Grammidin what antibiotic contains. Spray and lozenges Grammidin (children, Neo with anesthetic): instructions and use

"Grammidin", what helps this antibiotic - antiseptic? The medicine is intended for the treatment of infections and ailments of the throat and oral cavity. Tablets "Grammidin" instructions for use suggest taking with angina, stomatitis.

Composition and form of release

They are made in the form of tablets that need to be dissolved in the mouth. The pills have flat shape. Grammidin tablets, from which the medicine helps with pharyngitis, contain the active element gramicidin C in a volume of 1.5 mg and excipients. It is sold in blisters of 10 tablets. The package contains 2 blisters.

They also produce such varieties of medicines as:

1. "Grammidin for children" (yellow scarf on the package).
2. "Grammidin Neo" (green scarf).
3. Grammidin with Neo anesthetic (red).

Pharmacological properties

The action of the drug "Grammidin", from which it helps with sore throat, is due to the properties of its active element. The medicine has a bright antimicrobial effect, fights most microorganisms that provoke infectious pathologies of the oral cavity and pharynx.

The medication relieves inflammatory process, reduces discomfort in the throat and improves swallowing. The presence of an anesthetic in the composition allows you to get rid of pain symptoms in the throat and mouth. The patient after taking the drug feels significant relief. Patients say that it gets better even in the process of resorption of the tablet.

The medicine "Grammidin": what helps

The drug is prescribed for the treatment of the following pathologies:

• sore throats;
• tonsillitis;
• stomatitis;
• pharyngitis;
• periodontal disease;
• gingivitis;
• periodontitis.

Contraindications

The instruction prohibits the use of Grammidin for:

• breastfeeding;
• hypersensitivity to the composition of the drug "Grammidin", from which these tablets can cause allergies.

Caution is required when using the drug during pregnancy. You can take the medicine only according to medical prescriptions in a reduced dosage. At breastfeeding tablets are allowed. For this this process interrupt.

Medicine Grammidin: instructions for use

Tablets should be taken after meals. Should not be chewed. After using the medication, you can not eat or drink for 2 hours. Tablets "Grammidin" instructions for use instruct adults and children after 12 years of age to keep 2 pills in their mouths with an interval of 20 minutes. The number of such receptions reaches 4 per day. Therapy takes 5-6 days. The highest daily volume is 24 g.

"Children's Grammidin": application

The drug is prescribed to children from 4 years of age. Up to 12 years, it is necessary to dissolve 1 tablet 4 times a day. Older children are shown 2 tablets 4 times.

Instructions for use "Grammidin with anesthetic" and "Grammidin - Neo"

These drugs are consumed in the amount of 1 tablet. 3-4 pills are used per day. In case of complication of the disease in adults, the dosage is doubled. Take 2 tablets with an interval of 20 minutes.

Side effects

The medicine "Grammidin", instructions and patient reviews indicate this, is well tolerated, practically does not cause unacceptable reactions of the body. The minor disadvantages of the drug include a temporary loss of sensitivity of the tongue and an allergy, which manifests itself:

• rash;
• dry mouth;
• hives.

Throat pills rarely cause these symptoms.

Interaction with other drugs

The drug enhances the effect of antimicrobial agents. The drug is prescribed as part of complex therapy.

During pregnancy and lactation

Doctors prescribe a medicine, comparing the expected benefits for the mother and the harm to the child. During lactation, the drug is contraindicated.

Analogues of the drug "Grammidin"

Same active substance contain the following synonyms:

1. Gramicidin C.
2. Gramicidin C hydrochloride.
3. Grammidin Neo.
4. Grammidin Neo with anesthetic.
5. Children's with raspberry flavor.

