Furadonin tablets instructions for use in adults. What does furadonin help with?

"Furadonin" is a synthetic drug, an antimicrobial agent. It has a broad spectrum of action, the main active ingredient of which is a nitrofuran derivative - nitrofurantoin.

Nitrofurantoin has a bactericidal and bacteriostatic effect in inflammatory processes of the genitourinary system. It is well excreted from the gastrointestinal tract, completely excreted by the kidneys, and is also excreted in breast milk, so it is not recommended to take it during lactation.

"Furadonin" is produced in 0.05 g and 0.1 g in a package of 20 pieces, as well as in the form of intestinal soluble tablets (this form is provided) with a dosage of 0.03 g, 30 pieces in a package.

Indications for use of the drug

"Furadonin" is prescribed in the presence of infections of the genitourinary system, pyelonephritis, pyelitecystitis, inflammatory diseases of the genitourinary system, as well as to prevent infections during diagnostic studies, such as catheterization, cystoscopy, and various surgical interventions.

Directions for use and doses

In order to prevent infectious diseases, 1 (0.05 or 0.1 g) tablet of "Furadonin" is prescribed per day. For mild infections, take half a tablet 3 times a day. For severe exacerbations, chronic and severe infections, 1 tablet 3-4 times a day. The drug is prescribed with caution to children aged three years and older. For them, the dosage of the drug is 3 mg per 1 kg of body weight for four doses per day. The duration of one course of treatment is 7 days. If the result is insufficient, treatment can be continued for up to 10 days. With long-term use of the drug as maintenance (preventive) therapy, the dose of nitrofurantoin should be gradually reduced.

Furadonin should be taken together with prebiotics and food products that support normal intestinal microflora.

The drug should be taken only in the dosage specified in the instructions.

Side effects

Taking Furadonin can cause a number of side effects from the respiratory system, digestive system, central nervous system, and peripheral nervous system. For example, quite often patients using furadonin complain of chest pain, difficulty breathing, coughing, and attacks of bronchial asthma in patients with a history of asthma. Dyspnea, pulmonary infiltrates, pneumonitis, fibrosis, and eosinophilia are also possible. Common side symptoms include nausea, vomiting, diarrhea, anorexia, stomach discomfort, and abdominal pain. To avoid nausea, experts advise drinking Furadonin with plenty of water. Or you will have to wait until the end of the course of treatment.

It is necessary to take Furadonin before meals with a sufficient amount of water.

Sometimes patients while taking the drug may experience headaches, migraines, drowsiness, increased intracranial pressure, various allergic reactions: urticaria, rash, skin itching, Quincke's edema, in isolated cases - anaphylactic shock, dermatitis and other side effects. Among them are flu-like symptoms, arthralgia, and superinfection of the genitourinary tract, the development of which is provoked by Pseudomonas aeruginosa.

As a rule, specialists involved in the development and research of a particular drug play it safe by listing as side effects all possible reactions of the body to the active substance of the drug - up to one case per 100 thousand people. Therefore, it is difficult to predict exactly whether you will develop hives, an allergy to a medicine or not. But if you already have a history of allergic reactions, bronchial asthma and other diseases in which adverse reactions may occur, you should warn your doctor about them, just in case. If necessary, he will select the most suitable analogue for you. But it is worth remembering that the active ingredient of analogues of this drug is the same nitrofurantoin. Therefore, the appearance of the above side effects also occurs during treatment with other drugs.

Contraindications to the use of the drug

"Furadonin" is not recommended for use by people with severely impaired renal excretory function, hypersensitivity to nitrofurantoin, people suffering from heart failure, chronic hepatitis, liver cirrhosis, porphyria, diabetes mellitus. Taking "Furadonin" by pregnant women and during lactation is prohibited, as it has a serious effect on the microflora of the mother's body, and, accordingly, on the child. Given the complexity of side effects, the drug is not prescribed to children in the first years of life. When the child reaches three years of age, the drug is prescribed in accordance with the recommended doses. In this case, constant monitoring of the patient's condition is necessary.

