Panangin for intravenous administration. Panangin - instructions for use

pharmacodynamics. Potassium and magnesium ions, as important intracellular cations, are involved in the work of a number of enzymes, in the process of binding macromolecules with subcellular elements and in the mechanism of muscle contraction at the molecular level. The ratio of extra- and intracellular concentrations of potassium, calcium, sodium and magnesium ions affects myocardial contractility. Aspartate, as an endogenous substance, is a carrier of potassium and magnesium ions; has a pronounced affinity for cells, its salts undergo dissociation only slightly. As a result, ions penetrate into the intracellular space in the form of complex compounds. Magnesium and potassium aspartate improves the metabolism of the heart muscle. Insufficient intake of potassium and magnesium into the body contributes to the development of hypertension and pathology coronary vessels sclerotic type, heart rhythm disturbances, myocardial degeneration.

Pharmacokinetics. Not studied.

For complementary therapy at chronic diseases heart (with heart failure, in the post-infarction period), cardiac arrhythmias, especially ventricular arrhythmias.

Additional therapy during treatment with digitalis preparations.

Panangin is prescribed exclusively intravenously.

Adults are administered slowly IV drips of 10-20 ml (the contents of the ampoule are diluted in 50-100 ml of 5% glucose solution). This dose can be re-administered after 4-6 hours if necessary.

The drug is suitable for combination therapy.

The course of treatment is determined by the doctor.

increased sensitivity To active substance or any of excipients drug. ARF and chronic renal failure. Addison's disease. AV block of the third degree. Cardiogenic shock (BP)<90 мм рт. ст.).

with rapid administration of the drug, symptoms of hyperkalemia/hypermagnesemia may occur.

rapid administration may cause facial flushing.

Panangin, as a drug containing potassium and magnesium, should be used with caution in patients with myasthenia gravis; in conditions that can lead to hyperkalemia, such as acute dehydration, extensive tissue damage, including severe burns. In this category of patients, it is recommended to regularly examine the level of electrolytes in the blood plasma.

During pregnancy and breastfeeding. To date, no danger has been reported when using the drug in this category of patients.

Children. There is insufficient experience with the use of the drug in children.

The drug does not affect ability to drive vehicles and operate complex mechanisms.

when used simultaneously with potassium-sparing diuretics and/or ACE inhibitors, the risk of developing hyperkalemia increases.

cases of overdose are unknown. In case of overdose, symptoms of hyperkalemia and hypermagnesemia can be observed.

Symptoms of hyperkalemia: general weakness, paresthesia, bradycardia, paralysis. Extremely high concentrations of potassium in the blood plasma can lead to death from cardiac depression, arrhythmia, or cardiac arrest.

Symptoms of hypermagnesemia: nausea, vomiting, drowsiness, hypotension, bradycardia, weakness, slurred speech, double vision. At very high plasma concentrations of magnesium, hyporeflexia, muscle paralysis, respiratory arrest and cardiac arrest may occur.

In case of overdose, K + -, Mg 2+ -aspartate must be discontinued and symptomatic treatment is recommended (calcium chloride 100 mg/min IV, dialysis if necessary).

at a temperature not exceeding 30 °C.

Panangin contains a number of microelements necessary for the body - the instructions for use indicate that it is used for convulsions, high blood pressure, decreased myocardial contractility and vascular spasms caused by the influence of potassium and magnesium in insufficient quantities. This drug replenishes their supply. Potassium and magnesium are contained in the medicine in an easily digestible form, so it is highly effective. Their combination is due to the fact that the lack of one of the elements is often accompanied by a lack of the other.

The preparation is based on 2 microelements – magnesium and potassium ions. Due to them, the medicine normalizes heart rhythm, further improving the conduction of nerve impulses through the conduction system of the heart. Restoring ion levels by eliminating magnesium and potassium deficiency helps with heart rhythm disturbances. Such effects help in the treatment or prevention of atherosclerosis and myocardial infarction. Panangin - instructions for its use indicate that it is part of a combination therapy against the occurrence of arrhythmia or chronic heart diseases.

