Irunin from thrush. "Irunin": treatment regimens and effectiveness for fungus Tablets from thrush Irunin

When thrush occurs, most women try to self-medicate. They often buy pills they saw on TV. Incorrectly selected drugs can only increase the manifestations of the disease, causing a lot of discomfort.

What is Trichopolum?

The tool is available in three types:

  • tablets for internal use;
  • vaginal tablets (candles);
  • solution for intravenous use.

Tablets quickly dissolve and are absorbed into the gastrointestinal tract. The maximum effect of the drug is achieved after 3 hours.

Before taking the drug, you should consult a doctor and undergo a thorough examination.

Tablets can be prescribed for such diseases:

  • trichomoniasis;
  • chlamydia;
  • gonorrhea;
  • stomach ulcer;
  • peritonitis;
  • endomentritis;
  • vaginitis;
  • cystitis;
  • skin infections;
  • sepsis;
  • postoperative period.

Treatment of thrush with Trichopolum in women is possible only after a doctor's prescription and if candidiasis is caused by a concomitant disease that is sensitive to the drug.

Trichopolum use for thrush in women

The instruction indicates that the drug is insensitive to fungi and infections. Therefore, this is not the best remedy for thrush in women. On the contrary, the drug can cause a weakening of the immune system and thereby provoke candidiasis.

The question arises for backfilling: “Why is Trichopol prescribed for thrush and how to take it?” The answer is obvious. Candidiasis is often caused or accompanied by other diseases, such as vaginosis or chladymiosis. As a rule, in such a situation, the doctor prescribes a complex treatment, where Trichopolum fights bacteria familiar to him, and another drug fights candidiasis.

Many specialists prescribe the drug before surgery. The radical procedure significantly reduces the protective functions of the immune system, and this can cause thrush. In this case, complex treatment should also be used.

Contraindications for use

The release form of the drug is prescribed by the doctor, taking into account the disease.

Trichopol is contraindicated:

  • in the first 12 weeks of pregnancy;
  • during the lactation period;
  • if coordination is impaired;
  • with blood diseases;
  • with an allergic reaction to the components of the drug and their individual intolerance;
  • with diseases of the central nervous system;
  • with liver failure.

Adverse reactions to the drug

If, after taking the remedy, a woman notices manifestations of side effects in herself, you need to stop taking the medicine and consult a doctor.

Adverse reactions that can be caused in women by taking Trichopolum:

  • vomiting and nausea;
  • excessive dryness of the oral mucosa;
  • constipation or diarrhea;
  • headache;
  • convulsions;
  • insomnia;
  • skin rashes;
  • active manifestation of symptoms of candidiasis;
  • redness and burning in the vagina.

In case of overdose, vomiting and convulsions are possible.

Instructions for use

Trichopol in the form of vaginal tablets is prescribed for women. They should be inserted deep into the vagina. Before use, the tablet must be moistened in boiled water.

With a complex course of therapy for thrush and a concomitant disease that is sensitive to the drug, Trichopolum is injected into the vagina 1 tablet per day, preferably at bedtime, and 1 tablet is also taken orally. Course - 10 days. It is forbidden to use Trichopol for more than 10 days and more often 3 times a year.

It is better to administer the tablet after the end of menstruation. But in severe and advanced cases, the doctor may prescribe the use of medication during menstruation.

Additional information about the drug

Taking the drug for women is allowed after the 12th week of pregnancy, when the internal organs of the fetus are already formed. Be sure to consult a doctor who will calculate the possible risks to the mother and fetus.

If Trichopol is prescribed for the treatment of vaginitis in women, then it is necessary to take antifungal drugs in the prevention of thrush.

As a rule, doctors can prescribe a combination: Trichopolum and Nystatin. So you can overcome the chronic and recurrent form of thrush. But this combination is a bit outdated, as there are more effective analogues in modern medicine.

Trichopol's analogs

Like many other drugs, Trichopolum has modern and no less effective analogues:

  • Deflamont;
  • Metrovit;
  • Klion;
  • Rosex;
  • Trichosept;
  • Metronidal;
  • Metronidazole;
  • Flagyl;
  • Efloran.

