Sodium thiosulfate: rules of use and contraindications. Sodium thiosulfate for allergies: features of use in conservative and alternative medicine

Chemical substance, which is known as antichlor or sodium hyposulfite - sodium thiosulfate is used in medicine to cure the body with different states. According to numerous reviews, this substance, used externally and intravenously, perfectly fights poisoning, skin diseases, such as psoriasis, is indispensable in gynecology for the treatment of infertility.

What is sodium thiosulfate

A solution of sodium thiosulfate (Natrii thiosulfate) is a crystalline hydrate formed by salts of Na and thiosulfuric acid. This substance is also called sodium sulfate and is widely used in:

• medicine;
• textile industry;
• food, mining industries;
• construction (as an additive to concrete mixtures).

This chemical compound has wide application, but more in demand for treatment various diseases, because it is a substance that:

The sodium salt of thiosulfuric acid has the formula na2s2o3 and consists of the Na salt and thiosulfuric acid. Salt with acid form a crystalline hydrate, which is easily soluble in water. Get it in the following ways:

• oxidation of Na polysulfides;
• dissolving Na sulfide with water;
• boiling excess sulfur with Na sulfate, Na hydroxide;
• anhydrous thiosulfate - by the reaction of sulfur with Na nitrite.

Release form

The drug is available in two dosage forms- powder or solution. The powder is packaged in plastic bags, used externally or taken orally after dilution with water. The solution is released in ampoules, the amount of active substance in which can be 1.5 and 3 grams. The solution is applied intravenously, strictly according to the doctor's prescription. As part of a solution excipient sodium bicarbonate is used.

Instructions for use sodium thiosulfate

According to official instructions sodium thiosulfate is intended for the treatment of:

• neuralgia;
• allergic reactions;
• scabies;
• arthritis
• intoxications (cyanides, arsenic, lead, mercury);
• lupus erythematosus;
• dermatitis.

When applied externally, the drug, getting on the skin, forms sulfur and sulfurous anhydrite. These compounds cause the death of the scabies mite, create conditions for the healing of the skin after burns. Once inside the body, the active substance of the drug binds, removes toxins that provoke allergic reactions, severe intoxication, poisoning.

Indications for use

Good detoxification properties make it possible to use the medicine for cleansing the body, removing toxins and toxins. Many years of application experience this tool for medicinal purposes shows its effectiveness in the treatment of:

• genital tuberculosis;
• gynecological diseases such as infertility (problems with ovulation, ovarian cysts);
• alcohol addiction;
• burns.

Sodium thiosulfate in gynecology for the treatment of other diseases is used in conjunction with other drugs, since it is used to treat ovarian cysts, problems with ovulation complex method, and sodium thiosulfate acts as an anti-inflammatory and detoxifying agent. Both ampoules and powder are dispensed only by prescription.

Dosage

Assign sodium thiosulfate intravenously, externally and orally:

• sterile solution should be taken orally only in dissolved form (10% water solution). Assign to drink 2-3 g at a time;
• intramuscularly - 5-10 ml at a time, in case of cyanide poisoning - 50 ml;
• a sterile solution is applied to the skin for external use; after drying - the skin is moistened with 6 percentage solution of hydrochloric acid.

Side effects

In the official instructions, among the side effects, only an allergy to active substance drug. Appearance allergic reaction on the drug - an extremely rare occurrence, but when not correct dosage, uncontrolled intake severe allergic reactions are possible. In case of cyanide, mercury, arsenic or lead poisoning, the drug is effective if taken soon after the poison enters the body. Risk of occurrence adverse reaction in case of emergency, it is minimal, since the drug is completely non-toxic.

Contraindications

The official instructions for the drug indicate that the contraindications for use are:

• hypersensitivity to active substance drug;
• pregnancy (use is possible only when absolutely necessary);
• breastfeeding period.

The price of sodium thiosulfate

The drug sodium thiosulfate is released more often with a 30% solution. The price for a package containing 10 ampoules is 53-100 rubles (region - Moscow). The cost of the medicine may vary in different pharmacies of the country. You can choose the best price on the websites of pharmacies. In addition to the prices for the drug, in the Internet pages of pharmacies you can find a description of the product, a photo, a breakdown of prices by region, and available analogues.

