How much to give Motilium to a 5 year old child. Motilium for children, instructions for use will help you understand the purpose

The drug Motilium contains the active ingredient domperidone, which is a drug from the group of dopamine antagonists. Domperidone is a drug that speeds up the movement of food through the stomach and intestines. It is used to treat or prevent acid reflux (from heartburn), to relieve nausea and vomiting, to relieve the feeling of fullness after eating, and to reduce appetite.

The release form of the product is tablets, suspension (for newborns and small children) or lingual tablets.

How does domperidone work?

Domperidone blocks dopamine receptors in the upper digestive tract. This causes contraction of the muscles at the entrance to the stomach and relaxation of the muscles at the exit from it, and also enhances the peristalsis of the stomach itself. Therefore, the use of Motilium for diarrhea is inappropriate. These actions speed up the passage of food through the stomach into the intestines, which helps prevent vomiting and reduce nausea, bloating and fullness. Domperidone also prevents the backflow of food from the stomach into the esophagus.

Motilium also blocks dopamine receptors in the area of ​​the brain that are activated by nerve signals from the stomach. Once activated, it sends signals to the vomiting center. Blocking dopamine receptors prevents nausea and vomiting.

What does Motilium help with?

This drug has the following indications for use:

  • Stopping nausea and vomiting in adults and children.
  • Relief of abdominal discomfort and bloating, feelings of fullness, acid reflux and belching.

How to take the drug?

Dosage in adult patients:

  • To relieve nausea and vomiting, patients over 16 years of age may take 1 tablet 3 times daily for 2 days.
  • The tablet should be swallowed and washed down with enough water. Motilium should be taken before meals, since it takes longer for the drug to take effect when swallowed after a meal.
  • You cannot take more than 3 tablets per day.
  • You should not use Motilium for more than 2 days. If nausea and vomiting last longer, you should consult a doctor.


Directions for use in children:

  • Domperidone syrup should only be given to a child as prescribed by a doctor.
  • You need to take the drug strictly at the same time.
  • For heartburn, Motilium should be taken 30 minutes before meals.
  • Carefully measure the amount of syrup using a special syringe or measuring spoon.

Side effects

Frequent (develop in 1–10% of patients):

  • Dry mouth.

Uncommon (occurs in 0.1–1% of patients):

  • Diarrhea.
  • Decreased sexual desire.
  • Anxiety.
  • Insomnia.
  • Headache.
  • Rash or itching.
  • Weakness.
  • Pain or tenderness of the mammary glands.
  • Increased breast milk production.

Frequency unknown:

  • Hives.
  • Swelling of the face, tongue and throat (Quincke's edema).
  • Excitation.
  • Nervousness.
  • Cramps.
  • Uncontrolled movements of the arms, legs, face, neck, or tongue.
  • Increased prolactin levels, which can lead to breast enlargement in men (gynecomastia) or cessation of menstruation in women.
  • Difficulty urinating.
  • Abnormal heart rhythm.
  • Arrhythmia.
  • Liver dysfunction.

When should you not take Motilium?

Like any medicine, domperidone has its contraindications:

  • Allergy or intolerance to any of the components of the drug.
  • Pituitary tumor (prolactinoma).
  • Intestinal obstruction or perforation.
  • Black stools or blood in the stool may be a sign of gastrointestinal bleeding.
  • Liver or kidney disease.
  • Heart problems that show up on an ECG as a long QT interval.
  • Heart failure.
  • Low or high levels of potassium in the blood, low magnesium.
  • Taking certain drugs that prolong the QT interval.

Domperidone should be taken with caution in people over 60 years of age.
Motilium should be taken at the lowest possible dose.

Can Motilium be used by pregnant women and breastfeeding mothers?

There is currently no data on the safety of taking domperidone during pregnancy. Therefore, it should only be taken as prescribed by a doctor and in cases where the benefits outweigh the possible risks to the development of the fetus. You cannot use Motilium on your own for nausea in early pregnancy.

Domperidone passes into breast milk in small amounts that are most likely harmless to the baby. However, the instructions for use of the drug do not recommend its use in women who are breastfeeding unless the potential benefit to the mother outweighs any risk to the baby. If taking Motilium is necessary, it is better for the mother to stop breastfeeding for this time.

Motilium or Motilak - which is better?

Domperidone is found in many drugs, such as Motilium, Motinorm, Motilak and others. Having carefully studied the descriptions of these drugs, it is not difficult to understand what the difference between them is. Motilium is the original (branded) drug, and Motilak is its generic. Patients and doctors have broken many lines in disputes about which product is better - branded or generic? The original drug is believed to be more effective in most cases, but it almost always costs more than the generic drug. In addition, Motilak is available only in the form of lozenges, which means it is not suitable for small children.

Uncontrolled drug use is one of the huge problems of modern society. In conditions where every patient is his own doctor, when medications can be freely purchased at a pharmacy, the development of serious complications from taking medications has long been no surprise to workers in medical institutions.

One such drug that most people consider “harmless” is Motilium. In fact, this drug has quite dangerous side effects that can be life-threatening for the patient.

Motilium– an antiemetic that can improve the motility of the digestive tract. The drug owes its properties to its active substance - domperidone. The action of Motilium stops vomiting, stimulates the gastrointestinal tract, accelerating the excretion of liquid, semi-liquid or solid fractions (if they stagnate).

Indications for use of Motilium for children, as a rule, are caused by certain conditions accompanied by:

  • vomiting, nausea (cyclic vomiting, gastrointestinal reflux);
  • heartburn, belching (including regurgitation of newborns);
  • bloating due to excessive gas formation;
  • heaviness in the stomach.

That is why in the treatment of dyspepsia in pediatrics it is prescribed to take it. After all, in case of poisoning and similar conditions, the drug accelerates recovery, quickly and reliably restoring disrupted processes.

Motilium helps to fix the lower esophageal sphincter without changing gastric secretion. Relief comes in two days from the start of treatment.

Directions for use and dosage

The drug dosage regimen is covered in sufficient detail in the instructions for using Motilium. According to her, tablets are given to children only when their weight has already reached 35kg. Mainly in pediatric practice for the treatment of dyspeptic disorders use only suspension.