Caution should be used when prescribing Furadonin to patients with anemia, electrolyte imbalance, severe renal failure, or deficiency of B vitamins in the body. In this case, the risk of developing peripheral neuropathy significantly increases. Treatment with Furadonin should not be prescribed for prostatitis and purulent paranephritis.

Furadonin is a drug with antimicrobial and bactericidal action, which is widely used in the treatment of infections of the urinary system.

By disrupting the permeability of the cell membrane and protein synthesis in bacteria, it has a bacteriostatic and bactericidal effect. Highly active against gram-negative and gram-positive bacteria, such as Streptococcus spp., Staphylococcus spp., Salmonella paratyphi A, Salmonella typhi, Salmonella paratyphi B, Escherichia coli, Enterobacter spp., Proteus, Shigella sonnei.

The high effectiveness of Furadonin is caused by a violation of the biosynthesis of proteins in ribosomes, as well as a direct effect on the cytoplasmic membrane of the infectious agent. During treatment, bacterial resistance rarely develops, but it can occur with long-term use of the drug.

The drug is active against most pathogens of inflammatory processes in the kidneys, bladder and urethra, such as Escherichia coli, streptococcus, Klebsiella, staphylococcus, etc.

The activity of the active substance directly depends on the acidity of the urine - in an alkaline environment it is significantly reduced.

Indications for use

What does Furadonin help with? The drug is prescribed in the following cases:

• treatment of infectious and inflammatory diseases of the urinary tract (pyelonephritis, pyelitis, cystitis, urethritis),
• as a prophylactic agent for cytoscopy, urological operations, catheterization.

Instructions for use of Furadonin and dosage

Adults are prescribed 0.1-0.15 g of Furadonin 3-4 times a day. Maximum therapeutic dosage for adults: daily – 0.6 g, single – 0.3 g. The course of treatment for acute urological infections is 7-10 days.

Anti-relapse and preventive treatment can last from 3 to 12 months (depending on the nature of the disease), in such cases the daily dosage is 1-2 mg/kg.

For cystitis, the antibiotic Furadonin should be taken in the following dosages:

• 50–100 mg 3-4 times daily for adults;
• 100 mg 2 times a day for children over 12 years of age;
• 5–8 mg per kg body weight 4 times daily for children under 12 years of age.

There should be equal intervals between taking tablets. A missed or late dose of an antibiotic reduces its effectiveness.

Children are prescribed at the rate of 5-8 mg/kg per day, the daily dosage is divided into 4 doses.

Side effects

Prescription of Furadonin may be accompanied by the following side effects:

• nausea, vomiting, allergic reactions,
• dizziness, headache, asthenia, nystagmus, drowsiness,
• broncho-obstructive syndrome, fever, cough, chest pain,
• peripheral neuropathy,
• pancreatitis, hepatitis, cholestatic syndrome,
• pseudomembranous enterocolitis,
• rarely – abdominal pain, diarrhea.

The drug is incompatible with fluoroquinolones. Drugs that block tubular secretion, by reducing the concentration of nitrofurantoin in the urine, reduce the antimicrobial effect of Furadonin and increase its toxicity (due to an increase in its concentration in the blood).

Contraindications

It is contraindicated to prescribe Furadonin in the following cases:

• hypersensitivity to the drug and other nitrofurans;
• renal failure;
• heart failure (II, III degrees);
• cirrhosis of the liver;
• chronic hepatitis; porphyria;
• pregnancy (since there is a risk of the child developing hemolytic anemia);
• lactation;
• age up to 1 month.

Overdose

A symptom of an overdose is vomiting.

Analogues of Furadonin, list of drugs

If necessary, you can replace Furadonin with an analogue of the active substance - these are the following drugs:

1. Nitrofurantoin.

Similar drugs:

• Nifuroxazide-lf
• Nifuroxazide-Rn
• Stopdiar
• Stopdiar
• Stopdiar
• Stopdiar
• Furagin
• Furazidin

When choosing analogues, it is important to understand that the instructions for use of Furadonin, price and reviews do not apply to drugs with similar effects. It is important to consult a doctor and not change the drug yourself.