They are available in different forms and dosages. Each of them contains detailed and understandable instructions for use in the package. The price may be much lower. A substitute can be any drug that contains metronidazole in its composition.

Detailed information on whether Trichopolum can be used in the treatment of thrush or not, how to use it correctly and in what cases, women can always be provided by a competent specialist.

And some secrets...

Have you ever tried to get rid of thrush? Judging by the fact that you are reading this article, the victory was not on your side. And of course, you know firsthand what it is:

  • white curdled discharge
  • severe burning and itching
  • pain during sex
  • bad smell
  • discomfort when urinating

Now answer the question: does it suit you? Can thrush be tolerated? And how much money have you already “leaked” for ineffective treatment? That's right - it's time to end it! Do you agree? That is why we decided to publish an exclusive article by our subscriber, in which she revealed the secret of her getting rid of thrush. Read article…

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Irunin is a drug created for the local and systemic treatment of fungal diseases caused by a wide range of pathogens (trichophytosis, yeast and yeast-like fungi, etc.).

Manufacturer

Veropharm (RF).

Approximate price of the drug

Analogues

Substitute analogues:

  • orungal,
  • Itrazol,
  • Itroconazole,
  • Itroconazole-Ratiopharm,
  • Orungamine.

It is released from the pharmacy by prescription.

Shelf life: 2 years

Compound

  1. The active substance is itraconazole, a synthetic derivative of triazole. The action of the substance blocks the normal synthesis of the fungal wall (a block in the synthesis of erosterol), which leads to the death of the fungal cell;
  2. Inactive substances, the composition of which varies depending on the form of release of Irunin (capsules or vaginal tablets) - white petrolatum, titanium oxide, dispersed starch, etc.

Indications for use

Indications for the use of Irunin are various fungal skin lesions of various localization in cases of ineffective treatment with other drugs; deep systemic mycoses, which are accompanied by severe lesions of the mucous membranes and skin; systemic mycoses that are not amenable to pre-treatment with other drugs; candidiasis (including candidiasis of the internal organs).

The dosage of Irunin, the duration of the course of treatment, the frequency of administration (application) is determined only by the doctor! Do not self-medicate, even in cases of your confidence in the rightness.

Brief annotation to the appointment

  • Capsules. In such cases, it is necessary to take Irunin at the same time as eating, drinking plenty of water. The average dose is 200 mg 2 times a day. The average course of treatment, depending on the disease, can vary from 7 days to one and a half months;
  • How to use Irunin in the form of vaginal tablets - tablets are inserted into the vagina 2 times a day for 5-7 days. Further course of treatment is agreed with the attending physician.

Irunin from thrush

Irunin is not the drug of first choice for the treatment of thrush in both women and men. Currently, this drug is a first-line drug in cases of systemic (with damage to internal organs) candidiasis. However, in some cases its use is justified. In such cases, apply 1 vaginal tablet 2 times a day for 7 days while taking 200 mg of Irunin 1 time per day for 2 weeks.

Contraindications for use

Irunin's contraindications are intolerance to the components of the drug (allergy), pregnancy (especially the 1st trimester).

Side effects

Side effects of Irunin when using local forms (vaginal tablets) are quite rare. The drug acts locally, it is not absorbed into the general bloodstream, which determines only the local side effects of the drug:

  • Itching, unexpressed burning sensation at the injection site (vagina);
  • Extremely rarely - allergic reactions.

Cases of drug overdose are not described.

However, when prescribing Irunin tablets, the following side effects are possible:

  1. Nervous system disorders (sleep cycle disorder, headaches, paresthesia, dizziness);
  2. Nausea, abdominal pain, loss of appetite, vomiting, rarely - toxic hepatitis, acute liver failure;
  3. Violation of blood clotting, decreased libido, menstrual irregularities;
  4. The appearance of edema, an increase in the level of potassium in the blood serum;
  5. Against the background of taking Irunin, decompensation of heart failure or chronic kidney disease is possible.