It is allowed to be given children from birth, however, to use the drug in children under one year of age, it is necessary supervision of the attending physician, since there is a risk of neurological disorders.

Naturally, the dosage of Motilium should be prescribed by a doctor, who will assess the child’s condition and his weight. Usually, for 10 kg of weight it is prescribed to take 2.5 mg of suspension three times a day.

When the need arises (in the acute stage), you can accept fourth time the same dose at night. In general, acute conditions (for example, vomiting) require the administration of 5 ml of suspension per 10 kg of weight up to 4 times a day. The maximum daily dose can be 80 mg of the drug.

Motilium should be taken a quarter of an hour before meals due to its rapid absorption. It is worth noting that it does not combine well with other means. Therefore, you should tell your doctor about taking any medications.

Required information

However, there are also Motilium contraindications, among them:

  • individual intolerance to domperidone;
  • sensitivity to lactose;
  • changes in glucose synthesis and absorption;
  • obstruction of the digestive tract;
  • stomach bleeding, etc.

Motilium is prescribed with caution to children, suffering from kidney and liver diseases.

Sometimes there are side effects of Motilium, which can develop into intestinal problems, spasms, allergies, and neurological disorders.

At compliance with the rules for taking the drug, no overdose was observed, however, it is still worth knowing its signs. If you notice drowsiness, lethargy or disorientation in your baby after taking Motilium, immediately stop the drug and give your child a sorbent (activated carbon). Be sure to report the incident to your doctor.

Price in Online Pharmacies

Motilium is an effective drug that helps with various gastrointestinal diseases by stimulating intestinal motility.

This drug has a pronounced antiemetic and antispasmodic effect. This makes it possible to reduce pain in the abdominal area. You can learn more about the positive and negative impacts from our material.

What does Motilium help with and what is its composition and active ingredient?

Motilium, where the main active ingredient is domperion, is used as an antiemetic drug and a stimulator of the functionality of housing and communal services. Features of this medicine is as follows - it has reduced bioavailability. Motilium increases gastric peristalsis, cleanses it of food debris, and has a positive effect on the performance of the sphinx of the esophagus.

As a rule, this medicine is often taken by those patients who complain of gastrointestinal upset. In addition, the components that make up Motilium increase the concentration of prolactin, which is in the blood.

The drug itself consists of:

  • Domperidone
  • Gelatin
  • Pulp
  • Aspartame
  • Sodium hydroxide
  • Sorbitol

In addition, the product also contains mint flavoring, which is needed to improve the taste of the product.

If we talk about the pharmacological qualities of the drug, then it is worth highlighting the most pronounced ones:

  • Thanks to the drug, the performance of peristaltic readings of the duodenum (duodenum) and stomach is accelerated
  • The medicine removes food from the stomach and duodenum faster. Food after the medicine does not linger long in the stomach, plus it does not irritate the stomach walls
  • The removal of food from the stomach is accelerated. As a result, it is excreted and digested faster, without rotting and fermentation.

Motilium: release form, indications for use, how long does it take to start working?

Today pharmacology offers this medicine in the following forms:

  • In the form of tablets, which are coated with a light coating
  • In the form of lozenges
  • As a suspension


Motilium is prescribed in the following cases:

  • During a dyspeptic phenomenon occurring in gastroesophageal reflux. As a result, gastric emptying slows down and esophagitis occurs.
  • For nausea and vomiting that occurs during Parkinson's disease.
  • For nausea and vomiting, which may be infectious, organic or functional.
  • For nausea and vomiting that appears after a violation of a particular diet, radiotherapy and treatment with other medications.
  • During cyclic vomiting, regurgitation syndrome and other changes associated with gastric motility.

As shown by reviews of people who have already taken this medicine, it begins to act differently. For some, the medicine helps on the first day of use, while others feel relief after a few days. It all depends on the disease itself and its intensity.

Motilium - at what age can it be given to children?

Motilium has a strong antiemetic effect. Often the drug is taken to normalize the functioning of the child’s digestive tract. Since you can buy several types of this medicine at the pharmacy, you can choose the best option for your own child.

So, for example, tablets of this drug are prescribed to those children who are already 5 years old and whose weight is more than 35 kg. Tablets that need to be dissolved are more suitable for adult patients, but in pediatrics, as a rule, a suspension is used for children under 5 years of age. And it’s not strange, since the baby will drink a syrup with great pleasure rather than a nasty pill.

Motilium - suspension, syrup, lozenges: abstract, instructions for use and dosage for newborns, infants and children over one year old with nausea, vomiting, diarrhea, regurgitation

If you follow the instructions correctly, the duration and dosage of the course of treatment for your baby will depend on several factors:

  • Depending on the form in which the drug is released
  • From the child's age
  • For a problem that parents want to solve by giving their baby Motilium

Each individual case has its own peculiarities of using the medicine. They must be taken into account in order to achieve the best efficiency.



Particular attention should be paid to the frequency of use and dosage of the medicine.

  • Suspension. The dosage of Motilium for an infant is calculated in the following ratio - for 10 kg of child weight you need to take 2.5 mg of suspension. The medicine can be given to children from the 1st month of life, 3 times a day.
  • Pills. The child is allowed to take 1 tablet before bedtime. For children over 12 years of age, during belching and heartburn, the dosage is as follows: 1 tablet 3 times a day. If there is no positive effect, doctors recommend increasing the dose, giving him 2 tablets at a time. During chronic nausea and vomiting, the dosage is as follows: children from 5 to 12 years old can take 1 tablet 4 times a day. The norm per day should be a maximum of 80 mg (8 tablets).

Motilium - suspension, syrup, lozenges: abstract, instructions for use and dosage for adults with nausea, vomiting, diarrhea

Pills:

  • Those tablets that need to be dissolved are taken throughout the day or before bed. The coated tablets are swallowed and cannot be bitten or chewed. They are washed down with plain water (1/2 tbsp).
  • The lozenge is placed on the tongue. You need to wait a little for the tablet to break up into small particles. The resulting particles are then swallowed. If necessary, they drink water. But if at this moment there is no water, then such a tablet is not washed down after disintegration.
  • The coated tablet is removed from the blister. However, there are no special precautions. But with those tablets that dissolve, you need to be extremely careful, since they are very fragile.
  • To prevent such a tablet from breaking or crumbling, it is advisable to trim the packaging with scissors and remove the tablet from its cell.
  • For adults, in order to eliminate belching, heartburn and other similar problems, doctors advise taking 2 capsules, 3 times. During nausea and vomiting, the dosage is as follows: 2 capsules, 4 times a day.