Price of Furadonin 50 mg tablets in pharmacies (Moscow): 64 – 93 rubles (10-20 pieces)

The drug is stored in a dark, dry place at a temperature below 25 degrees Celsius.

Furadonin has a pronounced bacteriostatic and bactericidal effect in urinary tract infections, and is an inexpensive drug for the treatment of bacterial cystitis (both acute and exacerbation of chronic).

In addition, it can be taken for chronic inflammation of the bladder to prevent relapses. Effective against gram-positive and gram-negative bacteria (staphylococci, streptococci, dysentery bacillus, E. coli, Proteus).

In this article we will look at why doctors prescribe Furadonin, including instructions for use, analogues and prices for this drug in pharmacies. Real REVIEWS of people who have already used Furadonin can be read in the comments.

Composition and release form

The release form in the pharmacy is tablets for adults, 0.05 g and 1 mg, for children, 0.03 g, a special suspension with a dosed spoon. As a rule, a prescription is not required to purchase.

• The active ingredient is nitrofurantoin in a dosage of 50 mg or 100 mg;
• Auxiliary ingredients are aerosil, potato starch, calcium stearate and others.

Pharmacological action: the medicine belongs to the group of nitrofurans, it is an antimicrobial drug.

What does Furadonin help with?

Furadonin is prescribed for infectious and inflammatory diseases of the urinary tract, such as:

• pyelonephritis,
• cystitis,
• pyelitis,
• urethritis.

Furadonin is used as a prophylactic drug during urological operations, cytoscopy, catheterization.

pharmachologic effect

The medicine is intended mainly for the treatment of urinary tract infections. The properties of Furadonin are due to its ability to disrupt the synthesis of protein molecules in the bacterial cell. The drug is active against staphylococci, streptococci, Shigella, Escherichia, Proteus and a number of other microorganisms.

Furadonin is well absorbed from the gastrointestinal tract. Penetrates through the blood-brain barrier (into brain tissue), the placenta and is able to be excreted in breast milk.

Instructions for use

For those who use Furadonin, the instructions for use indicate that it should be taken orally after meals with plenty of liquid. If a dose of Furadonin is missed, it is necessary to continue treatment according to the previously prescribed regimen.

• The dose for adults is 50-100 mg, the frequency of use is 4 times a day.
• The daily dose for children is 5-7 mg/kg in 4 divided doses.
• The duration of treatment is 7 days.
• For preventive purposes, Furadonin is taken 100 mg/day (at night).

If necessary, it is possible to continue treatment for another 3 days (only after checking the urine for sterility). During long-term maintenance treatment, the dose of nitrofurantoin should be reduced.

Furadonin: instructions for use for cystitis

The treatment regimen is prescribed individually in each case. For cystitis, the antibiotic Furadonin is recommended to be taken in the following dosages:

• 50–100 mg 3-4 times daily for adults;
• 100 mg 2 times a day for children over 12 years of age;
• 5–8 mg per kg body weight 4 times daily for children under 12 years of age.

There should be equal intervals between taking tablets. A missed or late dose of an antibiotic reduces its effectiveness. During treatment, it is necessary to increase the total amount of fluid consumed per day.

Contraindications

This antibacterial medicine should not be taken in the following cases:

• in case of allergic reactions to its components;
• for acute or chronic liver failure;
• in case of renal failure with a creatinine index above 60 ml per minute;
• during pregnancy and during breastfeeding;
• with acute porphyria;
• with cirrhosis of the liver;
• if the patient is on hemodialysis;
• for chronic heart failure of 2nd and 3rd degree.

Side effect

It should be noted that Furadonin can have side effects on various body systems.

Nervous system:

• drowsiness,
• dizziness,
• headache,
• peripheral neuropathy.

Digestive system:

• nausea,
• vomit,
• lack of appetite,
• gastrointestinal disorders.

Allergic reactions:

• skin rashes,
• Quincke's edema,
• anaphylactic shock.

Respiratory system:

• chest pain,
• dyspnea,
• cough,
• attacks of bronchial asthma

Circulatory system:

• decrease in the volume of leukocytes and platelets,
• development of anemia.

