellow discharge and leucorrhoea

Abundant yellow discharge and leucorrhoea while taking the drug are normal. Their appearance is caused by the removal of excess tablets from the vagina, which is why the mucous secretion turns yellowish or white.

Green discharge is always a sign of the development of infectious diseases in the organs of the reproductive system. They give off an unpleasant odor and are accompanied by itching and burning in the intimate area.

The appearance of these discharges while taking Klion D indicates the active removal of pathogenic microorganisms from the vagina. But if they continue for 7-10 days after starting to use the tablets, you should also visit a doctor.

What discharge is normal?

If the drug is used only as a prophylaxis and the woman does not have infectious and inflammatory diseases, then during the course of treatment she should not experience bloody, green or cheesy discharge. When using Klion, the appearance of mucous discharge from the vagina that does not have a specific odor and does not cause discomfort is considered normal.

The only thing a woman can notice at this time is an increase in the volume of secreted mucous secretion, which is caused by the activation of the glands located on the cervical canal as a result of the influence of the active components of the drug on them.

Important! If you experience black vaginal discharge while using Klion D, you should immediately go to the doctor! Their occurrence indicates the development of endometrial cancer of the uterus!

Overdose

When using vaginal tablets Klion D, an overdose is impossible. It can only occur if this drug is taken in combination with oral metronidazole tablets. And this condition manifests itself with symptoms such as:

  • nausea;
  • dizziness;
  • decreased appetite;
  • weakness;
  • brain fog;
  • headache;
  • metallic taste in the mouth;
  • convulsions;
  • stomach ache;
  • diarrhea.

If all these symptoms appear, you should stop taking the drug for a while and consult your doctor.

Features of application

To prevent the occurrence of side effects, including vaginal discharge, you must strictly follow the recommendations that are described in the instructions for the drug.

During the entire course of treatment, it is strictly forbidden to enter into intimacy with the opposite sex. In the event that complete refusal of intimacy is impossible, it is imperative to use contraception (condoms) during intercourse.

You cannot take tests for treponemes while taking Klion D, since due to the high concentration of the active substance metronidazole in the blood, the test may show false results, resulting in an incorrect diagnosis.

The drug reduces the level of leukocytes in the blood, and therefore, when taking it, you should periodically take a blood test. If leukopenia (low level of white blood cells in the blood) occurs, the use of tablets should be discontinued.

It should also be noted that even vaginal administration of Klion D can cause some disorders of the central nervous system. Therefore, during therapy, it is extremely undesirable to engage in activities that require increased concentration.

Under no circumstances should you combine the use of the drug with drinking alcoholic beverages, as this can lead to severe abdominal pain, nausea, skin flushing and other side effects.

When menstruation occurs, the course of treatment should be interrupted. This is due to the rapid removal of the drug from the vagina along with menstrual blood and a decrease in its effectiveness.

Is it possible to use during pregnancy?

During pregnancy, women are also often diagnosed with various infectious and inflammatory diseases that require urgent medical therapy, since if it is not carried out, it can negatively affect the health of the unborn child. And in this case, Klion D is also often used. However, there are some nuances here:

  • The drug may cause local side effects such as itching, burning and irritation, which may also result in an increase in the amount of vaginal secretion released.
  • When using Klion D, it is important to take into account the duration of pregnancy, since its active components have the ability to penetrate the placenta through the bloodstream and cause various defects in the fetus, and therefore at the time of the formation of internal organs and systems (this occurs throughout the first trimester), its use is contraindicated.

Important! If, while using Klion D, a pregnant woman begins to have brown or bloody discharge, you should definitely go to the doctor, as they may indicate spontaneous termination of pregnancy or the onset of premature birth!

Mode of application

The dosage and duration of use of Klion D 100 tablets are selected individually depending on the nature of the disease, its severity and the general condition of the woman. As a rule, the drug is used for 7-10 days. The tablets are administered once a day before bedtime. To make the process of inserting them easier and not lead to injury to the mucous membranes, the tablets should be lightly moistened with water before insertion.