Analogues that are also used for the treatment of tonsillitis and tonsillitis have a similar effect:

• Fervex for sore throat;
• Cefatrexil; Sumazid; IRS 19;
• Miramistin; Alphacet; Anti Angin Formula;
• Novosept Forte; Orelox; Septolete;
• Sanguiritrin; Laripront; Yoks;
• Ribomunil; Clarithromycin; Augmentin;
• Lidaprim; Perty; Taromentin;
• Ketocef; Cefosin; Nacef;
• Bicillin 3; Azitral; Cedex;
• Tsiprosan; Polyoxidonium; Sifloks;
• Zeff; Hyposol; Metovit;
• Liprokhin; Dr. Theiss Angi Sept; Sea buckthorn oil;
• Ecositrin; Children's Panadol; Iodinol;
• Cefat; Sumetrolim; Tomicid;
• Zetsil; Rovamycin; Aqualor;
• Hexoral; Arlet; Amoxisar;
• Stopangin;
• Cefspan; Cefazolin; Neo angina;
• Fromilid; Timentin; Flemoklav Solutab;
• Dr. Theiss Sage Extract with Vitamin C;
• Streptocide tablets; Abisil; Sumamed forte;
• Aphenoxin; Dr. Theiss Sage; Cefotaxime;
• Palettex; Dinabak; Angin Hel SD;
• Oksamp; Grunamox; Cefesol;
• Tonsilotren; Wilprafen; Sextaphagus;
• Ciprofloxacin; Solpadein; Ampicillin;
• Bicarmint; Nalgezin; doxycycline hydrochloride;
• Sumamed; Tsiprolet A; Pharyngosept;
• Bicillin 5; Amben; Azivok;
• Cefurabol; Methyluracil; Hexaspray;
• Hexalysis; Tercef; Zanocin;
• Sultasin; Strepsils; Microflox;
• Cifran; Tantum Verde;
• Dr. Theiss Echinacea extract;
• TeraFlu Lar; Biseptol; Zitrolide forte;
• povidone iodine; Wilprafen Solutab; Cephabol;
• Ciprobrine; ceftriabol; Falimint;
• Vocara; Hemomycin; Unidox Solutab.
• Klamosar; Ospeksin; Amoxicillin;
• Faringopils; Tonsilgon N; Hexadreps;
• Hexapneumine; Felexin; Vepicombin;
• Rulid; Vibramycin; Supero;
• Furacilin; Biodroxil; Panadol Extra;
• Bioparox; Cyprobid; smallpox;
• Erythromycin; Aldolor; Propolis tincture;
• Quipro; Doxylan; Cephalexin;
• Bicillin 1; Zinnat; Cliacil;
• Suprax; Geksoral tabs; Bactrim.

Price

In Moscow, you can buy Grammidin tablets of any variety (red, green, children's) within 207 - 300 rubles.

In Kyiv, the medicine costs 350 hryvnia.

The price in Minsk reaches 4-15 bel. rubles.

In Kazakhstan, the product is sold for 1270 tenge.

Grammidin (tablets for sore throat) - instructions for use, price, reviews, analogues

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Grammidin is an antibacterial drug for local application with various infectious and inflammatory diseases of the oral cavity and pharynx (pharyngitis, tonsillitis, tonsillitis, periodontitis, gingivitis, stomatitis).

Varieties, names, forms of release and composition

• Grammidin;
• Grammidin for children;
• Grammidin Neo;
• Grammidin with anesthetic;
• Grammidin with Neo anesthetic.

Varieties of Grammidin in everyday life are called official names (for example, Grammidin Neo, Grammidin with anesthetic, etc.). The only varieties of the drug that have a common name different from the official one are Grammidin with anesthetic and Grammidin with Neo anesthetic. These varieties are commonly referred to as "Grammidin Red", because the packaging of these tablets shows a red scarf. The packaging of the other varieties of Grammidin also show a scarf dyed in different colors. Moreover, each type of drug corresponds to the one shown on the package certain color scarf.

All varieties of Grammidin are produced in the same single dosage form - lozenges.

In the composition of all varieties of Grammidin as the main active component included gramicidin C in the following different dosages:

• Grammidin - contains 1.5 mg (1500 IU) of gramicidin C per tablet;
• Grammidin for children - contains 1.5 mg (1500 IU) of gramicidin C per tablet;
• Grammidin Neo - contains 3 mg (3000 IU) of gramicidin C per tablet;
• Grammidin with anesthetic - contains 1.5 mg (1500 IU) of gramicidin C per tablet;
• Grammidin with anesthetic Neo - contains 3 mg (3000 IU) of gramicidin C per tablet.