Side effects sometimes cause negative reviews of Furadonin from patients, however, when using the drug according to the instructions and under medical supervision, it is quite well tolerated, and mild side effects do not require discontinuation of the drug.

Use during pregnancy

The drug should not be prescribed to patients during breastfeeding or during pregnancy. If Furadonin therapy is necessary during lactation, the issue of stopping breastfeeding should be decided, since the drug can have a negative effect on the baby.

Analogs

The main active ingredient of Furadonin is nitrofurantoin, a unique chemical compound; for this reason, the drug has no analogues. There are only drug substitutes with a similar mechanism of action - Furamag, Furazidin, Furagin, Furazolidone, Furacilin.

Despite the fact that they are all included in the group of nitrofurans, it is not recommended to change one drug to another on your own; it is better to consult with your doctor.

Furadonin is a drug from the nitrofuran group that disrupts the permeability of the cell membrane and protein synthesis in bacteria, providing a bactericidal, bacteriostatic effect.

This drug is effective for the treatment of diseases of the genitourinary system, as it accumulates in high concentrations in the urine and is excreted by the kidneys. Well tolerated with short-term use. The therapeutic effect develops quite quickly and persists for a long time. Indicated for the development of infectious lesions of the prostate in men and the symptomatic treatment of STIs.

The drug is well absorbed from the gastrointestinal tract, penetrates the placenta and into breast milk, cerebrospinal fluid, and is excreted by the kidneys. May give urine a dark color. Blood concentrations at usual therapeutic doses are insignificant.

Clinical and pharmacological group

Broad-spectrum antimicrobial agent, nitrofuran derivative.

Terms of sale from pharmacies

Can buy without a doctor's prescription.

Price

How much does Furadonin cost in pharmacies? The average price is 110 rubles.

Composition and release form

The drug is produced in the form of tablets, suspension and powder for internal use. The tablets are coated with a coating that dissolves in the intestines. The package contains 12, 20, 30, 40 or 50 tablets.

• Furadonin contains the active ingredient nitrofurantoin; the tablets also contain colloidal silicon dioxide, potato starch, and calcium stearate.

Pharmacological effect

Furadonin is a broad-spectrum antimicrobial agent, a derivative of nitrofuran, but is not included in the group of antibiotics. Due to the active substance, the drug has a bactericidal and bacteriostatic effect against urinary tract infections. The medicine destroys bacterial membranes, inhibits protein synthesis, destroys E. coli, Klebsiella, Enterobacteriaceae, Proteus, and Staphylococcus. The product is well absorbed by the digestive tract, its bioavailability increases with food intake.

According to the instructions, the rate of absorption of the antibacterial agent depends on the size of the crystals (the powder dissolves faster, is absorbed, and concentrates in the urine as quickly as possible). The substance binds to plasma proteins by 60%, is metabolized by the liver and muscle tissue, the half-life is 20-25 minutes. Nitrofurantoin penetrates the placental and blood-brain barriers and is excreted by the kidneys.

Indications for use

Furadonin is used for the treatment and prevention of infectious and inflammatory diseases of the urinary tract (caused by pathogens sensitive to the drug):

• pyelitis;
• pyelocystitis;

For prophylactic purposes, Furadonin is prescribed for cystoscopy (examination of the bladder using an optical cystoscope), bladder catheterization (insertion of a special rubber tube - catheter) into the bladder, and during urological operations.

Contraindications

According to the instructions for Furadonin, this drug is contraindicated for:

• acute porphyria;
• glucose-6-phosphate dehydrogenase deficiency;
• pregnancy, lactation;
• hypersensitivity to nitrofurantoin;
• chronic heart failure;
• chronic renal failure;
• liver cirrhosis;
• chronic hepatitis;
• up to 1 month of age.

Prescription during pregnancy and lactation

Considering the fact that Furadonin crosses the placenta and can have a toxic effect on the fetus, it is contraindicated to take it during pregnancy.

Experimental studies in animals have shown a risk to the fetus. Clinical experience with the use of Furadonin during pregnancy has not been studied.

