How and how much you can take Arcoxia tablets: instructions for use. Arcoxia drug compatibility

Arcoxia is a highly selective COX-2 inhibitor belonging to the group of NSAIDs.

What is the composition and form of release of Arcoxia?

This drug is produced in tablets, they are of three types. Some of them are covered with a green film sheath, biconvex, their shape is apple-shaped, engraved "ARCOXIA 60", and on the other side - "200". They contain 60 mg of the active substance, and it is represented by etoricoxib.

Excipients: magnesium stearate, calcium hydrogen phosphate, croscarmellose sodium, microcrystalline cellulose. The shell consists of carnauba wax and opadra II green 39K11520, as well as lactose monohydrate, triacetin, hypromellose, aluminum varnish based on indigo carmine, titanium dioxide.

The second type of tablets is also white, apple-shaped, on one side embossed "ARCOXIA 90", and on the other - "202". They contain etoricoxib in the amount of 90 mg.

And the third type of tablets is coated with a light green shell, embossed with "ARCOXIA 120", and on the other side there is an engraving - "204". Concerning active component, then its amount is 120 mg.

The drug can be bought at the pharmacy only with a prescription. The tablets are packed in blisters, which are placed in cardboard boxes. The medicine should be stored at a temperature not exceeding 30 degrees. Its implementation period is three years.

What is the pharmacological action of Arcoxia?

The active component of the drug Arcoxia is able to block the formation of prostaglandins, resulting in an anti-inflammatory effect on the body, and the tablets also have an analgesic and antipyretic effect.

What are the indications for Arcoxia?

Arcoxia is indicated for use as symptomatic treatment conditions such as: osteoarthritis, gouty arthritis, rheumatoid arthritis, and it is also used in the presence of ankylosing spondylitis. In addition, it is prescribed in the presence of pain after dental procedures. surgical interventions.

What have Arcoxia contraindications to application?

As for contraindications, Arcoxia has instructions for use, says that they will be as follows, I will list these conditions:

Intolerance acetylsalicylic acid;
Erosive and ulcerative changes in the stomach or duodenum;
Bleeding from the gastrointestinal tract;
Hemophilia;
lactation period;
Aggravation ulcerative colitis;
kidney failure;
Heart failure;
Condition after shunting;
Pregnancy;
Age up to 16 years;
Hypersensitivity to the substances that make up Arcoxia.

Use the drug with caution if the patient has an infection Helicobacter pylori, in old age, diabetes, smoking, hypertension, edema and some other conditions.

What is the use and dosage of Arcoxia?

Arcoxia is taken orally with a small amount of chilled water, and it is recommended to take it after a meal.

With osteoarthritis, the dosage will be 60 mg 1 time per day, it will be considered the maximum daily dose, it is not recommended to exceed it.

For rheumatoid arthritis or a history of ankylosing spondylitis, the dose is 90 mg once daily. In acute gouty arthritis - 120 mg once a day.

The duration of use of Arcoxia at a dose of 120 mg should not exceed eight days. In hepatic insufficiency, the daily dosage should not be increased by more than 60 mg.

Is it possible to overdose from Arcoxia?

With an overdose of Arcoxia, it can be noted negative phenomena from the digestive tract, kidneys and heart. Treatment is symptomatic, if necessary in a hospital.

What have Arcoxia side effects actions?

Laboratory changes: an increase in the level of hepatic transaminases and CPK activity, an increase in nitrogen in the urine, a decrease in hematocrit and hemoglobin, in addition, thrombocytopenia, hyperkalemia, leukopenia, an increase in creatinine and uric acid are noted.

From the side digestive system: belching, epigastric pain, bloating, nausea, diarrhea, flatulence, increased intestinal motility, constipation, gastritis, dryness of the oral mucosa, stomach ulcer, esophagitis, vomiting, hepatitis.

