HPV type 73 in women treatment. Human papillomavirus

HPV (Human Papilloma Virus) is a virus that causes changes in skin cells and mucous membranes such as warts and condylomas. Abbreviation: HPV (written in tests).

Over the past 50 years, more than 100 types of human papillomavirus have been discovered. Of which 80 species are pathogenic for humans.

The source of the virus is the altered cells of a sick person. At the same time, visually, a sick person may not yet have manifestations on the skin in the form of warts (or condylomas). Despite the fact that there are no visual manifestations and may be microscopic, such a person is contagious and can already transmit the virus to another person.
Previous infection occurs in childhood. On the skin, through abrasions and scratches, the virus enters the body and causes warts in children.

The development of genital warts in adults is caused by certain types of the HPV virus. Sexual transmission mechanism. The virus is transmitted from a sick person to his partner through microtraumas on the mucous membranes.
In most cases, the human immune system is able to overcome this virus itself. The mechanism of action is this: when the virus enters the human body, it encounters cells of the immune system on its way, which in most cases destroy the virus.

If the immune system fails, the virus penetrates the cells of the basal layer of the epithelium of the skin or mucous membranes, then it integrates into the chromosomes of the cells and changes their functioning. As a result, cells begin to rapidly divide and grow in certain areas of the skin, forming warts or condylomas.

Remember:

• types of HPV that cause the formation of warts enter the body in childhood through microdamages of the skin
• types of HPV that cause the formation of condylomas enter the human body mainly through sexual contact

In some cases, human papillomavirus infection in the human body can lead to degeneration into cancer. All types of papillomaviruses are classified according to the degree of possible cancer development.

Classification of HPV by type of oncogenicity

1.Types of papillomavirus that never cause cancer HPV 1.2.3.4.5.10.28.49
2. Types of papillomavirus that have a low oncogenic risk (very rarely causing cancer) HPV 6.11.13.32.40.41.42.43.44.51.72
3. Types of papillomavirus that have an average oncogenic risk of HPV 26.30.35.52.53.56.58.65
4. Types of papillomavirus that have a high oncogenic risk (most often give degeneration) HPV 16.18.31.33.39.45.50.59.61.62.64.68.70.73 All are most common in women.

Percentage incidence of cervical cancer

In 1.73-90% of cases, HPV 16.18 and 45 are found
2. In 77-93% of cases, HPV 16.18.45.31.59 is found
3. In 80-94% of cases, HPV 16.18.45.31.33.59 is found

Also, HPV type 61.62.68.70.73 is combined in precancerous conditions in urology and gynecology.

The most common types of HPV

50% human papillomavirus 16 (spelled HPV 16)
10% human papillomavirus 18 (HPV 18)

Clinic and symptoms

At an early stage, the human immune system is strong enough to overcome the virus on its own at an early stage of development. Months and possibly decades later, people may experience symptoms of HPV infection.

A) WARTS: caused by HPV types – 1.2.3.4.5.10.28.49.
Juvenile (or flat) warts - caused by types 3 and 5 of the virus. These are small flat elevations on the skin that occur mainly in children.

Spikes (or plantar warts) - caused by types 1 and 2 of the virus,
vulgar warts on the fingers - caused by type 2 viruses.

B) Laryngeal papillomatosis. Multiple growths-papillomas on the laryngeal ligament. Sometimes it appears in children born to women with genital warts. Caused by virus type 11.

C) Genital warts on the genitals, in the anus, in the oral cavity and on the lips (types - 6. 11. 13. 16. 18. 31. 35). The main mechanism of transmission in adults is sexual.

D) Bowenoid papulosis. Caused by types – 16. 18. 31. 33. 42. 48. 51. 54. It develops more often in men who constantly change sexual partners. Small, flat wart plaques (somewhat similar to flat warts) appear around the genitals.

D) Cervical intraepithelial neoplasia (or dysplasia) of the cervix and cervical cancer are more serious clinical manifestations of HPV infection in women. The most common manifestations of the malignant course of this infection.

Remember:
Cervical erosion and HPV are FAR from the same thing.
Modern medicine declares with 100% certainty that cervical cancer is caused exclusively by papillomavirus types 16. 18. 31. 33. 35. 39. 40. 42. 43. 55. 57. 59. 61. 62. 66. 67.

E) Bowen's disease - cancer of the skin of the penis. Caused by virus types 16 and 18.

G) Today, some foreign scientists believe that the human papillomavirus is the cause of cancer of any localization. Cancer is a malignant tumor of the epithelium of the skin or mucous membrane, therefore, the HPV virus, which causes dysplastic phenomena in the epithelium, causes the appearance of cancer. And with cervical cancer this has been proven 100%.

Remember:
Any viral infection that is constantly present in the human body (and HPV is one of these) is activated only when immunity decreases.

Diagnostics

1) PCR analysis. The main method for diagnosing papillomavirus is the PCR reaction. The most common types of HPV tests are virus types 16, 18, as well as a number of other highly oncogenic types.

In men - with the mucous membrane of the penis. Material for analysis is taken from the mucous membrane of the woman’s vagina and cervix.
However, the PCR reaction can also give a false result, both a false positive and a false negative result. And this fact does not depend on the complexity of the equipment and the quality of the reagents.

2) Digene test. This test is used to determine the presence of clinically significant concentrations of the virus. Moreover, thanks to this test, it is possible to identify whether viruses have a high or low degree of oncogenicity.
The Digene test is used in conjunction with a cytological examination of the cervix.

3) Examination by a gynecologist, urologist and dermatovenerologist if genital warts or other warts are detected in the groin area.

4) Cytological examination of a smear taken during a gynecological and urological examination.

5) Histological examination of a microscopic piece of tissue. The doctor evaluates the degree of change in the tissue taken for examination.

Treatment

Necessarily!
1. Removal of manifestations - warts, condylomas, dysplasia (erosion) or cervical cancer.
2. Taking antiviral drugs.
3. Strengthening the immune system.

Self-medication can lead to progression!

1) Removal

Removal with chemically aggressive liquids

2) Antivirals
3) Drugs that increase immunity

Remember: First, the doctor must make the correct diagnosis and only he can prescribe the correct treatment for you!

HPV and pregnancy

If papillomavirus infection is detected during pregnancy:
the first thing is to find a gynecologist and be observed by him until the birth,
the most important thing is what manifestations a woman has, the doctor’s tactics will depend on this,
the virus has no effect on the fetus,
during childbirth, the baby can become infected while passing through the birth canal (although this is extremely rare),
in the presence of pronounced manifestations on the cervix, a pregnant woman may be offered a caesarean section,
in the absence of manifestations - natural birth.

HPV prevention

Nature has come up with a wonderful mechanism for healing and prevention for a person, which then helps him not to get sick again. This is the immune system.

If a person has already had warts or papillomas once, then subsequently he will develop immunity to this type of virus. Therefore, in adults, juvenile warts, spinules and vulgar warts very rarely appear.
Therefore, it is SO IMPORTANT to maintain your immunity at a high level.