Gynecologists sometimes use Furadonin in the treatment of urinary tract infections in women after 12 weeks of pregnancy. In this case, it is necessary to compare the possible risk to the fetus and the therapeutic effect of using Furadonin.

Dosage and method of administration

As indicated in the instructions for use, Furadonin tablets are intended for oral administration as an independent bacteriostatic agent or as part of complex therapy for the treatment of urinary tract diseases caused by microorganisms sensitive to nitrofurans. The dose of the drug and the duration of the course of treatment are determined by the doctor individually for each patient.

According to the instructions, adult patients and children over 12 years of age are prescribed 50-100 mg of the drug 4 times a day. For children under 12 years of age, a single dose of the drug is calculated based on weight indicators - 5 mg/kg body weight. The duration of the course of drug therapy is 3-5 days; if necessary, treatment can be extended up to 14 days under the supervision of a physician. If during this period the patient does not experience any improvement in his condition or, on the contrary, deterioration is visible, then he should stop taking the pills and consult a doctor.

Adverse reactions

The following adverse reactions were observed during treatment with Furadonin:

1. Drowsiness.
2. Pancreatitis, hepatitis, enterocolitis.
3. Diarrhea, abdominal pain.
4. Vomiting, nausea.
5. Shortness of breath, broncho-obstructive syndrome, cough.
6. Chills, fever.
7. Pain in muscles and joints.
8. Skin rash.
9. Cholestatic syndrome.
10. Changes in blood parameters.

With renal failure, the risk of developing peripheral neuropathy increases.

Often, when treating Furadonins, diarrhea occurs, which is caused by clostridia. The fact is that the drug is able to change the balance of microflora in the intestines, promoting the growth and reproduction of this type of bacteria. If such a symptom appears, treatment is stopped.

Overdose

When taking Furadonin orally in high doses, the patient may develop signs of overdose, which are clinically expressed in an increase in the above-described side effects, impaired functioning of the kidneys and liver, and the development of liver failure.

Treatment of an overdose of the drug consists of gastric lavage, intravenous administration of enterosorbents to the patient, and symptomatic treatment if necessary.

special instructions

The risk of developing peripheral neuropathy increases in patients with anemia, diabetes mellitus, electrolyte imbalance, B vitamin deficiency, and severe renal failure.

Nitrofurantoin should not be used to treat diseases of the renal cortex, purulent paranephritis and prostatitis. Nitrofurantoin is not prescribed in combination with drugs that cause renal impairment.

Compatibility with other drugs

Nitrofurantoin is incompatible with fluoroquinolones.

The simultaneous use of nalidixic acid and antacids containing magnesium trisilicate reduces the antibacterial effect of nitrofurantoin.

When used simultaneously, drugs that block tubular secretion reduce the antibacterial effect of nitrofurantoin (by reducing the concentration of nitrofurantoin in the urine) and increase its toxicity (increasing the concentration in the blood).

Furadonin tablets – 1 tablet contains nitrofurantoin – 50 mg. Excipients: potato starch, colloidal silicon dioxide, calcium stearate.

A broad-spectrum antimicrobial drug based on the active substance of a nitrofuran derivative. The tablets have a bacteriostatic and bactericidal effect against urinary tract infections. Furadonin actively suppresses gram-positive and gram-negative bacteria of the species Escherichia coli, Klebsiella spp. , Enterobacter spp. , Proteus spp.

Indications:

Bacterial urinary tract infections (pyelitis, pyelonephritis, cystitis, urethritis), prevention of infections during urological operations or examinations. Due to its effectiveness and price, the use of furadonin 50 mg is quite widespread; most often, tablets are prescribed for the treatment of cystitis in women.

Furadonin for cystitis - instructions for use

The body absorbs furadonin very easily and the “working” concentration of the active substance in the urine is achieved within an hour. At the same time, the level of its concentration in the blood is quite insignificant. Due to their good solubility in biological fluids, the tablets give the urine a darker color; there is no need to be alarmed by this.