From the nervous system: confusion, headache, sleep disturbance, dizziness, weakness, taste disturbance, sensitivity disturbance in the form of paresthesia, depression, anxiety state much less often hallucinations.

From the urinary system: proteinuria, renal failure, while these conditions are reversible, and disappear when this drug is discontinued.

From the side of the cardiovascular system: palpitations, increased pressure, myocardial infarction, hot flashes, hypertensive crisis, impaired cerebral circulation, heart failure.

Among other side effects can be noted: gastroenteritis, cystitis, urethritis, bronchitis, pharyngitis, as well as arthralgia, myalgia and convulsions. In addition, there are changes in metabolism, in particular, fluid retention occurs, leading to edema; appetite changes, and body weight may also increase.

What are the analogues of Arcoxia?

The analogues of Arcoxia include the drug Etoricoxib, it should be used only after consultation with a competent doctor.

Conclusion

To Diclofenac (text from instructions)⇒ Etoricoxib (found him)

Base Interactions (Diclofenac)

Interactions from trade names (Rapten Rapid)

To relieve inflammation and pain in the arsenal of physicians is a large number of drugs. Instructions for use will tell you about the mechanism of action and the rules for taking Arcoxia. Long-term use of many of them is accompanied by various complications. The greatest preference in rheumatology is given to non-steroidal anti-inflammatory drugs, which have the ability to act selectively.

Arcoxia is a representative latest generation drugs in this group. It is registered for use in drug treatment pathologies of the musculoskeletal system in many countries of the world. Characterized high efficiency at least risk development of adverse effects.

Pharmacological properties

The effectiveness of Arcoxia is due to the main active substance- Etoricoxib. It is a powerful and reliable tool for pain management, incl. chronic, closely associated with the inflammatory process. According to the instructions, it is intended for oral use. Arcoxia satisfies all the criteria for highly effective symptomatic therapy: it gives a quick, stable result, has a convenient dosing regimen, is well tolerated by patients, and does not require additional analgesics.

From which pills are prescribed to patients who suffer from rheumatic diseases for a long time and need systematic anesthesia. The drug Arcoxia has:

• Analgesic action - relieves pain syndrome associated with inflammation or damage to organs and tissues. In terms of the severity of pain reduction and restoration of functionality, the minimum dose of Arcoxia is not inferior to the effect of taking maximum dose Diclofenac, Indomethacin, Naproxen, Ibuprofen, or Celebrex is significantly superior to placebo and Paracetamol. Therapeutic action a drug based on Etoricoxib is noticeable in the shortest possible period of time, while in total it causes complications from the gastrointestinal tract less often, which makes Arcoxia the best drug in the line of painkillers. A tangible beneficial effect is manifested within 28 minutes after application and lasts for a year after the completion of the course of treatment.

• Anti-inflammatory action - suppresses the exudative and proliferative phases, eliminating all signs of inflammation: relieves redness of the skin, feeling hot, swelling of soft tissues, joint enlargement, swelling, soreness, morning stiffness and loss of functionality. The drug demonstrates the most stable decrease in inflammatory activity, against the background of low toxicity, not inferior to therapeutic effect other selective and non-selective NSAIDs.

• Antipyretic effect - reduces high temperature in febrile conditions, reducing the excitability of the heat-regulating centers of the hypothalamus. It has a long antipyretic effect, which is additional - it is not used exclusively for antipyretic therapy. Arcoxia is banned in pediatrics.

Composition, release forms

The drug is manufactured by the pharmaceutical company Merck Sharp and Dome, the country of origin is Spain / the Netherlands, and MSD Pharmaceuticals is engaged in promotion and sale in Russia.

Arcoxia is produced in the only dosage form- Film-coated tablets. There are several types of tablets. All of them are apple-shaped, convex on both sides, the name and dosage of Etoricoxib are engraved on one edge, and 101, 200 or 202 are embossed on the other. They have the same set of components, but differ in the dosage of the main active ingredient, the dye that is part of the film shell and number of tablets per pack:

• 30 mg - blue-green, 28 pcs.;

• 60 mg - dark green, 14, 28 tablets;

• 90 mg - white, 2.7 or 28 pieces;

• 120 mg - yellow-green, 7 or 28 tablets.