Additional active ingredients include varieties Grammidin for children, Grammidin Neo, Grammidin with anesthetic and Grammidin with anesthetic Neo. Moreover, Grammidin for children, Grammidin Neo and Grammidin with anesthetic contain one additional active component, and Grammidin with Neo anesthetic - two. The composition and dosages of the main and additional active components of all varieties of Grammidin are shown in the table:

Additional active ingredient cetylpyridinium chloride expands the spectrum of the antimicrobial action of the drug, since it has a detrimental effect on viruses, fungi and protozoa. And gramicidin, in turn, destroys bacteria.

Lidocaine hydrochloride and oxybuprocaine hydrochloride, being additional active components of Grammidin with anesthetic and Grammidin with Neo anesthetic, have an analgesic effect, relieving pain in infectious and inflammatory diseases of the oral cavity and pharynx.

Grammidin varieties include various excipients, as shown in the table below:

Grammidin and Grammidin with anesthetic are available in the form of round tablets, painted white or white with a yellowish tinge, and packed in 10 or 20 pieces.

Grammidin for children is produced in the form of round biconvex tablets, equipped with a chamfer (beveled edge) and engraved GR on one side. The tablets have a raspberry odor and are white or white with a yellowish tinge. Packed in cardboard boxes of 12, 18 and 24 pieces.

Grammidin Neo and Grammidin with Neo anesthetic are available as round, biconvex tablets, colored white and debossed with GR on one side. Packed in cardboard boxes of 12, 18 and 24 pieces.

Therapeutic action

Cetylpyridinium chloride, which is part of Grammidin for children, Grammidin Neo and Grammidin with Neo anesthetic as the second active substance, is a broad-spectrum antiseptic. It destroys viruses, protozoa, fungi and other microbes that cause infectious and inflammatory diseases of the oral cavity and pharynx. Thus, cetylpyridinium chloride expands antimicrobial spectrum actions of Grammidin, making the drug effective for the treatment of infectious and inflammatory diseases of the oral cavity caused not only by bacteria, but also by viruses, and protozoa, and fungi, and other pathogenic microbes.

In addition, cetylpyridinium chloride softens discomfort in the throat, facilitates swallowing and causes increased salivation, due to which microbes are mechanically removed from the surface of the mucous membranes of the mouth and throat.

Lidocaine hydrochloride, which is part of Grammidin with an anesthetic, and oxybuprocaine hydrochloride, which is part of Grammidin with Neo antiseptic, have an analgesic effect, stopping pain in the throat and oral cavity caused by infectious and inflammatory diseases.

Thus, all varieties of Grammidin reduce the severity of inflammation, soften the discomfort in the throat, make swallowing less painful and contribute to mechanical removal microbes from the mucous membrane of the mouth and throat, thereby facilitating the course of the disease and accelerating recovery.

Varieties with cetylpyridinium chloride (Grammidin for children, Grammidin Neo and Grammidin with Neo anesthetic) act not only on bacteria, but also on viruses, therefore they can be used for viral infections oral cavity and pharynx.

Teenagers over 12 and adults it is necessary to select Grammidin among the "adult varieties", such as Grammidin, Grammidin with anesthetic, Grammidin Neo and Grammidin with Neo anesthetic.

So, if a teenager over 12 years old or an adult has a presumably bacterial infectious and inflammatory disease of the oral cavity or pharynx (this is easy to understand by the presence of pus in the discharge), then he should choose Grammidin or Grammidin with an anesthetic. Just Grammidin is suitable for not too intense pain in the pharynx and oral cavity, and Grammidin with an anesthetic should be preferred for severe pain. In principle, it is possible to combine the use of Grammidin and Grammidin with an anesthetic, for example, using daytime Grammidin, and in the evening, before going to bed, Grammidin with an anesthetic to provide fast falling asleep and more or less comfortable sleep.

If a teenager over 12 years old or an adult has a presumably viral infectious and inflammatory disease of the oral cavity or pharynx (this is easy to understand by mucous secretions without pus impurities), then it is optimal to use Grammidin Neo or Grammidin with Neo anesthetic. Moreover, if the inflammatory process is accompanied by severe pain in the throat or oral cavity, then it is better to use Grammidin with Neo anesthetic. If the pain in the throat or oral cavity is not severe, then it is optimal to use Grammidin Neo. If necessary, you can combine Grammidin Neo and Grammidin with Neo anesthetic, using one or another drug, depending on the severity of the pain syndrome at the current time. For example, if the pain in the throat is severe, then Grammidin with Neo anesthetic is used, and if after two hours the pain syndrome is tolerable and not as pronounced as it was, then Grammidin Neo is used.