Compound

Regardless of the form of release, the main substances of the drug are potassium and magnesium. The composition contains auxiliary components. They are different for tablets and solution, in the form of which the drug is produced. The table describes the composition in more detail:

Release form

Panangin is available in different forms - in the form of an injection solution and tablets for oral administration. The active substances in them are the same, but are contained in different concentrations. In a pharmacy, each form of the drug can be recognized by its special packaging and the type of tablets or solution themselves:

Pharmacodynamics and pharmacokinetics

Magnesium and potassium are very important for the formation of connections between macromolecules and intracellular structures, the preservation of myocardial functions, and muscle contraction. Substances help:

• restore electrolyte balance;
• regulate metabolic processes and reactions;
• prevent the development of arrhythmia due to low levels of potassium and magnesium.

Potassium is an integral part of synaptic transmission, the implementation of muscle contractions. Its aspartate improves the conduction of nerve impulses. Additionally, the microelement has a diuretic effect. Magnesium is part of the reactions and processes responsible for energy expenditure. It promotes the penetration of potassium ions into cells. Medicine based on them improves myocardial metabolism. According to the instructions for use, the drug is well absorbed and excreted by the kidneys.

Indications for use

The main indication for use is to compensate for the deficiency of potassium and magnesium in the body. This is necessary for cardiovascular pathologies or the development of their complications. Specific indications, according to the instructions, are:

• heart failure;
• hypomagnesemia and hypokalemia with low magnesium content or lack of potassium in the diet;
• taking laxatives and diuretics, glucocorticosteroids;
• persistent vomiting, diarrhea;
• taking saluretics that enhance sodium excretion;
• acute myocardial infarction;
• digitalis intoxication;
• atrial extrasystole;
• paroxysmal tachycardia;
• supraventricular tachycardia;
• ventricular extrasystole.

Directions for use and dosage

The dosage of the drug is prescribed by the doctor, taking into account the disease and the nature of its course. The tablets are taken orally, and the solution is prescribed intravenously in the form of droppers. The latter method is used for a faster effect of the drug due to the fact that it enters the body bypassing the digestive system. After some time, the use of Panangin solution is stopped, and therapy is continued with oral administration of the tablet form.

Panangin tablets

The drug is prescribed orally, 2 tablets up to 3 times a day. Maintenance therapy has a different dosage. As a preventive measure, it is recommended to take 1 tablet 3 times a day for a course of up to 3-4 weeks. Sometimes a repeat cycle of therapy is required, but this can only be decided by a specialist. You need to take the medicine after meals, because the absence of food in the stomach reduces the therapeutic effectiveness of the drug.

This form of the drug is intended for slow infusion of a solution of approximately 20 drops per minute. The dosage is 1-2 ampoules, diluted with 50-100 ml of glucose or dextrose 5%. Panangin - instructions for use in this form allow it to be combined with other drugs for intravenous administration. A second dropper is placed 4-6 hours after the first infusion.

special instructions

The drug is poorly compatible with alcohol, because it is used in the treatment of the cardiovascular system. For this reason, it is important to abstain from all types of alcohol during treatment. Judging by the reviews, vasospasm may occur with the simultaneous use of alcohol and Panangin. Before starting therapy, the doctor should be warned about taking any other medications. The medication does not affect the functional state of the cerebral cortex, therefore it does not change the speed of psychomotor reactions and concentration.

Panangin for children

The dosage of the drug for children is slightly different. Intravenously it is 10 ml of Panangin, diluted with 100 ml of 5% glucose solution. The dosage of tablets is determined by the age of the child. It is 0.5 or 1 tablet, sometimes divided into 2-3 doses. According to the instructions, the drug is approved even for newborns, but the dosage in this case is determined only by the doctor.