The instructions indicate the composition of the auxiliary ingredients of the drug:

• calcium hydrogen orthophosphate, magnesium stearate - fillers, give the desired mass, ensure the release rate and completeness of absorption;

• microcrystalline cellulose, croscarmellose sodium - baking powder, promote rapid dissolution.

How does Arcoxia work?

The therapeutic effect of anti-inflammatory drugs is due to the suppression of the COX-2 enzyme, which is actively formed in response to tissue damage, and is responsible for the synthesis of the most important mediators pain - prostaglandins. These physiologically active substances in a certain concentration are constantly present in almost all organs and tissues. IN excess they contribute to the development and maintenance of the inflammatory process, pain. By suppressing the production of prostaglandins in the lesion, most nonsteroidal drugs inhibit not only the pathological COX-2 enzyme, but also the physiological COX-1, violating normal processes in organism.

How long you can take painkillers, anti-inflammatory medicine - depends on its safety. To avoid negative complications (mainly from the side of the cardiovascular and digestive systems), the task of the drug is to act selectively.

Arcoxia is a highly selective inhibitor, it suppresses the pathological enzyme 106 times more strongly, therefore it is allowed for long-term use. When evaluating the long-term prescription, the special MEDAL program in the course of studies (1.5 years of continuous use) revealed a relatively greater safety of Arcoxia.

The instructions indicate the main parameters of the pharmacokinetics of Arcoxia, ensuring the speed and completeness of the development of the effect:

• easily absorbed into the systemic circulation, bioavailability (ability to be absorbed) - 100%;

• food intake does not have a significant effect on the absorption process, the time to reach the maximum concentration on an empty stomach is 1 hour, when taken with food - 2 hours;

• 92% of the drug passes into the form associated with plasma proteins, penetrates through physiological barriers;

• actively biotransformed in the liver, 1-2% is excreted by urinary tract unchanged;

• half-life - 22 hours, metabolites do not affect COX-1, leave the body mainly with urine, a small part - with feces;

• gender, age, body weight, race indicators do not change, renal, liver failure influence slightly.

Indications for admission

The list of diseases - from which Arcoxia helps, is indicated in the instructions. It is important to consider that the drug is potent, but is not used to get rid of pain of any etiology, its main purpose is the treatment of rheumatic diseases.

How many days the course of treatment for Arcoxia lasts is decided by the doctor, based on the type, activity of the disease, and individual characteristics.

Numerous studies have established:

• on the 8th day of taking 120 mg / day, Arcoxia completely relieves pain in 90% of patients with gouty arthritis, the pain subsides after 4 hours;

• after 2 days of use, 90 mg significantly reduces pain, improving the quality of life of patients suffering from,. For stable clinical efficacy with osteoarthritis, a 6-week course of 60 mg of the drug or a 12-week course of 30 mg is usually sufficient;

• in dental, gynecological practice, 90 mg of medication is prescribed for pain relief for 3 days, relief comes after 30 minutes;

• for chronic lumbar pain, 60 mg of Arcoxia per day is indicated, for acute pain and during exacerbations no more than 120;

• 120 mg of Arcoxia before surgery is sufficient to reduce pain intensity for 8 hours.

Instructions for use

When appointing Arcoxia, they adhere to the rules of the minimum effective dosage the shortest possible course. The therapeutic effect is achieved faster if you take the pill on an empty stomach, but the completeness of assimilation does not depend on the fact of eating, so taking the pill before or after eating does not really matter.