The main directions of prevention of human papillomavirus infection

Only one sexual partner
Using a condom during sexual intercourse
Personal hygiene measures in public places
A healthy lifestyle that maintains a high level of immunity
Correct work and rest schedule
Moderate physical training
Taking vitamins, fruits, juices
Vaccination against types 6, 11, 16, 18 - prevents the development of symptoms such as genital warts, neoplasia (dysplasia, or erosion) and cervical cancer, laryngeal papillomatosis. But the effect of the vaccine has not yet been fully studied. It began to be staged only 8 years ago. In addition, it does not form immunity to all highly oncogenic types of papillomaviruses.

Human papillomavirus (or HPV) is a family of viruses that cause warts, papillomas, dysplasia, or cancer of the cervix and genitals in humans. This is the most common viral infection of the genital area.

General family: Papillomaviridae. Latin name: Human Papillomavirus.
Abbreviation: HPV (as written in tests).

For doctors and students: the entire history of changes in the classifications of papillomaviruses on the website of the International Committee on Taxonomy of Viruses - link.

What is this virus?

1. Over 50 years, more than 100 types of human papillomavirus have been discovered. Pathogenic for humans - 80 types.
2. According to WHO, 70% of the world's population is infected with HPV by the age of 50.
3. In children, papilloma viruses cause warts.
4. In women, HPV types 16 and 18 are more likely than other types to lead to cervical cancer. Every year, 500,000 new cases of cervical cancer are diagnosed worldwide.
5. HPV is the overwhelming cause of genital cancer in women and men.
6. It is not possible to cure HPV completely and forever. You can only temporarily suppress its development and prevent formations from appearing.
7. The most effective prevention against cancer of the cervix and genital organs worldwide is the vaccine against types 6, 11, 16 and 18 of papillomaviruses.

This is what HPV looks like under an electron microscope

How does infection occur?

The source of the virus is the skin cells of a sick person. Not blood! Not saliva! Only skin or mucous cells.

If a patient has a papilloma, even a small one, it is the direct source of the virus!
However, upon examination, the patient may not yet have a wart or condyloma. The changes may still be microscopic and not visible to the eye (subclinical stage of the disease). But such a person can already transmit the virus to another person.

Infection usually occurs in childhood. Through microdamage to the child's skin (scratches, abrasions), the papillomavirus penetrates the skin and causes the appearance of warts. We read about what types of warts there are here: link.

In adults, certain types of virus (discussed below) cause the development of anogenital warts, or genital warts, on the genitals (). The transmission mechanism of these types is predominantly sexual.
But contact-household transmission is also theoretically possible - through general hygiene items, the toilet rim, taking a bath, visiting a bathhouse, swimming pool, etc.

Through microtraumas of the genital organs, the virus is transmitted from one sexual partner to another. In this case, the patient may also not have any changes visible to the eye. But there may be microscopic changes in the mucous membrane of the genital organs. And these altered cells are the sources of the virus.

Next, the virus penetrates the skin or mucous membrane and is met by various cells of the human immune system. In most cases, immune cells destroy the virus. Read more about the work of the immune system.

But if the immune system is weakened, the virus manages to penetrate the cells of the basal layer of the epithelium of the skin or mucous membranes, HPV DNA is integrated into the chromosomes of the cells and changes the functioning of these cells. The cells begin to divide excessively and grow in a limited area, externally turning into warts and papillomas.

The incubation period can be short - 3 months, or it can last for years. That is, the virus is in the body, it can be present in just a few epithelial cells. But the immunity is strong enough to prevent it from developing into a full-fledged formation visible to the eye.

This is how the papilloma virus develops in the skin

Remember

The types of HPV that cause warts enter the body during childhood.

The types of HPV that cause genital warts enter the body primarily through sexual contact.

In rare cases, the development of human papillomavirus infection in the human body can lead to malignancy (that is, degeneration into cancer). Therefore, all types of papillomaviruses are classified according to the degree of oncogenicity (that is, according to the degree of possible cancer development).

HPV types, oncogenic and non-oncogenic

(according to studies by McConcl D. J., 1991; Lorincz A. T., 1992; Bosch E X. et al., 2002; Kozlova V. I., Puchner A. F., 2003; Syrjanen S., 2003; Shakhova N. M. et al., 2006;).

1. Non-oncogenic HPV types, that is, those that never cause cancer: 1, 2, 3, 4, 5, 10, 28, 49
2. Low-oncogenic HPV types (very rarely cause cancer): 6, 11, 13, 32, 34, 40, 41, 42, 43, 44, 51, 72
3. Types of average oncogenic risk (average percentage of cancer degeneration): 26, 30, 35, 52, 53, 56, 58, 65
4. Highly oncogenic HPV types (high risk of cancer degeneration): 16, 18, 31, 33, 39, 45, 50, 59, 61, 62, 64, 68, 70, 73. This is especially important in women.

By the way, sometimes the classification changes. For example, HPV type 58 in women is no longer highly oncogenic. It began to be attributed to types with an average oncogenicity.

Occurrence in diseases

• In 73-90% of cases with cervical cancer, HPV types 16, 18 and 45 are found
• In 77-93% of cases with cervical cancer, the following are found: HPV types 16, 18, 45, 31 and 59
• In 80-94% of cases of cervical cancer, the following are found: HPV types 16, 18, 45, 31, 33 and 59
• Precancerous conditions in urology and gynecology are often combined with types 61, 62, 68, 70, 73 of HPV.

Most often found in analyzes

• human papillomavirus 16 (spelled HPV 16) - 50%
• human papillomavirus 18 (HPV 18) - 10%

HPV types 16 and 18

Symptoms and clinic

Symptoms and manifestations of HPV infection are warts, papillomas, dysplasia and cervical cancer. Different types of viruses lead to different manifestations in patients.

1. Warts

They are caused by the following types of HPV - 1, 2, 3, 4, 5, 10, 28, 49.

• juvenile (or flat) warts - caused by types 3 and 5 of the virus. These are small flat elevations on the skin that occur mainly in children. This type of wart is described in detail.
• spinules (or plantar warts) - caused by types 1 and 2 of the virus (you can read more about them).
• vulgar warts on the fingers - caused by type 2 viruses (detailed article about them).

2. Genital warts

Localization: on the genitals, in the anus, in the oral cavity and on the lips (types - 6, 11, 13, 16, 18, 31, 35). Read more about these warts -.

The main mechanism of transmission of this disease in adults is sexual. Very rarely, a contact route of transmission can occur - through shared toilet items, through a dirty toilet rim, using a shared bathroom, in a bathhouse, etc.

If a child is born to a mother with genital warts, the child is also infected and may subsequently also develop genital warts or papillomatosis of the larynx and respiratory tract (discussed above). However, the frequency of such symptoms in infants is extremely low. Children have a fairly high level of immunity, which protects them from such manifestations of infection.

