Gastal instructions for the use of tablets for adults. Influence on the ability to drive vehicles and work with machinery

Perhaps each of us is familiar with uncomfortable sensations in the stomach and intestines. In everyday life, we eat the wrong foods, our diet is completely unbalanced, and it often happens that we choose fast food as a snack. All this affects the state gastrointestinal tract. Apart from malnutrition, affect the gastrointestinal tract stressful situations, Lifestyle, bad habits. Many of us with discomfort in the stomach or intestines take Gastal. What helps this pharmacological agent?

Gastal refers to pharmacological group medicines antacid type. The composition of this pharmaceutical preparation includes substances that have a beneficial effect on the gastric mucosa, in particular:

  • magnesium aluminum carbonate gel;
  • magnesium hydroxide;
  • additional substances.

When Gastal tablets enter the body due to active substances, hydrochloric acid in the stomach binds, thereby eliminating discomfort and normalizing natural digestive processes. As practice shows, most often Gastal is taken by people who experience pain in the stomach area after taking fatty or spicy food, as well as for heartburn and after excessive drinking to eliminate toxins.

By binding free hydrochloric acid in the gastric cavity, Gastal helps to normalize the alkaline-acid balance, which allows you to get rid of painful and uncomfortable sensations. Often such a drug is taken by people who adhere to a dietary diet. If you are on a diet to get rid of excess weight, but by chance you had a breakdown and ate 1-2 cakes, then there is nothing to worry about - you can take a Gastala tablet, which will allow you to digest the incoming food faster.

Indications for use Gastal

As already mentioned, Gastal has a very good effect on the stomach, binding free hydrochloric acid. The pharmacological agent begins to act almost immediately after it enters the digestive tract. The effect of the antacid type lasts an average of 2 hours. Due to its active substances, Gastal inhibits the production of a number of enzymes, in particular, lysolecithin and pepsin, and also minimizes the effect of bile acid on the mucous membrane of the esophagus and stomach. According to the instructions, Gastal is recommended to be taken in such cases:

  • with gastritis of the hyperacid type;
  • in case of detection ulcer pathologies stomach or duodenum;
  • with diaphragmatic hernia;
  • in case of belching or heartburn;
  • with acute pancreatitis;
  • in case of development of cholecystitis;
  • with the development of erosive processes in the esophagus;
  • with vagrant dyspepsia;
  • in case of food or other poisoning;
  • with a disease of gastroesophageal reflux pathology;
  • in the case of the syndrome of delayed excretion of the contents of the stomach.

As already mentioned, Gastal helps well with heartburn, as well as with alcohol intoxication. If in the morning a person experiences hangover syndrome, then with this pharmacological preparation you can get rid of toxins faster.

How to take Gastal?

Gastal can be purchased at any pharmacy. This pharmaceutical preparation is available in the form of tablets. The dosage form of Gastal is the same, the difference is flavor additive and the number of tablets in the package. On pharmacy shelves you can find packages with the number of tablets 12, 24, 30 and 48 pieces. The most common Gastal tablets do not have palatability and covered with the usual shell. But manufacturers also offer cherry and mint flavored tablets. Most often, these pharmacological agents are purchased for children.

Before purchasing and taking Gastal, consult with your healthcare professional, as this drug has a number of contraindications, and its excessive or improper use can lead to side effects. Pay attention to the expiration date and release date. Gastal should be stored in a cool, protected from children and direct contact. sun rays place. You should also observe the established temperature threshold for storing the drug. The course of treatment cannot exceed 14 days, since Gastal is taken exclusively for therapeutic purposes.

It is recommended to take the medicine one hour after a meal or one hour before a night's sleep. In any case, before starting a treatment course, it is best to consult a gastroenterologist. Adults are allowed to take 2 tablets no more than 3 times a day. children age category from 6 to 12 years are allowed to take no more than 1 tablet three times a day. Treating experts do not advise giving this drug to children under the age of six. It is not necessary to drink liquid or swallow a tablet. Her pharmacological form provides absorption. The tablet should be placed on the cheek or under the tongue: within a few minutes, the active substances will begin to be absorbed into the mucous membrane and, together with the saliva produced, will enter the esophagus and stomach.