Instructions for use Grammidin

Grammidin can be used for children from 4 years and adults. In this case, children aged 4-12 years should dissolve 1-2 tablets 4 times a day, and adolescents over 12 years old and adults - 2 tablets 4 times a day. Maximum allowable daily dosage is 8 tablets.

Dissolve two tablets should be one after the other, and not simultaneously. That is, first a person must dissolve one tablet, and only after that put a second one in the oral cavity. Two tablets should not be placed in the mouth and sucked at the same time, as this will lead to less uniform distribution active substance on the mucous membranes of the oral cavity and throat and, accordingly, lower therapeutic efficacy of the drug.

The duration of Grammidin use is 5-6 days. If within a week the use of Grammidin did not bring relief, then you should stop taking the drug and consult a doctor.

Application instruction of Grammidin children's

Two tablets should be sucked in turn, first the first and then the second. Two tablets should not be sucked at the same time, as this reduces the exposure and distribution of the active ingredient on the mucous membranes of the oral cavity and pharynx, and thereby reduces the effectiveness of the therapeutic effect.

Tablets should be sucked in the mouth, waiting for their complete dissolution, without biting or chewing. During the resorption of tablets, it is released a large number of saliva to be swallowed. After resorption of the tablets, it is recommended to refrain from eating and drinking for 1 to 2 hours in order to ensure that the active component of Grammidin remains on the mucous membranes for as long as possible. Therefore, it is optimal to dissolve the tablets after eating, so that for 1 to 2 hours you can safely refrain from eating and drinking.

Instructions for use Grammidin Neo and Grammidin with Neo anesthetic

After resorption of the tablets, it is recommended to refrain from eating and drinking for 1 to 2 hours in order to ensure the longest possible stay of the active ingredients on the mucous membrane of the oral cavity and pharynx and, as a result, the best therapeutic effect. Therefore, it is recommended to dissolve the tablets after eating, so that you can safely withstand 1 to 2 hours without eating or drinking.

Children aged 4-12 years should dissolve 1 tablet 1-2 times a day, and adolescents over 12 years old and adults - 1 tablet 3-4 times a day. If within a week the condition has not improved, then you should stop taking the drug and consult a doctor.

Instructions for use Grammidin with anesthetic

After resorption of the tablet, it is recommended to refrain from eating and drinking for 1 to 2 hours in order to ensure the longest possible stay of the active components of the drug on the mucous membranes of the oral cavity and pharynx and, accordingly, the best therapeutic effect. That is why it is optimal to dissolve Grammidin with an anesthetic after eating, so that you can refrain from drinking and eating for 1-2 hours.

If you need to take two tablets at a time, then they should be sucked alternately. That is, first one tablet is placed in the mouth, completely absorbed, and only after that - the second tablet. You should not dissolve two tablets at once at the same time, as this can lead to an uneven and insufficiently long stay of the active components on the mucous membranes of the mouth and throat and, accordingly, reduce the effectiveness of the drug.

Children aged 3-12 years should dissolve 1-2 tablets 4 times a day, and adolescents over 12 years old and adults - 2 tablets 4 times a day. The maximum allowable daily dosage is the same for children and adults, and is 8 tablets per day. The duration of therapy is 5 - 6 days. If after a week there is no improvement, then you should stop taking Grammidin with an anesthetic and consult a doctor.

special instructions

Overdose

Influence on the ability to control mechanisms

Interaction with other drugs

Grammidin during pregnancy and breastfeeding

Varieties of Grammidin containing cetylpyridinium chloride(Grammidin for children, Grammidin Neo and Grammidin with Neo anesthetic), are contraindicated for use during the first trimester of pregnancy, that is, from the moment of conception until the end of the 13th week of gestation. In the second and third trimesters of pregnancy (from the 14th week of gestation until delivery), varieties of Grammidin with cetylpyridinium chloride can be used only in cases where the expected benefit to the woman exceeds all possible risks for the fetus.

Grammidin and Grammidin with anesthetic can be used during pregnancy of any period, including in the first trimester, but only in cases where the expected benefit to the woman outweighs all possible risks to the fetus.