3. Laryngeal papillomatosis

Small, flat wart plaques (somewhat similar to flat warts) appear around the genitals. It develops more often in men who constantly change sexual partners. Called by types – 16, 18, 31, 33, 42, 48, 51, 54.

5. Dysplasia and cervical cancer

More serious clinical manifestations of HPV infection in women are cervical intraepithelial neoplasia (CIN, or dysplasia) of the cervix and cervical cancer (see photo). This is the most common type of malignant course of this infection. More detailed article about CIN and dysplasia -.

In the photo - cervical cancer

Remember

Cervical erosion and HPV are FAR from the same thing. A detailed article about what cervical erosion is and how it differs from dysplasia and HPV -.

Modern medicine declares with 100% certainty that cervical cancer is caused exclusively by papillomavirus types 16, 18, 31, 33, 35, 39, 40, 42, 43, 55, 57, 59, 61, 62, 66, 67.

The diagram shows the development of HPV infection over the years

6. Skin cancer of the penis (Bowen's disease)

Caused by virus types 16 and 18.

Today, some foreign scientists believe that the human papillomavirus is the cause of cancer of any location. Since cancer is a malignant tumor of the epithelium of the skin or mucous membrane, therefore, the HPV virus, which causes dysplastic phenomena in the epithelium, causes the appearance of cancer. And with cervical cancer this has been proven 100%.

There is evidence for breast cancer and laryngeal cancer, although it has not yet been formalized into global recommendations. And, according to some cancer researchers, the day is not far off when cancer of other locations (for example, intestines) is also recognized as the result of the activity of the human papillomavirus in the human body.

Remember

Any viral infection that is constantly present in the human body (and HPV is one of these) is activated only when immunity decreases.

Diagnostics

1. PCR analysis

The main method for diagnosing papillomavirus is the PCR reaction. Using special reagents, the presence of HPV DNA in material from a patient is determined. The most common types of analysis for HPV are virus types 16, 18, as well as a number of other highly oncogenic types.

Material for analysis is taken from the mucous membrane of the woman’s vagina and cervix. In men - from the mucous membrane of the penis.

Below in the photo is an example of a PCR analysis and its decoding.

PCR can detect the presence of a virus even in a latent (that is, sleeping) state. Therefore, it is important to determine the viral load, or concentration of the virus.

The PCR reaction can also give a false result, both a false positive and a false negative result, especially if the conditions for its implementation are violated (even a push of the table on which the study is being carried out can lead to such a false result).

Thus, according to modern researchers in the West, up to 20% of all PCR results for papillomavirus were false. And this fact did not depend on the complexity of the equipment and the quality of the reagents.

2. Digene test

New research gaining popularity in the medical community. This test is used to determine the presence of clinically significant concentrations of the virus. Thanks to this test, it is possible to identify whether the viruses in the patient’s body have a high or low degree of oncogenicity.

The Digene test is used in conjunction with a cytological examination of the cervix, and they are also evaluated comprehensively.

3. Examination by a gynecologist and/or urologist

4. Pap test

Other names are cytological examination, or "Pap smear."

A smear taken during a gynecological examination is examined. This study is often called "liquid-based cytology", or simply "cytology".

In this case, a laboratory doctor, under a microscope, determines the presence or absence of pathologically altered cells, which should not normally be present, but they appear only with the development of the disease. The presence of such altered cells may indicate the presence of CIN (or cervical dysplasia) in a woman.

5. Histological examination

A microscopic piece of tissue is examined, also taken during a gynecological or urological examination. Another name for this study is "biopsy". Under a microscope, the doctor evaluates the degree of change in the tissue taken for examination.

How to decipher the analysis for HPV?

Example of PCR analysis for HPV

Interpretation of the analysis

The unit of measurement is the number of genome equivalents (in simple terms, the number of viruses) per 100,000 human epithelial cells (that is, by 10 to the 5th power).

Abbreviated as: Lg

Gradations:

1. 3 – 5 Lg. This is a clinically significant indicator. The risk of developing the disease is average. You need to be examined by a doctor.
2. > 5 Lg. High viral load. You should definitely undergo a full examination to exclude cervical dysplasia.

What is a reference value

This means the average statistical indicators for this study for this age group. That is, in a simple way, the reference values ​​​​are the norm.

For HPV reference values ​​are negative. That is, normally HPV DNA should not be in the analyzes.

What is KVM?

KVM is the control of material taking. Normally, the doctor should take a scraping so that the sample of material contains at least 10,000 (or 10 to the power of 4, or 4Lg) epithelial cells.
If the CME value is less than 4Lg, this means there are few cells for analysis. The analysis is not recommended, as it will be uninformative, and the doctor is recommended to repeat the collection of material.

Treatment

Remember

• In the treatment of human papillomavirus, you need to know: the virus may not be completely removed from the body. The main goal of treatment is to remove manifestations of the virus and reduce its concentration in the body so that the human immune system itself suppresses the virus.
• First, the doctor must make the correct diagnosis, and this is already half the treatment!!!
• Self-medication has low effectiveness and can lead to progression of the process. Self-medication for diseases of the genital area is especially dangerous.
• With all types of treatment, a healthy lifestyle that increases immunity is required.

3 areas of treatment are required

• removal of manifestations - warts, condylomas, dysplasia (erosion) or cervical cancer
• taking antiviral drugs (rarely used in the treatment of warts)
• strengthening the immune system (rarely used in the treatment of warts)

1) Removal

Laser removal of papillomas

Radio wave removal of papilloma

The radio wave evaporates the formation in the same way as a laser. .

Removing papilloma with a scalpel

Removal of papillomas with an electric knife

In fact, this is the same scalpel, only electric. Currently, it is practically not used in cosmetology.

Liquid nitrogen removal

A detailed article about this method -

Cauterizing agents

Pharmacy local necrotizing drugs (acids, alkalis) are used:
- Super clean
- Solcoderm ()
- Duofilm ()
- Collomak()
- Verrucacid, or feresol ()
- Condilin ()
- and a number of others.

2) Antivirals

• Isoprinosine (or groprinosin): 2 tablets - 3 times a day; 14-28 days (more detailed article about this drug -).
• Allokin-alpha: 1 ampoule, powder dissolved in 1 ml of 0.9% sodium chloride, administered subcutaneously once every two days, course - 6 injections (described in more detail about Allokin).
• Epigen intimate spray: spray the affected area 4 times a day throughout the entire treatment period (more detailed instructions).
• Panavir: available in different forms - gel, spray, suppositories, injection solution - it all depends on the prevalence and localization of the process (detailed material about Panavir).

3) Drugs that increase immunity

Polyoxidonium, Roncoleukin, Immunal and others:

• Immunal: 1 tablet - 4 times a day, the course is from 2 to 8 weeks.
• Reaferon: powder 1 bottle (1 million units), diluted with water (half a teaspoon), drink 30 minutes before meals - 2 times a day, for 10 days.
• Polyoxidonium: 1 suppository (12 mg) inside the vagina or rectum at night, every other day - 10 times.

