Codex Teva - contraindications. Drugs with similar effects

Coldrin, Rinza, Rinicold.

Composition and release form

Chlorphenamine maleate + phenylephrine hydrochloride + paracetamol + caffeine. Caplets (2 mg + 10 mg + 300 mg + 30 mg); tablets (2 mg + 10 mg + 500 mg + 30 mg).

pharmachologic effect

A combined drug, the effect of which is determined by the properties of the components included in its composition. Paracetamol has antipyretic, analgesic and mild anti-inflammatory effects. Chlorphenamine is a histamine H1 receptor blocker and has an antiallergic effect.

Reduces vascular permeability, eliminates swelling and hyperemia of the nasal mucosa, suppresses symptoms allergic rhinitis, making breathing easier. Phenylephrine has a vasoconstrictor effect, reduces the severity of local exudative manifestations, helps eliminate nasal congestion and reduce nasal discharge. reduces feelings of fatigue and drowsiness, improves mental and physical performance, prevents the development of dizziness associated with antihistamine effect drug.

Indications

Symptomatic treatment colds accompanied by rhinitis, nasal congestion, headache, fever, chills, pain in joints and muscles; flu

Application

Caplets. Adults are prescribed 1 caplet every 4 hours with meals; children 6-12 years old - 1 caplet 3 times a day. Tablets are prescribed for adults - 1-2 tablets every 4-6 hours. Maximum daily dose- 8 tab. Children over 6 years old - 1 tablet every 4-6 hours, but no more than 4 times a day for no more than 5 days.

The drug should be prescribed with caution to patients with, patients with elevated IOP, thyrotoxicosis, cardiovascular diseases, patients with epilepsy, as well as elderly and debilitated patients.

Prescription of the drug is possible no earlier than 10 days after the end of treatment with MAO inhibitors. Patients should be warned to refrain from activities that require increased attention while taking the drug.

Side effect

From the central nervous system: dizziness, sleep disturbances, increased excitability and irritability (especially in children), headache.
On PS: nausea, discomfort in the epigastric region, dry mouth. AR.
Other: palpitations, facial flushing, blurred vision.

Contraindications

Prostatic hypertrophy, pyloroduodenal stenosis, gallbladder neck obstruction, simultaneous use MAO inhibitors, beta-blockers, simultaneous administration other drugs containing active substances included in the drug, periods of pregnancy and lactation, childhood up to 6 years old, increased sensitivity to the components of the drug.

The drug should be prescribed with caution in case of glucose-6-phosphate dehydrogenase deficiency, blood diseases, kidney and/or liver failure, angle-closure glaucoma, Gilbert's syndrome, hypertension, diseases thyroid gland, SD, BA.

Overdose

Symptoms are mainly due to the action of paracetamol: pallor may occur skin, anorexia, nausea, vomiting, hepatonecrosis, increased activity of liver transaminases, increased prothrombin time.

Treatment.
Gastric lavage followed by administration activated carbon, symptomatic therapy.

Interaction with other drugs

The drug enhances the effect sedatives, ethanol. Concomitant use with antidepressants, antiparkinsonian drugs, antipsychotics, phenothiazine derivatives ( ,

The cold is one of the most frequent illnesses in adults and children. Its sources are, as a rule, numerous viruses, as well as some bacteria. Although in some studies the proportion viral colds was about one third. Contrary to popular belief, hypothermia does not cause a cold on its own. However, it often occurs precisely during epidemics of colds and therefore often coincides with the moment of infection. More than half of those sick recover without complications, but taking cold and cough remedies helps cope with its unpleasant manifestations.

Viruses, causing colds enter the human body airborne droplet And contact paths. In the first case, the virus is transmitted through tiny droplets that a sick person releases when coughing or sneezing and which are inhaled by a healthy person. In the second, these droplets settle on the surface of surrounding objects, and the virus enters the body healthy person through hands after contact with door handles, hygiene products (towels), etc., on which they were left by a person with a cold. At the very beginning, a cold makes itself known nonspecific symptoms: weakness, fatigue, headache or chills. This period is called prodromal. This is where many acute problems begin. infectious diseases. And at this stage, it is quite difficult to determine by sensation where exactly the infection has settled.

