What injections and Milgamma tablets help from: instructions for use. The average pricing policy is at the level

Milgamma: instructions for use and reviews

Latin name: Milgamma

ATX code: A11EX

Active substance: pyridoxine + cyanocobalamin + thiamine + lidocaine (pyridoxine + cyanocobalamin + thiamine + lidocaine)

Manufacturer: Worwag Pharma GmbH & Co. KG (Germany)

Description and photo update: 02.05.2018

Milgamma is a drug that contains vitamin complex which has a beneficial effect on the nervous tissue of a person. The solution for intramuscular use contains lidocaine for an analgesic effect. The combination of B vitamins, namely 1, 6 and 12, act against pain syndromes, improve metabolic process organism and are excellent antioxidants and help to accelerate the function of repairing nerve tissues.

Milgamma is produced and produced in tablets in the form of dragees and in the form of an injection. Intramuscular injections are prescribed for the manifestation acute pain and when it is necessary to act immediately in order to momentarily alleviate the fate of the patient.

Indications for the use of milgamma

Usually, milgamma prescribed to patients with symptoms of various types of pathology of the nervous tissues and emerging diseases such as paresis or. With a lack of vitamins B1, 6 and 12. Helps with herpes different kind and with shingles.

Feedback on the effectiveness of milgamma injections

Unfortunately, musculoskeletal problems system And neuralgic diseases- the problem is not uncommon, so users this drug, also a lot. Therefore, there are a lot of reviews from patients who have already taken milgamma as a dragee or as an injection.

According to the reviews, you can judge the difference in reception tablets and intramuscular injections. Firstly, the injection is very painful, but it helps much faster than taking the dragee. Many describe their allergic reactions and other side effects that disappear after the end of the course of taking this drug. Despite some inconvenience, people continue to use milgamma to alleviate their condition and maintain normal physical shape.

All reviews are 100% guarantee the fact that a course of medication will help to quickly remove unwanted symptoms of neurological diseases, save a person from herpes and other stressful phenomena. However, it should be remembered that milgamma is a remedy that relieves a disease, but not from its cause. So, if the same symptoms reappear, do not complain that the drug did not help you. For elimination main reason pain, reconsider your life schedule. First of all, physical activity.

side effects of milgamma

There are also contraindications to drug. Before using any kind of milgamma, you need to make sure that the patient does not have an individual intolerance to one of the obsessed vitamins of the complex. The drug is not desirable for people with problems with the heart muscle, as well as for pregnant women and nursing mothers. It is forbidden to use the drug for newborns, especially for children who were born prematurely.

Side effects from taking milgamma appear in the form allergic rash, increased sweating, dizziness, arrhythmia or observed. Side effects are especially pronounced if milgamma is administered abruptly or the dosage of the drug is not observed.

Without a doctor's prescription milgamma application is not recommended. Since the remedy has an extensive and serious effect on the body as a whole. Without the prescribed dosage and schedule for use, the consequences can be more than ridiculous.

Milgamma and alcohol

Extremely dangerous to use milgamma combined with alcohol. Heightened emotionality in a state of intoxication can cause a sharp surge of emotions that lead to unconsciousness a person no longer responsible for their actions. There is also a lot of pressure on the heart and liver.

Cheaper analogues of milgamma

There are two analogues of milgamma on the market - neuromultivit and combilipen. The composition of all these drugs is similar - they contain the same vitamins. If combilipen contains the same dosages of vitamins as milgamma, then neuromultivit contains 2 times more vitamin B6 - pyridoxine hydrochloride.

At the same time, neuromultivit is produced in Austria and at a price it turns out to be even more expensive than the German milgamma. Reliable research that overpaying will achieve more best results- no, so if you have a choice - do not overpay! Moreover, milgamma is the first and original drug.