HPV and pregnancy

Attention

The human papillomavirus does not affect reproductive function, that is, the virus does not prevent a woman from having a child.

If papillomavirus infection is detected during pregnancy:

• the first is to find a good gynecologist and be observed by him until the birth,
• the most important thing is what manifestations of the infection a woman has, the tactics of the doctor will depend on this,
• The virus has no effect on the fetus!
• warts and papillomas can be removed after childbirth,
• minimum drugs (only as needed) during pregnancy,
• during childbirth, the child can become infected, passing through the birth canal,
• in the presence of expressed changes in the pregnant woman’s cervix may require a caesarean section,
• in the absence of manifestations - natural birth.

In general, cesarean section for HPV infection is rarely performed. And manifestations of infection in children subsequently are also extremely rare or insignificant.

Prevention

Prevention is the best cure. Remember this phrase, especially when it comes to the sexual sphere.

Nature has come up with a wonderful mechanism for healing and prevention for a person, which then helps him not to get sick again. This is the immune system.

If a person has already had warts or papillomas once, then subsequently he will develop immunity to this type of virus. Therefore, in adults, juvenile warts, spinules and vulgar warts very rarely appear.

It is on this principle that the method of vaccinating a person against various infectious diseases, including papillomavirus, is built.

This is why it is SO IMPORTANT to maintain your immunity at a high level. Read a detailed article about how to strengthen your immune system.

Specific prevention of PVI infection

• Vaccine "Gardasil" made in the USA. This vaccination against types 6, 11, 16, 18 prevents the development of symptoms of infection such as genital warts, neoplasia (dysplasia, or erosion) and cervical cancer, cancer of the skin of the penis in men. In many developed countries, HPV vaccination is carried out very actively, starting from 11-12 years of age (link), until the time of sexual activity, when infection already occurs. It is given to both girls and boys.
• Vaccine "Gardasil 9". This vaccine is nine-valent, that is, it acts against 9 types of virus: 6, 11, 16, 18, 31, 33, 45, 52 and 58. The effectiveness of preventing cervical cancer is from 98% to 100%.
• Vaccine "Cervarix". This vaccine forms immunity against 2 types of virus: 16 and 18.

Nonspecific prevention

• Personal hygiene measures in public places
• A healthy lifestyle that maintains a high level of immunity
• Correct work and rest schedule
• Moderate physical training
• Taking vitamins, fruits, juices
• Only one sexual partner (ideally)
• Using a condom during sexual intercourse

And in conclusion - several videos on the topic of the material, recommended for viewing.

Attention: If the doctor did not answer your question, then the answer is already on the pages of the site. Use the search on the site.

Human papillomavirus is one of the most common infectious diseases that occur in humans. In terms of the number of people affected, it is second only to cold viruses.

The virus enters the skin and mucous membranes through damage, even the smallest, especially on the hands, but does not enter the blood. Warts or papillomas are the only symptom of this disease.

There are about 120 varieties of the virus, all of them manifest themselves differently: the location on the body and the appearance of the formations differ.

For example, plantar warts, which occur only on the foot and toes, are caused by only five types of HPV: 1, 2, 4, 27 and 57.

Anogenital warts or genital warts are caused only by virus types 6, 11, 13, 16 and 18. The surface of these formations is similar to a head of cauliflower.

Such a wart cannot be found on the hands or feet, since they are not found anywhere else except the anus and genitals.

In 1999, the human papillomavirus shook the whole world. A certain Dr. Wolbumers studied about a thousand women with cervical cancer and found that almost all of them (99.8%) were infected with HPV.

A little later, a connection was discovered between other types of cancer and papillomatosis.

The planet was gripped by mass psychosis - people, having learned about their HPV infection, already considered themselves terminally ill.

Subsequent studies in this area found that the percentage of people with cancer and HPV in the same vial was slightly lower than according to Wolbumers.

It also turned out that of the almost 130 types of the virus, not all are cancer-hazardous. Moreover, the types of virus that are associated with oncology have different strains, of which only a small part is capable of causing malignant processes.

When a terrible diagnosis looms on the horizon, and the doctor operates in terms of “the second most common type of cancer in women,” you involuntarily want to give away your last money just to increase your chances of survival.

At the same time, doctors do not always tell that treatment with antiviral and immunomodulatory drugs, cauterization and surgical removal of warts does not guarantee a cure and can lead to the opposite consequences.

The best way to overcome fear and choose the necessary treatment is to understand what viral warts are.

“Adult” and “children’s” warts

So, warts are contagious, they are transmitted from a person who has them to a healthy person through lesions on the hands, feet, fingers and other areas of the skin and mucous membranes.

Viral warts occur only in children and adults. In older people, growths caused by HPV do not occur, and senile papillomas have nothing to do with viruses.

“Adult” warts are transmitted primarily through sexual contact and appear in the genital area.

They never appear on the hands or fingers. 70% of sexually active young people, especially those who do not seek a regular sexual partner, are repeatedly infected with HPV during their lifetime.

However, only four women in every 100 thousand get cervical cancer.

This does not mean that you should not pay attention to HPV of cancer-dangerous types, but there is also no reason to consider yourself a cancer patient within five minutes.

Any risk factors, especially if there are several of them, are a reason to be additionally observed by a doctor and monitor your health more carefully.

Most warts are completely harmless. These are “childish” formations that dot the arms, legs, and are found on the foot, face and toes. The reasons why they are more common in children are simple.

Firstly, children are larger, closer and more often in contact with each other. Secondly, children have not yet developed hygiene skills; they touch their faces more often, bite their nails and sweat.

Touching is an important way to explore the world, so it is on the hands that children most often develop warts, and from there they spread further throughout the body.

The papilloma virus is quite viable and feels good outside the host’s body for several months.

At this time, a child can become infected by touching a door handle, a towel that an infected child used to dry himself in kindergarten, or a handrail on a playground or play center.

Walking barefoot in public places, a child can pick up a wart on the foot or toe. All this makes children vulnerable to HPV and the warts it causes.

Sometimes it is the parents themselves who put their children in danger. For example, when a child is wrapped up too much, which makes him sweat more. It has been noticed that growths appear more often on constantly moist areas of the skin.

In addition, excess heat suppresses the body's defense mechanisms, making it vulnerable to a wide variety of viruses, including HPV.

The human immune system is capable of successfully defeating most viruses, and HPV is no exception.

The only difference between immune protection against influenza and against HPV is that the body needs more time. Within a few months, to a maximum of two years, warts in children disappear without a trace, even if no treatment was carried out.

To treat or not to treat – that is the question

In most cases, treatment of warts, especially in children, is not required. Growths on the foot, finger or toe, on the face and other parts of the body go away on their own as soon as the body copes with the virus.

However, in some cases, treatment is necessary:

• if warts grow rapidly, forming entire groups, then this is evidence that the immune system is not coping and needs help;
• if a harmless formation on the finger, toe or face is constantly damaged, especially in children;
• if the wart causes pain, such as a plantar callus on the foot or toe;
• if the papilloma looks unaesthetic and repulsive, causing moral suffering.