If gravity and discomfort in the gastrointestinal tract due to overeating or use alcoholic beverages, then you can take one tablet of Gastal. As practice shows, a person experiences relief after a few minutes.

Contraindications to taking Gastal

If you carefully read the instructions for this pharmacological agent Please refer to the list of contraindications. So, Gastal is strictly forbidden to use in such cases:

  • with the progression of Alzheimer's disease;
  • in case of individual intolerance to individual components, in particular lactose;
  • in case of kidney failure, with a severe pathology;
  • with the manifestation of an allergic reaction to the constituent components and active substances.

Gastroenterologists advise not to take such a drug to people in old age, as well as women during the period of gestation. In practice, there have been cases when taking Gastal caused diarrhea, constipation, nausea and a change in taste perception.

Side effects

Taking the pharmacological drug Gastal can also provoke the development of side effects. As a rule, they can manifest themselves with the wrong dosage or overuse tablets. Treating professionals and leading pharmacists identify the following side effects drug:

  • nausea;
  • manifestation of allergic reactions in various forms;
  • development of osteoporosis;
  • diarrhea
  • encephalopathy;
  • constipation;
  • violation of the normal functioning of the kidneys;
  • osteomalacia;
  • nephrocalcinosis;
  • hypercalciuria.

If Gastal is taken by people suffering from renal insufficiency, then as side effects they may experience an increase in the level blood pressure and constant thirst. In this case, you should immediately contact your treating specialist and undergo a full-scale study in order to prescribe a full and balanced treatment course.

With an overdose of Gastal, the above side effects may occur. It is better not to take Gastal with other medicines at the same time. The interval between taking different pharmaceuticals must be at least 2 hours.

Gastal copes very well with various diseases GIT. Range pharmacological action this drug is quite wide. Don't get busy self-treatment. Only a specialist can prescribe a correct, balanced and effective treatment course.

Registration number: P N014448/01
Tradename: Gastal®
INN or grouping name: -
Dosage form: lozenges
Compound
1 tablet contains: active substances: aluminum hydroxide - magnesium carbonate gel 450.0 mg, magnesium hydroxide 300.0 mg; Excipients: mannitol (E421) 120.00 mg, sorbitol (E420) 50.00 mg, lactose monohydrate 30.00 mg, corn starch 75.80 mg, sodium cycpamate 7.00 mg, sodium saccharinate 0.20 mg, talc 28, 00 mg, magnesium stearate 6.00 mg, peppermint flavor 3.00 mg.
Description:
Round tablets from white to cream color with a smooth surface and a chamfer.
Pharmacological group: antacid
ATC Code: A02AX

Pharmacological properties

Pharmacodynamics
Gastal® is a combined antacid that reduces hyperacidity gastric juice and has no stimulating effect on the secretion of gastric juice.
Aluminum hydroxide-magnesium carbonate gel and magnesium hydroxide provide immediate (immediately after ingestion) and long-term (about 2 hours) neutralization of gastric hydrochloric acid, while maintaining acidity in the stomach at a physiological level (pH 3-5). One tablet of Gastal® neutralizes 21.5 mmol of hydrochloric acid.
The drug Gastal® inhibits the action of pepsin, lysolecithin and bile acids, eliminates dyspeptic symptoms. Enhances protective and regenerative processes in the gastric mucosa. Aluminum ions have a cytoprotective effect by increasing the secretion of mucin and sodium bicarbonate, activating prostaglandin E2 and NO, accumulating epidermal growth factor at the site of mucosal injury, and increasing the concentration of phospholipids in the walls of the stomach.
Pharmacokinetics
The drug Gastal® does not have a systemic effect in patients with normal function kidneys. After interacting with hydrochloric acid gastric juice, aluminum hydroxide reacts with phosphates and carbonates to alkaline environment intestines and is excreted in the feces in the form of insoluble salts. Magnesium hydroxide reacts with hydrochloric acid in gastric juice to form magnesium chloride, which has osmotic properties and a mild laxative effect, which neutralizes the fixative effect of aluminum hydroxide in small intestine. Magnesium ions are excreted in the feces as insoluble carbonate.