Drug interactions

When taken with other antiarrhythmic drugs, Panangin enhances their dromotropic and bathmotropic effects. Anesthetics enhance the inhibitory effect on the central nervous system. Taking Panangin with atracuronium, decamethonium and succinyl chloride leads to increased neuromuscular blockade. Astringent or enveloping medications can reduce the absorption of potassium and magnesium. Panangin improves the tolerability of cardiac glycosides, as it is pharmaceutically compatible with their solutions. Other cases of interaction:

• calcium supplements reduce the therapeutic effect of Panangin;
• while taking potassium-sparing diuretics, heparin, cyclosporine, beta-blockers and ACE inhibitors, the risk of developing hyperkalemia increases;
• when taking Panangin, the effectiveness of streptomycin, polymyxin B, neomycin, and tetracycline decreases.

Side effects

Judging by reviews from cardiologists and patients, the use of Panangin in some cases may result in adverse reactions. They arise from different body systems. In general, these are the following side effects:

1. In relation to the cardiovascular system - paradoxical reactions, AV blockade.
2. On the part of digestion - discomfort in the epigastric region with antacid gastritis and cholecystitis, diarrhea, nausea, vomiting.
3. Water-electrolyte reactions - redness of the facial skin, hyperkalemia, hypermagnesemia, confusion, thirst, drop in pressure, respiratory depression.

Overdose

If the recommended dosage of the drug is exceeded, not only side effects may increase, but also other negative reactions may occur that are harmful to the body. In this case, hemodialysis or peritoneal dialysis and emergency administration of a solution of dextrose and sodium chloride are justified. Reactions after an overdose are:

• slowing of atrioventricular conduction;
• muscle hypotonicity;
• changes in the electrocardiogram;
• paresthesia of the limbs;
• cardiac arrest.

Contraindications

The medicine has a large list of restrictions, so be sure to read the instructions before using it. There are several common cases for both forms of release of the drug, but each of them also has a number of individual contraindications. The table describes them in more detail:

Terms of sale and storage

You can buy Panangin in any form without a prescription from a doctor. The medication must be stored in a dark place where it is inaccessible to children. The recommended temperature is 15-30 degrees Celsius. The shelf life of the drug is 5 years.

Panangin's analogs

There are drugs that are similar in composition or mechanism of action. Any analogue of Panangin has these characteristics, among which the following stand out.

• Magnesium aspartate;
• Potassium Aspartate;
• Biolectra Magnesium Fortissimum.

Panangina price

In specific pharmacies Panangin costs differently. The price is determined not only by the place of purchase, but also by the manufacturer, dosage and release form. The approximate cost of the medication is shown in the table:

Video

The drug Panangin belongs to the group of mineral agents that can have a protective effect on myocardial muscle fibers. When taken correctly, it helps prevent heart rhythm disturbances and the development of ischemic tissue damage due to oxygen starvation.

Helps eliminate the phenomena of heart failure and improper polarization of ions involved in energy metabolism. Use is indicated for confirmed deficiency of potassium and magnesium salts in the blood plasma.

Available in the form of tablets and solution for intravenous administration. The active ingredients are potassium aspartate and magnesium aspartate.

When introduced into the body either in tablet or infusion form, panangin is quickly absorbed into the blood and enriches it with potassium and magnesium ions. The importance of potassium for the health of the heart muscle cannot be overestimated. This microelement is responsible for the conduction of nerve impulses and the normalization of the membrane membranes of myocardiocytes and neurons. Thanks to this, a sufficient amount of potassium in the blood plasma is able to maintain the energy balance of the myocardium at a high level. In practice, this is expressed in the absence of rhythm disturbances and oxygen deficiency in oxidative processes. In patients with heart failure and in the period after acute myocardial infarction, potassium, which comes from food components, is not absorbed properly. A large number of extracellular forms of this substance arise. They gradually attract more and more potassium ions from the intracellular space, which stimulates the deterioration of the clinical picture. Intravenous administration of panangin in such cases helps eliminate this imbalance and restore metabolic processes in the myocardium.