Combilipen, which is produced by the domestic Pharmstandard, is quite another matter. It will cost you 3-3.5 times cheaper than milgamma, both when buying in injections and when buying in ampoules. The composition of the preparations is similar. The pharmaceutical standard drug is registered in the proper way, so its production is controlled in the same way as the production of other drugs. Therefore, if you do not have prejudices, then you can save money - there is nothing wrong with that.

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Vitamin B complex

Active ingredients

Lidocaine- a local anesthetic that causes all types of local anesthesia: terminal, infiltration, conduction.

Pharmacokinetics

After the / m introduction thiamine is rapidly absorbed from the injection site and enters the blood (484 ng / ml after 15 minutes on the first day of administration at a dose of 50 mg) and is distributed unevenly in the body - with its content in leukocytes 15%, erythrocytes 75% and plasma 10%. Due to the lack of significant reserves of the vitamin in the body, it must be ingested daily. Thiamine crosses the BBB and the placental barrier and is found in breast milk. Thiamine is excreted in the urine in the α-phase after 0.15 hours, in the β-phase - after 1 hour and in the terminal phase - within 2 days. The main metabolites are: thiaminecarboxylic acid, pyramine and some unknown metabolites. Of all the vitamins, thiamine is stored in the body in the smallest quantities. The body of an adult contains about 30 mg of thiamine in the form of 80% thiamine pyrophosphate, 10% thiamine triphosphate, and the rest as thiamine monophosphate.

After IM injection pyridoxine it is quickly absorbed into the bloodstream and distributed in the body, acting as a coenzyme after phosphorylation of the CH 2 OH group in the 5th position. About 80% of the vitamin binds to plasma proteins. Pyridoxine is distributed throughout the body, crosses the placental barrier, is found in breast milk, is deposited in the liver and oxidized to 4-pyridoxine acid, which is excreted in the urine, a maximum of 2-5 hours after absorption. The human body contains 40-150 mg of vitamin B 6 , its daily elimination rate is about 1.7-3.6 mg with a replenishment rate of 2.2-2.4%.

Indications

As a pathogenic symptomatic remedy as part of the complex therapy of diseases and syndromes of the nervous system of various origins:

- neuralgia, neuritis;

- paresis of the facial nerve;

- retrobulbar neuritis;

- ganglionitis (including shingles);

- plexopathy;

- neuropathy, polyneuropathy (diabetic, alcoholic and others);

- nocturnal muscle cramps, especially in older people age groups;

- neurological manifestations of osteochondrosis of the spine: radiculopathy, lumboischalgia, muscular-tonic syndromes.

Contraindications

- pregnancy;

- the period of breastfeeding;

- childhood;

- decompensated heart failure;

- increased individual sensitivity to the components of the drug.

Dosage

Injections are performed deep in / m.

In cases of severe pain syndrome, to quickly achieve high level of the drug in the blood, it is advisable to start treatment with 2 ml daily for 5-10 days. In the future, after the pain syndrome subsides and in mild forms of the disease, they switch either to therapy with an oral dosage form (for example, drug), or to more rare injections (2-3 times a week for 2-3 weeks) with the possible continuation of drug therapy oral form (for example, Milgamma compositum).

The transition to therapy with an oral dosage form (for example, Milgamma compositum) is recommended to be carried out as soon as possible.

Side effects

The frequency of adverse events adverse reactions according to the WHO classification: very common (more than 1 in 10 treated), common (less than 1 in 10, but more than 1 in 100 treated), infrequent (less than 1 in 100, but more than 1 in 1,000 treated), rarely (less than 1 in 1,000, but more than 1 in 10,000 treated), very rare (less than 1 in 10,000, including individual cases), in some cases - symptoms appear with unknown frequency.

From the side immune system: rarely - allergic reactions (skin rash, shortness of breath, anaphylactic shock, Quincke's edema).

From the nervous system: in some cases - dizziness, confusion.

From the side of cardio-vascular system: very rarely - tachycardia; in some cases - bradycardia, arrhythmia.