In all these cases, the removal of the wart in children and adults is advisable.

If there are no aggravating circumstances, then treatment can be carried out at home, but before that it is important to get a doctor's confirmation that the formation on the skin is benign.

Removing papillomas on the hands is the simplest thing. Firstly, because the skin on the hands is not as delicate as on the face, and it is not so easy to damage.

Secondly, even if the treatment leaves scars, they will not be as noticeable on the hands as on the face.

Third, treating foot or toe warts can be painful and limit your ability to move even more than the plantar callus itself.

When choosing a method, you should evaluate various factors. If it is necessary to remove a wart on the face, then you cannot use such powerful drugs as Supercelandine, due to the risk of scarring the skin.

All over the world, wart removal is performed with acid-based preparations, for example, salicylic acid. Treatment lasts for a month until the wart disappears.

The skin on the finger or foot must be soaked in warm water for 15 to 20 minutes, wipe thoroughly and carefully apply ointment, patch or alcoholic acid solution to the wart. The procedure should be repeated daily, removing dead skin before each procedure.

In a similar way, warts are removed using celandine, but its juice is active only during the flowering period of the plant (from May to July, depending on the region).

Some people have success using garlic for this purpose by applying it to the wart twice a day.

If removing warts using improvised means is not successful, and the warts continue to bother you or change their appearance (color, shape, size, bleeding ulcers appear on them), you should not look for additional reasons to consult a doctor.

Depending on the location of the growth and other additional conditions, an experienced dermatologist will choose a way to remove the body of the wart without damaging your body.

For facial skin, exposure to radio waves or laser resurfacing is best; on less delicate areas of the body, official medicine uses chemical cauterization, freezing with liquid nitrogen, and even a scalpel.

The latter, however, is used less and less, and then only as the cheapest method.

Human papillomavirus type 56 in women and men

• 1 Features of type 56 virus
• 2 Modes of transmission and risk factors
• 3 Risks for men and women
• 4 Symptoms of HPV
  • 4.1 What is dangerous during pregnancy?
• 5 Diagnostics
• 6 Treatment of infection
• 7 Prevention methods

More than 60% of people on the planet are infected with the human papillomavirus. HPV 56 belongs to this family. The group of viruses is similar in symptoms and ways of infection, and differs only in oncogenic risk and cross-infection. The diagnosis of HPV of this type is terrible for most people, and this is justified, as it provokes the development of neoplasia (cancer) in the cells of the reproductive organs, reduces life and its quality.

HPV type 56 is more often sexually transmitted and poses a significant threat to the human reproductive system.

Features of type 56 virus

Human papillomavirus (Human papillomavirus) is a heterogeneous group of viruses that affects the skin and mucous membranes, such as the cervix, anal canal, oral cavity. More than 600 types (strains) are known. HPV is the most common infection that is transmitted during sexual contact. It is so disseminated that all sexually active people can be its carriers at any time in their lives. All strains can be divided into 3 groups:

• HPV with low oncogenic risk (HPV 3, 6, 11, 13, 32, 34, 40, 41, 42, 43, 44, 51, 61, 72, 73);
• HPV with average oncogenic risk (HPV 30, 35, 45, 52, 53, 56, 58);
• HPV with high oncogenic risk (HPV 16, 18, 31, 33, 39, 50, 59, 64, 68, 70);

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Transmission routes and risk factors

HPV is spread in 33% of cases through sexual transmission - the main route. Since during sexual intercourse the integrity of the epithelium is violated, which allows the human papillomavirus type 56 to penetrate and cause infection. There are also other ways of transmitting the virus:

• baby in labor;
• through touch - by contact (in public places through minor wounds, scratches on the skin).

The human papillomavirus is not transmitted aerogenously, that is, through the air and touching objects, for example, a door handle, a handshake.

People with weakened immune systems, uncontrolled sex life and poor hygiene are at risk of contracting HPV type 56.

Human papillomavirus exists in the body in a latent state. In 90% of cases, within 6-12 months the body copes with the infection on its own - self-healing. The onset of symptoms and transition to a chronic disease, with frequent exacerbations, occurs if the following risk factors are present:

• reduced immunity or immunosuppression;
• overwork, chronic stress;
• a large number of sexual partners;
• early onset of sexual activity;
• HIV infection;
• presence of other STDs;
• nutritional deficiency;
• drug use, smoking, psychoactive substances;
• genetic predisposition;
• pregnancy.

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Risks for men and women

Type 56 belongs to the oncogenic risk group, affecting the human reproductive system, causing genital infection in women and men. Both sexes, regardless of sexual orientation, will be infected with at least one type of HPV virus during their lifetime. For men, HPV is not dangerous because it is not associated with health risks. Genital warts occur in men infected with the virus, but are extremely rare. In women, on the contrary, the frequency of occurrence is quite high - 80%. Also, type 56 virus in women leads to erosion and cervical dysplasia - pathological changes in the normal epithelium of the internal organ. The DNA of the virus, weakening the human immune system, activates the appearance of bacterial, fungal, and other viral infections.

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HPV symptoms

After an incubation period, which lasts on average from 15 days to several years, symptoms of infection appear in only 10% of cases. It is generally accepted that there are no symptoms of the disease. Despite the fact that the virus causes changes in skin cells and mucous membranes, they are insignificant and do not cause concern or complaints in the patient. Papillomavirus 56 causes noticeable changes in the presence of risk factors. Warts or genital warts, which can be found around the anus, on the penis, and scrotum in men. The same condylomas appear on the female genitals - on the labia majora and minora, on the clitoris, and also in the urethra. Their appearance may be accompanied by itching and burning.

HPV type 56 provokes the growth of intimate warts, and they are a source of physical discomfort.

Condylomas are formations that protrude above the surface of the skin or mucous membrane on a stalk. They have a variety of colors - from pale pink to dark brown. They tend to merge and grow rapidly. They are characterized by growth not only above the surface of the skin, but also grow inside, which makes it difficult to remove.

The US Center for Infectious Disease Control states that HPV infection causes cancer of the cervix and vagina in women and penile cancer in men. HPV type 56 also causes cancer of the anal canal and oropharynx. But dysplasia, and then cervical cancer, is still of particular importance.

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What are the dangers during pregnancy?

During pregnancy, a woman's immunity decreases due to hormonal imbalance, which leads to the expectant mother's sensitivity to infections, especially HPV. A history of HPV does not affect a woman's fertility, but tell your doctor if you have an obvious infection during pregnancy. Pathological growths on the genitals cause certain problems during pregnancy.

1. Due to an imbalance of hormones, warts in the urethra can increase in size and grow, making it difficult to urinate.
2. In the vagina, warts reduce the elasticity of its wall and can also cause blockage of the lumen during childbirth. If the condylomas are not removed, a caesarean section will be required to deliver the baby. Infants whose mothers have the papilloma virus may develop warts in the throats - laryngeal papillomatosis. What causes wheezing and asphyxia (difficulty breathing) in children.