Monto AS. Epidemiology of viral respiratory infections. Am J Med. 2002;112 (Suppl 6A):4S–12S.

Saroea H.G. Common colds. Causes, potential cures, and treatment.Can Fam Physician.1993;39:2215-6

Silva RC, Mendes Gda S, Rojas MA, et al. Frequency of viral etiology in symptomatic adults upper respiratory tract infections. Braz J Infect Dis. 2015;19(1):30–5.

Eccles R. Acute cooling of the body surface and the common cold. Rhinology. 2002;40(3):109–14.

Mitra A, Hannay D, Kapur A, et al. The natural history of acute upper respiratory tract infections in children. Prime Health Care Res Dev. 2011;12(4):329–34.

L'Huillier AG, Tapparel C, Turin L, et al. Survival of rhinoviruses on human fingers. Clin Microbiol Infect. 2015;21(4):381-5.

After the prodrome comes the stage specific manifestations diseases at the site of infection: nasal discharge and sneezing with a runny nose, sore throat and sore throat with pharyngitis or inflammation of the tonsils (tonsillitis, sore throat), hoarseness with laryngitis (inflammation of the larynx) and cough (with all of the above, as well as with tracheobronchitis ). At these stages and for about one week after the disease, the human body cannot fight the cold infection in a targeted manner and tries to respond to it with all the power of its defensive reactions. That's why many unpleasant manifestations Colds are not a consequence of the action of the causative agent of the disease (virus or bacteria) on the human body, but of the body’s protective actions against an invading infection.

The body's nonspecific defense against infection leads to fever, chills, weakness, fatigue and nasal congestion. About a week after contact with the microbe, causing infection, the body begins to secrete specific substances against it, which lead to targeted destruction of the pathogen. Such substances are called antibodies. They are able to almost accurately recognize the causative agent of a particular disease (virus or bacteria) and help the body neutralize it. As a result of this targeted attack, the initial symptoms of the cold disappear and the patient recovers. If the production of antibodies continues after recovery, the person receives immunity against this cold pathogen in the future.

The TEVA company presents drugs for colds, which include Yox®-Teva, which, among other things, is indicated for infectious and inflammatory diseases of the pharynx, including tonsillopharyngitis, tonsillitis and tonsillitis.*

Levinson WE. 7. Pathogenesis. In: Levinson WE. Review of medical microbiology and immunology. 12th ed. McGraw Hill Professional; 2012.

A runny nose can also manifest as a cough if mucus from the nose drips into the throat and irritates the cough receptors there.

Barclay WS, et al. The time course of the humoral immune response to rhinovirus infection. Epidemiol Infect.1989;103(3):659–69.

*For more information, see the instructions for medical use drug These recommendations do not replace consultation with a specialist

Name:

Coldex leva

Pharmachologic effect:

A combined drug, the effect of which is determined by the properties of the components included in its composition. Paracetamol has antipyretic, analgesic (pain reliever) and mild anti-inflammatory effects. Chlorphenamine - a hi-receptor blocker - has an antiallergic effect, reduces runny nose, sneezing, itching and watery eyes associated with increased histamine levels. Chlorphenamine also has M-anticholinergic activity. Mezaton and ephedrine have a vasoconstrictor effect and help relieve nasal congestion. Caffeine prevents the development of dizziness associated with the antihistamine effect of the drug.

Indications for use:

Symptomatic (aimed at improving the patient’s well-being without significantly affecting the cause of the disease) treatment of colds and flu.

Method of application:

Adults are prescribed 1 capsule every 4 hours with meals, children 6-12 years old - 1 capsule 3 times a day. The elixir should be taken before bed. Adults are prescribed 30 ml (1 measuring cup), children over 12 years old - 15 ml (1/2 measuring cup).

Adverse events:

Dizziness, a feeling of discomfort in the epigastric region (the area of ​​the abdomen located directly below the point where the costal arches and the sternum meet), blurred vision, palpitations, and flushing (redness) of the face may occur. When taking capsules, increased excitability and irritability (especially in children, which is associated with the presence of caffeine in the drug).

Contraindications:

Heavy arterial hypertension(steady rise blood pressure), severe forms coronary disease heart, bronchial asthma in the acute stage, angle-closure glaucoma (increased intraocular pressure), hypertrophy (increase in volume) of the prostate gland, obstructive conditions (blockage) gastrointestinal tract And urinary tract, simultaneous use of MAO inhibitors, hypersensitivity to the components of the drug, pregnancy, breastfeeding. The drug in the form of capsules is not prescribed to children under 6 years of age, and in the form of an elixir - up to 12 years of age.

The drug should be prescribed with caution to patients with bronchial asthma, patients with increased intraocular pressure, thyrotoxicosis (thyroid disease), cardiovascular diseases, diabetes mellitus, patients with epilepsy, as well as elderly and weakened patients. Prescription of the drug Koddex Teva is possible no earlier than 10 days after the end of treatment with MAO inhibitors. Patients should be warned about the possibility of dizziness and the need to refrain from potential activities. dangerous species activities while taking the drug.

Release form of the drug:

Capsules in packs of 20 pieces, elixir in bottles of 150 ml. Composition of 1 capsule: chlorphenamine - 0.002 g, mesatone -0.01 g, paracetamol - 0.3 g, caffeine - 0.03 g. 30 ml of elixir contain: chlorphenamine - 0.001 g, paracetamol 0.6 g, dextromethorphan hydrobromide -0 .01 g, ephedrine sulfate - 0.008 g.

Storage conditions:

In a dry, dark place.

Drugs with similar effects:

Kofol (ointment) (Kofol) Kofol (lozenges) (Kofol) Humer 050 (Humer) Humer 150 / Humer monodose (Humer) Combigripp (syrup) (Combigripp)

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Name: Coldex leva

Pharmacological effects:
A combined drug, the effect of which is determined by the properties of the components included in its composition. Paracetamol has an antipyretic, analgesic (pain reliever) and mild anti-inflammatory effect. Chlorphenamine - a hi-receptor blocker - has an antiallergic effect, reduces runny nose, sneezing, itching and watery eyes associated with increased histamine levels. Chlorphenamine also has M-anticholinergic activity. Mezaton and ephedrine have a vasoconstrictor effect and help relieve nasal congestion. Caffeine prevents the development of dizziness associated with the antihistamine effect of the drug.

Coldex Teva - indications for use:

Symptomatic (aimed at improving the patient’s well-being without significantly affecting the cause of the disease) treatment of colds and flu.

Codex Teva - method of application:

Adults are prescribed 1 capsule every 4 hours with meals; children 6-12 years old - 1 capsule 3 times a day. The elixir should be taken before bedtime. Adults are prescribed 30 ml (1 measuring cup); children over 12 years old - 15 ml (1/2 measuring cup).

Coldex Teva - side effects:

Dizziness, a feeling of discomfort in the epigastric region (the area of ​​the abdomen located directly below the convergence of the costal arches and sternum), blurred vision are possible; palpitations, hyperemia (redness) of the face. When taking capsules, increased excitability and irritability (especially in children, which is associated with the presence of caffeine in the medicine).

Codex Teva - contraindications:

Severe arterial hypertension (persistent rise in blood pressure), severe forms of coronary heart disease, bronchial asthma in the acute stage, closed-angle glaucoma (increased intraocular pressure), hypertrophy (increase in volume) of the prostate gland, obstructive conditions (blockage) of the gastrointestinal tract and urinary tract ; simultaneous use MAO inhibitors, hypersensitivity to the components of the drug, pregnancy, breastfeeding. The drug in capsule form is not prescribed to children under 6 years of age, and in the form of an elixir - up to 12 years of age.
The drug should be prescribed with caution to patients with bronchial asthma, patients with increased intraocular pressure, thyrotoxicosis (thyroid disease), cardiovascular diseases, diabetes mellitus, patients with epilepsy, as well as elderly and debilitated patients. The prescription of the drug Codex Teva is likely no earlier than 10 days after the end of treatment with MAO inhibitors. Patients should be warned about the possibility of dizziness and the need to refrain from engaging in potentially hazardous activities while taking the medicine.

Coldex Teva - release form:

Capsules in packs of 20 pieces; elixir in 150 ml bottles. Composition of 1 capsule: chlorphenamine - 0.002 g, mesatone -0.01 g, paracetamol - 0.3 g, caffeine - 0.03 g. 30 ml of elixir contain: chlorphenamine - 0.001 g, paracetamol 0.6 g, dextromethorphan hydrobromide -0 .01 g, ephedrine sulfate - 0.008 g.

Codex Teva - storage conditions:

In a dry place, protected from light.

Important!
Before using the medicine Coldex Teva you should consult your doctor. This instruction is intended for informational purposes only.

A combined drug, the effect of which is determined by the properties of the components included in its composition. Paracetamol has an antipyretic, analgesic (pain reliever) and mild anti-inflammatory effect. Chlorphenamine - a hi-receptor blocker - has an antiallergic effect, reduces runny nose, sneezing, itching and watery eyes associated with increased histamine levels. Chlorphenamine also has M-anticholinergic activity. Mezaton and ephedrine have a vasoconstrictor effect and help relieve nasal congestion. Caffeine prevents the development of dizziness associated with the antihistamine effect of the drug.

Indications for use:

Symptomatic (aimed at improving the patient’s well-being without significantly affecting the cause of the disease) treatment of colds and flu.

Mode of application:

Adults are prescribed 1 capsule every 4 hours with meals; children 6-12 years old - 1 capsule 3 times a day. The elixir should be taken before bed. Adults are prescribed 30 ml (1 measuring cup); children over 12 years old - 15 ml (1/2 measuring cup).

Side effects:

Dizziness, a feeling of discomfort in the epigastric region (the area of ​​the abdomen located directly below the convergence of the costal arches and sternum), blurred vision are possible; palpitations, hyperemia (redness) of the face. When taking capsules, increased excitability and irritability (especially in children, which is associated with the presence of caffeine in the drug).

Contraindications:

Severe arterial hypertension (persistent rise in blood pressure), severe forms of coronary heart disease, bronchial asthma in the acute stage, closed-angle glaucoma (increased intraocular pressure), hypertrophy (increase in volume) of the prostate gland, obstructive conditions (blockage) of the gastrointestinal tract and urinary tract ; simultaneous use of MAO inhibitors, hypersensitivity to the components of the drug, pregnancy, breastfeeding. The drug in the form of capsules is not prescribed to children under 6 years of age, and in the form of an elixir - up to 12 years of age. The drug should be prescribed with caution to patients with bronchial asthma, patients with increased intraocular pressure, thyrotoxicosis (thyroid disease), cardiovascular diseases, diabetes mellitus, patients with epilepsy, as well as elderly and debilitated patients. Prescription of the drug Koddex Teva is possible no earlier than 10 days after the end of treatment with MAO inhibitors. Patients should be warned about the possibility of dizziness and the need to refrain from engaging in potentially hazardous activities while taking the drug.

Release form:

Capsules in packs of 20 pieces; elixir in 150 ml bottles. Composition of 1 capsule: chlorphenamine - 0.002 g, mesatone -0.01 g, paracetamol - 0.3 g, caffeine - 0.03 g. 30 ml of elixir contain: chlorphenamine - 0.001 g, paracetamol 0.6 g, dextromethorphan hydrobromide -0 .01 g, ephedrine sulfate - 0.008 g.

Storage conditions:

In a dry place, protected from light. Attention! Before using Coldex Teva, you should consult your doctor. This instruction is given in free translation and is intended for informational purposes only. To get more complete information Please refer to the manufacturer's instructions.