The human body needs magnesium for the synthesis of various amino acids, on the basis of which proteins and cellular structures are built. This microelement is involved in various reactions in the production of enzymatic substances. When penetrating the myocytes of the heart muscle, magnesium reduces the number of contractions and has the ability to restore normal rhythm. There is also an effect aimed at reducing the phenomena of oxygen starvation and ischemia of muscle tissue. This also affects the smooth muscles of various blood vessels. Gradually, they dilate and restore normal blood flow.

Panangin solution and tablets - instructions for use

Panangin tablets are prescribed for oral administration. The duration of the course of treatment depends on the severity of the patient’s condition and can range from 15 days to 2-3 months. The drug should be taken after meals. This is necessary to reduce the risk of hydrochloric acid affecting the tablet shell.

The instructions for use recommend using Panangin solution for the preparation of mixtures for intravenous drip infusions. But you can also give intravenous injections. To do this, the panangin solution is diluted with saline in a ratio of 5 ml of panangin and 10 ml of 0.9% isotonic solution.

The preferred method is slow drip administration. In this case, the sick person should be in a supine position. Thus, more complete absorption of minerals is achieved.

What are Panangin's indications for use?

Treatment of any disease that requires the administration of panangin usually begins with intravenous administration of the drug. Injections are given every other day in an amount of 5 pieces. In the future, the patient is recommended to continue therapy with Panangin tablets.

Main indications for the use of panangin:

• long-term maintenance and replacement therapy with cardiac glycosides;
• arrhythmias of ventricular and atrial type;
• weakness of the sinus node;
• heart rate driver dissonance;
• cardiovascular failure in acute and chronic form;
• recovery period after myocardial infarction;
• cardiac ischemia;
• mineral deficiency.

Can Panangin be used during pregnancy and children?

It is recommended to use panangin during pregnancy if a woman has insufficient intake of microelements from her diet. Magnesium deficiency can manifest itself in the form of cramps in the calf muscles, discomfort in the heart and swelling of the ankle joints in the morning.

The drug Panangin is prescribed to children in similar cases. In the newborn period, indications for use may be insufficiency of the cardiac pacemaker function and increased convulsive readiness.

Pregnancy, breastfeeding and childhood are not contraindications for treatment with this pharmacological agent.

What are the contraindications and side effects?

Side effects can only occur if there is an excess amount of potassium and magnesium ions in the body of a sick person. In this case, complete withdrawal of the drug is sufficient to ensure that all unpleasant symptoms are eliminated.

The following diseases and conditions may be contraindications for the use of solution and tablets:

• individual intolerance to individual components;
• dysfunction of the urinary system;
• blockade of the heart muscle and pacemakers;
• states of shock;
• increased content of potassium and magnesium ions in the blood and plasma;
• dehydration and severe intoxication.

What analogues of panangin exist?

The only analogue of panangin is asparkam. Both drugs have identical composition to each other. However, for intravenous administration it is recommended to give preference to panangin, since asparkam is somewhat more difficult to tolerate in patients with weak heart muscles.

In tablet form, no significant differences were found between taking panangin and asparkam.

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Composition of tablets

Active substances: magnesium aspartate (140 mg) and potassium aspartate (158 mg).

Additional substances: silicon dioxide, corn and potato starch, talc, povidone, magnesium stearate. The shell consists of talc, macrogol 6000, titanium dioxide, methacrylic acid copolymer.

Concentrate for solution (Panangin IV)

pharmachologic effect

What is the medicine for? This is a source of potassium and magnesium. The drug promotes recovery electrolyte balance , regulates metabolic and metabolic reactions and processes, has a pronounced antiarrhythmic effect. Potassium takes an active part in synaptic transmission , in conducting nerve impulses through fibers, in carrying out muscle contractions, and maintains the normal functioning of the heart. When potassium metabolism is disturbed, the excitability of muscle tissue and nerves changes. Active ion transport maintains a high potassium gradient across the plasma membrane. Small dosages of potassium contribute to the expansion of the coronary arteries, and in large dosages the microelement narrows their lumen. Potassium has a moderate diuretic effect , negative bathmotropic and chronotropic influence. Magnesium is a cofactor in three hundred enzyme reactions. Magnesium is an essential element during processes and reactions that provide energy intake and expenditure. Magnesium is part of the pentose phosphate structure of DNA, takes part in the process of cell division and growth, the structure of heredity, and RNA synthesis; is a natural BMCA, prevents the release of free fatty acids and catecholamines during stress, and promotes the penetration of potassium ions into the cell. The drug has a stimulating effect on intercellular phosphate synthesis.

Mnn: potassium and magnesium aspartate.

Pharmacological group: potassium and magnesium preparation.

Pharmacodynamics and pharmacokinetics

The active substances play an important role in the formation of connections between macromolecules, as well as intracellular structures and the mechanism of muscle contraction and myocardial metabolism.

According to the annotation, the drug is well absorbed. Excreted through the kidneys.

Indications for use of Panangin

Panangin tablets - what are they for?

Indications for use of Panangin are as follows. The drug is prescribed for hypomagnesemia, hypokalemia , when taking laxatives and diuretics, glucocorticosteroids, with diarrhea, persistent vomiting, taking saluretics, with myocardial infarction, heart failure , digitalis intoxication, ventricular extrasystole , atrial extrasystole, supraventricular tachycardia, paroxysmal tachycardia.

Example of a recipe in Latin: Rp.: Dragee “Panangin” N. 20

Contraindications for Panangin

The drug is not used for intolerance to fructose, sorbitol, impaired metabolism, chronic pathology of the renal system, hemolysis, exicosis, dehydration, arterial hypotension , myasthenia gravis, hypermagnesemia, hyperkalemia, metabolic acidosis , Addison's disease. Panangin is used with caution during pregnancy.

Side effects

Side effects are the following manifestations: ulceration of the mucous wall of the digestive tract, epigastric pain, bleeding from the organs of the digestive system, falling, bradycardia, paradoxical reaction in the form of an increase in the number of extrasystoles, dry mouth, nausea, hyporeflexia, dyspnea, thrombosis, phlebitis, paresthesia, dizziness, increased sweating, asthenia , myasthenia gravis. With rapid intravenous infusion, hypermagnesemia and hyperkalemia are observed.

Instructions for use of Panangin (Method and dosage)

Panangin tablets, instructions for use

How to take the medicine? The drug is taken orally three times a day, 2 tablets. Maintenance and preventive therapy: 1 tablet three times a day, course for 3-4 weeks. In some situations, a repetition of the course of therapy is required.

Instructions for intravenous use

Panangin solution is injected intravenously, slowly. The drug is administered at a rate of 20-30 drops per minute, 1-2 times a day, 300 ml. Dosing of the drug Panangin during pregnancy is carried out according to the standard regimen of medication use.

Children can take the medicine from birth.

How to take Panangin for prevention?

If you ask the question of the benefits and harms of Panangin, you should realize that this is a drug that has its own side effects, so you should not use it for prevention. Firstly, in this way you accustom the body to a high content of magnesium and potassium, and secondly, you can provoke an overabundance of these substances, which in turn can cause a lot of negative reactions.

Overdose

Manifests muscle hypotonia , hyperkalemia, slowing atrioventricular conduction , cardiac arrest, arrhythmia , paresthesia of the limbs, changes in the electrocardiogram. An emergency intravenous infusion of a solution of dextrose and sodium chloride is required. If necessary, peritoneal dialysis is justified.

Interaction

Panagin is able to enhance the negative bathmotropic, dromotropic effects antiarrhythmic drugs . The medication eliminates hypokalemia, which develops against the background of long-term use of diuretics, glucocorticosteroids, and MCS. NSAIDs, ACE inhibitors, heparin, potassium-sparing diuretics, beta-blockers increase the risk of hyperkalemia. When using general anesthetics, the inhibitory effect of panangin on the nervous system increases. Succinyl chloride, decamethonium, atracuronium, suxamethonium enhance neuromuscular blockade . The use of enveloping and astringent medications reduces the absorption of potassium and magnesium in the digestive tract. In combination with insulin, dextrose as part of a polarizing mixture, the heart rate is normalized in case of an overdose of cardiac glycosides, in case of ectopic arrhythmias. Panangin improves tolerability cardiac glycosides , is pharmaceutically compatible with their solutions.

Terms of sale

Does not require a prescription.

Storage conditions

Keep out of the reach of children at a temperature of 15-30 degrees Celsius.

Best before date

No more than 5 years.

Panangin's analogs

Level 4 ATX code matches:

Alcohol compatibility

The drug is poorly compatible with alcohol, if only because the medicine is usually used for problems with the heart and vascular system, and alcohol in these cases should be excluded. However, that's not all. If these substances are used simultaneously, vasospasm may occur.

Reviews about Panangin

Reviews about Panangin on the forums are mostly positive. Buyers note the drug as really effective, the medicine makes the heart work easier, eliminates cramps, and really helps. Marked as a good pill for the heart.

Reviews of Panangin during pregnancy are as follows: the medication is often prescribed by doctors and is quite effective, despite the fact that the description of the drug recommends using the drug with caution during this period.

Panangina price

The price of Panangin in tablets is 130 rubles, the price in ampoules is 160 rubles.

How much do tablets cost in St. Petersburg? You can buy them for 125 rubles.

The price of Panangin is 120 and 130 UAH in Ukraine for tablets and solution, respectively.

• Online pharmacies in Russia Russia
• Online pharmacies in Ukraine Ukraine
• Online pharmacies in Kazakhstan Kazakhstan

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Many human diseases are caused by disturbances in the body's metabolic processes. As a result, there is a lack of various vitamins and microelements necessary for the normal functioning of internal organs and systems. The instructions for use of Panangin indicate that the drug is intended to restore potassium and magnesium deficiency and improve the functioning of the cardiovascular system in case of a particular pathology.

Description of the drug

The medicine Panangin is produced in two dosage forms. The tablets are round, biconvex, film-coated, white or grayish in color, without a noticeable odor. The drug in this release form is intended for oral use. Tablets of 50 pieces are produced in jars or blisters placed in cardboard packaging.

The injection solution is available in ampoules, has a white or slightly greenish tint, transparent, without visible chemical and mechanical additives. The solution is packaged in 5 ampoules in a cardboard box, one ampoule – 10 ml.

International name (INN) Potassium aspartate + Magnesium aspartate.

Pharmacological group - a medicine that replenishes the deficiency of magnesium and potassium in the body.

Compound

Panangin contains potassium aspartate (tablet - 158 mg, ampoule - 45 mg), magnesium aspartate (tablet - 140 mg, ampoule - 40 mg) and auxiliary components.

Action of the medicine

The drug Panangin is used in medical practice as a source of magnesium and potassium ions and serves as a catalyst for the body's metabolic processes.

Potassium is necessary for humans for the normal functioning of myocardial fibers and the conduction system of the heart. With a deficiency of this component, the generation and conduction of impulses slows down, which negatively affects the activity of the heart muscle.

Magnesium takes part in the formation of more than three hundred enzymatic cellular systems. They play an important role in the formation of organic compounds and providing the body with energy.

An imbalance in the body of magnesium and potassium ions leads to the development of various diseases. These include hypertensive and ischemic heart disease, arrhythmias, heart rhythm disturbances, atherosclerosis and other pathologies. Panangin is used for these disorders to restore the functioning of the heart and prevent dangerous complications, in particular heart failure.

Pharmacokinetics

After taking the drug orally or using it as an injection, Panangin is quickly absorbed and enters the bloodstream. There is currently no accurate information on the rate of absorption of potassium and magnesium by the body. The drug is excreted by the kidneys.

The drug is quickly absorbed, providing a therapeutic effect

Indications for use

In what area is the medicine used and what does Panangin help with? The drug is used to treat diseases of the heart and blood vessels caused by a lack of potassium and magnesium ions.

Indications for use of Panangin:

• complex treatment of pathologies of the cardiovascular system;
• period of acute myocardial infarction;
• hypertensive heart disease;
• in the presence of pathological conduction pathways of the heart located in the ventricles;
• as a treatment for arrhythmias caused by taking cardiac glycosides and some other medications.

Important! Sometimes tablets are prescribed to patients with insufficient intake of magnesium and potassium from food. In this case, injections are not used.

Medicine dosage

The described drug is prescribed to patients after diagnosis. Let's look at how to take Panangin in various forms of release.

Many patients are interested in what is the best way to take Panangin - before or after meals? Experts recommend taking the tablets after meals, washing down the drug with plenty of water.

Injections

In the form of injections, the drug is administered through a dropper, very slowly (no more than 20 drops per minute), the procedure is performed exclusively by a medical professional. To prepare the solution, combine 20 ml of the product and 100 ml of glucose 5%. A second injection is given if necessary after 5–6 hours.

Tablets and injections are used as an auxiliary or independent therapy for various heart diseases. Self-administration of the drug is extremely dangerous to health. The medicine must be prescribed by a doctor.

Panangin solution is used to install IVs

Contraindications

Panangin and the instructions for use for it indicate the presence of contraindications for both tablets and injections.

Contraindications for oral use:

• acute or chronic kidney failure;
• excess potassium or magnesium in the body;
• chronic adrenal insufficiency;
• violation of the metabolism of amino acids in the body;
• myasthenia gravis with severe course;
• conditions accompanied by dehydration of the body;
• acidosis.

For bradycardia, the drug is prescribed with extreme caution. When diagnosing a decrease in heart rate, taking the drug is prohibited.

Contraindications to the use of injections, in addition to those described above, are as follows:

• the patient's age is under 18 years;
• pregnancy;
• breastfeeding period;
• individual intolerance to the active and auxiliary components of the drug.

Important! Failure to comply with the contraindications of the drug leads to the development of hyperkalemia, hypermagnesemia and other undesirable consequences.

Side effects

If the dosage is violated, disruptions in the functioning of the digestive system, epigastric pain, changes in stool, gastric bleeding, nausea, and dry mouth are observed.

For the heart, Panangin can also cause side effects. Some patients are diagnosed with low blood pressure, heart rhythm disturbances, and atrioventricular block.

From the central nervous system, convulsions, paresthesia, and impaired reflexes are noted. Read in detail about the side effects and contraindications of the drug.

Abdominal pain is one of the side effects of Panangin

Less commonly, difficulty breathing, fainting, changes in cardiogram parameters, and cardiac arrest occur. If a severe overdose develops, it is necessary to urgently transport the patient to a hospital, where resuscitation therapy is carried out with the administration of dextrose or sodium chloride. In especially severe cases, hemodialysis is necessary.

Panangin during pregnancy

Is it possible to use the described drug during pregnancy and breastfeeding? There is no direct prohibition on prescribing the drug. The negative effect of potassium and magnesium on a child has not been confirmed. Despite this, the medicine should be used with caution during pregnancy, especially in the first 4 weeks.

During pregnancy, Panangin should be prescribed exclusively by an experienced doctor only after laboratory confirmation of potassium and magnesium deficiency in the woman’s body. Excess ions can be extremely dangerous for mother and baby, sometimes causing death.