• swallow the tablets whole, without chewing and with a sufficient amount of liquid;

• with kidney dysfunction, the excretion of metabolic products is difficult, which increases the toxicity of the drug, so the doses in such patients are limited to 30 mg / day or 60 mg / 48 hours;

• with liver dysfunction, metabolism slows down - the maximum allowed dose is 60 mg / 24 hours;

• 120 mg can be taken daily only for 8 days;

• if there is no positive dynamics, you should notify the doctor and replace Arcoxia with another one;

• with long-term therapy, constant monitoring of pressure, cardiac functions is required, every 2 weeks - kidney, liver tests.

There were no cases of overdose in the study. Exceeding the permissible doses may be accompanied by indigestion, the functioning of the renal system, adverse cardiovascular events (pressure surges, arrhythmia, increased heart rate). Treatment of overdose - removal of remnants of tablets from the gastrointestinal tract, supportive therapy. There is a category of patients who are not recommended to use Arcoxia.

The instructions list the following identified contraindications:

• individual hypersensitivity to the component of the drug, the drug as a whole, other NSAIDs;

• tendency to allergic reactions;

• peptic ulcers, bleeding in the gastrointestinal tract;

• severe forms of insufficiency - renal, hepatic, cardiac;

• inflammation of the intestinal mucosa;

• ischemia, hypertension;

• intolerance to lactose, glucose, galactose, elevated level calcium in the blood;

• planning a pregnancy, pregnant, breastfeeding women;

• age 0-16 years old.

Side effects

The safety of Arcoxia directly depends on the daily and total dosage. It has been established that a dose of less than 150 mg for 3 weeks does not suppress the physiological enzyme COX-1, does not destroy the gastric mucosa, does not cause prolonged bleeding, does not affect platelet aggregation.

The instruction warns that in some cases the following side effects may occur:

• dizziness, migraine, distraction or anxiety, sleep problems, depression, taste disorder;

• discomfort in the upper part of the peritoneum, indigestion, defecation process, rapid liquid stool, nausea, heartburn, ulcers, increased peristalsis;

• inflammation of the liver, stomach, intestines, proteinuria, diseases of the genitourinary tract, infections of the respiratory system;

• anaphylaxis, state of shock, a sharp decline pressure, bronchospasm, dyspnea, excess fluid accumulation;

• muscular, joint pain, convulsions, hemorrhages in the skin and mucous membranes, urticaria, allergic dermatitis, itching, Stevens-Johnson syndrome;

• flu-like condition, feeling of pain behind the sternum, conjunctivitis, tinnitus, impaired visual function;

• attacks of heat, chills, heart rhythm disturbances, cerebral circulation, pressure surges;

• increased hepatic transaminases, creatine kinase, changes in the blood picture.

The answer to the question: is it possible to drink alcohol during the treatment of Arcoxia, the same as in the case of other non-steroidal drugs - the combination of analgesics with alcohol turns the drug into a poison that damages the liver and gastrointestinal organs.

The instruction also warns whether to refrain or be careful when performing work that requires concentration and prompt response.

When taking Arcoxia concomitantly with other medications possible drug interactions should be considered:

oral contraceptives - blockage possible blood vessel detached thrombus;

• Digoxin, Rifampicin, lithium - their content in plasma changes.

The opinion of doctors and patients

There are many reviews about Arcoxia - and from medical workers and from patients. Almost all doctors agree that the launch of Arcoxia tablets on the pharmaceutical market has opened a new milestone in rheumatology and orthopedics. This modern drug provides a quick, lasting effect, well anesthetizes, it can be prescribed to elderly patients with chronic joint diseases, incl. caused by the inflammatory process. The doctors' comments are also unanimous in assessing the safety of Arcoxia: it is well tolerated by patients, it acts gently, cases of serious side effects and intolerance are extremely rare. Doctors also respond positively to the convenient form of release with different dosages, which allows you to rationally approach the treatment of this expensive drug.

As civilization develops, human life expectancy increases. Against this background, the number of diseases characteristic of age-related changes in organism. Including, such as arthritis and arthrosis. The development of medicine helps to successfully cope with destructive-dystrophic and related diseases of the joints.