Special instructions for use

  • Irunin is prescribed with great care during pregnancy, lactation (breastfeeding), children under 12 years of age.
  • The use of Irunin is not addictive.
  • The simultaneous use of alcohol and Irunin tablets is not recommended due to the simultaneous metabolism by liver enzymes.

An alternative to coffee and tea in the treatment of thrush

The diet in the treatment of thrush is quite strict, with a long list of foods that are prohibited. However, the most difficult thing on a diet is not to give up fast food, fruits or alcohol, but morning coffee.

There are a number of reasons why coffee and tea should be avoided. Luckily, there are also some very good alternatives that can be used to replace caffeine. Below are a few options that you can use to ease your path to recovery from thrush.

Why Should Thrush Sufferers Avoid Caffeine?

Unfortunately, caffeine is one of the elements that should definitely be avoided. The good news is that caffeine is really not that good for human health, so getting rid of the habit of drinking coffee or tea can be a great favor for the whole body.

First, caffeine depletes the immune system by complicating the work of the adrenal glands. Every time a person drinks coffee, it stimulates the adrenal glands to produce adrenaline. If this is done several times a day for several years, the adrenal glands will quickly wear out. When this happens, the adrenal glands are unable to do their regular job in the right way, namely regulating hormone levels in the body. This can lead to symptoms such as weight gain, sleep disturbances. It is important to note that the immune response of the body is also weakened, therefore, the defense against Candida fungi falls.

Second, caffeine also causes a dramatic increase in blood sugar, fueling the growth of Candida. In 2008, a study found that caffeine increased blood sugar levels by as much as eight percent. And this effect was more pronounced after eating. As you know, sugar is the only thing that really needs to be avoided with thrush, because it feeds the Candida fungi and promotes their growth.

And finally, thirdly, coffee can also contain mold, which can cause an allergic reaction in those already suffering from Candida. If you leave the coffee beans for a long time, you can see the appearance of a light green or white coating with mold. This is a type of mold that often lives on coffee. Most teas also contain mold, so you need to be very careful when choosing your coffees and teas.

While decaffeinated coffee is certainly better than regular coffee, it still contains a small amount of caffeine. In an attempt to find a replacement for your morning drink, you need to look a little further.

So what are the alternatives?

Coffee Chicory

The chicory root is dried, roasted and ground to make a delicious bitter drink that is not so different from real coffee. Luckily, chicory root is also an excellent prebiotic (it contains 20% inulin), so it may even help populate the gut with healthy bacteria. Finally, the bitter taste stimulates the production of enzymes that help regulate the digestive system.

herbal teas

Herbal teas are another alternative, but care must be taken when choosing such teas. Be careful to choose your herbal tea carefully to purchase it without mold, as this will only feed Candida. One of the best options is nettle leaf tea, which contains antioxidants, vitamin C, and iron. It also helps improve circulation, which helps clear toxic Candida products from the body faster. You can also try cinnamon tea, chamomile tea, mint tea, ginger tea, or licorice tea. All of them have antifungal properties that will help in the fight against thrush.

Coconut oil

It may not be a drink, but it deserves a mention as it is an integral part in the treatment of thrush. Even better, it will give you a boost of energy! In addition to its natural antifungal properties, coconut oil also contains a unique form of saturated fat. The body does not store them, as it does with other fats - instead, it uses them as an energy source. You need to start with 1-2 tablespoons a day and monitor your well-being.

Tablets Irunin inhibits (breaks) the synthesis of ergosterol, which is an important component of the cell membrane of fungi, which causes the antifungal effect of the drug.

Irunin is active against dermatophytes (Trichophyton spp., Microsporum spp., Epidermophyton floccosum), Candida spp. (including Candida albicans, Candida glabrata, Candida krusei), molds (Cryptococcus neoformans, Aspergillus spp., Histoplasma spp., Paracoccidioides brasiliensis, Sporothrix schenckii, Fonsecaea spp., Cladosporium spp., Blastomyces dermatidis).