In other words, it is recommended to refrain from using any Grammidin varieties during pregnancy, but if for some reason there is an urgent need to take pills, then the use of drugs is allowed.

Grammidin for children

General provisions

Children's Grammidin is no different from the "adult" varieties, since even the dosage of active ingredients in it is exactly the same as in "adult" products. So having a special variant of baby Grammidin is just marketing ploy a manufacturer who thus tries to secure sales for this target group as well. In practice, all Grammidins can be used for children from the age of four, and Grammidins with an anesthetic even from the age of three.

Grammidin, Grammidin for children and Grammidin with an anesthetic are optimal for use in children. These varieties of the drug must be used correctly so that they bring maximum benefit. So, the usual Grammidin the best way suitable for the treatment of infectious and inflammatory diseases of the oral cavity and pharynx caused by bacteria (this is easily determined by the presence of pus in the discharge). Grammidin for children is best suited for the treatment of infections caused by viruses (this is easily determined by the presence of only mucus and the absence of pus in the discharge). And Grammidin with an anesthetic is best used when the child has severe pain in the throat and mouth. Moreover, Grammidin with an anesthetic can be combined with regular Grammidin or children's Grammidin. In this case, the type of drug that is best suited to treat the current infection of the throat or mouth is selected, and additionally Grammidin with an anesthetic. Further, during the period of severe pain, the child is given a drug with an anesthetic, and in the rest of the receptions - the selected variety of Grammidin for the treatment of a bacterial or viral infection.

Thus, it can be summarized that Grammidin for children is optimal for viral infections of the oral cavity and pharynx for a child, and Grammidin is normal for bacterial infections. If there is strong pain in the throat or mouth, then it is optimal to add Grammidin with an anesthetic to Grammidin or Grammidin for children, which is given 1-2 times a day instead of the main drug.

Grammidin for children - instructions for use

If it is necessary to dissolve two tablets at a time, then this should be done alternately. That is, first give the child one tablet, wait until he dissolves it, and only after that give the second. Two tablets should not be given at once so that the child dissolves them at the same time, since this can lead to improper distribution and a decrease in the exposure time of the active ingredients on the mucous membranes of the mouth and throat and, accordingly, a deterioration in the therapeutic effect.

It is optimal to give tablets of any kind of Grammidin to a child after meals, since after resorption of the drug it is recommended to refrain from eating and drinking for 1 to 2 hours. The recommendation to refrain from drinking and eating is due to the fact that it is desirable that the active components of the drug remain on the mucous membranes of the mouth and throat as long as possible, providing a therapeutic effect. And if you eat or drink within 1-2 hours after resorption of the tablet, you can simply wash off the active substances from the mucous membranes of the mouth and throat, thereby stopping their therapeutic effect.

Dosages of Grammidin are the same for children 4-12 years old, but are different for different types of the drug. So, it is recommended to give varieties of Grammidin to children aged 4 to 12 years in the following dosages:

• Grammidin - give 1 - 2 tablets 4 times a day;
• Grammidin for children - give 1 tablet 4 times a day;
• Grammidin with an anesthetic (can be used by children from three years old) - give 1 - 2 tablets 4 times a day;
• Grammidin Neo - give 1 tablet 1 to 2 times a day;
• Grammidin with Neo anesthetic - give 1 tablet 1-2 times a day.

Side effects

Varieties of the drug containing cetylpyridinium chloride (Grammidin for children, Grammidin Neo and Grammidin with Neo anesthetic), in addition to allergic reactions, can cause organ dysfunction as side effects gastrointestinal tract(diarrhea, nausea).

Varieties of Grammidin containing anesthetics (Grammidin with anesthetic and Grammidin with Neo anesthetic) can, in addition to allergic reactions, cause temporary numbness of the tongue as a side effect. However, this numbness disappears within 30 to 40 minutes after the anesthetic wears off.

Thus, varieties of Grammidin as side effects can cause the following symptoms:

• Grammidin - only allergic reactions;
• Grammidin Neo and Grammidin for children - allergic reactions + diarrhea and nausea;
• Grammidin with an anesthetic - allergic reactions + numbness of the tongue;
• Grammidin with anesthetic Neo - allergic reactions + diarrhea and nausea + numbness of the tongue.