Suspension:

  • As a rule, doctors prescribe the suspension only to small children.
  • But adults can also take this medicine. The dosage in this case is as follows: 20 ml of motilium 4 times a day
  • The largest dose that is permissible for adults is 80 ml of the drug.

Motilium - suspension, syrup, lozenges: abstract, instructions for use and dosage during pregnancy and breastfeeding

During pregnancy, the drug is taken only when there is no risk of harm to the fetus itself. The dosage can only be prescribed by the attending physician of the pregnant woman. The drug is strictly prohibited during breastfeeding.

How to take Motilium for adults and children: before meals or after meals?

Motilium contains the active ingredient domperidone. It relieves the feeling of fullness in the stomach, as a result of which heartburn and belching disappear. Since all present symptoms decrease after eating, then it is advisable to drink the medicine before meals. If it comes to tablets, then this should be done in 15 minutes. before meals. During this time, the medicine will have time to have a positive effect.



The presence of food in the stomach reduces the absorption of the drug. As a result, the therapeutic effect is reduced. Therefore, drinking motilium after eating is simply irrational. The drug is ideally absorbed only on an empty stomach.

How to take Motilium for heartburn?

Almost all people are familiar with the burning sensation in the chest. Many people experience heartburn after eating certain foods. An unpleasant burning sensation is a process that occurs after the contents of the stomach are expelled into the esophagus. There can be many reasons for this condition:

  • Excess weight
  • Stressful regular conditions
  • Alcohol abuse
  • Disturbed diet and so on

It does not matter for what exact reason the heartburn occurred. Motilium will always come to the rescue. To get rid of the burning sensation forever, one medicine is not enough. It is also necessary to bring your own nutrition back to normal and forget about bad habits forever.

Motilium: duration of course, administration

  • Motilium is taken only before meals. The product is washed down with water (approximately 80 ml). The regimen for using the medicine is the same for everyone (except for small children): 1 tablet, 3 times.
  • The latter should be drunk in the evening before going to bed. The duration of the course of treatment is until the person’s condition normalizes.

Treatment with tablets:

Motilium in absorbable tablets is taken before meals, placing the product on the tongue. The recommended course duration is 1 week. You can take 3 tablets per day. The dosage is always the same, the time of administration is also:

  • 1st Prem – in the morning
  • 2nd reception - at lunch
  • 3rd dose – before bedtime


If the symptoms are severe, then it is recommended to increase the dosage. However, this should be done by visiting your doctor and consulting with him. You cannot increase the dose yourself, especially for children, as this can cause serious complications. The longest period of taking the medicine is 4 weeks. After this period has passed, Motilium should not be taken.

Motilium and alcohol: compatibility

The mechanism of action of Motilium is based on the following - the drug blocks dopamine receptors. Dopamine is a neurotransmitter through which nerve impulses are transmitted to nerve cells. As a result of this process, the stomach and the vomiting center, located in the medulla oblongata, cease to be connected. This is the reason why nausea and vomiting disappear.

At the same time, the tone and functionality of the smooth muscles that are located in the upper gastrointestinal tract increases. The tone of the lower sphincter in the esophagus also increases, which also stops vomiting.

IMPORTANT: Alcoholic drinks block the effects of dopamine components, and therefore the positive effects of motilium. Consequently, drinking alcohol will lead to the following - using motilium will simply be useless.

For example, during an overdose of alcohol, a normal person in good health, who practically does not drink, vomits - a protective function of the body that removes various poisons from the body. It is impossible to relieve such vomiting by drinking motilium.

Motilium or Espumisan, Domperidone, Motilak: what is the difference, which is better?

Medicines such as espumisan, domperidone and motilak are recommended for use during intestinal bloating, nausea, vomiting, hiccups of various origins, postoperative decrease in the tone of the walls of the stomach and intestines.

  • As for motilium, this medicine is complex. It promotes gastric emptying, has a positive effect on gastroesophageal reflux, eliminates esophagitis (a feeling of fullness in the epigastrium, a feeling of bloating and fullness of the stomach, pain in the upper abdomen).
  • It also easily copes with belching, flatulence, heartburn, plus it takes away the contents of the stomach.


Each drug, expensive or inexpensive, that was described above has its own contraindications. Therefore, each drug acts individually. And which of these medications is better can only be said by a person who has already used them.

How can you replace Motilium: analogues

The functionality of the gastrointestinal tract is the main basis of the human body. When any problems arise, it is very important that good health care is provided. When choosing medications for treatment, in order not to spend a lot of money, you should not buy those drugs that are cheap. Saving on your own health, as a rule, aggravates the disease.

But you shouldn’t chase very expensive products, as they are not always effective. It is important to correctly find a balance between price and quality of drugs. Motilium is considered the most effective medicine today. But it is possible to replace this medicine with another drug that is cheaper.

Ganaton:

  • The medicine helps during gastrointestinal diseases, relieves heaviness in the abdomen and bloating. It also eliminates nausea, vomiting, and awakens appetite.
  • The medicine should not be taken during pregnancy and lactation. It is also not recommended for use by children under 16 years of age and those with severe sensitivity.


Analogs of the drug for normalizing the gastrointestinal tract

Domperidone:

  • Helps with nausea, heartburn, bloating. Improves intestinal performance, normalizes the functionality of the gastrointestinal tract. It is also recommended to take this drug if your body has very high cholesterol levels and after surgery.
  • The medicine should not be taken if there is internal bleeding, during pregnancy or breastfeeding. You can also read about other contraindications in the detailed instructions.

Maalox:

  • An excellent drug that helps with many abnormalities associated with the gastrointestinal tract. It is considered one of the powerful remedies, but also has contraindications.
  • For example, it should not be used during renal failure, pregnancy, or Alzheimer's syndrome.

Motilium: contraindications, side effects

Tablets and suspensions can cause some side effects. There are also some contraindications. We will describe them in a little more detail.