Indications for use

Heartburn, dyspeptic symptoms (after taking medications, alcohol, coffee, dietary errors, smoking); conditions accompanied by increased acid formation: peptic ulcer of the stomach and duodenum, gastritis; reflux esophagitis; hernia esophageal opening diaphragm.

Contraindications

Hypersensitivity to aluminum, magnesium salts or other components of the drug; severe renal failure; Alzheimer's disease; hypophosphatemia; lactose intolerance, lactase deficiency or glucose-galactose malabsorption; childhood up to 6 years old.

Carefully

In chronic renal failure (CRF), pregnancy and during breastfeeding, adults and children over 12 years old weighing less than 50 kg, children from 6 to 12 years old, the elderly.

Use during pregnancy and during breastfeeding

The drug Gastal® is not excreted from breast milk. When used during pregnancy and during breastfeeding, it is necessary to evaluate the ratio of benefit to the mother and risk to the fetus and infant.

Dosage and administration

Inside, gradually dissolving in the mouth.

1-2 tablets 4-6 times a day approximately 1 hour after meals and at bedtime, but not more than 8 tablets per day. The duration of admission is not more than 2 weeks.
Similar doses are recommended for treating heartburn with or without food.
Adults and children over 12 years old weighing less than 50 kg, children aged 6 to 12 years
The dose is half the recommended dose for adults and children over 12 years of age weighing at least 50 kg. The duration of admission is not more than 2 weeks.

Dose adjustment is not required. The duration of admission is not more than 2 weeks.

Overdose

Symptoms of acute overdose are not described.
At long-term use high doses of drugs containing aluminum and magnesium may develop hypophosphatemia, hypocalcemia, hypercalciuria, osteomalacia, osteoporosis, hypermagnesemia, hyperaluminemia, encephalopathy, nephrocalcinosis and impaired renal function. Perhaps the development of more pronounced adverse reactions from the gastrointestinal tract (GIT) (constipation, diarrhea), in patients with renal insufficiency - thirst, lowering blood pressure, hyporeflexia.
Treatment: symptomatic therapy.

Side effect

Interaction with other drugs

The drug Gastal® for simultaneous application enhances the activity of levodopa and nalidixic acid, reduces and slows down the absorption of quinolones, isoniazid, naproxen, iron preparations, indomethacin, chlorpromazine, beta-blockers, diflunisal, H2-histamine receptor blockers, fat soluble vitamins, indirect anticoagulants, barbiturates.
When interacting with metal ions that are part of antacids, tetracyclines form insoluble chelate complexes; as a result of this interaction, the absorption of tetracyclines is reduced by more than 90%. Simultaneous reception these drugs is not possible. If concomitant use is necessary, tetracycline should be taken at least 2 hours before taking an antacid.
In the presence of aluminum and magnesium hydroxides contained in the antacid, the absorption of ciprofloxacin and ofloxacin is reduced by 50-90%.
In the presence of antacids, the bioavailability of captopril is significantly reduced, and the combined use of antacids and metoprolol leads to a decrease in the concentration of metoprolol in the blood plasma.
The simultaneous use of high doses of antacids can reduce the absorption of ranitidine by 10-33%.
The use of antacids does not affect the bioavailability of amoxicillin, cephalexin and the combination of amoxicillin and clavulanic acid, but can significantly reduce the absorption of doxycycline from the gastrointestinal tract.
An increase in urine pH during antacid therapy may increase the tubular reabsorption of basic (alkaline) drugs and reduce the reabsorption of acidic compounds. Antacids may reduce and delay the absorption of salicylates, including acetylsalicylic acid, and also, by increasing the pH of the urine, contribute to a more rapid excretion of salicylates in the urine from the body, with a concomitant decrease in their concentration in the blood serum by 30-70%.
The absorption of cardiac glycosides, including digoxin and digitoxin, does not significantly decrease when used simultaneously with antacids.
M-anticholinergics, slowing down the motility of the stomach, increase the duration of the drug Gastal®.
In order to prevent possible interaction the drug Gastal® with other medicines it is recommended to take it 1 hour before or 1 hour after their use.

special instructions

Influence on the ability to drive vehicles and work with machinery

Gastal is a combined antacid drug, which has adsorbing, enveloping and anesthetic properties.