Indications for use

Indications for the use of Irunin are various fungal skin lesions of various localization in cases of ineffective treatment with other drugs; deep systemic mycoses, which are accompanied by severe lesions of the mucous membranes and skin; systemic mycoses that are not amenable to pre-treatment with other drugs; candidiasis (including candidiasis of the internal organs).

Mode of application

Inside, immediately after a meal, the capsules are swallowed whole.

With vulvovaginal candidiasis - 200 mg 2 times a day for 1 day or 200 mg 1 time per day for 3 days; with pityriasis versicolor - 200 mg / day for 7 days; with candidiasis of the oral cavity - 100 mg 1 time per day for 15 days, with ringworm of smooth skin - 200 mg / day for 7 days or 100 mg / day for 15 days (if the skin of the hands and feet is affected, additional treatment is carried out in that same dose for 15 days); with fungal keratitis - 200 mg 1 time per day for 21 days; with onychomycosis - 200 mg / day for 3 months or 200 mg 2 times a day for 1 week in repeated courses; in case of damage to the toenails (regardless of the presence of damage to the nails on the hands), 3 courses of treatment are carried out for 1 week, with an interval of 3 weeks. When the nails are affected only on the hands, 2 courses of treatment are carried out for 1 week, with an interval of 3 weeks. With systemic aspergillosis - 200 mg / day for 2-5 months; if necessary, the dose is increased to 200 mg 2 times a day. With systemic candidiasis - 100-200 mg once a day for 3 weeks - 7 months; if necessary, the dose is increased to 200 mg 2 times a day. With systemic cryptococcosis without signs of meningitis - 200 mg 1 time per day, maintenance therapy - 200 mg 1 time per day, duration of treatment - from 2 months to 1 year. With cryptococcal meningitis - 200 mg 2 times a day. With histoplasmosis - an initial dose of 200 mg 1 time per day, followed by an increase in the frequency of administration up to 2 times a day for 8 months. With sporotrichosis - 100 mg 1 time per day for 3 months; with paracoccidioidomycosis - 100 mg 1 time per day for 6 months; with chromomycosis - 100-200 mg 1 time per day for 6 months; with blastomycosis - from 100 mg 1 time per day to 200 mg 2 times a day for 6 months.

Side effects

Side effects of Irunin when using local forms (vaginal tablets) are quite rare. The drug acts locally, it is not absorbed into the general bloodstream, which determines only the local side effects of the drug:

  • Itching, unexpressed burning sensation at the injection site (vagina);
  • Extremely rarely - allergic reactions.

Contraindications

Irunin's contraindications are intolerance to the components of the drug (allergy), pregnancy (especially the 1st trimester).

Interaction with other drugs

Simultaneous use with rifampicin, rifabutin and phenytoin, which are strong inducers of microsomal liver enzymes, is not recommended. these drugs can significantly reduce the bioavailability of itraconazole and hydroxyitraconazole, which leads to a significant decrease in the effectiveness of the drug. Studies on the interaction of itraconazole with other inducers of liver enzymes, such as carbamazepine, phenobarbital and isoniazid, have not been conducted, but a similar effect can be assumed. Because Itraconazole is mainly metabolized with the participation of the CYP3A4 isoenzyme of the cytochrome P450 system, strong inhibitors of this enzyme (including ritonavir, indinavir, clarithromycin and erythromycin) may increase the bioavailability of itraconazole. Itraconazole can inhibit the metabolism of drugs that are biotransformed with the participation of the CYP3A4 isoenzyme. The result of this may be an increase or prolongation of their action, incl. and side effects. After cessation of treatment, plasma concentrations of itraconazole decrease gradually, depending on the dose and duration of treatment. Simultaneously with itraconazole, terfenadine, astemizole, mizolastine, cisapride, triazolam, midazolam (oral), dofetilide, quinidine, pimozide, metabolized by the CYP3A4 isoenzyme, HMG-CoA reductase inhibitors (simvastatin and lovastatin) should not be prescribed. Calcium channel blockers have a negative inotropic effect, which may enhance the similar effect of itraconazole; itraconazole may reduce the metabolism of calcium channel blockers. Itraconazole should be used with caution concomitantly with calcium channel blockers. Drugs that require control of plasma concentrations: oral anticoagulants; HIV protease inhibitors (ritonavir, indinavir, saquinavir); some anticancer drugs (vinca rosea alkaloids, busulfan, docetaxel, trimetrexate); calcium channel blockers metabolized with the participation of the CYP3A4 isoenzyme (dihydropyridine and verapamil); some immunosuppressants (cyclosporine, tacrolimus, sirolimus); other drugs - digoxin, carbamazepine, buspiron, alfentanil, alprazolam, brotizolam, rifabutin, methylprednisolone, ebastine, reboxetine. With simultaneous use with itraconazole, if necessary, the dose of these drugs should be reduced. Interactions between itraconazole and zidovudine and fluvastatin have not been found. There was no effect of itraconazole on the metabolism of ethinylestradiol and norethisterone. In vitro studies have shown no interaction between itraconazole and drugs such as imipramine, propranolol, diazepam, cimetidine, indomethacin, tolbutamide and sulfamethazine when bound to plasma proteins.