How to take furadonin for cystitis? According to the instructions for use of the drug, adults take 100-150 milligrams four times a day. The highest daily dose for adults is 600 milligrams, a single dose is 300 milligrams. A specific dosage of furadonin should be prescribed by a urologist after an appropriate examination and determination of the type of bacteria.
The standard course of treatment for cystitis and other urinary tract infections is 7-10 days.

If necessary, the doctor can continue therapy for a few more days (only after a control urine test). During long-term maintenance treatment, the dose of nitrofurantoin should be reduced.

Treatment with furadonin is especially effective in the early stages of cystitis, when the first signs of bladder inflammation appear. Complex therapy is used to treat chronic forms.

It is possible to use the medicine for preventive purposes - the dosage should not exceed 10 mg per day. It is best to drink at night, after the “last” toilet. Anti-relapse and preventive treatment can last from 3 to 12 months (depending on the type and form of the disease).

For a child under 12 years of age, the use of furadonin avexima 50 mg tablets is possible in doses of up to 7 mg/kg body weight per day (maximum!), and the daily dose is divided into four doses.

Over 12 years old – 100 mg 2 times a day.

How many furadonin tablets should I take? This question will best be answered by a doctor after tests; the recommended doses are listed above. Furadonin receives numerous positive reviews for cystitis from a large number of patients, especially women, but you should not abuse the medicine. Remember that this is an antibiotic, albeit a narrow-spectrum one.

The instructions for use of furadonin require that when using the drug there are equal intervals between doses. A missed or late dose of an antibiotic reduces its effectiveness. It is recommended to increase the total amount of liquid you drink per day and take the tablet with plenty of clean water.

furadonin avexima 50 mg is not prescribed for the treatment of purulent paranephritis, prostatitis and pathology of the renal cortex.

Use of Furadonin tablets during pregnancy and lactation

During pregnancy, taking Furadonin increases the risk of developing hemolytic anemia in the newborn. It can be used in the last trimester with extreme caution and only as prescribed by a doctor. The use of Furadonin in the first 12 weeks, when the main vital organs of the embryo are formed, is absolutely excluded.

It is better not to use Furadonin during pregnancy, especially not to self-medicate.

Furadonin passes into breast milk, during lactation, and also for children under 1 month of age, the drug is also contraindicated.

Side effects of Furadonin

In case of an overdose of the drug, vomiting and dizziness occur. It is recommended to drink more water to speed up the removal of the active substance from the body.
Medicines belonging to the nitrofuran group can cause the following side effects:

• allergic reactions,
• nausea,
• vomit,
• headache and dizziness,
• drowsiness,
• fever,
• dyspnea,
• chest pain and cough,
• hives;
• Quincke's edema,
• skin itching,
• rash,
• anaphylactic shock (very rare),
• drug fever,
• arthralgia,
• flu-like symptoms are possible.

While taking the drug, cholestatic syndrome and pseudomembranous enterocolitis may develop. Signs of pancreatitis and hepatitis appear. Interstitial changes in the lung tissue develop. Sometimes peripheral neuropathy and broncho-obstructive syndrome occur (treatment must be stopped!).

Side effects sometimes cause negative reviews of Furadonin from patients, however, when using the tablets according to the instructions and under the supervision of a physician, the drug is quite well tolerated, and mild forms of side effects do not require discontinuation of treatment with Furadonin.

Analogues of Furadonin, list of drugs

Antibacterial drugs, analogues of Furadonin (nitrofuran derivatives) list:

• Furagin;
• Furazidine;
• Furamag;
• Furasol.
• Furadonin avexima

Please note that analogues use the same active ingredient, but these are not exact copies of the drug and their instructions for use are different!

Furadonin contraindications:

Furadonin is contraindicated in persons with hypersensitivity to the drug, chronic renal failure, chronic heart failure stage II - III, liver cirrhosis, chronic hepatitis, acute porphyria, glucose-6-phosphate dehydrogenase deficiency.

Storage conditions:

The drug is stored in a dark, dry place at a temperature below 25 °C.

Release form of the drug:
Tablets in packs of 12, 20, 30, 40, 50 pcs.