From the gastrointestinal tract: in some cases - vomiting.

From the skin and subcutaneous tissues: very rarely - increased sweating, acne, itching, urticaria.

From the side musculoskeletal system: in some cases - convulsions.

General disorders and disorders at the injection site: in some cases, irritation may occur at the injection site; systemic reactions are possible with rapid administration or overdose.

If any of the side effects indicated in the instructions are aggravated or any other side effects not indicated in the instructions are noted, the patient should inform the doctor about this.

Overdose

Treatment of overdose consists in drug withdrawal and symptomatic therapy.

drug interaction

Thiamine completely decomposes in solutions containing sulfites, as a result, the decomposition products of thiamine inactivate the action of other vitamins.

Thiamine is incompatible with oxidizing and reducing compounds, incl. iodides, carbonates, acetates, tannic acid, ammonium iron citrate, phenobarbital, riboflavin, benzylpenicillin, dextrose, disulfitamin and others.

Copper accelerates the destruction of thiamine; in addition, thiamine loses its effectiveness with increasing pH values ​​(more than 3).

Therapeutic doses of pyridoxine weaken the effect of levodopa (the antiparkinsonian effect of levodopa is reduced) when taken simultaneously. Interaction with cycloserine, penicillamine, isoniazid is also observed.

With parenteral use of lidocaine in the case of additional use norepinephrine and epinephrine may increase the side effects on the heart. Interaction with sulfonamides is also observed.

Cyanocobalamin is incompatible with salts of heavy metals. Riboflavin also has a destructive effect, especially when exposed to light simultaneously; nicotinamide accelerates photolysis, while antioxidants have an inhibitory effect.

Terms of dispensing from pharmacies

Released by prescription.

Terms and conditions of storage

The drug should be stored in a place protected from light, out of the reach of children at a temperature of 2 ° to 8 ° C; do not freeze. Shelf life - 3 years. Do not use after the expiration date.

Milgamma medicine (shots) is a complex of neurotropic vitamins belonging to group B. In therapeutic doses, this vitamin complex is used in the treatment of diseases of the nervous system, nervous tissues, which entail processes of impaired conduction of nerve impulses or degenerative and inflammatory phenomena.

Pharmacological group

Preparations: vitamin B1 in combination with vitamin B6 and vitamin B12.

The drug Milgamma (injections), composition

pharmachologic effect

Milgamma (injections) is a drug with neuroprotective, analgesic and metabolic effects. Vitamins of group B, which are part of the drug, have an effective therapeutic effect for inflammatory and degenerative diseases nerves and locomotor system. The main purpose of Milgamma injections is injections for nervousness.

Thiamine (vitamin B1) and pyridoxine (vitamin B6) have a positive effect on the nervous and neuromuscular systems. Cyanocobalamin (vitamin B12) is responsible for the synthesis of the myelin sheath, reduces pain associated with damage to the peripheral nervous system. Vitamin B12 promotes the formation of nucleic acids, is responsible for the biosynthesis of protective sheaths of nerve endings and fibers, and affects blood clotting. Another component of the Milgamma injection is the local anesthetic lidocaine.

Milgamma injections: indications for use

When prescribing Milgamma injections, the indications for treatment may be different, but basically it is the treatment of diseases of the nervous system of various origins:

• neuralgia;
• neuritis;
• neuropathy;
• neurological manifestations of osteochondrosis (cervical and lumbar);
• paresis of the facial nerve;
• retrobulbar neuritis;
• ganglionites;
• polyneuropathy (diabetic and alcoholic);
• nocturnal muscle cramps (especially in older age groups);
• radiculitis.

The above diseases are far from all the pathologies that Milgamma helps to cure. From what injections containing vitamins of group B help, you can find out from specialized neuropathologists. Doctors are of the opinion that the drug is effective in systemic neurological diseases, which are caused by a lack of vitamins B1, B6, B12 in the patient's body.

Milgamma preparation (shots): dosage, method of application

To relieve acute pain, one injection (2 ml) is administered intramuscularly for 5-10 days. In the future, after the acute pain syndrome subsides and in mild forms of the disease, they switch to more rare injections (2-3 times a week for 2-3 weeks) with the possible continuation of therapy - the use of Milgamma tablets.

Milgamma drug (injections): contraindications for use

The drug is contraindicated in individual hypersensitivity to the components of the vitamin complex, with heart failure.

In addition, each of the components has its own contraindications.

• Vitamin B1. - contraindicated in those suffering from allergic reactions.
• Vitamin B6 is contraindicated in patients suffering from peptic ulcer stomach and duodenum.
• Vitamin B12 is contraindicated in erythrocytosis, thromboembolism, erythremia.
• Lidocaine is contraindicated in patients with hypersensitivity to lidocaine or other anesthetics.

Side effects

Doctors are often asked the question: are side effects possible when using Milgamma injections? Milgamma injections can really cause allergic reactions. In some cases, there may be increased sweating, tachycardia, acne appears. Reactions are described skin in the form of itching, urticaria. Treatment of itching after Milgamma injections is not separately considered in medicine. After the end of the course of treatment, this unpleasant side effect, as a rule, disappears after the end of the course of taking the medication. In some cases, there may be phenomena of hypersensitivity to the drug, for example, rash, shortness of breath, anaphylactic shock. Also, side effects can occur during too rapid administration of the drug.

Milgamma (shots): side effects in case of overdose

With an overdose of Milgamma, the symptoms of side effects of the drug increase. Treatment of an overdose is to stop taking the drug and conduct symptomatic therapy.

Release form

Milgamma injection solution of a characteristic red color, is available in ampoules (2 ml), in the original factory packaging (25 pcs.).

Storage conditions

Store at a temperature not exceeding 15 ° C, protected from light and out of the reach of children.

Milgamma: instructions, injections, price, patient reviews

Reviews of doctors and patients when evaluating the effectiveness of the vitamin preparation Milgamma are almost always unambiguous: the drug is well tolerated, quickly relieves pain, and when undergoing treatment under the supervision of specialists, it brings long-term positive result. Instructions for use are available to both specialized specialists and people who do not have specific knowledge. In addition, Milgamma is widely used in complex treatment other diseases. What is important, the price of the drug is quite affordable, which makes it possible to use the vitamin complex for people with different financial capabilities.

Very often, patients ask the same question before starting to use Milgamma: is the injection painful? Yes, indeed, Milgamma is a sick prick. But it is worth thinking about the instant effect of relief from pain, which is achieved due to the rapid entry into the blood of the composition of this drug. After all, the patient almost immediately gets rid of discomfort and, with regular use, will forget about the ailment that tormented him for a long time. But for those patients who are still worried about the question - is Milgamma a painful injection or not - it is worth remembering that the composition of the Milgamma injection includes a strong analgesic lidocaine, which has a local anesthetic effect.

All answers to emerging questions - how much does Milgamma cost in injections, what is vitamin preparation Milgamma (shots), what are the benefits and harms of the Milgamma vitamin complex - can be obtained by contacting experienced general practitioners and neuropathologists. Do not forget that each human body unique and demanding individual approach to solve any problem.

The best specialists of the leading clinic of the capital - the Yusupov Hospital will help patients gain confidence in the result of diagnosis and treatment various diseases, provide effective rehabilitation and long-term outcome of treatment. By contacting by phone, you can get advice on your questions and make an appointment with profile specialist.

Bibliography

• ICD-10 (International Classification of Diseases)
• Yusupov hospital
• Badalyan L. O. Neuropathology. - M.: Enlightenment, 1982. - S.307-308.
• Bogolyubov, Medical rehabilitation (manual, in 3 volumes). // Moscow - Perm. - 1998.
• Popov S. N. Physical rehabilitation. 2005. - P.608.

Service prices *

*The information on the site is for informational purposes only. All materials and prices posted on the site are not public offer determined by the provisions of Art. 437 of the Civil Code of the Russian Federation. For exact information, please contact the clinic staff or visit our clinic. The list of paid services provided is indicated in the price list of the Yusupov hospital.

*The information on the site is for informational purposes only. All materials and prices posted on the site are not a public offer, determined by the provisions of Art. 437 of the Civil Code of the Russian Federation. For exact information, please contact the clinic staff or visit our clinic.

Milgamma - complex drug based on B vitamins (thiamine, cyanocobalamin and pyridoxine), which has a beneficial effect on the condition nervous tissue and organs of the musculoskeletal system. In addition, in elevated concentrations the drug is able to have an analgesic effect, improve blood microcirculation and normalize the processes of blood formation.

According to research results, the drug acts as an antioxidant, breaks down fat cells, takes an active part in the synthesis of mediators, in particular, dopamine, as well as adrenaline, noradrenaline, histamine.

What do Milgamma injections help with? How do they combine with other medicines? Isn't it better to replace them with pills? Instructions for use, price, reviews, analogues of Milgamma will be described in the article below.

The composition of the drug depends on the form of release

The composition of Milgamma vitamins in solution is as follows:

• thiamine hydrochloride - 100 mg;
• pyridoxine hydrochloride - 100 mg;
• cyanocobalamin - 1000 mcg;
• lidocaine hydrochloride;
• sodium hydroxide;
• benzyl alcohol;
• sodium polyphosphate.

The composition of the tablets is somewhat different from the composition of the ampoule.

Each pill contains:

• 100 mg of vitamin B1;
• 100 mg of vitamin B6;
• row excipients, including microcrystalline cellulose, talc, povidone, glycerides and more.

Which is better: pills or injections? Based on the characteristics of the composition of the drug, it is safe to say that in ampoule forms it is wider than in Milgamma tablets, and therefore better. The advisability of prescribing a dragee or solution can only be judged by a doctor, given individual characteristics the patient's body, indications for the use of the drug, vitamin tolerance, and the like.

Who is shown a vitamin remedy?

Why is Milgamma prescribed?
Among the indications for the use of the drug Milgamma should be highlighted:

• neuralgic disorders associated with a deficiency of B vitamins;
• decrease in the supporting functions of the body;
• polyneuropathy of alcoholic and diabetic origin;
• paresis of the facial nerve;
• muscle pain;
• shingles with severe pain syndrome;
• radicular syndrome.

You may be interested to know which injections will help with back and lower back pain. Read the details

According to the instructions for use of Milgamma, intramuscular injections the drug is prescribed mainly with the development of neurological symptoms, while tablets are indicated for patients suffering from a deficiency in the body of vitamin B1 and B6.

Milgamma is also useful for hair and skin. It is often recommended to be taken by cosmetologists for people who have problems of this nature. Milgamma is able to quickly restore hair follicles, potentiate the growth of rods and strengthen the hair, preventing its splitting and breaking off.

Milgamma and its analogues in tablets are often used in sports to eliminate the symptoms of muscle strain, myalgia, and also for the general strengthening of the body of athletes.

Mode of application

Tablets are recommended to be taken orally after meals three times a day for a month. Elimination acute manifestations underlying ailment, the doctor may decide on the need to transfer the patient to single dose dosage form. The drug should be taken with a sufficient amount of water.

The solution for injection contains lidocaine, so a skin test must be performed before using it. During treatment severe forms neurological ailments, the drug is prescribed at a dose of 2 ml (1 ampoule) daily. It does not matter when it is better to inject Milgamma, in the morning or in the evening, the main thing is to do it every 24 hours. By subsidence acute symptoms pathological process the patient is transferred to maintenance therapy with the use of medicinal product 2-3 times a week.

It is important to remember that the dosage of the drug should not exceed the maximum allowable norms. Otherwise, the patient may experience side effects and worsen general state health. Therefore, questions such as how often you can inject the drug intramuscularly, what is better Milgamma or Milgamma compositum, what disease Milgamma compositum tablets help against, it is always better to discuss with your doctor.

You will learn detailed instructions for using the drug from the video:

Side effects and contraindications

The annotation to the drug describes in detail what side effects he possesses and in what cases it is better to refuse his reception.

As a result of numerous studies, it was possible to confirm that the tablet forms of the drug in rare cases can provoke:

• appearance skin rash, itching;
• disorders from the digestive sphere;
• shock states.

The manufacturer warns that Milgamma in solution in isolated cases can cause allergic skin reactions, and can also cause acne, dyspepsia, disorders heart rate, convulsions.

Contraindications to the use of the drug are:

• hypersensitivity to the components of the drug;
• frequent allergic reactions in history;
• peptic ulcer of the stomach and duodenum;
• acute violations of cardiac rhythm and conduction in the heart;
• chronic heart failure at the stage of decompensation;
• thromboembolism;
• increase in the number of erythrocytes in the blood.

Interaction

Answering the question of Milgamma's compatibility with alcohol and others medicines, doctors strongly discourage patients from experimenting on their health by combining different variants reception chemical substances. The fact is that the drug, together with ethyl alcohol capable of causing development pathological conditions, which are based on complex variants of impaired functioning of the liver and heart. In addition, Milgamma and alcohol, when used together, strongly excite nervous system and exacerbate underlying ailments.

With what in the complex can you inject the drug so that such actions do not harm the body? Experts don't mind simultaneous reception Movalis, and Milgamma. These preparations perfectly complement each other and provide in the complex a stable therapeutic effect. The compatibility of Milgamma and Diclofenac has also been proven, therefore, these drugs are often prescribed together for the treatment of neurological pathologies, radiculopathy, and radicular syndrome.

Analogues

The drug has great amount substitutes. Some analogues of Milgamma are cheaper than the main vitamin preparation, others may have a higher cost.

In our country, the most popular analogues are Kombilipen, Neuromultivit, Neurobion and Vitagamma.

Kombilipen

Which is better: Milgamma or Combilipen? Kombilipen is one of the most famous domestic analogues Milgamma in ampoules. It contains B vitamins and lidocaine. What is the difference between Milgamma and Kombilipen? Unlike Milgamma, the drug has half the concentration active substances. It is forbidden to be taken by pregnant women and mothers who are breastfeeding babies. The only one positive moment- Kombilipen costs much cheaper than a well-known foreign analogue.

Vitagamma

Another analogue of Milgamma in injections is Vitagamma. This medication is very similar in composition, principle of action and contraindications for use to its relative, so patients often wonder how much it costs. Since the drug is produced in Russia, the price of Vitagamma is significantly lower than the cost foreign analogues and is approximately 150 rubles. for 10 ampoules.

Neuromultivitis

Which is better: Neuromultivit or Milgamma? Complex B-vitamin preparation of Austrian origin, Neuromultivit has proven itself well in the domestic pharmaceutical market. It is well tolerated by the human body and in rare cases provokes the development of adverse reactions. It is recommended to use it for severe pain caused by diseases of the nervous tissue, since Neuromultivit contains higher concentrations of vitamins than other multivitamin preparations.

What pills will help to remove pain syndrome for diseases of the musculoskeletal system, read

Neurobion

Neurobion is a vitamin preparation that is available in the form of tablets and injections. The composition of the drug is 100 mg of thiamine disulfide, 200 mg of pyridoxine hydrochloride, 240 mg of cyanocobalamin. Which is better: Neurobion or Milgamma? It is difficult to judge this, since both drugs are quite effective. Therefore, in each specific clinical case you should listen to the recommendations of doctors.