Prescription in pediatrics

Panangin is prescribed to children only if there are serious indications for the use of the medicine, preferably in the form of an injection. To set up a dropper, 10 ml of the product is diluted with 100 ml of glucose (5%).

When using tablets, the dosage of the drug is selected by the attending physician depending on the weight and age of the patient.

Important! According to medical statistics, the use of the drug among newborns helps to close some congenital heart defects.

Panangin or Cardiomagnyl

Many patients are interested in what is better - Panangin or Cardiomagnyl and is it possible to combine these two drugs? It is not recommended to take Panangin and Cardiomagnyl together, because both drugs have a similar composition. Medicines include magnesium, so taking them together may cause excess magnesium in the body. To choose the appropriate remedy for a particular patient, you should consult a specialist and undergo an examination.

Drug compatibility

It is undesirable to simultaneously use the described drug with heparin-type drugs, angiotensin-converting enzyme inhibitors, NSAIDs, potassium-sparing diuretics, and cyclosporine.

It is not recommended to simultaneously use Panangin with heparin, ACE inhibitors, non-steroidal anti-inflammatory drugs, potassium-sparing diuretics, cyclosporine and some other drugs, as this causes the risk of developing an excess of magnesium and potassium ions in the body.

It is important to consider the interaction of Panangin with other drugs

Magnesium in the product reduces the effect of Streptomycin, tetracycline drugs, Polymyxin B and Neomecin.

When Panangin is combined with anesthetics, their negative effect on the human nervous system increases.

Alcohol compatibility

The compatibility of Panangin and alcohol is extremely undesirable. Alcohol itself has a negative effect on the body, and when combined with medications it can cause serious consequences. In this case, the following complications are noted:

• spasm of arteries and veins;
• respiratory dysfunction;
• acute deficiency of electrolytes potassium and magnesium.

Some patients experience cardiac arrest. Given these consequences, Panangin and alcohol should never be combined.

Analogues of the product

In the RLS drug directory you can find the following analogues of Panangin:

• Plus vitamin B6 Panangin is a drug used as a dietary supplement when there is a lack of potassium, magnesium, and vitamin B in the body;
• Aspirin Cardio - used for the treatment and prevention of coronary heart disease, angina pectoris, in the period after heart surgery, after myocardial infarction;
• Riboxin is a complex drug that is prescribed to patients for the treatment of coronary artery disease, heart defects, arrhythmias of various origins, atherosclerosis and other heart diseases. Riboxin contains inosine, which has a positive effect on the functioning of the heart muscle, helps to establish metabolic processes, causes the necessary relaxation of the heart, and normalizes the frequency of contractions of the organ;
• Neocardil - has indications such as neurocirculatory dystonia, coronary heart disease, arterial hypertension, arrhythmias, angina pectoris and other diseases of the cardiovascular system.

It is strictly not recommended to take drugs that are similar in composition and action at the same time; this can only be done as prescribed by a doctor.

Conditions of storage and sale

Panangin in the form of a solution is dispensed from the pharmacy with a doctor's prescription. The tablets are approved as an over-the-counter product. Store the drug in a cool room at a temperature not exceeding 25 degrees.

The product should be stored according to the instructions for use.

What experts say

Stanislav Nikolaevich, cardiologist:
“Many patients believe that Panangin is ordinary vitamins that can be taken without fear for their health. Actually this is not true. Improper use of the medication can lead to severe metabolic disorders and disruption of the heart. I recommend using the product only with a doctor’s prescription in accordance with the instructions.”

Anastasia Mikhailovna, cardiologist:
“Panangin is a good remedy for restoring the deficiency of potassium and magnesium ions in the body. The medicine acts quickly, due to which the therapeutic effect occurs within a short period of time. In addition, Panangin is used to reduce the side effects of some other drugs and prevent various heart complications. I always recommend the drug to my patients.”