Pregnancy

During pregnancy, Irunin is prescribed only in cases of emergency, when the expected benefit of therapy for the mother outweighs the existing risk to the fetus. Itraconazole is excreted in breast milk in small amounts. If it is necessary to prescribe the drug Irunin during lactation, the expected benefit of therapy for the mother and the potential risk to the infant should be carefully evaluated. If in doubt, consider stopping breastfeeding. Women of childbearing age during the period of Irunin use should use reliable methods of contraception during the entire course of treatment until the onset of the first menstruation after its completion.

Overdose

Data on an overdose of the drug Irunin are not available.

Treatment: in case of accidental overdose within the first hour after taking the drug, gastric lavage should be done, if necessary, activated charcoal should be prescribed.

Symptomatic and supportive therapy is indicated. Itraconazole is not excreted by hemodialysis. The specific antidote is not known.

Storage conditions

In a dry, dark place, at a temperature not exceeding 25°C.

Release form

Tablets vaginal cream (200 mg active substance) 10 pcs. packaged.

Capsules 100 mg 6, 10, 14 pieces per pack.

Compound

The active substance is itraconazole, a synthetic derivative of triazole. The action of the substance blocks the normal synthesis of the fungal wall (a block in the synthesis of erosterol), which leads to the death of the fungal cell.

Inactive substances, the composition of which varies depending on the form of release of Irunin (capsules or vaginal tablets) - white petrolatum, titanium oxide, dispersed starch, etc.

There are many drugs for the treatment of vaginal candidiasis. Irunin is one of them. Schemes have been developed on how to take Irunin for thrush, they should be selected individually by the attending physician.

What is Irunin

The active ingredient in Irunin is itraconazole. Each capsule (round coated microgranules) contains 100 mg of this substance. In addition to the main substance, Irunin contains hypromellose, eudragit, nilagin, nipazole, sucrose, starch. Yellow capsules filled with white pellets.

Candles or vaginal tablets of the drug contain 200 mg of the active substance, since it is more difficult for it to penetrate through the mucous membranes. Additionally, there are starch, titanium oxide, white petrolatum.

Intraconazole is a synthetic substance, one of the triazole derivatives. This is a broad-spectrum drug directed against pathogens of fungal infections. It is insoluble in water and alcohol and is fat soluble.

This substance inhibits the synthesis of one of the components of the cell membrane of the fungus (ergosterol), preventing its reproduction. Dermatophytes, yeast-like fungi, yeast, aspergillus, histoplasma, pathogens of paracoccidiosis and candidiasis (C.albicans, C.krusei, C.giabrata) and other mold and yeast fungi are sensitive to it.