The drug reduces the increased acidity of gastric juice and does not have a stimulating effect on the secretion of gastric juice.

The active ingredients - aluminum hydroxide-magnesium carbonate gel and magnesium hydroxide - provide immediate (immediately after ingestion) and long-term (about 2 hours) neutralization of gastric hydrochloric acid, while maintaining acidity in the stomach at a physiological level (pH 3-5). 1 tablet of Gastal neutralizes about 21.5 mmol of hydrochloric acid.

Gastal inhibits the action of pepsin, lysolecithin and bile acids, eliminates dyspepsia. Enhances protective and regenerative processes in the gastric mucosa.

Aluminum ions have a cytoprotective effect by increasing the secretion of mucin and sodium bicarbonate, activating prostaglandin E2 and NO, accumulating epidermal growth factor at the site of mucosal injury, and increasing the concentration of phospholipids in the stomach wall.

The drug is available in the form of lozenges. One tablet contains aluminum hydroxide-magnesium carbonate gel - 450 mg and magnesium hydroxide - 300 mg.

Indications for use

What helps Gastal? According to the instructions, the drug is prescribed in the following cases:

  • with gastritis with high acidity,
  • with ulcers of the stomach and small intestine,
  • heartburn,
  • erosions of the gastric mucosa,
  • reflux esophagitis,
  • diaphragmatic hernia,
  • acute pancreatitis,
  • for prevention peptic ulcer,
  • with dyspepsia with long delay food in the stomach.

Instructions for use Gastal, dosage

Tablets are taken orally, gradually dissolving in the mouth.

Adults and children over 12 years old with a body weight of at least 50 kg are prescribed 1-2 tablets. 4-6 times a day. Reception is recommended 60 minutes after a meal and before bedtime. Maximum daily dose- no more than 8 tablets. Duration of therapy - no more than 14 days.

A similar regimen is indicated for the treatment of heartburn. The tablets are taken with or without food.

Adults and children over 12 years of age with a body weight of less than 50 kg, as well as children of 6-12 years old, are prescribed half of the recommended dose for adults with a body weight of 50 kg or more. Duration of therapy - no more than 14 days.

Patients with chronic renal failure - dose adjustment is not required. The duration of admission is not more than 2 weeks.

Side effects

The instruction warns of the possibility of developing the following side effects when prescribing Gastal:

Contraindications

Gastal is contraindicated in the following cases:

  • increased individual sensitivity to any of the components of the drug;
  • lactase deficiency or glucose-galactose malabsorption;
  • reduced levels of phosphate in the blood;
  • Alzheimer's disease.

Overdose

Symptoms of acute overdose are not described. With prolonged use of high doses of drugs containing aluminum and magnesium, hypophosphatemia, hypocalcemia, hypercalciuria, osteomalacia, osteoporosis, hypermagnesemia, hyperaluminemia, encephalopathy, nephrocalcinosis and impaired renal function may develop.

Perhaps the development of more pronounced adverse reactions from the gastrointestinal tract (GIT) (constipation, diarrhea), in patients with renal insufficiency - thirst, lowering blood pressure, hyporeflexia.

Symptomatic therapy is used.

Analogues Gastal, price in pharmacies

If necessary, you can replace Gastal with an analogue according to active substance and therapeutic effect are the drugs:

  1. Altacid,
  2. Alumag,
  3. Rennie.

When choosing analogues, it is important to understand that the instructions for the use of Gastal, the price and reviews of drugs of similar action do not apply. It is important to consult a doctor and not to make an independent replacement of the drug.

Price in Russian pharmacies: Gastal lozenges 12 pcs. - from 138 to 163 rubles, according to 481 pharmacies.