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Diagnostics

Diagnosis of HPV type 56 involves laboratory testing of biomaterial.

Diagnosis of the human papillomavirus begins with an external examination of the skin and mucous membranes to identify atypical neoplasms. In women, during mandatory preventive examinations at the gynecologist, a Pap smear is done during a colposcopic examination. In fact, 25% of atypical smears will detect the virus. Papillomavirus testing is a screening test for women 25 to 65 years of age. There is no reliable test for detecting HPV infection in men. But a group of people at high risk of developing anal cancer may be offered an anal swab test.

The PCR method - polymerase chain reaction - is not ineffective. It detects the presence of viral DNA in epithelial cells with 95% accuracy, thus it is possible to differentiate between different types of HPV. In association with HPV type 56, there is also HPV 51. There is another screening test - the Digene test, with which a high concentration of papillomavirus is determined.

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Treatment of infection

After confirmation by diagnostic procedures of HPV type 56, therapy should be started, which is aimed only at the consequences of the virus. After all, there is no specific treatment that would eliminate the virus from the body. Treatment is divided into two groups:

• surgical;
• medicinal.

Surgical tactics are aimed at removing atypical tissues: the formation of genital warts, warts and other neoplasms in tissues and mucous membranes. If warts or other neoplasms are found, then known removal methods are used:

• cryosurgery;
• laser therapy;
• chemodestruction with trichloroacetic acid;
• radio wave surgery;
• electrocoagulation;
• radical methods - amputation of the cervix.

Treatment of HPV type 56 is carried out with medication and surgery.

Using such surgical methods, the focus of the affected tissue is removed. Efficiency ranges from 65 to 45%. But, due to the fact that it is impossible to control the complete removal of the affected tissues, the recurrence rate is about 50% of cases. If after 3 treatments there is no noticeable improvement or if after 6 treatments the warts have not disappeared completely, another type of therapy is used.

It is better to treat HPV using a combination of medications and surgical techniques, then the effectiveness is up to 90%. Drug treatment includes the use of antiviral drugs ("Interferon"), and in the subsequent period, immunomodulators that will increase the resistance of the immune system to infections ("Likopid", "Immunomax" and others).

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Prevention methods

The main method of preventing STDs and the papillomavirus group is the use of protection during sexual intercourse. Another method of creating immunity against HPV is vaccination. Doctors recommend that children at 11 or 12 years old get vaccinated. Men under 21 and women under 26 can be vaccinated if they did not get vaccinated when they were younger. HPV vaccines are isolated from proteins called virus-like particles (VLPs) produced using recombinant technologies. They do not contain any live biological products or viral DNA, so they are safe and create a robust immune response. The HPV vaccine also has side effects, but they are quite minor. In addition, its effectiveness is much higher than the side effects. Side effects:

• pain;
• swelling at the injection site;
• redness;
• increased body temperature;
• headache;
• increased feeling of fatigue;
• tingling sensation in the muscles;

Vaccination is recommended for gay people and people with weakened immune systems (HIV-infected people, patients taking glucocorticosteroids). If infection and the manifestation of the above symptoms are detected, there are risk factors, then it is necessary to contact such specialists as a gynecologist, urologist, or dermatovenerologist. The effectiveness of immunotherapy and their recovery depend on the consciousness of patients.

Methods for diagnosis, prevention and treatment of high oncogenic risk HPV

In recent years, experts have paid special attention to research into the group of HPV with high oncogenic risk. The main danger of these human papillomaviruses is that they can cause the development of cancer. Many people call the creation of a special quadrivalent vaccine against cervical cancer one of the greatest achievements of medical science in this area. Proponents of the new method argue that such a “cancer vaccination” for young women who are just planning to begin sexual activity is the most effective way today to protect against papillomas and further cancer problems in the cervical area.

Papillomaviruses (HPV) are the second most common viruses in humans. An analysis of the data available to the World Health Organization shows that almost 70% of the entire population of our planet is infected with HPV. The existence of more than 100 HPV DNA types has been established, which experts distinguish by numbers. Almost 60% of all existing genotypes do not pose a threat to human health. The rest, to a greater or lesser extent, can provoke the appearance and development of diseases of the mucous membrane, skin, ENT organs, and reproductive system.

Routes of transmission of the papilloma virus

The only sources of the virus, including high-risk HPV, from which infection is possible, are the cells of the affected skin or mucous membrane of a sick person. The virus cannot be transmitted through blood and saliva.

The threat of infection is not all of the patient’s skin, but only areas of local damage - warts, papillomas, etc. It should be noted that at the subclinical stage of the disease, changes in the skin are already present, but are small and imperceptible. Therefore it is extremely important:

• follow basic rules of personal hygiene,
• have a regular sexual partner,
• support the body's own immune forces.

In most cases, the virus enters the body in childhood through damaged skin when receiving scratches, abrasions. As a result, children develop warts.

After reaching adulthood, the main way to get HPV becomes sexual. Damage by the virus to the mucous membrane, skin causes opposition from the cells of the immune system. If the human body’s defense mechanism is strong enough, the virus will soon be destroyed. A weakened immune system does not have enough strength to provide the necessary resistance. In this case, HPV manages to infect the basal layer of the skin and mucous membrane. There, the DNA of the virus is integrated into the structure of the DNA of cells, changing them, stimulating abnormal growth, which is manifested by the appearance of papillomas and warts on the surface.

Dangerous types of human papillomavirus

The development of certain types of human papillomavirus infection can lead to the degeneration (malignization) of benign formations into malignant, cancerous ones. The classification of viruses is based on the assessment of these properties:

• not causing oncological changes in cells and tissues (1, 2, 3, 4, 5, 10, 28, 49);
• with a low risk of cancer (6, 11, 13, 32, 34, 40, 41, 42, 43, 44, 51, 72);
• with an average percentage of malignant transformation (26, 30, 35, 52, 53, 56, 58, 65);
• highly oncogenic HPV types (16, 18, 31, 33, 39, 45, 50, 59, 61, 62, 64, 68, 70, 73).

Changes may occur in this classification over time. Thus, virus number 58 was transferred from the group of HPV of a high oncogenic type to the group of medium risk of developing cancer.

The onset of abnormal cell development with activation of the virus introduced into them can be provoked by:

• failure of the hormonal balance of the female or male body;
• weakening of the immune mechanism;
• the presence of chronic, indolent diseases;
• frequent stress.

The most dangerous types of HPV for women and men

HPV types with a high oncogenic risk pose the greatest danger when entering the human body. To a greater extent, this threat concerns female representatives. It was established that in women diagnosed with cervical cancer, during examination, human papillomaviruses of high oncogenic risk or at least one variety from the list of numbers were identified: 16, 18, 31, 45, 33, 35, 39, 52, 58 59. Various urological (in men) and gynecological (in women) precancerous conditions were accompanied by the presence of 61, 70, 73, 62, 68 types of human papillomavirus of high oncogenic risk.