Capsules are taken only after a heavy meal, when the drug is best absorbed into the blood and after 3-4 hours reaches the highest concentration in the blood plasma. It is excreted from the body within 2-3 days. But in the vaginal mucosa, the substance remains for 2 weeks after the end of the course of treatment and for 3 days if the drug was taken only twice in one day.

The use of Irunin for candidiasis

For the treatment of vulvovaginal candidiasis, capsules, vaginal tablets or suppositories are used.

Vulvovaginal thrush is a lesion of the mucous membranes of the vagina and its vestibule with spores of fungi of the genus Candida, which is accompanied by cheesy discharge of white or gray color, itching and burning in the vulva, pain during urination and sexual intercourse.

Provoking factors are taking antibacterial or hormonal drugs, diabetes, improper intimate hygiene. If thrush is complicated by other fungal diseases or if it is difficult to make a diagnosis, broad-spectrum drugs, such as Irunin, are prescribed.

As already mentioned, Irunin capsules should be drunk only after meals and as a whole. Opening capsules and extracting pellets is unacceptable.

The dose in the treatment of thrush is 2 capsules of 100 mg at a time twice a day. If there is a relapse, you should take the drug 2 capsules for 1 dose 1 time per day for 3 days. This will ensure a longer stay of the therapeutic concentration of the drug in the blood plasma and in the mucous membranes of the vulva and vagina.

With reduced acidity of gastric juice, Irunin may partially lose its effectiveness due to impaired absorption of itraconazole. Therefore, if the patient, in addition to drugs for thrush, is forced to drink drugs that neutralize hydrochloric acid or anticholinergics, she can drink Irunin only 2 hours after taking antacids. If Introconazole must be combined with histamine receptor blockers, the capsules of the drug from thrush should be drunk with Coca-Cola.

People with immune deficiency (AIDS patients or neutropenic patients who have had an organ transplant) may need an increased dose of the drug or an extension of the course of treatment.

Vaginal suppositories or Irunin tablets are used once a day, at bedtime, after intimate hygiene and douching, to remove cheesy secretions characteristic of candidiasis. The drug is injected as deep as possible into the vagina, in the supine position, the course of treatment is 5-7 days. The end of the course is carried out only by the decision of the attending physician after examination. He also decides to extend the course to 14 days. Clinical manifestations of thrush (itching and discharge) recede already on the second day of treatment. At the onset of menstruation, suppositories are replaced with oral capsules.

Contraindications and side effects

Possible side effects from the digestive system:

Side effects related to the nervous system:

  • dizziness;
  • headache;
  • peripheral neuropathy.

People with a history of diabetes mellitus, allergies to any of the components of the drug, heart, kidney or liver failure, it is recommended to choose another medicine for the treatment of candidiasis. It is also undesirable to drink the drug for pregnant women, nursing mothers are not prescribed Irulin because of its ability to penetrate into milk.

Possible side effects include dysmenorrhea, hypocalcemia, alopecia, dark urine, hypercreatininemia, edema, and fatigue.

Simultaneous administration of the drug Irunin and Terfenadin, Mizolastin, Cisapride, Dofetilide, Miconazole, Astemizole, Quinidine and Triazolam, which are absorbed with the participation of the cytochrome P450 3A4 enzyme, as well as indirect coagulants such as Cyclosporine A, Methylprednisolone and Digoxin, enhances and prolongs the action of the latter.

Cytochrome inhibitors, such as Indinavir, Ritonavir and Clarithromycin, increase the bioavailability of Irunin, and oxidation stimulators in liver cells, such as Isoniazid, Rifampicin and others, reduce it.

It is forbidden to combine Irunin with Cisapride, since the toxicity of the latter increases, it becomes possible to develop gastric arrhythmias.

Do not forget that banal thrush is often a complication of the underlying, more dangerous disease, so effective treatment of candidiasis should begin with a complete examination of the patient to identify complicating and provoking factors.

Irunin tablets are an antifungal agent for topical use in the field of gynecology. Below is an instruction for the use of this dosage form of the drug.

Composition and pharmacological action

The active substance is itroconazole (200 milligrams per tablet).