Store in a dry place at an air temperature not exceeding 25°C for up to 3 years.

In this medical article you can get acquainted with the drug Gastal. The instructions for use will explain in which cases you can take pills, what the medicine helps with, what are the indications for use, contraindications and side effects. The annotation presents the form of release of the drug and its composition.

In the article, doctors and consumers can only leave real reviews about Gastal, from which you can find out whether the medicine helped in the treatment of heartburn, gastritis and ulcers in adults and children, for which it is also prescribed. The instructions list the analogues of Gastal, the prices of the drug in pharmacies, as well as its use during pregnancy.

Antacid medicine, which is used for gastritis and stomach ulcers, is Gastal. Instructions for use indicate that lozenges well neutralize the hydrochloric acid of gastric juice.

Release form and composition

Gastal is available in the form of lozenges. One tablet contains aluminum hydroxide-magnesium carbonate gel - 450 mg and magnesium hydroxide - 300 mg.

Tablets have a rounded shape, smooth surface and white (cream is allowed) color. They are packaged in a blister of 6 pieces. A cardboard pack contains 2,4,6, 8 or 10 blisters with the appropriate number of tablets and instructions for using the drug.

pharmachologic effect

His active ingredients neutralize hydrochloric acid of gastric juice, reducing its irritating effect on the mucous membrane digestive tract. The resulting insoluble magnesium salts relax the smooth muscles of the intestine and have a mild laxative effect.

Aluminum salts absorb a large number of water, forming an additional protective local anesthetic film on the mucous membrane. Therapeutic action appears immediately after taking the drug. The residence time in the stomach depends on its evacuation activity and ranges from 1 to 2 hours. Gastal is not absorbed into the systemic circulation and does not cause alkalosis.

Indications for use

What helps Gastal? indigestion, heartburn, pain and discomfort in the stomach - this is all that pills are good for.

Clinical indications for the use of Gastal are:

  • diseases characterized by increased acid formation: gastritis, gastric ulcer, reflux esophagitis;
  • dyspepsia, such as epigastric pain, heartburn, discomfort, sour belching after drinking alcohol, coffee, errors in the diet, nicotine, as well as arising after taking a number of drugs.

Instructions for use

Gastal is taken orally. The tablet should be gradually dissolved (not swallowed whole). Adults are recommended to take 1-2 tablets 4-6 times a day 1 hour after meals and at bedtime, but not more than 8 tablets in 24 hours. The duration of administration should not exceed 2 weeks.

For prevention, Gastal is used before the alleged irritating effect on the gastrointestinal mucosa. Similar doses are recommended for heartburn, regardless of food intake. For children aged 6-12 years, half the adult dose is recommended.

Contraindications

Gastal is contraindicated:

  • with hypophosphatemia;
  • children under 6 years old;
  • with chronic renal failure;
  • with Alzheimer's disease;
  • at hypersensitivity to one of the components of the drug.

With caution, you can use the drug for children under the age of 12 years. Gastal during pregnancy and breastfeeding can be taken, but only under the supervision of a doctor. Negative consequences Gastal's use during pregnancy has not been studied.

Side effects

Gastal tablets are well tolerated, with their use in the recommended therapeutic doses, side effects practically do not develop. Rarely, nausea, vomiting, constipation or diarrhea, changes in taste sensations develop.

It is extremely rare that there may be allergic reactions in the form of a rash on the skin, itching or urticaria (a characteristic rash and itching resembling a nettle burn).

Children, during pregnancy and lactation

As with the appointment of all other drugs, the use of Gastal during pregnancy is possible only in special occasions and only on the recommendation of a doctor. Use with caution in children under 12 years of age.

special instructions

For long-term treatment Gastal requires serious testimony. Adults weighing less than 50 kg and children under 12 years of age may require reduced doses and a shorter treatment period.

drug interaction

There is a weakening of absorption from the gastrointestinal tract of drugs taken simultaneously with Gastal. Therefore, between taking various medicines, you need to take a break.