Forms non-toxic or low-toxic compounds with salts of heavy metals, halogens, cyanides. It has the properties of an antidote in relation to aniline, benzene, iodine, copper, mercury, hydrocyanic acid, sublimate, phenols. In case of poisoning with compounds of arsenic, mercury, lead, non-toxic sulfites are formed. The main mechanism of detoxification in case of poisoning with hydrocyanic acid and its salts is the conversion of cyanide into thiocyanate ion, which is relatively non-toxic, with the participation of the enzyme rhodonase - thiosulfate cyanide-seratransferase (found in many tissues, but shows maximum activity in the liver). The body has the ability to detoxify cyanides, but the rhodonase system works slowly, and in case of cyanide poisoning, its activity is not enough for detoxification. In this case, to accelerate the reaction catalyzed by rhodonase, it is necessary to introduce exogenous sulfur donors, usually sodium thiosulfate, into the body.

Anti-scabies activity is due to the ability to disintegrate into acidic environment with the formation of sulfur and sulfur dioxide, which have a damaging effect on the scabies mite and its eggs.

After intravenous administration of sodium thiosulfate is distributed in the extracellular fluid, excreted unchanged in the urine. Biological T 1/2 - 0.65 hours.

Sodium thiosulfate is non-toxic. In studies conducted on dogs, with continuous infusion of sodium thiosulfate, hypovolemia was noted, which is probably due to its osmotic diuretic effect.

It is used in a complex of means for detoxification in patients with alcoholic delirium.

Application of the substance Sodium thiosulfate

Intoxication with arsenic, lead, mercury, bromine, iodine salts, hydrocyanic acid and cyanides; allergic diseases, arthritis, neuralgia; scabies.

Contraindications

Hypersensitivity.

Use during pregnancy and lactation

Use during pregnancy is possible only in case of emergency. Reproductive studies in animals with sodium thiosulfate have not been performed. It is not known whether sodium thiosulfate can cause adverse fetal effects when taken by pregnant women and affect fertility.

Photo of the drug

Latin name: Sodium thiosulfate

ATX Code: V03AB06

Active substance: Sodium thiosulfate (Sodium thiosulfate)

Producer: Novosibkhimfarm, Moskhimfarmpreparaty them. N.A. Semashko, Pharmstandard-UfaVITA, Eskom NPK OAO, MTX Medical and Technological Holding, Binnopharm ZAO, Ozon Pharm OOO, Sintez OAO, Chemical Plant named after. L.Ya.Karpova (Russia)

The description applies to: 23.10.17

Sodium thiosulfate is a drug from the group of antidotes (antidotes). This complexing drug is used for poisoning, as well as in some other situations. We will talk about how to take sodium thiosulfate correctly further. To do this, consider the instructions for use of the drug.

What is the composition and form of the drug Sodium thiosulfate?

The pharmaceutical industry produces the drug in a colorless solution, it is transparent, without any foreign inclusions, the active compound is sodium thiosulfate. Auxiliary components of the drug are represented by water for injection, as well as sodium bicarbonate.

The drug is supplied to the pharmaceutical market in the form of ampoules of five and ten milliliters, which are packed in blister packs and packaged in cardboard packs. The antidote Sodium thiosulfate is dispensed by prescription. Shelf life does not exceed 5 years.

What is the effect of sodium thiosulfate solution?

The action of sodium thiosulfate on the body is detoxifying (relieves intoxication). The solution is effective in case of poisoning a person with compounds of lead, arsenic, mercury, as it contributes to the formation of non-toxic sulfites.

In addition, sodium thiosulfate forms less toxic compounds when a person is poisoned with cyanides.

What are the indications for sodium thiosulfate?

The drug Sodium thiosulfate instructions for use in ampoules allows you to use in the following cases:

When a person is poisoned with toxic compounds, for example: arsenic, iodine, mercury, lead, in addition, bromine, and also hydrocyanic acid;

In addition, they use the remedy for allergies, with identified arthritis and neuralgia inside and intravenously;

To cleanse the body;

In addition, in some situations, the remedy is prescribed in gynecological practice for.

What are the contraindications for the use of sodium thiosulfate?

Means Sodium thiosulfate (solution) instructions for use does not allow the use of identified hypersensitivity to the components of the drug.

What are the ampoules "Sodium thiosulfate solution" for oral and external use? What is the dosage of sodium thiosulfate?

Sodium thiosulfate in case of poisoning

In case of poisoning, sodium thiosulfate is taken orally 2 or 3 grams at a time. Intravenously administered in a dose of 5 to 50 milliliters, while exact dosage will be determined by the severity of the poisoning.

In case of cyanide poisoning, it is recommended to combine sodium thiosulfate with sodium hyposulfite, as well as with sodium nitrite. In this situation, it is important to administer the antidote to the patient in a timely manner, and the patient's condition should be monitored for 1 or 2 days.

sodium thiosulfate for scabies

For the treatment of scabies, sodium thiosulfate is rubbed into the affected areas for a couple of minutes in each part of the body: arms, legs, torso, in total, such a procedure will take 10-15 minutes. Then they take a break, waiting until skin dry and small crystals form on them.

Then re-rubbing medicinal product, then, when the medicine dries again, 6% hydrochloric acid is applied to the skin. You can't wash on this day. water procedures can be carried out three days after the therapy.

The use of sodium thiosulfate to cleanse the body

Sodium thiosulfate is used to cleanse the body. In this case, the reception of the funds is carried out within 10 days. One ampoule is dissolved in a glass of water and taken in the morning an hour, half an hour before breakfast 0.5 cups; in the evening, 30 or 60 minutes before dinner, the patient drinks the remaining half of the glass.

In the morning, after taking the drug, a person may experience some indigestion. During the ten-day course, the patient is advised to refrain from eating meat, milk, it is important to consume plenty of fluids, for example, it is worth taking citrus juices, previously diluted with water.

The result of cleansing the body with Sodium thiosulfate will be as follows: an improvement in the condition of the skin, nails and hair, it is noted, weight is reduced to some extent, nervousness and allergies disappear, and the condition of patients with such a dermatological problem as is alleviated. Before starting to carry out similar procedure it is important to consult a doctor.

Sodium thiosulfate - application in gynecology

In gynecology, sodium thiosulfate is used to treat infertility, while intravenous administration of the drug is combined with a session of the so-called plasmapheresis, in addition, intramuscular injections are indicated, and so on.

What are the side effects of sodium thiosulfate?

In some patients who use the drug Sodium thiosulfate, the development of allergic reactions is not excluded. In such a situation, it is recommended to suspend the further use of the remedy, and it is also important to consult a specialist.

Overdose of sodium thiosulfate

Cases of overdose of sodium thiosulfate have not been registered. However, if the patient simultaneously takes a large number of solution inside, it is recommended to urgently proceed to, and also, with, it is necessary to consult a doctor.

special instructions

Before using the ampoule with sodium thiosulfate, it is important to make sure that the solution is transparent, in addition, there should be no sediment in the preparation, and the appropriate marking should be present on the ampoule and on the medicine box.

How to replace sodium thiosulfate, which analogs to use?

There are no analogues of the drug Sodium thiosulfate.

Conclusion

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The course of this disease is difficult for many people to tolerate, it affects the skin and causes severe discomfort. Sodium thiosulfate in psoriasis has found its use for cleansing the body with the help of intravenous administration, external use or ingestion, according to doctors and patients, the drug has a positive effect in the treatment of the disease. Dermatologists prescribe this drug for internal body cleansing successful treatment psoriatic arthritis, allergies and psoriasis.

What is sodium thiosulfate

The release form of this medication is brackish-bitter granules without color and odor. Sodium thiosulfate is easily soluble in water and does not mix with alcohol. Available in ampoules as a solution. Here are some features of the effects of Sodium Thiosulfate on the human body:

• promotes the removal of toxins from the lymph and blood, other harmful compounds, the drug is activated in the intestines.
• inhibits the process of absorption by the mucous membrane dangerous compounds, prevents them from migrating to circulatory system.
• helps to increase intestinal motility, has a mild laxative effect. This helps the digestive tract to clear faster, which has positive influence for the work of others internal organs.
• due to the binding of toxins, heavy metals, sulfur molecules help to restore the body.

What is used for

Sodium thiosulfate has found its application in medical practice as an antitoxic, desensitizing, anti-inflammatory agent. This is the main direction for which sodium thiosulfate is used, so it has become effective tool with psoriasis. The cleansing, antitoxic effect is based on the ability of the drug to form non-toxic compounds with toxic elements. Sodium thiosulfate has antidote properties against benzene, copper, aniline, iodine, sublimate, phenols and hydrocyanic acid.

Purification with sodium thiosulfate

According to patients, this medication has a positive effect in the treatment of pathology. Cleansing with sodium thiosulfate helps in cleansing the body, and has other advantages, which are manifested as follows:

• reduced craving for alcohol;
• noticeably improves appearance skin, rejuvenated;
• the structure of the hair is restored;
• the head clears up;
• delamination of nails is suspended;
• there is an improvement in the condition with cholecystitis, atherosclerosis, osteochondrosis.

With psoriasis

The method of treatment of this disease is reduced to a deep cleansing of the body, which helps to alleviate the course of pathology and other chronic diseases. Sodium thiosulfate from psoriasis relieves the body of toxins accumulated over many years, helps to strengthen the immune defense. The doctor may prescribe droppers for psoriasis if the situation is very difficult and it is necessary to achieve positive results in as soon as possible.

People who took the drug leave positive reviews about sodium thiosulfate, claim that psoriasis goes away completely even with chronic form pathology. Usually, we are talking about stable remission if you drink sodium thiosulfate. In psoriasis, the drug has next exposure if taken regularly:

1. The drug has a cleansing effect on the lymph, blood. Penetrating into the intestine, sodium thiosulfate pulls together waste products, toxins that have entered the gastrointestinal tract from the blood, intercellular, interstitial fluid.
2. Sulfur molecules help bind heavy metals, which leads to a pronounced restorative effect.
3. The drug has a mild laxative effect, enhances intestinal motility, dilutes the contents, which contributes to the rapid removal of toxins.
4. The tool greatly slows down the process of absorption of toxic compounds of the gastrointestinal mucosa, prevents their penetration into the blood.

Sodium thiosulfate instruction

All symptoms of pathology are manifested outward signs, but the treatment of the disease is carried out not only outside, but also inside. The instruction of sodium thiosulfate includes several options for the use of this drug. For example, a 60% solution is well suited for external treatment of lesions; it is used only for external use. Good dynamics is shown by a compress with sodium thiosulfate, which is done at least 3 times a day. To cleanse the body of toxins, toxins, in order to improve immune protection, sodium thiosulfate is administered:

• inside through the mouth;
• intravenously by injection.

Intravenously

The attending physician should set the required dosage for the treatment of psoriasis, based on data on the age, severity of the patient's condition, weight, etc. Sodium thiosulfate intravenously is started only in severe cases of the disease, if oral administration has not given the desired result. Is used for intravenous injections 30% solution, packaged in 10 ml ampoules.

Sodium thiosulfate intravenously gives a quick effect, but it is better for a specialist to inject, because it is important to correctly administer the injection, calculate the dose. It is better to do this as prescribed by a doctor in a hospital. In the treatment of psoriasis, the speed of exposure is not as important as, for example, in case of poisoning, so it is recommended to take the drug orally. This option can be used independently at home.

inside

It is necessary to drink the medicine, observing the rules that do not harm your body. Sodium thiosulfate orally pure form not used, the contents are diluted in a liquid. To achieve the required concentration, you need 2 ampoules dissolves in 1 glass of water. This is enough to receive during the day. You need to drink half the medicine on an empty stomach in the morning, and the second - in the evening before dinner.

It is recommended to take 30 minutes before meals or 2 hours after. The duration of treatment is determined by the doctor and depends on the degree of psoriasis of the human body. Sometimes it is enough to take sodium thiosulfate for 4-5 days, but in some cases the course is 12 days.

Side effects of sodium thiosulfate

Manifestation negative consequences, as a rule, is associated with a violation of the rules for taking the medication or personal intolerance. Side effects of sodium thiosulfate may manifest as an allergic reaction due to intolerance to the substances in the preparation. When prescribing dosages of 20 ml and above, a significant loosening of the stool is observed, which also refers to the side effects of the medication. When the dose is reduced to 10 ml, the stool returns to normal, and the frequency of bowel movements is restored.

The patient may notice a change in smell, color stool, but this is not a reason for dose adjustment and is considered a normal reaction of the body when treating psoriasis with sodium thiosulfate. During therapy, the intestines are cleansed, so the consistency of the stool changes due to the removal of toxins from the body, this fact does not give reason to consider these signs as a side effect.

Sodium thiosulfate contraindications

The drug is not dangerous to humans, if you do not violate the rules of admission. Taking sodium thiosulfate for psoriasis is considered an effective option for treating the symptoms of the disease. There are certain restrictions on taking the medication in the following cases:

1. If identified hypersensitivity to active medicinal substance, which is noted in medical practice relatively often.
2. Contraindications for sodium thiosulfate include pregnancy. A toxic effect on the fetus has not been proven, but doctors recommend that you refrain from sweating the use of the drug during this period.
3. Manufacturers of the drug indicate a possible incompatibility with nitrates. especially if the drug is administered intravenously. It is recommended to check with a specialist in advance simultaneous reception drugs with Likopid, which is also often used in the treatment of psoriasis.
4. You can not use the remedy for hypertension, pathology of the cardiovascular, renal system.
5. You should not drink sodium thiosulfate in psoriasis in the presence of edema, regardless of the nature of origin. It is forbidden to carry out treatment with chronic disorders intestines, detection of malignant tumors.

The price of sodium thiosulfate

The cost in St. Petersburg and Moscow funds is on the same level. The price may vary depending on the place of sale or the manufacturer, the sale is carried out without a prescription. If desired, you can order the product from the online store with delivery. How much does sodium thiosulfate cost: injection solution 30%, price - from 88 rubles. Produced in ampoules of 10 or 5 ml, 10 pcs in a pack.

Video: how to drink sodium thiosulfate for psoriasis