Itroconazole has an antifungal effect due to the fact that under its influence the cell membrane of pathogenic fungi becomes less durable and gradually collapses. This result is achieved due to the fact that itroconazole inhibits the production of ergosterol (a precursor of vitamin D2), which is an integral part of the fungal cell wall.

As excipients, Irunin contains the following components: milk sugar, Mg3C4O3, potato starch, sodium dodecyl sulfate, insoluble polyvinylpyrrolidone, stearic acid.

Analogues

Analogues of Irunin containing the same active substance (itraconazole) are the following drugs:

  • Itramikol;
  • (for pregnant);
  • Canditral;
  • Myconihol;
  • Orungamine;
  • Teknazol.

Release form

Irunin vaginal tablets are in the form of a ring. White or whitish. Are issued on 10 pieces in cardboard packing.

In addition to vaginal tablets, there is such a dosage form of Irunin as capsules for oral (oral) use. It is released from pharmacies by prescription. The average price of Irunin in Russia is 315 rubles per package (10 tablets).

Indications for use

Irunin in the form of tablets is prescribed for the treatment of vulvovaginal candidiasis (thrush) of varying severity. Including effectively helps with recurrent thrush.

Instructions for use

Irunin tablets are intended for intravaginal use.

The description below explains how to take Irunin tablets for thrush.

The duration of the course of treatment is usually 1-2 weeks. If necessary, the doctor may prescribe repeated courses of treatment.

To prevent relapse, sexual partners should be treated at the same time, refrain from sexual intercourse for the period of treatment and observe personal hygiene.

Contraindications

Treatment with the drug Irunin tablets is contraindicated in the presence of the following conditions:

  • intolerance to the active substance and / or auxiliary components of the drug;
  • first trimester of pregnancy and lactation.

Use with caution and exclusively under the supervision of a specialist during the second and third trimesters of pregnancy.

If necessary, the use of the drug during lactation should stop breastfeeding.

Drug interaction of Irunin vaginal tablets with other drugs has not been identified.

Cases of overdose with intravaginal use have not been recorded. Excessive oral use of dosage forms intended for oral use does not threaten the life and health of the drug.

If you accidentally swallow a tablet intended for intravaginal use, rinse your stomach with warm water or a weak solution of baking soda, then take some enterosorbent (for example, activated charcoal).

Side effects

With intravaginal use, local allergic reactions may occur - rashes, discomfort in the vagina (itching, burning).

Expert opinion

Dermatologist Shcherban A.V.:

A very effective antimycotic agent. I usually prescribe for systemic therapy, most often for onychomycosis (except for distal, that is, onychomycosis of the free edge of the nail). Of course, it has contraindications and side effects, but this is normal for antimycotics of this kind. So Irunin fully justifies its price.

Thrush is an infectious-inflammatory disease that affects the area of ​​​​the external and internal organs. The causative agent of the presented disease are yeast-like fungi of the Candida family.

For effective treatment of thrush, antimycotic drugs are used to help suppress the growth of pathogens and stop the development of the pathological process.

Irunin is considered one of the most effective and popular medicines of this pharmacological group. Let us consider in more detail the clinical properties and features of the use of the presented drug for thrush.

Characteristics and pharmacological properties

Irunin belongs to the pharmacological group of antimycotic, antifungal drugs with a wide range of applications. The main active ingredient is itraconazole. This component has a pronounced antibacterial effect, and also has the ability to destructively affect the cell membrane of Candida family fungi, which ensures the maximum effectiveness of Irunin in the treatment of thrush. Also, the composition of the drug includes the following substances:

Also, the drug is extremely effective in the fight against dermatophytes and mold fungi.

The presented drug not only helps to cope with pathogens, but also helps to restore normal microflora in organs affected by fungi.

The maximum clinical effect is observed after two to three weeks of the therapeutic course.

Release form and cost

Irunin is produced in capsules intended for internal use, as well as in the form of vaginal suppositories, designed specifically to combat vulvovaginal candidiasis. The cost of the drug is quite democratic and affordable for most buyers.