Side effects:

  • Urinary system. Sometimes, after using this medicine, you may experience urinary retention and a feeling of heaviness in the lower abdomen.
  • Mental disorders. When taking motilium, nervousness rarely occurs and sleep disappears. Often such actions occur in children under 1 year of age.
  • Stress. Rarely, extrapyramidal symptoms develop after administration, as a result of which the secretion of certain hormones in the thyroid gland increases. This deviation appears in young children.
  • Immunity. Everything here is individual. Often the medicine is not capable of causing a negative effect on the immune system, but there have been cases when anaphylactic shock occurred.
  • Skin covering. Taking the medicine temporarily affects the condition of the epidermis. For example, swelling and urticaria occur.


Contraindications:

It is strictly forbidden to take the drug Motilium if there is bleeding in the gastrointestinal tract, during perforation or intolerance to certain components, in case of obstruction, if there is a danger of stimulating the motor work of the stomach. You are not yet allowed to take the medicine if you have prolactin, a secreting tumor of the pituitary gland. Doctors do not advise drinking during high sensitivity.

What is the shelf life of Motilium after opening?

The shelf life of tablets and suspensions differs significantly:

  • Tablets taken internally are stored for 3 years
  • Tablets that need to be dissolved are stored for 2 years

IMPORTANT: It is important to remember that if the drug has expired, it should not be taken. The drug is stored in a cool place. The maximum storage temperature should not exceed 25 °C.

Regurgitation often bothers newborns. Most often, they are caused by physiological characteristics and do not require special treatment. If regurgitation is persistent, profuse and negatively affects the baby’s weight gain, the pediatrician may prescribe a special diet that includes medications, one of which may be Motilium. In addition to newborns, Motilium can be prescribed by a doctor to children with nausea and vomiting.


Compound

The drug belongs to the pharmacological group of prokinetics - drugs that stimulate gastrointestinal motility. For children, Motilium is used in the form of a suspension. The active ingredient is domperidone in an amount of 5 mg per 5 ml of product. Excipients include: sweetener, thickeners, water and other components. Since the taste of the drug is sweet, Motilium suspension is often called syrup.

Indications for use

Before taking the drug in an infant, you must make sure that it is not vomiting caused by poisoning or infectious and inflammatory diseases of the digestive tract. Otherwise, there is a risk of harm rather than helping. Suppressing vomiting will lead to the accumulation of toxic products and microorganisms, which will worsen the child's condition.

Motilium can be used for poisoning in children accompanied by vomiting, only in combination with drugs that remove toxic products from the body. Most often, sorbents (Enterosgel) are used as such preparations. You must understand that the simultaneous use of Motilium and these drugs will reduce the effect of the first, so the difference in the time of administration should be at least 20 minutes.

Motilium enhances gastric motility, activates peristalsis of the esophagus and duodenum, and produces an antiemetic effect. Thanks to this, the retention time of food masses in the gastrointestinal tract is reduced. It is noted that in children, domperidone helps eliminate constipation, normalizing bowel movements.

Important! Taking Motilium should be agreed with your doctor.


What can Motilium help a child with:

  • regurgitation syndrome;
  • increased gas formation, feeling of bloating;
  • vomiting and nausea caused by indigestion;
  • nausea and vomiting of organic, infectious or functional origin;
  • motility disorders of the upper digestive tract.

Instructions for use of the suspension for children

A dosage pipette is included with the drug. Motilium is given to children 15-30 minutes before. before meals, as gastric juice reduces the absorption of domperidone. The drug can be taken before bedtime.

For dyspepsia (pain and discomfort in the epigastric region)

2.5 ml of suspension per every 10 kg of child’s body weight (250 mcg/kg of body weight) three times a day.

For nausea and vomiting

5 ml of suspension for every 10 kg of child’s body weight (500 mcg/kg of body weight) before meals or at night.

The maximum concentration of the drug in the body is achieved within 30-60 minutes after administration. The first results from the treatment of regurgitation will not be noticeable immediately, but after 2-3 days. The course of treatment with Motilium lasts on average 10-14 days.

Contraindications and possible side effects

  • bleeding in the stomach or intestines;
  • intestinal obstruction;
  • severe and moderate liver dysfunction;
  • prolactinoma;
  • hypersensitivity to the components included in the drug.

You should be careful when taking the drug if you have kidney problems. In such patients, the frequency of taking the drug should not be more than 1-2 times a day, and it is also possible to reduce its dosage.

In newborns and children during the first months of life, there is also an increased risk of neurological side effects due to the immaturity of metabolic processes and the blood-brain barrier. Strict adherence to the dosage prescribed by your doctor will help you avoid side effects.

Since Motilium belongs to the second generation prokinetics, it penetrates little through the blood-brain barrier and is less capable than the first generation prokinetics of causing adverse reactions in the form of drowsiness, weakness, fatigue, headaches, anxiety, tinnitus. Very rarely, rash and urticaria appear.

In case of overdose, drowsiness, disorientation, convulsions, and impaired consciousness are observed. No special treatment is required. It is recommended to perform gastric lavage and give activated charcoal. In the future, careful monitoring and rehabilitation therapy are necessary.


Analogues

Motilium has good reviews from mothers, but often the price stops them from buying the drug, forcing them to look for cheaper analogues. Finding an alternative to Motilium that is approved for use at home by children under one year of age is almost impossible. Recommended for use are drugs based on metoclopramide ( Cerucal), which are produced in the form of ampoules and are intended for use in a hospital setting. Unlike Motilium, they have more side effects, as they are able to penetrate the blood-brain barrier. Cheaper Motilak just like Motilium, it contains domperidone, but is sold only in tablets and is not allowed for children under 5 years of age.

Thank you

The site provides reference information for informational purposes only. Diagnosis and treatment of diseases must be carried out under the supervision of a specialist. All drugs have contraindications. Consultation with a specialist is required!

Motilium represents antiemetic, which also has the property of reducing the severity of dyspeptic symptoms (heartburn, flatulence, belching, nausea, vomiting, feeling of fullness and pain in the stomach after eating, etc.), caused by impaired evacuation of the food bolus from the stomach to the intestines. Therefore, Motilium is used to relieve vomiting, as well as relieve dyspeptic symptoms in reflux esophagitis, gastroesophageal reflux, GERD, esophagitis, gastric hypotension, as well as against the background of cytostatic therapy or radiotherapy of tumors.

Release forms, names and composition of Motilium

Currently, Motilium is available in the following three dosage forms:
1. Oral lozenges;
2. Film-coated tablets for oral administration;
3. Suspension for oral administration.

Coated and oral tablets are usually called simply “Motilium tablets” without specifying which type we are talking about. And the suspension is often called Motilium syrup in everyday speech. However, since Motilium does not exist in the form of a syrup, people use this term to designate the liquid form of the drug, without going into the subtleties of the differences between suspension, solution, syrup, emulsion, etc. In addition, the suspension is often called children's Motilium, since it is this dosage form that is used in pediatric practice.

All dosage forms of Motilium contain as active substance domperidone in the following different dosages:

  • Oral lozenges – 10 mg;
  • Coated tablets for oral administration – 10 mg;
  • Suspension – 1 mg per 1 ml.
Auxiliary components of all three dosage forms of Motilium are reflected in the table.
Lozenges Coated tablets Suspension
GelatinLactoseSodium saccharin
MannitolCorn starchSorbitol
AspartamePotato starchSodium hydroxide
Mint essencePolividonPolysorbate
Poloxamer 188Microcrystalline cellulose
Magnesium stearatePurified water
Hydrogenated vegetable oilSodium carboxymethylcellulose
Lauryl sulfateMethyl parahydroxybenzoate
HypromellosePropyl parahydroxybenzoate

Lozenges are round in shape and colored white or almost white. The coated tablets are round, white or cream-white in color and marked "Janssen" and "M/10" on their flat surfaces. If the coated tablet is broken, then at the break it will be uniformly white, without inclusions. Both types of tablets are available in packs of 10 or 30 pieces.

The suspension is a white, opaque liquid of uniform structure and jelly-like consistency. Available in 100 ml dark glass bottles.

What does Motilium help with (therapeutic effects)

Motilium has the following pharmacological effects:
  • Suppression of the activity of the vomiting center in the brain;
  • Increased intensity and duration of contractions of the stomach and duodenum;
  • Increased pressure in the esophagus;
  • Acceleration of evacuation of the food bolus from the stomach into the duodenum.
These pharmacological effects provide the therapeutic effect of Motilium, which consists of relieving the symptoms of indigestion (flatulence, belching, feeling of heaviness and pain in the stomach after eating, nausea, vomiting, heartburn, etc.) caused by stomach diseases in which the evacuation process is disrupted its contents (gastritis, peptic ulcer, reflux esophagitis, GERD, gastric hypotension), as a result of which food stagnates and does not pass into the duodenum in time.

Motilium improves the contractile activity of the stomach muscles, which leads to faster evacuation of the food bolus into the duodenum. And due to the fact that food does not stagnate and does not irritate the stomach, a person’s painful symptoms of dyspepsia (belching, heartburn, flatulence, etc.) go away. That is, Motilium helps get rid of the symptoms of stomach diseases in which food stagnates in it. And since these symptoms can also occur in a healthy person, for example, when overeating, eating fatty or unusual foods, or other violations of a normal balanced diet, Motilium will help in this case to get rid of the unpleasant sensations associated with a full stomach.

By increasing pressure in the esophagus, Motilium prevents gastroesophageal reflux, reducing heartburn and other symptoms (sour belching, etc.), as well as helping to cure GERD (gastroesophageal reflux disease). That is, Motilium helps relieve the symptoms of gastroesophageal reflux and GERD.

And thanks to the suppression of the activity of the vomiting center, Motilium is able to eliminate vomiting caused by an infectious disease, taking medications, various chronic pathologies of any organs and systems, as well as functional digestive disorders caused by the consumption of unknown or unusual food and other similar factors.

Motilium - indications for use

The suspension and both types of Motilium tablets are indicated for use in the following identical cases:
1. Relief of the following symptoms of gastric hypotension, gastritis, GERD, reflux esophagitis, gastroesophageal reflux, resulting from food retention in the stomach and its slow evacuation into the intestine:
  • Feeling of heaviness, pressure, or fullness in the stomach after eating;
  • Pain in the stomach after eating;
  • Bloating;
  • Belching, including sour contents;
  • Vomit;
  • Heartburn;
  • Regurgitation (reflux of a fairly large amount of stomach contents into the oral cavity).
2. Nausea or vomiting caused by infectious diseases, pathologies of any internal organs, or functional disorders (for example, errors in diet, motion sickness, eating too much food at once, etc.).
3. Nausea and vomiting caused by taking medications, as well as radiotherapy and chemotherapy for tumors.


4. Nausea and vomiting caused by taking Levodopa, Bromocriptine or other dopamine agonist drugs for parkinsonism.
5. Relief of nausea and gag reflex during medical procedures, for example, insertion of a gastric tube, production of endoscopy, etc.
6. Regurgitation syndrome in children.
7. Cyclic vomiting in children.
8. Gastroesophageal reflux in children.
9. Gastric motility disorders in children.

Instructions for use

Let's look at the rules for using both types of Motilium tablets in one section, since they differ slightly. We will consider the rules for using Motilium suspension in a separate section.

Motilium tablets - instructions for use

Absorbable, film-coated tablets should be taken 15 to 30 minutes before meals. Also, if necessary, Motilium can be taken before bed.

The coated tablet is simply swallowed, without biting or chewing, with half a glass of water. A lozenge is placed on the tongue and waited a few seconds until it disintegrates into small particles. After this, the resulting particles are swallowed and, if necessary, washed down with several sips of water. However, if for some reason there is no water, then the dissolving tablets do not need to be taken after they have disintegrated into small particles on the tongue and have been swallowed.

Coated tablets can be removed from the blister without taking any special precautions. And you need to be careful with dissolving tablets, as they are quite fragile. To avoid breaking and scattering of tablets, it is recommended not to squeeze them out of the blister through the foil, but to carefully trim the edge of the cell with scissors. You can also carefully remove the foil from one cell and remove the tablet from it.

To relieve symptoms of dyspepsia (belching, heartburn, flatulence, feeling of fullness in the stomach, etc.) in chronic diseases of the stomach and esophagus, adults and children over 5 years old should take 1 tablet 3 times a day before meals, and, if necessary, before sleep. If there is no effect, children over 12 years of age and adults can double the dosage, that is, take 2 tablets 3 times a day before meals.

For nausea and vomiting, to relieve them, children over 12 years of age and adults should take 2 tablets 3-4 times a day before meals and before bed. And for relief of nausea and vomiting, children aged 5–12 years should be given 1 tablet 3–4 times a day before meals and before bed.

For children 5–12 years old, the maximum permissible daily dosage of Motilium is 2.4 mg (1/4 tablet) per 1 kg of body weight, but not more than 80 mg (8 tablets). For adults and adolescents over 12 years of age, the maximum permissible daily dosage of Motilium is 80 mg.

For children under 5 years of age, the drug is given in the form of a suspension and the dosage is calculated individually according to body weight, based on the ratio of 2.5 ml per 10 kg of weight. Motilium tablets are not used in children under 5 years of age and weighing less than 35 kg.

Motilium suspension (Motilium for children) – instructions for use

The suspension is intended for use in children under 5 years of age and weighing less than 35 kg. In children of the first year of life, the drug should be used only as prescribed by a doctor and under constant supervision.

The suspension, just like the tablets, should be given to the child 15 to 30 minutes before meals and, if necessary, before bedtime. The amount of the drug, measured with a special syringe, must be poured into a spoon or into a small container (glass, glass, etc.) and given to the child to drink. You can drink the suspension as desired.

The dosage of the suspension for use for various conditions in children is the same and depends only on body weight. The dosage is calculated individually each time according to the ratio of 0.25 - 0.5 ml of suspension for every 1 kg of the child’s body weight. The calculated amount of suspension is given to the child 3-4 times a day before meals and, if necessary, before bedtime.

However, since the bottle comes with a convenient measuring syringe, which simultaneously indicates the child’s weight options in increments of 1 kg and the corresponding amount of suspension in ml, you don’t have to calculate the dosage for the baby. Simply use the included measuring syringe.

The maximum permissible daily dosage of Motilium suspension for children under 5 years of age is 2.4 ml per 1 kg of body weight, but not more than 80 mg (80 ml of suspension).

If necessary, the suspension can be taken by adults and adolescents over 12 years of age in a dosage of 10–20 ml 3–4 times a day. The maximum permissible daily dose of the suspension for adults and adolescents over 12 years of age is 80 ml.

Each time before use, shake the bottle of suspension and then open it according to the following algorithm:
1. Press the lid on top while turning it counterclockwise;
2. Remove the cover;
3. Remove the measuring syringe from the package and lower it into the bottle so that its tip extends 1–3 cm into the suspension;
4. Holding the lower ring of the syringe with your fingers, raise the piston to the mark that corresponds to the weight of the child;
5. Hold the syringe by the lower ring and remove it from the bottle;
6. Squeeze the suspension into a spoon or other container;
7. Rinse the syringe well with warm water after use;
8. Close the bottle.

special instructions

Motilium should not be used to relieve or prevent postoperative vomiting.

In case of renal failure, it is recommended to maximally increase the intervals between two subsequent doses of the drug, but there is no need to reduce the dosage. However, if a person suffering from renal failure must take Motilium for a long time, then the entire daily dosage should be divided into 1 - 2 doses, and not 3 - 4. If during the use of the drug, kidney function worsens, then it is necessary to reduce the dosage of the drug.

In case of liver failure, the drug in any form should be used with caution, constantly monitoring the functions and condition of the liver.

When using Motilium simultaneously with antacid drugs (Rennie, Phosphalugel, Almagel, Maalox, etc.) and H2-histamine blockers (Ranitidine, Famotidine, etc.), their intake should be spaced out over time. It is optimal to take Motilium before meals, and antacids and H2-histamine blockers after meals.

The coated tablets contain lactose and should not be taken by people suffering from lactose intolerance or glucose and galactose malabsorption. Also, lozenges should not be taken by people who have an increased risk of developing hyperphenylalaninemia due to their aspartame content.

In children under 1 year of age, Motilium can in rare cases provoke neurological side effects, therefore, when using the drug, you should strictly adhere to the recommended dosages, without increasing them yourself.

Use during pregnancy and breastfeeding

During pregnancy, Motilium can be taken only if the expected benefit to the mother outweighs the possible risks to the fetus. Motilium should not be taken while breastfeeding, since the drug is found in milk in a concentration that is 50% of that in the blood.

Impact on the ability to operate machinery

Motilium does not affect a person’s ability to control machinery, therefore, while using the drug, you can engage in any type of activity that requires high concentration and reaction speed.

Overdose

An overdose of Motilium is possible and is manifested by the following symptoms:
  • Disorientation;
  • Agitation (excitement);
  • Altered consciousness;
  • Extrapyramidal reactions (tremor, speech impairment, tics, myoclonus, etc.).
To treat an overdose, a single gastric lavage is performed followed by administration of a sorbent (activated carbon, Polysorb, Polyphepan, etc.). In the future, if necessary, antihistamines and cholinergic drugs, drugs for the treatment of parkinsonism are used to relieve extrapyramidal reactions.

Interaction with other drugs

Anticholinergic drugs (Aprofen, Atropine, Scopolamine, Dicyclomine, Cyclizine, Benactizine, etc.), Cimetidine and sodium bicarbonate reduce the severity of the therapeutic effect of Motilium. The effect of Motilium is enhanced by Fluconazole, Itraconazole, Ketoconazole, Coriconazole, Clarithromycin, Erythromycin, Amprenavir, Atazanavir, Fosamprenavir, Indinavir, Nelfinavir, Ritonavir, Saquinavir, Diltiazem, Verapamil, Amiodarone, Aprepitant, Nefazodone and Telithromycin.

Ketoconazole and Erythromycin, when used simultaneously with Motilium, cause changes in the ECG, which normalize after discontinuation of the drugs.

Side effects of Motilium

The suspension and both types of Motilium tablets can cause the same following side effects on various organs and systems:
1. Gastrointestinal tract:
  • Intestinal spasms;
  • Changes in the activity of AST, ALT and ALP;
  • Thirst;
  • Loss of appetite.
2. Nervous system:
  • Extrapyramidal syndrome (tics, tremors, speech impairment, Parkinson-like movements, muscle tone disorders, etc.);
  • Convulsions;
  • Drowsiness;
3. Mental disorders:
  • Agitation (excitement);
4. The immune system:
  • Anaphylactic reactions (Quincke's edema, anaphylactic shock, urticaria);
  • Allergic reactions.
5. Endocrine system:
  • Increased levels of prolactin in the blood;
  • Galactorrhea (leakage of milk from the breast);
6. Skin:

Extrapyramidal disorders, as a rule, occur in children, but are transient, that is, they disappear on their own after stopping taking Motilium and do not require special treatment.

Contraindications for use

The suspension and both types of Motilium tablets are contraindicated for use if a person has the following diseases or conditions:
  • Prolactinoma (tumor of the pituitary gland of the brain that produces prolactin);
  • Hyperprolactinemia (increased levels of prolactin in the blood);
  • Concomitant use of drugs containing ketoconazole, erythromycin, fluconazole, voriconazole, clarithromycin, amiodarone or telithromycin as active substances;
  • Gastrointestinal bleeding;
  • Mechanical intestinal obstruction;
  • Perforation of any organ of the digestive tract;
  • Body weight less than 35 kg (for tablets);
  • Individual sensitivity or intolerance to the components of the drug;
  • Pregnancy and breastfeeding.
In children under 1 year of age, Motilium should be used only in suspension form and with caution.

Motilium - analogues

Motilium has analogues and synonyms on the pharmaceutical market. Synonyms are products containing, like Motilium, domperidone as an active substance. Analogues are medicines containing other active substances, but having the most similar spectrum of therapeutic action.

The following drugs are synonyms for Motilium:

  • Damelium tablets;
  • Domet tablets;
  • Domperidone, Domperidone Hexal and Domperidone-Teva tablets;
  • Domstal tablets;
  • Motiject tablets;
  • Motilak lozenges and film-coated tablets;
  • Motinorm syrup and tablets;
  • Motonium tablets;
  • Passazhiks tablets are chewable and coated.
The following drugs are analogues of Motilium:
  • Aceclidine solution for subcutaneous injection;
  • Ganaton tablets;
  • Dimetpramide tablets and solution for intramuscular injection;
  • Itomed tablets;
  • Itopra tablets;
  • Melomide hydrochloride tablets and solution for intravenous and intramuscular injections;
  • Metoclopramide tablets and solution for intravenous and intramuscular injections;
  • Metoclopramide-Acri tablets;
  • Metoclopramide-Vial, Metoclopramide-Promed, Metoclopramide-ESCOM solution for intravenous and intramuscular injections;
  • Perinorm tablets, oral solution and solution for intravenous and intramuscular injections;
  • Ceruglan tablets and solution for intravenous and intramuscular injections;
  • Cerucal tablets and solution for intravenous and intramuscular injections.

Cheap analogues

Among the synonyms of Motilium, the cheapest drugs are the following:
  • Domet – 76 – 108 rubles;
  • Domperidone – 99 – 113 rubles;
  • Passengers – 84 – 107 rubles;
  • Motilak – 126 – 232 rubles;
  • Motonium – 94 – 100 rubles.
Among Motilium analogues, the cheapest drugs are the following:
  • Dimetpramid – 89 – 168 rubles;
  • Metoclopramide 35 – 135 rubles;
  • Perinorm 99 – 183 rubles;
  • Tseruglan 19 – 42 rubles;
  • Cerucal 125 – 142 rubles.

Russian analogues of Motilium

Synonyms and analogues of Motilium produced by Russian pharmaceutical factories are given in the table.

Reviews

Reviews of the use of Motilium in adults are in most cases positive, which is due to the high effectiveness of the drug when taken as indicated. However, not everything is clear in the reviews and there are a large number of nuances, since the range of conditions for which people took Motilium is quite wide and varied.

So, adults took Motilium in two main cases. Firstly, the drug was taken occasionally to relieve nausea and vomiting that occurred due to existing diseases of the digestive tract, dietary disorders or infectious disease. Secondly, adults took Motilium as part of complex therapy for stomach diseases (gastritis, peptic ulcers, pyloric stenosis, etc.), reflux and GERD in order to relieve flatulence, a feeling of fullness in the epigastrium, belching, early satiety, vomiting and other symptoms of the disorder digestion of food characteristic of these diseases.

When taking Motilium occasionally to relieve vomiting and nausea, the drug eliminates these symptoms in approximately 2/3 of cases after the first tablet. Relieving vomiting and nausea significantly improves a person’s overall well-being, allowing him to calmly drink various solutions to replenish fluid loss, as well as take other medications whose action is aimed at eliminating the cause of symptoms and treating the disease. In such situations, reviews of Motilium were positive.

In the remaining 1/3 of cases, people had to take Motilium to stop vomiting for several days in a row before each meal or liquid. This mode of use of the drug, of course, does not please people, so in such situations, as a rule, they leave neutral or negative feedback.

And when taking Motilium to relieve dyspeptic symptoms (belching, nausea, vomiting, flatulence, feeling of fullness in the stomach, epigastric pain, etc.), characteristic of chronic stomach diseases, GERD and reflux, the drug was effective in almost 100% of cases, Therefore, this category of reviews about him is almost all positive.

Motilium for children - reviews

Currently, there is a very interesting situation when, in practice, Motilium is used in children for a wide range of different conditions, and very often not according to indications, but according to one’s own ideas about the physiological functions of the child’s body. Naturally, in such a situation, reviews of Motilium are very varied. To get your bearings, let’s look at the reviews of people who gave the drug to a child for various reasons.

Reviews of the use of Motilium to relieve vomiting in children with rotavirus infections, any other acute infectious diseases, as well as in response to medications are positive in approximately 2/3 of cases. This is due to the fact that the drug stopped vomiting and improved the general condition of the child, who began to actively play, ask to drink, eat, etc. Moreover, in some cases, to stop vomiting, a single dose of the drug was enough, and in others, it was necessary to give the child syrup several times a day for 2–3 days. When vomiting did not stop after a single dose of the drug, the parents gave Motilium to the child before each meal, drink, or other medication.