Contraindications for use

• breastfeeding period;
• Individual hypersensitivity or allergic reactions to any components of the preparations;
• I trimester of pregnancy (for Grammidin for children, Grammidin Neo and Grammidin with Neo anesthetic);
• Phenylketonuria (for Grammidin for children and Grammidin with an anesthetic);
• Children under 4 years of age (for Grammidin, Grammidin for children, Grammidin Neo and Grammidin with Neo anesthetic);
• Children under 3 years of age (for Grammidin with anesthetic).

Drug analogues

Unfortunately, only one variety of Grammidin has synonymous drugs - the usual Grammidin, which contains only gramicidin C as an active ingredient. Synonyms this drug are lozenges and topical solution Gramicidin and Gramicidin paste.

All other varieties of Grammidin (Grammidin for children, Grammidin Neo, Grammidin with an anesthetic and Grammidin with an anesthetic Neo) do not have synonymous drugs on the domestic pharmaceutical market.

However, all varieties of Grammidin have analogues that have a similar spectrum of therapeutic activity, but contain other active substances. These analogues of all varieties of Grammidin are shown in the table. For each variety, we have selected analogues in such a way that they contain active substances with a similar spectrum of action. For example, for Grammidin with an anesthetic, drugs that also contain antimicrobial and anesthetic components, etc., were selected as analogues.

Cheap analogues of Grammidin

What is better than Grammidin?

This means that for a certain person in one situation Grammidin will be the best, and in another case for the same person, on the contrary, this drug will turn out to be the worst, and the best will be completely different. Therefore, it is simply impossible to say what is better than Grammidin. In order to choose the best drug for a particular situation, it is recommended to try several similar drugs and evaluate their effects in practice, thus choosing what is best for a particular person.

Gramicidin C. This component has an antimicrobial effect, which helps to restore normal state mucous membranes. Bactericidal is aimed at combating gram-positive and gram-negative bacteria, which are the causative agents of infectious diseases of the oral cavity. The drug enhances the permeability of the membranes of microbial cells, which leads to their death.

At the time of application this tool significantly increased salivation, which contributes to effective cleansing oral cavity from causing infection bacteria and their metabolic products. Dosage form with an anesthetic contains lidocaine and menthol, which eliminate pain and facilitate swallowing. The anesthetic works within 30-40 minutes. The drug potentiates the action of other antibiotics.

The drug "Grammidin" is available in the form of tablets for resorption.

Indications for use

Instructions for use

The tablet must be put on the tongue and kept in the mouth until completely dissolved, without chewing. In the case of taking 2 "Grammidin" at a time, you must take the first tablet, then you should wait 20-30 minutes and take the second tablet in the same way.

After taking the drug for 1-2 hours, you can not eat or drink.

Contraindications and side effects

Usually occurs without side effects. In rare cases, the drug may cause allergic reactions or a short-term loss of sensation of the tongue.

Grammidin is an antiseptic local action, intended for the treatment and relief of symptoms of inflammation in the mouth and throat. It is often used to combat seasonal colds and dental problems. High efficiency, easy application and affordable price made Grammidin lozenges one of the most popular remedies for sore throats among the people. Today we will tell you in detail about the composition of this drug, correct application and possible contraindications.

Pharmacological action and composition of Grammidin

Name trademark Grammidin is consonant with the main active ingredient of this drug - the antibiotic gramicidin C. It has a very wide spectrum of bactericidal action, and quickly copes with almost any microbes that infect the oral cavity and human pharynx. This antibiotic is often used not only by therapists and pediatricians, but also by dentists.

The dissolution of tablets promotes profuse salivation, and due to this, the antibiotic quickly and evenly spreads through the oropharynx. Saliva helps to wash away the waste products of microbes, which is also important for get well soon. Grammidin weakens cell membrane bacteria, and they quickly die. A few medicinal forms the drug make its use as convenient as possible.

Grammidin release form

The drug is available in three forms:

Grammidin - yellowish sucking tablets white color, each contains 1.5 mg of the antibiotic gramicidin C, as well as a number of excipients (lactose, sugar, methylcellulose, calcium stearate). Tablets are in blisters of 10 pieces, each carton contains two blisters;

Grammidin Neo - convex sucking tablets with menthol flavor, on one side they have the inscription "GR". In addition to the antibiotic gramicidin at a dosage of 3 mg, they added one more active substance - cetylpyridinium chloride. This ingredient softens pain in sore throat arising from swallowing. Excipients Grammidina Neo: silicon dioxide, potassium acesulfate, magnesium stearate, menthol, sorbitol and talc. The drug is available in blisters of 6 or 9 pieces, which are packed in cardboard boxes of 4 or 2 blisters, respectively;

Grammidin with anesthetic - convex sucking tablets with a taste of lemon, black or. Here, 10 mg of the anesthetic lidocaine is added to 1.5 mg of the antibiotic gramicidin, which perfectly removes sharp pain in the throat with angina. Excipients: Eucalyptus oil, lemon acid, hydroxypropyl cellulose, menthol, aspartame, mannitol and fruit flavor. The tablets are packaged in the same way as Grammidin Neo.

Indications and contraindications for use

Preparations from the Grammidin series are prescribed in the treatment of the following inflammatory diseases:

If the disease is accompanied by acute pain syndrome, it is better to take Grammidin with an anesthetic. As for contraindications, there are none - the drug is prescribed with caution during pregnancy. It is contraindicated for nursing mothers.

How to take Grammidin

Adult patients are prescribed two tablets of Grammidin 4 times a day or one tablet of Grammidin Neo 4 times a day for one week. You need to dissolve first one, and then immediately the second tablet, and it is better not to do this on an empty stomach, because after taking the drug you can not eat and drink for two hours. The slower the process of resorption of the tablets, the better the therapeutic effect. Grammidin with an anesthetic during the treatment of severe, painful sore throat can be taken more often, but it is still not recommended to dissolve more than six tablets per day. Children aged four to twelve years are prescribed one tablet of regular Grammidin (1.5 mg dosage) three times a day.

Vacation and storage conditions

The drug can be freely purchased at any pharmacy without a medical prescription, but you should not do this. There are precedents of allergic reactions, both to the active and to the auxiliary components of Grammidin. Your doctor, based on all previous cases drug allergy you or your child will be able to give competent advice on the choice of antiseptic for the treatment of sore throat.

Grammidin is a topical antibacterial drug that increases the permeability of bacterial cells.

The use of the drug increases salivation, which leads to increased excretion pathogenic microflora from the body.

On this page you will find all information about Grammidin: complete instructions on application to this medicinal product, average prices in pharmacies, complete and incomplete analogues drug, as well as reviews of people who have already used Grammidin. Want to leave your opinion? Please write in the comments.

Clinical and pharmacological group

Antibacterial agent, has a bacteriostatic effect (Streptococcus pneumoniae, meningococci, gonococci, pathogens anaerobic infection) and at high concentrations bactericidal effect on Streptococcus spp. and Staphylococcus spp.

Terms of dispensing from pharmacies

Released without a prescription.

Prices

The cost of Grammidin varieties in pharmacies of Russian cities currently fluctuates within the following limits:

• Grammidin Neo, 18 tablets - 190 - 245 rubles;
• Grammidin for children, 18 tablets - 203 - 296 rubles;
• Grammidin with Neo anesthetic, 18 tablets - 210 - 279 rubles.

Release form and composition

Grammidin lozenges are made in the following variations:

1. Grammidin - white and yellowish tablets, each containing 1.5 mg of Gramicidin C, as well as excipients: milk sugar, calcium stearate, methylcellulose, sugar). In packs of 10 tablets.
2. Grammidin with anesthetic - convex suckable tablets with lemon, blackcurrant or raspberry flavor. Here, 10 mg of the anesthetic lidocaine is added to 1.5 mg of the antibiotic gramicidin, which perfectly relieves acute sore throat with sore throat. Excipients: eucalyptus oil, citric acid, hydroxypropyl cellulose, menthol, aspartame, mannitol and fruit flavor.
3. Grammidin NEO are white round tablets containing 1 mg of cetylpyridinium chloride and 3 mg of Gramicidin C each. Additional components of the drug are: colloidal silicon dioxide, magnesium stearate, talc, sorbitol, mint flavor, acesulfame potassium. 6 or 9 tablets per pack.

Pharmacological effect

The main component gramicidin C has a pronounced antimicrobial effect against the most common pathogens. infectious diseases pharynx and oral cavity. The drug effectively fights harmful microorganisms, reduces inflammation, facilitates swallowing and softens discomfort in the throat.

The anesthetic included in Grammidin has a local anesthetic effect and effectively eliminates pain in the pharynx and oral mucosa. The tool relieves pain quickly enough: relief can be felt almost immediately after the tablet is completely resorbed.

Indications for use

What helps? The medicine Grammidin has a pronounced therapeutic effect for infections of the throat, gums and tongue.

Indications for appointment:

Grammidin tablets have a pleasant mint flavor. However, this does not mean that the drug can be taken uncontrollably.

Grammidin - an antibiotic or not?

Yes, it's an antibiotic. Main active substance is gramicidin C - antibacterial agent for local use, discovered back in the forties of the last century. The compound produced by Bacillus brevis bacteria has been refined for several decades and finally found application - local antibiotic therapy of infectious diseases of the respiratory system (tablets for resorption in the oral cavity).

Gramicidin is active against a wide range pathogenic microbes: staphylococci, streptococci, some anaerobes. The main sphere of its bactericidal activity is gram-positive microorganisms, and they do not develop resistance to this at all. antimicrobial drug. It acts bactericidal by increasing the permeability of the cell cytoplasmic membrane.

Contraindications

Tablets Grammidin instructions for use prohibits when hypersensitivity to its components, as well as during breastfeeding. During pregnancy, treatment with this drug is allowed only after consulting a doctor and should be carried out with caution (limiting the dose and frequency of administration). If it is necessary to use Grammidin during lactation, breastfeeding is stopped.

Use during pregnancy and lactation

Grammidin during pregnancy is not prescribed due to the possible adverse effect its components on the body of a woman and fetus.

This medicine also does not treat the throat during feeding. If the doctor strongly recommends that a nursing mother treat pharyngitis with Grammidin, breastfeeding should be stopped for the duration of the course of therapy.

It must be understood that taking the drug during pregnancy or breastfeeding can provoke metabolic disorders, depression of immunity, allergization.

Instructions for use

The instructions for use indicate that Grammidin and Grammidin with an anesthetic are prescribed for adults and children (from 12 years old) two tablets each. They should be sucked one by one within 20-30 minutes after eating. After using the drug, it is not recommended to eat and drink for 1-2 hours. Taken 4 times a day. Children under 12 years of age are prescribed 1-2 tablets 4 times a day. Course duration - 5-6 days.

Grammidin NEO is prescribed for adults and children (from 12 years old) 1 tablet 3-4 times a day, and for children from 4 to 12 years old - 1 tablet 1-2 times a day. The duration of the course is 7 days.

Side effects

Varieties of Grammidin as side effects can cause the following symptoms:

• Grammidin - only allergic reactions;
• Grammidin Neo and Grammidin for children - allergic reactions + diarrhea and nausea;
• Grammidin with an anesthetic - allergic reactions + numbness of the tongue;
• Grammidin with anesthetic Neo - allergic reactions + diarrhea and nausea + numbness of the tongue.

Overdose

To date, cases of overdose with Grammidin children's lozenges have not been reported.

special instructions

Before using the drug, you must carefully read the instructions for it. There are several special instructions that you should pay attention to:

• The use of the drug does not affect the speed of psychomotor reactions and concentration.
• As an auxiliary component, the composition of the drug includes sugar, this must be taken into account for people with concomitant diabetes mellitus.
• The use of Grammidin children's tablets enhances the therapeutic effect of other antibacterial drugs, so their combined use is often recommended.

In the pharmacy network, Grammidin children's lozenges are dispensed without a prescription. If you have any doubts or questions regarding their use, you should consult your doctor.

drug interaction

As for the interaction of Grammidin with other drugs, the drug is capable of enhancing the various effects of many other antibiotics, which are prescribed both locally and systemically.

The drug is produced pharmaceutical company in the form of tablets, which have either a white or white-yellowish color. One standard packaging cardboard contains two plastic blisters, ten small tablets each.

The composition of the drug includes the active substance, as well as several additional components. The antibiotic gramicidin C with the addition of cetylpyridinium chloride and oxybuprocaine is the main component of the tablets. Inactive substances include: calcium stearate, milk sugar, sugar and methylcellulose.