It is necessary to understand that Klion D contains substances that are quickly absorbed into the blood and affect the entire body as a whole, despite intravaginal use. Therefore, in order to avoid negative consequences when undergoing therapy in the form of vaginal discharge, be sure to consult a doctor before the course of treatment.

Very often, the female body becomes vulnerable to pathological processes that are caused by pathogenic microflora. Vaginal fungi of the genus Candida can cause serious diseases, which are accompanied by pain and itching.

They create a risk of infecting a sexual partner, and at the time of birth they can infect a newborn. To eliminate these pathologies, medications are prescribed in the form of suppositories, which are used topically in gynecology and have the name Klion-D.

Compound

Klion-D vaginal tablets contain the following components in equal proportions:

  1. (an agent that suppresses bacterial microflora and has an antiprotozoal effect).
  2. Miconazole(antifungal agent)

Additional components included in this substance include:

  1. Silicon Acid.
  2. Magnesium sterate.
  3. Monohybrid lactose.
  4. Povidone.

These additional ingredients ensure good absorption and tolerability of this drug.

Pharmacological effects of Klion-D

Due to the fact that this drug optimally combines two potent dosage forms, the therapeutic effect in the treatment of fungal pathologies of various origins is achieved very quickly.

Dosage of Klion-D

  1. Klion-D vaginal suppositories usually need to be inserted once a day. They are best administered before going to bed.
  2. After their introduction, it is recommended to get out of bed as little as possible. This will ensure good absorption of the medicine.
  3. The duration of treatment is determined by the doctor, usually it does not exceed 10 days.
  4. It is best when Klion-D therapy is performed in combination, using tablet forms.

Mode of application

Before using Klion-D vaginal suppositories, you must perform the following procedure:

  1. A woman is recommended to do a good wash. In this case, it is necessary to use soft soapy substances that do not disrupt the normal acid-base balance. For this purpose, you can use soap that does not contain dyes, or soap for children.
  2. After this, the hands, especially the nail phalanges, must be treated with an alcohol-containing solution, using a cotton swab.
  3. Before inserting a vaginal suppository, you must take a lying position, moisten it in cool water, and with the pointed end, insert it as deep as possible into the vagina.

All these manipulations must be done quickly, since under the influence of the warmth of human hands, suppositories can lose their shape and consistency.

The use of Klion-D suppositories may be accompanied by an increase in vaginal discharge. This is not a dangerous sign, but the resulting stains on laundry can create problems during washing. To prevent this from happening, women are recommended to use sanitary pads throughout the course of treatment.

Indications for use

Gynecological infection is the main area of ​​application of Klion-D.

He is appointed:

  • When infected with Trichomonas.
  • In the case of candidal infections with a fungus of the genus candida.
  • Vaginitis of various etiologies.

Use of Klion-D suppositories during pregnancy

During the first trimester of pregnancy, the formation and formation of the internal organs of the future newborn occurs. Therefore, during this period, the use of candles should be avoided.

During subsequent pregnancy, the use of the drug is possible. But before this, the doctor carefully weighs all the pros and cons of this drug. Its appointment occurs in extreme cases, when a woman in labor really needs to eliminate the pathology that is caused by fungal microflora.

Also, Klion-D vaginal suppositories can be used before childbirth to cleanse the birth canal of pathological mycelium. This helps prevent infection of the newborn.

The ingredients of Klion-D suppositories pass into breast milk in small quantities, which makes it impossible to use this medicine. If an appointment nevertheless occurs, breastfeeding is temporarily stopped.

Using Klion-D for thrush

The course of treatment for this pathological disease should not exceed ten days. The recommended dose is a single use of vaginal suppositories before bedtime. Treatment is not carried out in the morning.

After 1 month, if necessary, the course of treatment can be repeated. If treatment is ineffective, a laboratory test must be performed.

Make a bacterial culture of vaginal contents and establish the tolerance of a drug that can resist bacterial microflora.

Use for trichomoniasis

The course of treatment, dosage, and method of application are exactly the same as for the treatment of thrush. It is also possible, if necessary, to extend the course after a month.

Use during menstruation

During the menstrual cycle, women experience bleeding from the vagina.