Approximately 1/3 - 1/4 of the reviews about Motilium for the relief of vomiting in acute conditions in children are negative, which, as a rule, is due not so much to the properties of the drug as to a subjective attitude towards it, inflated expectations, as well as off-label use. Very often, parents try to give their child Motilium for vomiting caused by poisoning, and when the drug does not have the expected effect, they become disappointed and leave negative feedback. In fact, Motilium will not stop vomiting in case of poisoning, since it is caused by the entry of toxic substances into the blood from the intestines, and not by a disorder of the stomach. In such cases, you need to take sorbents that bind toxic substances. And Motilium can be drunk only before taking the sorbent, so that the child does not vomit within the next 10 - 15 minutes and the main therapeutic drug is not expelled.

The second part of the Motilium reviews concerns its use in infants and young children to reduce gas formation, bloating and regurgitation. In this case, almost all reviews about the drug are positive, since the syrup effectively relieved these symptoms.

The third part of the reviews about the drug concerns its use in diseases of the digestive tract in children (GERD, gastritis, gastroduodenitis, esophagitis, reflux) in order to relieve the unpleasant symptoms of slow gastric emptying (feelings of heaviness in the stomach, abdominal pain, belching, flatulence, nausea, vomiting and etc.). This category of reviews is in most cases positive, since parents achieve a good therapeutic effect with regular use of Motilium syrup according to the instructions.

The fourth part of the reviews about Motilium concerns its off-label use. So, many parents give syrup to their children so that food is evacuated from the stomach faster, and they can eat more at a time. This use of syrup is based on the fact that Motilium relieves the feeling of fullness in the stomach. Typically, the drug is used in this way when trying to get a child to “eat well” and gain weight, which, according to parents and doctors, is insufficient. Naturally, this method of improving a child’s appetite and increasing the amount of food he eats does not work for a number of reasons, and parents leave negative feedback about the drug.

Firstly, Motilium reduces the feeling of fullness in the stomach and accelerates the passage of the food bolus into the intestines only in diseases such as peptic ulcers, gastritis, GERD, esophagitis and reflux! And if the child does not suffer from such diseases, then food is evacuated from the stomach into the intestines at a normal speed, and attempts to reduce this period of time only lead to the fact that the food bolus is poorly processed and digested by gastric juice. This will cause colic, flatulence, bloating and other unpleasant sensations in the baby. In other words, trying to speed up the evacuation of the food bolus from the stomach into the intestines, so as to “free up” space for another large portion of food, parents only disrupt the child’s normal digestion process, which can ultimately cause the development of severe chronic gastrointestinal diseases.

Secondly, while taking Motilium, the child will not be able to eat more, but, on the contrary, will be satiated with less food. This is due to the fact that the bolus of food will quickly enter the intestines, from where nutrients will begin to be absorbed into the blood and give a signal to the brain about the onset of satiety. As a result, the child will be satisfied with much less food than before.

That is, the use of Motilium in order to “improve” a child’s nutrition is not only irrational, inappropriate, ineffective and not according to indications, but also dangerous. In order for a child to gain weight, you need to feed him small portions of high-calorie and tasty food 4 to 6 times a day. And trying to feed him a large portion of low-calorie food only stretches the stomach, disrupts the normal digestion process and creates the basis for the development of gastrointestinal diseases.

Ganaton or Motilium?

Ganaton is a prokinetic drug, that is, it improves the motor functioning of the stomach, accelerating the evacuation of its contents and, thereby, relieving the painful symptoms associated with food retention in it (heartburn, belching, flatulence, a feeling of fullness and pain in the stomach, etc. .). And Motilium can be used for the same conditions as Ganaton, but in addition also to stop vomiting. That is, the range of indications of Motilium overlaps that of Ganaton. However, the effectiveness of Ganaton is 10% higher compared to Motilium.

This means that to relieve painful symptoms (nausea, vomiting, heartburn, belching, feeling of fullness and epigastric pain, etc.) of diseases of the stomach and esophagus (gastritis, esophagitis, GERD, peptic ulcer, etc.), you can use both Ganaton and and Motilium. However, Ganaton is preferable in such situations, since this drug is intended specifically for use in the complex treatment of these conditions.

Ganaton is also preferable in cases where it is necessary to take drugs for a long period of time or together with other medications. This is usually necessary in the treatment of chronic diseases of the stomach and esophagus.

For episodic relief of symptoms of dyspepsia (heartburn, belching, vomiting, nausea, feeling of fullness in the stomach, pain in the epigastrium after eating, etc.), arising from a diet violation or for other reasons, you can use any drug that for any reason reasons a person likes it more.

To relieve vomiting and nausea caused by taking any medications, infections, gastrointestinal diseases and functional digestive disorders, you should choose Motilium, since Ganaton is ineffective in such situations.

Motilium should also be chosen if it is necessary to use drugs with similar properties in children, since Ganaton cannot be used to treat children.

Motilium or Motilak?

Motilium and Motilak are synonyms, that is, they contain exactly the same active ingredient domperidone. From the point of view of therapeutic effects, Motilak and Motilium do not differ from each other, however, the first drug causes side effects somewhat more often.

Thus, in the absence of any special requirements for the drug, as well as with general good tolerability of the drugs, when side effects occur rarely, you can choose any drug - Motilak or Motilium, based only on subjective preferences (for example, for some reason one drug is liked more than another, relatives or friends respond positively). If a person is prone to developing side effects or does not tolerate any medications well, then Motilium should be preferred.

However, Motilium is available in tablets and suspensions, while Motilak is available only in tablets. Therefore, Motilak cannot be used for children, but Motilium can. That is, if it is necessary to use the drug in children or in people who for some reason find it difficult to swallow tablets, Motilium should be preferred. If a person can take pills, then you can choose any remedy based on your own subjective preferences.

Motilium (tablets and suspension) – price

The cost of various dosage forms of Motilium varies in pharmacies in Russian cities within the following limits:
  • Suspension 1 mg/ml, bottle 100 ml – 485 – 672 rubles;
  • Lozenges 10 mg, 10 pieces – 345 – 458 rubles;
  • Lozenges 10 mg, 30 pieces – 550 – 701 rubles;
  • Coated tablets 10 mg, 30 pieces – 452 – 589 rubles.
Before use, you should consult a specialist.