It should be noted that most often the analysis detects infection with HPV types 16 and 18. They are detected in almost 70% of cases of infection. Human papillomavirus of high carcinogenic risk can cause the development of:

• adenocarcinomas;
• cervical cancer;
• anal cancer;
• vaginal cancer;
• vulvar cancer;
• penile cancer;
• cancer of the larynx and oral cavity.

HPV in the female body

The physiological features of the structure of the female genital organs determine the fact that HPV with a high carcinogenic risk is easier to penetrate into the body. Microtraumas and microcracks that appear on the surface of the mucous membrane during sexual intercourse are practically invisible and imperceptible. But they are the “gateways” for easy penetration of the papillomavirus. As a result of research and observation, it has been established that a condom is not 100% protection for the penetration of HPV. Such infection makes a woman at high risk of developing cancer of the genital area, increasing the risk by 300 times.

Attention! If the result of the examination is a positive result for the presence of an oncogenic type of HPV, this does not mean that the woman is already sick or will definitely have cancer. Once you are in a risk group, you need to systematically monitor (by taking appropriate tests) the activity of the virus in the body.

If the need for examinations is ignored and the patient is in satisfactory health, the development of the disease can be detected already at the stage of invasive (spread to other organs) cancer.

Women who do not have a regular sexual partner, women over 40 years of age, and patients with low social status are most at risk. The list can be supplemented by pregnant women, since this period in women is characterized by the progress of hormonal changes in the body, which lowers immunity, which can cause the activation of a latent (“sleeping”) virus.

HPV in the male body

The methods of infection for men are similar to those for women, but the behavior of the papilloma virus differs in the nature of the development of the infection. Due to the anatomical features of the male urogenital zone, after exposure to a highly carcinogenic virus, in the vast majority of cases (provided that a satisfactory immune system is present), the disease goes away on its own in 80% of cases. Sometimes, infected men are carriers of an oncogenic type of papillomavirus, without even knowing it.

Thus, a man can infect his partner without having clinical signs of the disease. At the same time, the risk of developing an oncological process remains low. A situation is possible when close, related people undergo an examination that detects a certain HPV genotype in only one of the partners. This result is not evidence of adultery, but only a consequence of the biological characteristics of the vital activity of the virus. For example, in a man, immunity quickly suppressed and destroyed this HCR HPV, while re-infection with this genotype can no longer occur.

Symptoms of the presence of dangerous HPV in the body

Most cases of infection in women and men occur without clinical signs. A greater number of patients who have observed symptoms characteristic of the disease are women. The most common manifestations of infection by the human papillomavirus are:

• Detection of papillomas and condylomas on mucous membranes and skin.
• The appearance of unusual vaginal discharge and bleeding.
• Painful sensations in the lower abdomen and vagina that appear during and after sexual intercourse.
• General weakness, malaise.
• During an examination by a gynecologist, detection of changes in the condition and structure of the tissues of the cervix, the presence of an inflammatory process.

Papillomas that appear on the skin, as a rule, are not classified as oncogenic types of formations. They do not need to be removed.

When exposed to provoking factors, such as frequent injury, severe weakening of the immune system, degeneration of benign tissue occurs. A malignant papilloma is formed. You should be wary of:

• dark color education,
• uneven, inflamed edges;
• the appearance of hard crusts on the surface;
• fast growth.

Malignant papillomas must be removed immediately.

Condylomas appear on the surface of the external genitalia, on the mucous membrane after the human papillomavirus of high carcinogenic risk has been transmitted sexually (in rare cases, through household contact). This type of formation has an increased risk of injury and cancerous degeneration. Therefore, like malignant papilloma, it needs to be removed surgically.

Diagnosis of HPV

It is possible to detect the presence of HPV in the body of a man or woman, accurately determine its genotype, as well as the level of existing oncogenic risk, using two main research methods:

1. PCR. This is a “polymerase chain reaction”, which is a highly accurate diagnostic method involving the study of genetic material. A smear from the skin or mucous membrane is analyzed. The use of special enzymes in laboratory conditions makes it possible to repeatedly copy (type) elements of RNA and DNA of infectious disease pathogens that are found in the biomaterial under study. The results are then compared with a database to determine the pathogen. This study reveals the HPV genotype, but does not show how much of this infection is contained in the body.
2. The Digene HPV test is a skinning test that should detect precancerous changes on the cervix. The analysis does not require special preparation and has no contraindications. The gynecologist takes a scraping from the cervix; the test result can be ready within 24 hours. The Digen test is recommended for patients with clinical signs of the presence of human papillomavirus; it is able to identify the virus, establish its type, and determine the viral load (the amount of virus in the body).

To get tested for the detection and establishment of HPV, you need to contact any specialized laboratory. But a better decision would be a preliminary visit to a gynecologist, who, after a survey and examination, will give professional recommendations on the most effective research method, as well as a referral for tests. Having received their results, the specialist will choose a treatment tactic that is adequate to the patient’s condition.

In addition, if a high-risk papillomavirus is suspected, the doctor will send a smear taken during a gynecological examination of the patient for cytological examination. Studying cells under a microscope will reveal the presence of pathological changes in the cells and establish cervical dysplasia.

Treatment of HPV at high risk of cancer changes

Detection of an oncogenic type of HPV during examination is not a death sentence. If the patient has no clinical signs of the disease, then no treatment is needed. You should regularly undergo preventive examination by a specialist and take tests.

If a high viral carcinogenic load is detected, the doctor will recommend individually selected comprehensive treatment, which will be aimed at:

• fight against the virus (antiviral agents);
• increasing human immunity (by taking special immunomodulatory drugs);
• removal of condylomas using one of the modern methods (cryodestruction, electrocoagulation, radio waves, laser).

Malignant diseases develop in patients for various reasons. One of the main unfavorable factors leading to cancer processes is HPV infection. The greatest danger comes from strains with a high carcinogenic risk.

HPV type 68: what is it?

This species is considered one of the most dangerous, as it is often found when diagnosing genital cancers in patients. You can become infected with HPV 68 through unprotected sex or using other people's objects.

The pathogen poses a threat to both men and women. HPV type 68 DNA quickly penetrates into the genetic material of cells and provokes the reproduction of atypical structures. When infected with strain 68, the following pathologies can develop:

• oncology of the phallus;
• cancer of the urinary organs;
• dysplasia or cancer of the cervical canal;
• malignant degeneration of vulvar tissue.

Features of HPV type 73

This strain of the pathogen is also considered oncogenic, but it rarely leads to the formation of malignant tumors. According to statistics, from the moment of infection with HPV 73 until the first signs of its vital activity appear, about 20 years can pass.

Clinically, this type of pathogen manifests itself in the form of flat papillomas located on the surface of the cervix. The formations do not differ in color from healthy epithelium, so even an experienced gynecologist can not easily notice them during an objective examination. If infection with HPV 73 genotype is suspected, a colposcopy is recommended.