If you put a suppository with this drug at this time, it may partially dissolve in them, and as a result, it makes no sense to treat the disease, since its therapeutic effect is reduced, which leads to an incomplete cure from the pathological process of the disease.

Use of Klion-D for kidney and liver diseases

As noted earlier, Klion-D suppositories are not prescribed for severe liver damage (cirrhosis, hepatitis of various etiologies).

Renal failure, in the final stages, also precludes the use of this drug.

Contraindications

Klion-D candles have few restrictions on use. This is due to the fact that they are poorly absorbed into the blood, and their concentration in the body is insignificant.

But it should still not be taken in the following cases:

Side effects of Klion-D

Compared to other drugs of this pharmacological group, Klion-D suppositories are considered low-toxic and cause few side effects.

Sometimes the following symptoms may appear:

  • The appearance of local discomfort. The patient may experience redness, a feeling of the presence of a foreign body in the vaginal area, the genitals may be very itchy, burning, and swelling of the genitals.
  • Elevated.
  • Sometimes severe migraines occur.
  • From the digestive system There may be a taste disorder, dryness of the mucous membranes of the oral cavity, nausea, spasticity, increased gas formation, diarrhea.
  • On the skin Sometimes urticaria may occur, and in very severe cases, but extremely rarely, Quincke's edema may develop.
  • The blood formula and the color of urine may change.

Overdose

When using Klion-D suppositories, the appearance of overdose symptoms is reduced to almost zero.

But if the drug is taken for a very long time, and the patient has a history of allergic reactions, then the body may be poisoned by this medication.

Also, the clinical picture of overdose may appear if additional, oral use of metronidazole occurs in the treatment of pathological conditions.

Patients experience:

  • Nausea, which is accompanied by vomiting, and a metallic taste appears in the mouth.
  • There may be pain on palpation of the liver.
  • In rare cases, seizures and paresthesia may occur.
  • The most severe manifestation of an overdose is the appearance of Quincke's edema or anaphylactic shock.

At the first signs of an overdose, the patient must:

  1. Rinse the stomach using a sufficient amount of water, at least 2 liters.
  2. Cleanse the intestines. To do this you need to give an enema.
  3. Be sure to take enterosorbent, it can be Polysorb, Enterosgel, Sorbex, white activated carbon.
  4. It is advisable to put the patient to bed and, due to dehydration, give a warming drink.

If the symptoms of an overdose do not disappear, it is advisable to contact a medical facility.

Action with alcohol

This medicine cannot be combined with the use of alcohol.

Alcohol suppresses the effect and positive effect of Klion-D suppositories, and also, in tandem with this medicine, has a negative effect on the liver.

And very often it can cause increased side effects, ultimately serving as a reason to discontinue this medication.

Sometimes, under the influence of alcohol, a patient may experience a disulfiram-like reaction.

It is accompanied by the appearance of acute, paroxysmal pain in the lower abdomen, the occurrence of uncontrollable vomiting, the appearance of headaches, and sudden flushes of heat and blood to the face.

special instructions

To prevent unwanted side effects, you must follow certain rules when using this drug:

  • If there are clear contraindications, then the use of suppositories is excluded.
  • Concomitant use with alcoholic beverages is not allowed.
  • When breastfeeding, young mothers are advised to take a break if this drug is prescribed.
  • Combining this medicine with antibacterial therapy requires special care to avoid unwanted side effects.
  • If anticoagulant therapy occurs simultaneously, treatment should be carried out under the supervision of a doctor. This will avoid sudden bleeding.
  • Be careful when driving vehicles. Since this drug can influence a person’s reaction and behavior in emergency situations.

A good, correct effect from the use of Klion-D suppositories can only be achieved if all the rules and regulations for their use are followed.

Therefore it is necessary:

  1. If treatment is prescribed, the instructions provide for therapy of the sexual partner. Otherwise, re-infection may occur.
  2. During treatment, if work is associated with complex automatic processes, it is better to abstain from it; you must take sick leave for the entire period of treatment.
  3. Having sex during therapy is unacceptable.
  4. It is imperative to monitor, with the help of laboratory tests, the clinical state of the blood (monitor the number of leukocytes and the state of the leukocyte formula).

Interaction

Klion-D suppositories are often used in combination with other medications:

Analogues

There are a very large number of substitutes for the drug Kliona-D.

They can be conditionally divided according to their chemical composition. That is, have an identical chemical composition, or be based on an ingredient that, in the instructions for use, will be similar in action to candles with Klion-D.

Let's consider several analogues:

  1. Metromicon Neo. Its composition almost completely corresponds to the components of Klion D. It has a wider spectrum of action, as a result of which it can replace the drug Klion D in the treatment of amebiasis and giardiasis, pathological processes that are caused by anaerobic infection.
  2. Vagiferon. This drug has indications similar to Klion-D, but unlike it, it is active against mixed infections, herpes simplex virus, mycoplasma. Contraindications mainly apply to pregnant women and girls under 18 years of age.
  3. Metrovagin. A medication based on metronidazole, with a pronounced antibacterial and antimicrobial effect. The main condition for achieving the full therapeutic effect is use by both sexual partners and complete abstinence from sexual intimacy for the entire period of treatment. The medicine is available only in the form of ointment, helium or vaginal suppositories. Its big disadvantage is its many contraindications.
  4. Vagisept. A good analogue, with a good chemical composition (Fluconazole, Metronidazole).
  5. Genisol. A medicine containing miconazole nitrate (100 mg). Effective against gram-positive microorganisms and fungal infections. Not used in the second and third trimester of pregnancy. Renal failure is a reason to discontinue the drug.
  6. McMiror. It is a good remedy for the treatment of pathologies caused by vaginal trichomonas or candida fungus. Its use is limited only to cases of hypersensitivity. This is the main criterion when the drug is contraindicated. In some cases, instead of suppositories, you can use vaginal cream, which is sold along with a convenient applicator.

McMiror

Metromicon

Metrovagin

Vagiferon

Vagisept

In any case, you should adhere to the prescription made by the doctor. But sometimes, due to financial problems, it is impossible to buy medicine in this price category. In this case, you can use cheaper substitutes.

These include:

  • Difluzol (price does not exceed 70 rub. ).
  • Ithrakon ( 100 rub.).
  • Econazole ( up to 90 rub.).
  • Polygynax ( 90 rub. ).
  • Pimafucin ( up to 150 rub.).
  • Santequin ( no more than 130 rub. ).

Ithrakon

Pimafucin

Polygynax

Santequin

Difluzol

Price

In the pharmacy chain, this medicine has a price that fluctuates from 270 to 500 rubles for 10 pieces. Candles are produced in cardboard packaging. They are accompanied by an annotation on the use of this medicine.

Substitutes can be purchased at the following prices:

  1. Neo-Penotran 14 candles can be purchased for 930 rub.
  2. Metrovagin a package of ten suppositories will cost from 420 to 500 rubles.
  3. Metromicon-Neo. The cardboard packaging contains 2 blisters of 7 pieces. The price of this dosage form does not exceed 450 rubles.

The price in a pharmacy is higher than in an online store.

But this does not mean that when purchasing a medical drug outside a pharmacy network, you will be provided with insurance that will allow you to avoid purchasing a counterfeit.

Every girl who has reached puberty knows that about once a month there comes a period when you just want to climb the wall, because you cannot understand your body. First of all, you must understand that everything that happens to you is absolutely normal. Your mood changes in a second, you want to eat, you feel nauseous, your legs and back hurt, and at the same time someone may not be able to sit still. And all this happens because our body and organism become many times more sensitive.

What are Klion D candles?

Klion D suppositories are a local drug. With its help, women are treated for genital infections, in particular trichomoniasis and candidiasis. This drug is available in the form of vaginal tablets that must be inserted into the vagina. Fights microorganisms that cause disease. Antibacterial and antifungal candles. This medicine is produced by the world famous Hungarian pharmaceutical company GEDEON RICHTER. In pharmacies, Klion D suppositories are sold in packages containing 10 oval, white tablets with a pointed end, on one side of which there is an engraving “100”.

This drug contains a substance called metronidazole. It is very quickly absorbed into the blood, penetrates into breast milk, and through the placenta reaches the fetus in pregnant women; it also penetrates the spinal cord and brain. About 60 to 80% of the substance is eliminated from the body by the kidneys during urination, and the urine may be reddish or brown in color. The remaining 20 to 40% are excreted from the body in feces through the intestines. Another substance in the drug that also has an active effect on the body is miconazole, but it is almost not absorbed into the blood and remains in the body for a long time.

How does Klion D work?

When its substances enter the body, they have a suppressive effect on the synthesis of microbial DNA, for this reason, reproduction for microorganisms becomes impossible; microorganisms that have already managed to reproduce die due to the fact that under the influence of the substances, fungal cells become permeable to water and salts that enter the cell upset its balance.

The big advantage of this drug is that the substances contained in this drug act selectively, they destroy only pathogenic microorganisms, while beneficial bacteria remain unharmed, the composition of the microflora and acidity of the vagina does not change.

Pathogenic microorganisms that die under the influence of this medicine:

  1. Candida fungi;
  2. Trichomonas vaginalis;
  3. Vaginal amoeba;
  4. Gardnerella;
  5. Guardia;
  6. Bacteroides;
  7. Fusobacteria;
  8. Vilonella;
  9. Prevotella;
  10. Clostridia;
  11. Eubacteria;
  12. Peptococci;
  13. Peptostreptococci.

How to use the drug?

Klion D suppositories must be inserted deep into the vagina; this is done using a finger. Before starting the procedure, you must thoroughly wash your hands and also wash your external genitalia using warm water and soap. Just before insertion into the vagina, the tablet must be wetted, the water must be clean and warm. It is necessary to administer 1 tablet per day, it is better to do this in the evening, just before bedtime. The course of treatment is 10 days. To increase the effectiveness of treatment, it is better to accompany local therapy with these vaginal tablets by taking one tablet orally in the morning and evening Klion or Metronidazole, also for 10 days. It is recommended to take the tablets orally during or after meals; under no circumstances should you chew the tablets; you must swallow them whole.

If a course of treatment of 10 days does not produce results, it is necessary to extend it for another 10 days. Treatment is necessary not only for the woman herself, but also for her sexual partner. He also needs to take metronidazole tablets by mouth. If there is a need for several courses of treatment in a row, then you can repeat it as many times as necessary. But still, if it happens that Klion D suppositories did not help after two courses of treatment, then you need to consult a doctor to do research on the sensitivity of the fungus that caused the disease to the drug. Perhaps in this case the disease needs to be treated with another drug.

Klion D during pregnancy

For up to twelve weeks, the use of Klion D suppositories is contraindicated, since metronidazole, which is included in its composition, is absorbed into the blood and penetrates through the placenta to the fetus. You can use the drug from the thirteenth to the fortieth week of pregnancy, but if possible, it is better to avoid it. It should be used only after all possible risks and all intended therapeutic effects have been weighed. Although there is no exact information about whether the drug is harmful to the unborn child. The experiments were carried out only on mice; experiments have not been carried out on pregnant women and are unlikely to ever be carried out. As a result of the experiments, it was revealed that if pregnant rats and mice were administered the drug and the dosage was appropriate to their bodies, then no negative effect on the fetus was detected, but when mice and rats were administered a dose of the drug such as that received by humans, it was found that the drug has a toxic effect on the fetus.

Klion D during breastfeeding?

Doctors unanimously say that under no circumstances should you combine breastfeeding with the use of this medication. Why? Yes, for the reason that the substances that Klion D vaginal suppositories contain penetrate into the blood, and from the blood into breast milk, and with milk these substances enter the child’s body. This leads to the conclusion that the drug should not be taken simultaneously with breastfeeding. If the use of tablets during this period cannot be avoided, then it is better to stop breastfeeding the baby while the mother is undergoing treatment. After the course of treatment has been completed, two days after using the last vaginal tablet, you can resume breastfeeding.

Klion D during menstruation

Doctors do not recommend using this method of therapy during menstruation, since, firstly, blood in the genital tract and organs greatly reduces the effectiveness of the active ingredients of this vaginal drug. Secondly, during menstruation, particles of the dissolved tablet also come out of the vagina with menstrual blood. It turns out that the required amount of active substances, which are aimed at destroying pathogens, decreases and becomes insufficient to fight the disease, therefore, treatment becomes ineffective. Therefore, if a woman has her period, then she should not start using the pills; it is better to wait until her period ends and continue the course of treatment after the end of menstrual bleeding. If during the course of treatment your periods unexpectedly begin, you can either refuse treatment and continue it later, or continue to use vaginal tablets, but you should remember that the treatment will not be effective enough.

Regimen during the course of treatment

It is necessary to observe a regime of refusal of any sexual contacts with any partners during the entire course of treatment. If it is impossible to completely refuse sexual relations due to taking Klion D, then it is necessary to use a condom during sex.

When using this drug, it is strictly not recommended to test for treponemes, since the substances contained in this medicine will cause incorrect test readings.

While using this drug, a decrease in the number of leukocytes in the blood may occur; for this reason, while using these vaginal tablets, it is necessary to periodically take blood tests.

Combination of Klion D with other medications

The use of Klion D can be combined in parallel with antibiotics and sulfa drugs, regardless of the method of taking them - injections or tablets.

You should not drink alcoholic beverages during the course of treatment, as alcohol affects consciousness, the liver, muscles and coordination of movements, so alcohol can cause side effects - nausea, vomiting, dizziness, redness of the skin.

Side effects

Attention disturbances may occur as the drug affects the nervous system. While taking the drug, you should avoid any activities that require good reaction, concentration, and attentiveness, for example, you should not drive a car, or perform work on an assembly line, etc.

If only the vaginal version of the drug is used without concomitant drug therapy, then an overdose is impossible. If it is used in combination with tablets for oral administration, then in case of an overdose various side effects may occur: diarrhea, vomiting, nausea, abdominal pain, itching on the skin, a metallic taste in the mouth, coordination of movements (ataxia), dizziness, convulsions, red urine, crawling sensations on the skin.

If the symptoms of an overdose are obvious, then an urgent gastric lavage is necessary, then you should take activated charcoal, polyphepane, and in case of severe intoxication of the body you will even have to undergo a hemodialysis procedure. Next, you need to act according to the situation, that is, based on what side effects are observed, these effects should be treated specifically.

In addition, women using this drug may experience adverse reactions such as unusual discharge from the external genitalia, itching and burning of the genital mucosa, and a feeling of discomfort. The discharge is most often mucous, transparent or white, with a slight odor. Sometimes the discharge is thick, with white flakes and an almost imperceptible odor. Some women may have orange, brownish or red discharge, which is caused by blood. Discharge mixed with blood is the result of the fact that the vessels located in the vaginal mucosa are injured, and they are injured due to inflammation. Even if such discharge occurs, there is no need to stop treatment, just as there is no need to visit a gynecologist. Discharge may continue for two weeks after use of the drug is stopped. Discharge, such as sensations of itching, burning, pain inside the vagina, is a normal phenomenon, do not be afraid of them. These symptoms can occur at any time during the course of treatment, for some on the first day, for others only on the fifth day - this is an individual characteristic of the body to react to the use of substances included in this drug.

Any side effects, except for an overdose, are not a reason to stop the course of treatment, since these effects are not dangerous and they disappear without a trace as soon as the course of treatment is completed.

Who is the drug contraindicated for?

Klion D is contraindicated for women who have blood problems, as well as diseases such as epilepsy, stroke, liver disease, and is not recommended for use in girls under 12 years of age or if there is an allergy to any component of the drug.

The main thing to remember is that the use of any drugs can only be carried out as prescribed by a doctor and under his supervision.

When infectious diseases of the reproductive system are detected, the use of topical medications is often required. Klion D vaginal suppositories are easy to use and have a quick therapeutic effect: they destroy pathogenic microflora and relieve inflammation of the mucous membrane.

General information

Klion D - vaginal suppositories with a wide spectrum of pharmacological action. They are intended for the treatment of several bacterial, protozoal and fungal pathologies, as well as various multiple mixed infections. The drug has a pronounced therapeutic effect in certain types of STDs complicated by local immunity disorders or Candida fungi. In such cases, there is no need to use additional suppositories for thrush; Klion D works in several directions at once.

Suppositories can only be used as prescribed by a gynecologist after laboratory tests and confirmation of the diagnosis. The drug acts systemically on the body, its substances are absorbed into the general bloodstream.

Release form and dosage composition

Klion D is available in the form of intravaginal suppositories. The composition of the medicinal product includes:

  • 0.1 g of metronidazole - an antibacterial and antiprotozoal substance;
  • 0.1 g of miconazole - destroys pathogenic fungi and some pathogenic bacteria.

The basis of vaginal suppositories is vitepsol, an auxiliary fatty component that melts at body temperature.

The choice of release form depends on the intensity of the disease and the severity of accompanying symptoms.

Indications for use

Upon contact with the vaginal mucosa, the drug softens, releasing the active ingredients. Having been distributed over the surface, the medicine begins to work immediately, destroying fungi, protozoa and bacterial pathogens, including: Candida, Trichomonas vaginalis, gardnerella, anaerobic and some gram-positive bacteria.

The effectiveness of the drug is used in the treatment of the following diseases:

  • candidiasis;
  • trichomonas colpitis;
  • bacterial vaginosis;
  • mixed infectious vulvovaginitis;
  • sanitization of the vagina before and after completion of medical procedures;
  • complex therapy of cervical dysplasia.

Klion D vaginal tablets are used as a means of prevention, to eliminate residual inflammatory effects, and to treat gardnerellosis.

Use during pregnancy and lactation

Klion D suppositories are prohibited for use during pregnancy. One of the active ingredients of the drug, metronidazole, is a toxic compound. It penetrates into the blood and other biological environments, producing a teratogenic effect. It is especially dangerous to use this medicine in the first trimester, when the neural tube is forming and the internal organs of the fetus are being formed. The consequence can be serious neurological disorders in the born child. If the onset of conception was detected after the appointment of Klion D, the course is immediately interrupted.

Read also How to use tempalgin during menstruation

During pregnancy in the second and third trimester, the gynecologist can give permission to use Klion D in exceptional situations when the mother’s health is in serious danger.

During breastfeeding, the use of the drug is also contraindicated, since metronidazole easily passes into milk and can cause poisoning in the child.

Can it be used during menstruation?

During menstruation, the use of any topical medications is considered undesirable. A large amount of mucus, blood and endometrium leaving the uterine cavity makes inserting the pill into the vagina useless. The drug will slip out immediately, without having time to dissolve, or will flow out along with the secretions. It is also risky to take Klion D during menstruation because of possible irritation of the mucous membranes, which become much more sensitive during this period. It is recommended to interrupt local therapy during regulation and pre-calculate the course to avoid coincidences. Until the end of menstruation, it is recommended to use oral medications.

In cases of acute disease, the doctor may recommend using Klion D suppositories during scanty periods to avoid a subsequent surge in inflammation. This issue is resolved individually at the next consultation.

Klion D is unable to cause a delay in menstruation. If this happens, the cause may be an infectious disease against which the suppositories were used. It is possible to interrupt the course of treatment in the event of an unexpected failure without permission only if you suspect pregnancy.

Directions for use and doses

Klion D suppositories should be placed deep into the vagina. For ease of use of this drug, finger guards are included in the package. It is better to put suppositories at night. The horizontal position of the body will allow the medicine to remain inside longer.

For one course you should use 7 suppositories, administering them daily. In case of complicated infection, treatment is extended to 14 days.

Any methods of use other than intravaginal are prohibited. Suppositories should not be swallowed or placed into the anus.

Side effect

A few hours after the introduction of suppositories, white oily discharge from the vagina is possible. These are the remains of the base of the drug. To avoid staining your underwear, it is recommended to wear sanitary pads. You should not douche during the course.

The drug is well tolerated by most patients, but individual reactions of the body are likely.

Possible side effects of Klion D:

  • slight burning and itching of the mucous membranes;
  • redness, swelling;
  • skin rash;
  • dizziness;
  • bitterness in the mouth.