Gastal's analogs

  1. Akrepat Forte (suspension).
  2. Almagel (suspension).

The group of antacids includes analogues:

  1. Magnatol.
  2. Talcid.
  3. Tannacomp.
  4. Flax seeds.
  5. Becarbon.
  6. Andrews Liver Salt.
  7. gastracid.
  8. Gasterin.
  9. Magnistad.
  10. Topalkan.
  11. Rutacid.
  12. Scoralite.
  13. magnesium oxide.
  14. Rivolox.
  15. Alumag.
  16. Roquel.
  17. Tams.
  18. calcium carbonate.
  19. Gelusil.
  20. Daigin.
  21. Gelusil.
  22. Andrews antacid.
  23. Gastric.
  24. Almol.
  25. Gastroromazole.
  26. Almagel.
  27. Agiflux.
  28. Alugastrin.
  29. Relzer.
  30. Tisacid.
  31. Gaviscon forte.
  32. Gelusil varnish.
  33. Maalox mini.
  34. Antarite.
  35. Alfogel.
  36. sodium bicarbonate.
  37. Gestid.
  38. Rennie.
  39. Aktal.
  40. RioFast.
  41. Almagel Neo.
  42. Phosphalugel.
  43. Magalfil 800.
  44. sodium bicarbonate.
  45. Anacid forte.

Holiday conditions and price

The average cost of Gastal (tablets No. 12) in Moscow is 167 rubles. Implemented without a prescription.

The shelf life of Gastal tablets is - years from the date of their release. It is necessary to store the drug in a dark, dry place at an air temperature not higher than +25 C. Keep away from children.

Gastal- a combined antacid that reduces the increased acidity of gastric juice and does not have a stimulating effect on the secretion of gastric juice.

The drug Gastal inhibits the action of pepsin, lysolecithin and bile acids, eliminates dyspeptic symptoms. Enhances protective and regenerative processes in the gastric mucosa.

Pharmacological properties

Pharmacodynamics. Aluminum hydroxide-magnesium carbonate gel and magnesium hydroxide provide immediate (immediately after ingestion) and long-term (about 2 hours) neutralization of gastric hydrochloric acid, while maintaining acidity in the stomach at a physiological level (pH 3-5). One tablet of Gastal neutralizes 21.5 mmol of hydrochloric acid. Aluminum ions have a cytoprotective effect by increasing the secretion of mucin and sodium bicarbonate, activating prostaglandin E2 and NO, accumulating epidermal growth factor at the site of mucosal injury, and increasing the concentration of phospholipids in the walls of the stomach.

Pharmacokinetics. The drug Gastal does not have a systemic effect in patients with normal renal function. After interaction with hydrochloric acid of gastric juice, aluminum hydroxide reacts with phosphates and carbonates in the alkaline environment of the intestine and is excreted in the feces in the form of insoluble salts. Magnesium hydroxide reacts with hydrochloric acid in gastric juice to form magnesium chloride, which has osmotic properties and a mild laxative effect that neutralizes the fixative effect of aluminum hydroxide in the small intestine. Magnesium ions are excreted in the feces as insoluble carbonate.

Indications for use Gastal

Dyspeptic phenomena (after taking medicines, alcohol, coffee, dietary errors, smoking); conditions accompanied by increased acid formation: peptic ulcer of the stomach and duodenum, gastritis; reflux esophagitis; hiatal hernia.

Dosage and administration

Inside, gradually dissolving in the mouth. Adults and children over 12 years of age weighing at least 50 kg 1-2 tablets 4-6 times a day approximately 1 hour after meals and at bedtime, but not more than 8 tablets per day. The duration of admission is not more than 2 weeks. Similar doses are recommended for treating heartburn with or without food. Adults and children over 12 years old weighing less than 50 kg, children aged 6 to 12 years old - the dose is half the recommended dose for adults and children over 12 years old weighing at least 50 kg. The duration of admission is not more than 2 weeks. Patients with chronic renal failure - dose adjustment is not required. The duration of admission is not more than 2 weeks.

Application features

The recommended doses and duration of treatment should not be exceeded when used in patients with impaired renal function. The use of the drug Gastal does not affect the ability to drive vehicles and control other mechanisms.

Side effects

Interaction with other drugs

The drug Gastal, with simultaneous use, enhances the activity of levodopa and nalidixic acid, reduces and slows down the absorption of quinolones, isoniazid, naproxen, iron preparations, indomethacin, chlorpromazine, beta-blockers, diflunisal, H2-histamine receptor blockers, fat-soluble vitamins, indirect anticoagulants, barbiturates. When interacting with metal ions that are part of antacids, tetracyclines form insoluble chelate complexes; as a result of this interaction, the absorption of tetracyclines is reduced by more than 90%. Simultaneous reception of these drugs is not possible. If concomitant use is necessary, tetracycline should be taken at least 2 hours before taking an antacid.

In the presence of aluminum and magnesium hydroxides contained in the antacid, the absorption of ciprofloxacin and ofloxacin is reduced by 50-90%. In the presence of antacids, the bioavailability of captopril is significantly reduced, and the combined use of antacids and metoprolol leads to a decrease in the concentration of metoprolol in the blood plasma. The simultaneous use of high doses of antacids can reduce the absorption of ranitidine by 10-33%. The use of antacids does not affect the bioavailability of amoxicillin, cephalexin and the combination of amoxicillin and clavulanic acid, but can significantly reduce the absorption of doxycycline from the gastrointestinal tract.

An increase in urine pH during antacid therapy may increase the tubular reabsorption of basic (alkaline) drugs and reduce the reabsorption of acidic compounds. Antacids can reduce and slow down the absorption of salicylates, including acetylsalicylic acid, and also, by increasing the pH of the urine, contribute to a more rapid excretion of salicylates in the urine from the body, with a concomitant decrease in their concentration in the blood serum by 30-70%. The absorption of cardiac glycosides, including digoxin and digitoxin, does not significantly decrease when used simultaneously with antacids. M-anticholinergics, slowing down the motility of the stomach, increase the duration of the drug Gastal®. In order to prevent possible interaction of the drug Gastal® with other drugs, it is recommended to take it 1 hour before or 1 hour after their use.

Contraindications

Hypersensitivity to aluminum, magnesium salts or other components of the drug; severe renal failure; Alzheimer's disease; hypophosphatemia; lactose intolerance, lactase deficiency or glucose-galactose malabsorption; children's age up to 6 years. With caution in chronic renal failure (CRF), pregnancy and during breastfeeding, adults and children over 12 years of age weighing less than 50 kg, children aged 6 to 12 years, old age.

Use during pregnancy and during breastfeeding

The drug Gastal is not excreted in breast milk. When used during pregnancy and during breastfeeding, it is necessary to evaluate the ratio of benefit to the mother and risk to the fetus and infant.

Overdose

Symptoms of acute overdose are not described. With prolonged use of high doses of drugs containing aluminum and magnesium, hypophosphatemia, hypocalcemia, hypercalciuria, osteomalacia, osteoporosis, hypermagnesemia, hyperaluminemia, encephalopathy, nephrocalcinosis and impaired renal function may develop. Perhaps the development of more pronounced adverse reactions from the gastrointestinal tract (GIT) (constipation, diarrhea), in patients with renal insufficiency - thirst, lowering blood pressure, hyporeflexia. Treatment: symptomatic therapy.

Questions and answers on the topic "Gastal"

Question:When and in what dosage should Gastal be administered to patients?

Answer: Gastal should be administered internally when hyperacidity gastric juice, food poisoning and peptic ulcer of the duodenum and stomach, chronic and acute hyperacid gastritis ( inflammatory process in the stomach as a result of a persistent increase in acidity). Due to the fact that this drug has the ability to bind phosphates and delay their absorption from the gastrointestinal tract, there is also its use in elevated content in the blood of phosphates (hyperphosphatemia), accompanying kidney failure. Dosage: Take this drug 4-6 times a day, 1-2 tablets (1 hour after meals). Tablets must be swallowed, not chewed in any case.