In pharmacies, you can buy packages of Irunin for oral administration, containing six, ten or fourteen tablets. The cost of one package in Moscow ranges from 437 to 840 rubles. A pack of six vaginal suppositories will cost about 330 rubles. In pharmacies in St. Petersburg, the price of Irunin will be slightly lower.

So, the cost of one package of capsules is from 400 to 750 rubles (depending on the number of tablets). Vaginal suppositories can be purchased at a price of 310 rubles per package.

The drug has the following analogues:

  1. Orungal - 350-400 rubles.
  2. Orungamine - 600-700 rubles.
  3. Itrazol - 400 rubles.

Indications

Irunin is a very effective drug, characterized by a wide spectrum of action. Therefore, the presented drug is actively used in the field of modern medicine to combat the following diseases:

As for the vaginal tablets "Irunin", they are used exclusively for the treatment of vaginal candidiasis. The presented form of release allows you to achieve the maximum concentration of the active substance in the lesion, preventing active entry of the drug into the blood.

Contraindications and restrictions

Despite the marginal effectiveness of Irunin, in some cases it is categorically not recommended to take the presented drug. The main contraindications include the following:


Irunin capsules should not be taken by pregnant women and nursing mothers.

Vaginal suppositories for these categories of patients are prescribed by a doctor only in extreme cases, when the benefits of the drug for the mother largely outweigh the possible risks to the health of the child. In this case, the therapeutic course should take place under the strict supervision of a specialist.

Side effects

In some cases, the drug in question can provoke the development of the following adverse reactions:

When using vaginal suppositories, the following manifestations are possible:

  1. Burning sensation and discomfort in the vaginal area.
  2. Skin rashes localized in the area of ​​​​the external genital organs.

It should be emphasized that in most cases the development of the above side effects is observed with prolonged and uncontrolled intake of Irunin.

In order to avoid the occurrence of adverse reactions and reduce the risks to a minimum, the presented drug should be used exclusively as prescribed by the doctor, strictly following his recommendations!

Application rules

Various diseases of a fungal nature suggest a special scheme for the use of Irunin. Let us consider in more detail how to take the presented medication for thrush.

Many of our readers THRUSH TREATMENT(candidiasis) are actively using a new method based on natural ingredients, which was discovered by Olga Larina. It contains only natural ingredients, herbs and extracts - no hormones or chemicals. To get rid of thrush you need every morning on an empty stomach ...

According to the annotation, Irunin is taken one tablet after meals, twice a day. The duration of the therapeutic course is from one to three days. However, this is just a general outline. A qualified specialist selects the optimal dosage and duration of treatment individually, in each case.

This takes into account factors such as the degree of candidiasis, the age category and body weight of the patient, his general health, the presence or absence of concomitant diseases. So, for example, patients with impaired functioning of the immune system may need to increase the dosage to achieve a therapeutic effect.

Vaginal suppositories are inserted into the vagina once every two days. The duration of treatment is on average about two weeks, depending on the severity and stage of development of candidiasis, as well as on the individual characteristics of the patient.

Women of reproductive age should use contraceptives during the therapeutic course until the next menstrual cycle.

The use of Irunin allows you to quickly and effectively eliminate the painful symptoms characteristic of thrush, which makes this drug especially popular in the fight against vaginal candidiasis.

Are you still sure that it is impossible to GET RID OF THE THRUSH FOREVER?

Have you ever tried to get rid of THRUSH? Judging by the fact that you are reading this article, the victory was not on your side. And of course, you know firsthand what it is:

  • white curdled discharge from the external genitalia ...
  • itching and burning in the vaginal area ...
  • sour smell...
  • pain and discomfort when urinating, during intercourse...

Now answer the question: Are you satisfied with this? Can thrush be tolerated? And how much money have you already "leaked" for ineffective treatment? That's right - it's time to end it! Do you agree? That is why we decided to publish the exclusive story of Irina Kravtsova, in which she revealed the secret of her FAST getting rid of thrush.