One of effective means in the fight against the manifestations of arthritis and arthrosis, the non-steroidal anti-inflammatory drug Arkosksia becomes. It is valid in case treatment of joint diseases any age. Inflammatory processes affecting the joints can be observed even in childhood and adolescence.

In contact with

What is Arcoxia

With all the wide choice of options for analogues, it is Arcoxia that is recognized as one of the most successful and viable options medicines at inflammatory diseases joints and musculoskeletal system.

instructions for use

The active ingredient is Etoricoxib. belonging to the group of coxibs. in number pharmacological actions includes:

• anti-inflammatory;
• Painkiller;
• Antipyretic.

The main task of the drug is to inhibit the activity of COX-2 by a selective mechanism, which prevents the biosynthesis of prostaglandtins, inflammatory mediators. At the same time, the active substance does not damage the mucous membrane of the digestive tract and does not affect functional activity platelets.

Attention! Available in tablet form. One tablet may contain, depending on the dosage, 30,60,90, 120 mg of active substance.

Variants of drug analogues

The pharmaceutical market offers a wide range of medical preparations for the treatment of joint diseases. Among them are analogues of Arcoxia with a similar principle of operation. They can be recommended in a situation of intolerance to a drug prescribed by a doctor. Another reason for choosing to purchase analogues is the desire to purchase an effective drug at a favorable price.

the drug has analogues

In the pharmacy you can find the following analogues:

• ibuprofen;
• Diclofenac;
• Lidron;
• Ketonal;
• Ostalon and many others.

In total, in a pharmacy, a pharmacist can offer more than 50 drugs that are approximately the same in terms of the principles of action.

It is impossible to choose a drug that is ready to become a replacement for Arcoxia on your own. The appointment of any remedy for the treatment of diseases of the musculoskeletal system, arthritis and arthrosis can only be done by the attending physician.

The Russian industry is currently producing a wide range of drugs, the action of which is similar, and the composition is almost identical.

In this list, Dilaxa occupies one of the leading positions in terms of popularity. The price of packaging of this option varies from 75 to 100 rubles. The package contains three active capsules.

Nise becomes an affordable analogue. Its disadvantages include large quantity possible side effects.

Arcosia and alcohol

The combination of medicines and alcohol is not recommended at all, but there are groups of drugs, the use of which together with alcohol-containing drinks becomes dangerous to health and life. This list includes Arcoxia and alcohol. Their compatibility is not implied even in minimal dosages. The action of the drug lasts 24 hours. Recommended throughout this period avoid alcohol intake.

What can you take medicine for?

What can Arcoxia be used for? The list of diseases is quite wide. Direct indication for prescription becomes:

• Rheumatoid arthritis;
• Inflammation of the joints of various etymologies;
• Gouty arthritis with inflammation and pain;
• Surgical operations in dentistry;
• Osteoarthritis.

take with severe inflammation

Due to the high degree of anti-inflammatory effects, Arcoxia for colds with severe inflammation may be prescribed by the attending physician. A successful prospect of application in case of any inflammation is based on the readiness of the active substance to neutralize the action of cyclooxygenase. Due to this, there is a decrease in the level of formation of archidonic acid. Active substance reduces the level of prostaglandins in inflamed tissues.

Arcoxia or movalis, which is better

Often patients are faced with the suggestion of pharmacists using on par with Arcoxia Movalis.

Such a proposal by a pharmacist in the event, for example, that at a particular moment the assortment of the prescribed medicinal substance, well justified.

From the point of view of physicians, due to the approximately similar composition, the funds are interchangeable and equivalent. Both about belong to the type of non-steroidal anti-inflammatory drugs medicinal means.

The possibility of replacement can only be determined by the attending physician.

Instructions for use

The advantage of using this drug it becomes possible to take it without taking food into account. Available in the form of easy-to-use biconvex tablets taken orally. Wash down the drug need a little water room temperature.

The dosage of Arcoxia tablets is determined by the doctor depending on the diagnosis in which the drug is prescribed:

• In case of treatment rheumatoid arthritis the single dose is 90 mg once a day.
• Up to 120 mg per day is recommended for the treatment of acute gouty arthritis.
• Up to 90 mg per day is used in case of appointment after dental surgery.
• No more than 60 mg per day is taken for osteochondrosis and other diseases if the patient has liver failure.

The tablet should be taken with water

How many days to take the medicine, the therapist or neurologist will determine. In most cases, the duration of use is 8 days. The effectiveness of the use can only be determined by a doctor. It is possible to prolong the use of the drug. Constant use forbidden.

Important! In case of violation of the rules of admission, the patient may experience side effects.

Features of taking the drug for osteochondrosis

The drug is recommended for a wide range inflammatory diseases. It is especially effective for arthritis, arthrosis, inflammation of the musculoskeletal system. Among the diagnoses for which the use

Arcoxia is especially useful, including osteochondrosis. It is advisable to use the cervical version of this disease. The drug contributes to a noticeable improvement in the patient's condition, in short time relieves acute pain syndrome.

Action provides reduction of the inflammatory process.

Arcoxia side effects

in number side effects includes:

• Negative manifestations in respiratory system manifested as shortness of breath, cough, nosebleeds, exceptional cases bronchospasm may occur.
• At negative impact on nervous system possible dizziness, confusion, weakness, taste disturbance, tinnitus. In rare cases, hallucinations, impaired sensitivity can be observed.
• When side effects affect cardiovascular system, an increased heartbeat appears, arterial blood pressure rises blood pressure. Among the rare but noted manifestations, experts call congestive heart failure, atrial fibrillation, hot flashes, cerebrovascular accident.
• Muscle cramps, myalgia, arthralgia may appear.
• Required upon admission measuring the level of protein in the urine, its increase will inform about an overdose or individual intolerance.
• The drug can cause various disorders in the gastrointestinal tract, including gastritis, ulcerative bleeding, belching, vomiting, and bloating.

Others may appear side effects. If you notice a deterioration in well-being while taking the drug, it is recommended to immediately seek advice from your doctor. In the presence of negative manifestations, it is recommended to apply for the appointment of analogues. In particular, in such a situation, inexpensive Russian analogues with affordable prices.

possible side effects

Forbidden use given medicinal product and its analogues during pregnancy and breastfeeding. It is not recommended to prescribe without the presence of vital indications to patients under 18 years of age. Consultation with a specialist is required when prescribing for many chronic diseases. Including with severe liver damage, diseases of the gastrointestinal tract, arterial hypertension, coronary heart disease and others.

Manufacturer

This drug is Russian market company from the Netherlands Merck Sharp and Dome B.V. It was founded in 1668. For the first century and a half, the company was a pharmacy, only in the second half of the 19th century the descendants of the founder began to specialize in the industrial production of medicines. The company is currently headquartered in the United States.

The trademark is a transnational corporation with representative offices in all developed countries, including Russia. In our country, the company's office is located in Moscow. The company has developed a wide range of effective medicines that are intended for the treatment of joints and bones.

Attention! Production is carried out only at the company's factories in compliance with strict quality control requirements.

Video: Arcoxia tablets instructions for use

In conclusion, it is important to pay attention to the possibility of taking only on the direct prescription of the attending physician.

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Arcoxia (Arcoxia) is a drug that is a COX-2 inhibitor, which in therapeutic concentrations helps to block the formation of prostaglandins, relieves inflammation, relieves pain and lowers body temperature.

Arcoxia, whose active ingredient is etoricoxib, belongs to the group of non-steroidal anti-inflammatory drugs (NSAIDs), and is also an antirheumatic drug.

Manufacturer

The drug is produced in the Netherlands by the pharmaceutical company Merck Sharp & Dohme BV.

Description

Composition and form

It is produced in the form of tablets, with the content of the active ingredient 30, 60, 90 and 120 mg. Each tablet is biconvex, apple-shaped and film-coated. Externally, the tablets differ in color and embossed text on the sides.

Ask your question to a neurologist for free

Irina Martynova. Graduated from the Voronezh State medical University them. N.N. Burdenko. Clinical intern and neurologist of BUZ VO "Moscow polyclinic".

Arcoxia 30 tablets are blue in color, with "ACX 30" embossed on one side and "101" embossed on the other. Sold in blisters of 2, 4, 7 or 14 pieces each. 1, 2 or 4 blisters are placed in the secondary carton.

The average price is from 180 rubles.

Arcoxia 60 are green tablets marked "ARCOXIA 60" on one side and "200" on the other side. Sold in aluminum blisters of 7 pieces each. The secondary packaging contains 1 or 4 blisters.

The average price is from 240 rubles.

The drug at a dosage of 90 mg - white tablets marked "ARCOXIA 90" and "202" on the sides, respectively. Produced in aluminum blisters of 7 tablets each. 1 or 4 blisters are placed in the package.

The average price is from 350 rubles.

Light green 120 mg tablets labeled "ARCOXIA 120" and "204". Realization is made in aluminum blisters of 7 tablets each. The secondary packaging contains 1 blister.

The average price is from 615 rubles.

Each secondary carton package contains an additional detailed instructions on the use of Arcoxia.

Dosage

Arcoxia is intended for oral administration. Rendering speed therapeutic effect increases when using the drug in the morning on an empty stomach.

Therapy for ankylosing spondylitis is carried out by taking 60 mg.

In the treatment of gouty arthritis, Arcoxia 120 mg every 24 hours is used.

At severe pain Arcoxia can be used, but only in the acute period.

To relieve the patient of postoperative pain after dental procedures, it is recommended to use the drug Arcoxia in daily dosage 90 mg.

In the absence of positive dynamics within 2-3 days, a consultation with a doctor about a possible replacement of the drug is necessary.

Duration of therapy

The course of treatment in many cases is 7 days. In the treatment of gouty arthritis, the duration of therapy is often 8 days. Dosage of the drug for treatment acute pain is strictly individual and is calculated by the attending physician. The course of treatment for postoperative pain should be no longer than 3 days.

Indications for use

• osteoarthritis;
• ankylosing spondylitis;
• rheumatoid arthritis;
• gouty arthritis;
• inflammation and pain after dental surgery.

Application for hernia of the spine

Arcoxia is widely used for the symptomatic treatment of herniated discs. Providing analgesic and anti-inflammatory effect, the drug Arcoxia improves mobility in the spine, reduces muscle spasms and improvement general condition patient. The recommended dose in the treatment of spinal hernia is 90 mg.

The decision on the advisability of using Arcoxia for intervertebral hernia should only be taken by a specialist.

Contraindications

Arcoxia has the following contraindications:

• individual intolerance to the components of the drug;
• bronchial asthma;
• polyposis of the nose and / or maxillary sinuses;
• erosive and ulcerative lesions of the stomach, duodenum 12;
• bleeding from the gastrointestinal tract;
• inflammatory pathologies of the intestine;
• blood clotting disorders;
• severe insufficiency of kidney function;
• pathology of peripheral arteries;
• hypertension;
• pregnancy and lactation;
• age up to 16 years.

With caution, Arcoxia is used in patients with:

• ulcerative changes in the gastrointestinal tract in history;
• Helicobacter pylori infections;
• previous long-term treatment other NSAIDs;
• alcohol addiction or frequent use ethanol;
• diabetes mellitus;
• smoking;
• puffiness.

special instructions

When taking Arcoxia, mandatory control over blood pressure. During the first 14 days after the start of treatment with the drug, each of the patients requires monitoring of blood pressure.

If, while taking the drug, there is an increase in liver enzymes by more than 2 times, the use of the drug should be discontinued.

Co-administration of Arcoxia and others nonsteroidal drugs anti-inflammatory effects are strictly prohibited.

Patients with lactose intolerance should be very careful when taking the drug due to the content in the shell of a small amount of this substance.

Patients whose activities are related to increased concentration attention, special vigilance is required.

• Renal/liver dysfunction

People with severe kidney failure, as well as with progressive kidney pathologies, taking Arcoxia is contraindicated.

The drug should not be used in patients with severe insufficiency of liver function and with active pathologies of the organ.

• Use in pregnant women

The use of Arcoxia by pregnant women and during breastfeeding contraindicated. The use of tablets may adversely affect the fertility of women, making it undesirable for patients planning to become pregnant.

• Use in children

The pharmacokinetics of the drug in children under 16 years of age has not been studied, so its use is contraindicated.

• Use in elderly patients

There are no restrictions on the use of the drug in elderly patients.

Side effects

Among the frequent and moderate side effects in the treatment of etoricoxib are:

• dry mouth;
• feeling of nausea, vomiting;
• belching;
• epigastric pain;
• stool disorder;
• dyspepsia;
• gas formation, bloating;
• gastritis;
• ulceration of the gastric mucosa or duodenal ulcer;
• ulceration of the oral mucosa;
• headache;
• feeling dizzy;
• violation of taste perception;
• weakness and fatigue;
• feeling of anxiety, fear;
• attention disorder;
• arrhythmia;
• increased blood pressure, hot flashes;
• insufficiency of heart functions;
• myocardial infarction;
• cough;
• respiratory failure;
• nosebleeds;
• allergic reactions;
• appetite disorder;
• puffiness.

To the rare side effects relate:

• gastroenteritis, gastric and duodenal ulcers with perforation and bleeding;
• hepatitis;
• impaired consciousness, visual and auditory hallucinations;
• visual or hearing disorder;
• proteinuria;
• anaphylactic shock;
• hypertensive crisis;
• bronchospasm;
• urticaria, angioedema;
• convulsions, myalgia, arthralgia;
• chest pain.

Overdose

There are no data on drug overdose. If, nevertheless, a significant amount of the drug was taken by the patient, there is a risk of developing adverse reactions from the gastrointestinal tract, kidneys, liver, heart.

Treatment is symptomatic.

Interaction with other drugs

Compatibility with anticoagulants leads to a change in prothrombin time. Simultaneous reception of these funds requires regular monitoring of blood coagulation.

At joint application Arcoxia and diuretics or antihypertensive drugs decrease the effectiveness of the latter. Also, the combination of these agents enhances their nephrotoxic effect.

The use of Arcoxia simultaneously with acetylsalicylic acid is permissible only in low doses (up to 60 mg). Use with drugs, the content of acetylsalicylic acid in which is higher than 60 mg contributes to ulcerative lesion stomach.

Gastric ulceration is also possible when Arcoxia is combined with other non-narcotic analgesics.

When Arcoxia is combined with cyclosporins and tacrolimus, it significantly increases their Negative influence on the patient's kidneys.

The combination of the drug with lithium preparations, estrogens increases their plasma concentration. A slight increase in plasma concentration is also observed with the simultaneous administration of Arcoxia and digoxin.

With the combination of etoricoxib and methotrexate, changes in the pharmacokinetic parameters of the latter occur.

A decrease in plasma concentrations of etoricoxib is observed when combined with rifampicin.

Storage, dispensing from pharmacies

Arcoxia is available by prescription.

It is necessary to store the drug in a dark room at a temperature below 30 degrees. The shelf life is 36 months from the date of manufacture, which is indicated on the secondary packaging.

Interaction with alcohol

The official annotation to the drug indicates the impossibility simultaneous reception Arcoxia and alcohol.

- from 30 rubles;