Treatment of papillomavirus 68, 73

Therapeutic tactics involve an integrated approach. Destructive methods are prescribed in conjunction with drug treatment. The latter can be physical (electrocoagulation, cryodestruction, laser exposure, radiotherapy) or chemical - treatment of growths with concentrated substances.

Drug treatment of HPV 33 and 68, 73 strains involves the appointment of antiviral agents - Genferon, Acyclovir, Panavir. They are combined with immunostimulating drugs - Amiksin, Lavomax, Groprinosin. This complex allows you to inhibit the virus and prevent its replication.

Even after such treatment, there is a possibility of re-infection with the papillomavirus 68, 73, so preventive measures should be observed even after complete recovery. Only vaccination, which is recommended between the ages of 9 and 26, will help to avoid infection. For this purpose, the drugs Gardasil and Cervarix are used. Under their influence, antibodies to the pathogen are produced, which remain in the body forever, which makes it possible to avoid infection with papillomavirus.

To date, about 80 types of HPV DNA have been studied in detail., the total number of which reaches hundreds. Many types do not pose a serious danger, but some varieties of papillomavirus can provoke the development of oncological pathologies on the organs of the female genitourinary system.

There are about thirty such highly oncogenic types that every woman is at risk of encountering.

Determination methods

It is possible to establish what type of papillomavirus is present in a woman's body only through a complete diagnosis, but the varieties of the virus may differ in external manifestations. The types of highly oncogenic nature include the following types of HPV: 16, 18, 31, 33, 39, 45, 50, 59, 61, 62, 64, 68, 70, 73, 82, 83.

At the same time, the highest danger is attributed to HPV types 16 and 18, which most often become the causes of cervical cancer.

Attention! All highly oncogenic types are transmitted through sexual contact. Papillomatous formations can be found on the labia minora, in their inner part (vagina and cervix), as well as in the anus, where genital warts are most often localized.

Highly oncogenic types of HPV differ in external manifestations, which are represented by the development of papillomas and genital warts on the genitals, which can subsequently provoke serious lesions of the vulva, vagina, and cervix.

In other words, the listed varieties of the pathogen are manifested, first of all, by genital warts, upon detection of which, specialists must prescribe a comprehensive examination and treatment if necessary.

According to medical studies, no more than 5% of patients face severe changes in the cervix, represented by dysplasia of the second and third degrees, after 2-3 years from the moment of infection.

Such low rates are explained by the well-coordinated work of the immune system in most cases, which suppresses the activity of the pathogen. As for cervical cancer, this pathology is diagnosed in only 20% of women who have been diagnosed with grade 3 dysplasia.

What to do?

If highly oncogenic HPV is detected in the body, the disease cannot be treated independently., because rash actions can provoke the development of a precancerous condition. Treatment of external manifestations is aimed at removing them, taking antiviral drugs and immunomodulating agents.

Removal of papillomas, warts and condylomas on the genitals is performed by surgical methods and using special pharmacy products, among which the most effective are: Panavir, Viferon, Condylomas, Aldara.

Important! The destruction of growths must be supplemented with Isoprinosine or other analogues with antiviral and immunomodulatory effects.

Outpatient removal of papillomas and condylomas in the genital area is performed by:

It should be noted that in most cases, when highly oncogenic type papillomas are detected, specialists prefer the removal of formations by laser and radio wave method (Surgitron apparatus), because only this technique makes it possible to exclude recurrence and cancerous transformation.

The use of folk remedies in the destruction of such formations is not recommended.

Varieties of human papillomavirus with average rates of rebirth

Reference! The following types of HPV differ in the average rates of cancerous degeneration: 26, 30, 35, 51, 52, 56, 58.65.

Despite the lower danger of these varieties of papillomavirus, it is still not recommended to leave its manifestations without due attention.

Their signs

According to external manifestations, the listed types of HPV with an average oncogenic risk can be divided into the following categories:

1. HPV 26– common warts;
2. HPV 30– recurrent papillomatosis of the respiratory organs;
3. HPV 35, 51, 52, 56 can provoke carcinoma localized on the cervix, vulva or vagina, as well as squamous intraepithelial lesions.

Often, the result of infection with HPV types with an average oncogenic risk is the development of several other complications not related to oncology. So, against the background of the presence of HPV 51 in the body, the development of bowenoid papulosis may begin, which looks like small warts in the genital area.

Features of treatment

As in the case of any papillomatous growths, the treatment of HPV manifestations with an average oncogenic risk involves a combination of destruction of papillomas and warts with strengthening the immune system and providing an antiviral effect from the inside.

In order to destroy papillomatous growths, you should use Supercleaner, Verrukacid, Viferon, Panavir, Solcoderm, Ferezol and other pharmacy analogues.

At home, it will be possible to get rid of papillomas with the help of freshly squeezed celandine juice, which can be used as an independent medicine or in combination with other plant components represented by Kalanchoe, dandelion, horsetail, lemon balm, plantain.

In order to avoid possible complications of self-treatment, it is better to entrust the removal of papillomas to specialists., which in stationary conditions affect growths:

• liquid nitrogen, which involves freezing papillomas (cryodestruction);
• with a regular scalpel (surgical excision);
• a laser that provides painless removal and prevents the reappearance of formations;
• radio waves.

Local treatment must be supplemented with antiviral drugs (Isoprinosin, Gosprinosin, Allokin Alpha), as well as pharmaceutical drugs with an immunostimulating effect, among which it is recommended to give preference to Immunal, Reaferon and Estifan.

Types of pathogens with a low risk of developing cancer

Important! Low-oncogenic HPV types, which in extremely rare cases cause cancer, include: 6, 11, 14, 42, 44, 53, 54.

As medical practice shows, HPV 6 and 11 are most often diagnosed in women.

Diagnostics

Like any other type of papillomavirus, the listed varieties with low oncogenic risk can only be identified based on the results of a comprehensive cytological study.

As for external manifestations, when examining a woman on a gynecological chair, a gynecologist can detect characteristic formations with pointed edges. The growths are localized mainly on the cervix and must be deleted.

Therapy

If the cause of the appearance of characteristic growths on the body is HPV infection of a low-oncogenic type, Preference in treatment is most often given to medications, because the risk of cancerous degeneration of formations is incredibly low.

In this case, you can use Solcoderm, Solkovagin, Panavir, Cryopharma, Imiquad, Condyl, Viferon and other effective analogues. And in this case, it remains mandatory to supplement local therapy with antiviral drugs (Panavir, Isoprinosine, Gosprinosine, Cycloferon, Genferon) and immunostimulating drugs (Galavit, Immunal, Likopid).

Reference! Low-oncogenic HPV types are not particularly dangerous.

In the treatment of their manifestations, folk remedies can be used, as well as various modern techniques for removing papillomatous growths on an outpatient basis, which have already been mentioned above.

But we must remember that any rash actions are a risk, since they can provoke a deterioration of the condition, therefore, when identifying warts, papillomas and condylomas, it is imperative to consult a specialist.

Here is a short video on this topic: