Kagocel is the best antiviral drug for the prevention and treatment of SARS and influenza. Antiviral agents Kagocel - “Does Kagocel help? reception with timely and delayed treatment of acute respiratory viral infections

Kagocel is one of the few immunomodulatory drugs in tablets, which are characterized by powerful activity against viral infection. The effectiveness of the drug is confirmed by the ability of its components to inhibit (suppress) the activity of rotavirus and herpes infections, SARS and influenza. According to the principle of reaction to the virus, the drug is similar to other drugs - therapeutic effect is achieved by synthesizing human interferon (endogenous protein gamma globulin) in the blood - an organic antibody with powerful antiviral activity.

The production of antibodies by the human body begins with cellular activation of lymphocytes, granulocytes, macrophages, fibroblasts, and endothelial cells. After taking Kagocel, the maximum cellular concentration of produced immunoglobulin reaches critical point. By activating the enzyme components (protein kinase and adelityl synthetase), gamma globulin inhibits the synthesis (penetration) of the protein and RNA of the virus.

talking plain language- Being essentially an inducer of the immune response, the drug literally forces the body to produce loading dose antiviral antibodies.

Kagocel has a high duration of active action, is used at any stage of the disease, is easily excreted from the body (up to 99% of the dose on the 7th day), has no cumulative properties and side effects.

According to the instructions for use from the manufacturer Kagocel - antiviral drug approved by the Ministry of Health of Russia as an effective tool for the prevention and treatment of acute respiratory viral infections, influenza and herpes. Since 2006, the medicine has been included in the public procurement of essential medicines.

For what diseases is Kagocel prescribed?

The drug is prescribed by a doctor for symptoms viral etiology:

• SARS;
• ORZ, ;
• diseases of the mucous membranes in the form of grouped bubble rashes ();
• cytomegalovirus infection;

The effectiveness of Kagocel in rotavirus - what is the essence of the treatment

Organically persistent (persistent) rotavirus significantly reduces immune defenses infected person. The deficiency of interferon is especially noticeable during the period of children's seasonal morbidity. When the immune response is activated, the elimination (removal) of the virus from the body occurs quickly and, as a result, a quick recovery occurs.

With the development rotavirus disease taking Kagocel provokes the concentration of active immune cells in the intestine as early as 4 hours after the first tablet. This allows you to significantly reduce the manifestations of intoxication, normalizes body temperature, quickly stops signs of dehydration by stabilizing the stool and stimulates the recovery function. epithelial cells intestinal mucosa.

The inclusion of Kagocel in the complex treatment of rotavirus significantly reduces the risk of re-infection, which prevents further spread of the infection. The reason for this is the influence of Kagocel on the reproductive function of the viral particle in the body. This fact is clinically identified and substantiated by leading virologists according to laboratory studies of the interaction of gamma globulin to infection.

Schemes of taking Kagocel tablets for rotavirus in children

• the first two days, one tablet twice a day;
• the next two days, one tablet per day.

Children of the older age category(from 6 years old) it is recommended to take the medicine in the following proportions:

• the first two days on a tablet three times a day;
• then two days on a tablet twice a day.

The total number of Kagocel tablets per course of treatment should not exceed 10 per person.

Course therapy significantly accelerates the recovery period, prevents the spread pathogenic microflora on other organs, contributes to the rapid localization of the infectious focus. The effectiveness of the treatment of adults with a course of the drug was studied in terms of dynamic indicators and laboratory analysis. Based on the data obtained, it was concluded that overall picture spastic manifestations of the first two days does not change. Against the background of a decrease in the respiratory clinic, a decrease in the signs of rhinitis is recorded on the third day, and a decrease in the frequency of diarrhea on the fourth day. At the same time, already on the second day the patient notes an improvement in well-being and the appearance of appetite.

Schemes for the prevention and treatment of viral disease with Kagocel in an adult patient

Before talking about the schemes for taking Kagocel tablets for various diseases, it should be noted that the medicine is intended for oral (internal) use. During treatment, the tablet can not be divided in half, broken into pieces, tear off the film shell.

The principle of the drug regimens developed by the manufacturer is aimed at the formation of a shock immune response. Consistent dosage reduction provides a long-lasting protective barrier.

With absence positive results during the first three days of using Kagocel, the doctor is allowed to adjust the prescribed course, taking into account medical indicators in dynamics.

Table of application of the drug Kagocel (dosage for adults)

In cases of epidemics of a viral disease, it is advisable to take preventive measures with the use of the drug in accordance with the presented norms. The course of prevention and treatment with Kagocel should not exceed 3 times 2 days of taking tablets and two consecutive 5-day intervals.

With the active stage of herpes, it is better to use a loading dose of Kagocel - 3 tablets per day for 5 days.

Unfortunately, the manufacturer does not exactly indicate how to drink a Kagocel tablet. However, based on the general medical practice, usually medicines are washed down with plain water, it can be boiled at room temperature. The medicine should not be taken with alcohol, strong coffee or hot tea.

Schemes of taking the drug Kagocel for children

The child's body is most vulnerable during the off-season change of weather. Most often, children become infected with viruses, being constantly in a certain society - for example, in kindergarten or school class. For the development of an epidemic, close contact of several persons with an infected child is sufficient. The conditions of accumulation of children in one room contribute to the rapid spread of the virus. Therefore, it is very important to notice the symptoms in time and take appropriate safety measures.

Table of reception of Kagocel for children of different age categories

In order to medical therapy for children under 6 years of age, a 4-day course of Kagocel is carried out. For older children (up to 12 years old), 10 tablets are used in one course.

According to the instructions, the duration of the course in the prevention of viral diseases in children under 6 years of age can be carried out in a month, with the obligatory observance of 5-day intervals.

Kagocel during pregnancy and breastfeeding - can I take it?

Based on hypoallergenic and non-toxic active component, and taking into account the absence side effects drug, many patients believe that Kagocel can be taken during interesting position, both for the purpose of prevention and during illness. Understanding this issue, let us turn to the results of laboratory analytics in the study of the effect of the drug on a living organism.

Following the unanimous opinion of leading immunologists, as well as paying attention to the instructions of the drug manufacturer, the drug is not recommended for use during pregnancy. There is a hypothesis about the origin pernicious influence acting immunoglobulin on the organic tissue of the fetus. This threatens with intrauterine immune failures of a small organism, which in the future can provoke possible complications. These concerns are related to the ability of Kagocel to penetrate the placental barrier.

The concentration of the drug in the composition of breast milk is confirmed clinical analyzes. Such milk is harmful to the child, because it threatens the development of immune failures of a fragile organism.

Given the data obtained, the vast majority of doctors recommend that patients refrain from using Kagocel during pregnancy and lactation. If such recommendations cannot be avoided, short-term breast weaning is allowed during the course of treatment. In such cases, the interval must be maintained - from the moment of taking the first tablet to a week after the end of the course, feed the child breast milk it is forbidden.

Is it possible to combine a course of treatment with Kagocel and alcohol?

Taking medication and alcoholic beverages at the same time is strictly prohibited. Under the influence ethyl alcohol when stimulating the produced interferons, complications may occur in the form of severe forms psychosomatic nervous disorders. With alcohol abuse, these disorders can become irreversible.

Contraindications and side effects of Kagocel

Contraindications when taking the medicine include allergic reactions to the medication, pregnancy and breast-feeding. Due to the lack of confirmed information on the effect of the drug on children under 3 years of age (no studies have been conducted) - according to the instructions for Kagocel, this category is also included in contraindications.

Careful adherence to medical prescriptions minimizes the occurrence side effects from taking medication.

The appearance of these symptoms is most often associated with individual intolerance to one of the components that make up the drug. Such signs of intolerance include atopic rhinitis, muscle weakness, slight irritability.

For patients with body weight below normal, the drug should be administered carefully, individually selecting the daily or course dosage. The necessary correction of treatment should be carried out under constant monitoring of the dynamics of the patient's condition.

Why does the temperature rise after taking Kagocel?

The composition of Kagocel does not include substances that have a particular effect on temperature regime body of the patient during the illness. When treating, it should be remembered that the drug is an additional medicine and is in no way able to cope with it alone. severe infection without prior prevention.

Signs of high temperature indicate the progression of infectious pathology. This means that the patient needs an urgent consultation with a doctor in order to prescribe antibacterial and immunostimulating therapy at the same time.

The effect of Kagocel on reproductive function

To date, disputes of medical luminaries about the “spicy” side effect of Kagocel for the strong half of humanity still do not stop. Let's understand why this antiviral drug can be harmful for boys and for men.

Fundamental chemical reaction medicines based on the substance gossypol. It is a natural polyphenol from a number of enzyme dehydrogenase inhibitors. The organic compound is used in China as oral contraceptive for men. In addition to antiviral and antimicrobial properties, this antioxidant inhibits the development of male germ cells, which can cause infertility.

According to the manufacturer, Kagocel does not break down during organic replication, but no supporting studies have been provided. Therefore, it is quite logical that the presence of bound gossypol in the composition of the drug does not exclude minimum opportunity its accumulation in the body with frequent use of the drug. This fact causes fair concern about the sexual health of boys, especially during the formation and maturation of spermatozoa.

Comparison of Kagocel with other antiviral drugs

For some reason, we are convinced that the sooner we start treatment, the sooner we will recover. Everything is used, from grandmother's jam and honey to well-known antiviral drugs. Fortunately, the modern choice of pharmacy offers is replete with names. Of course, before choosing a particular medicine, you should consult your doctor. But to learn a little more information about existing and popular antiviral drugs for general development not prevent. We present to you small review analogues of Kagocel and their comparison with the original.

Remantadin (price about 70-90 rubles)

When choosing which is better Kagocel or Remantadin, you need to know about the advantages and disadvantages of each of the drugs.

For example, Remantadine is based on adamantane derivatives known for their effectiveness against group A viruses in the early stages of treatment. The drug has been produced since 1963. Since the established modifications of the A group of viruses resistant to adamantanes are relevant today, the medicine is considered obsolete.

Kagocel, according to the manufacturer, has therapeutic effect and for more later dates disease development. In addition, the operating principle this tool does not allow viruses to develop resistance (resistance), since interferon molecular cells absolutely do not care what "enemy" - it must be destroyed.

Ingavirin (price up to 450 rubles)

The activity of Invagirin is due to the synthesized biogenic aminohistamine, which takes part in the immune reactions of the body and has a virucidal (disinfectant) effect against adeno and rhinoviruses, viruses of groups A, B, and parainfluenza. Ingavirin splits the pathogenic virus, preventing its reproduction.

The action of Kagocel is based on a plant component. The drug starts natural processes protective functions to reduce the severity of the disease without preventing infection.

Ergoferon (about 350-370 rubles)

Ergoferon is a drug based on the homeopathic component of human interferon. It has a very mild effect, so it is not suitable for all patients - in practice, there have been cases when patients did not feel any improvement at all when taking Ergoferon. The phenomenon is explained by the individual sensitivity of the organism to the components of the remedy. In medicine, it is widely used for the treatment and prevention of a special category of the population - children from 6 one month old, pregnant and lactating mothers.

Compared to Ergoferon, Kagocel has a more powerful effect, so the manufacturer limited the circle of consumers in advance. For pregnant and lactating mothers, as well as children under 3 years old, the use of Kagocel in the treatment of a viral infection is not allowed.

Oscillococcinum (cost 460 rubles)

The homeopathic remedy Oscillococcinum is based on natural ingredients - an extract of the liver and heart of Barbary ducks. The drug is taken exclusively on prescription for no more than 2-3 days. When used for prevention purposes, it is necessary to drink a much smaller dose than Kagocel (once a week).

The main difference between the two drugs is that therapeutic effect prophylaxis with Kagocel is longer than with Oscillococcinum.

Cycloferon (cost up to 300 rubles)

Both medicines are excellent cellular immunity and inhibit the development viral pathology. Despite the content of another active ingredient in Cycloferon (meglumine acridone acetate), the effect on the body of medicines is identical.

The disadvantages of Cycloferon is the existence of serious side effects - the remedy should not be taken by allergy sufferers, children under 4 years of age and people with erosive pathologies of the gastrointestinal tract, liver. In the treatment with Cycloferon, a longer period is required until complete recovery - the drug acts slowly and is quickly excreted from the body.

Amiksin (price up to 900 rubles)

This is a more expensive analogue of Kagocel based on tilorone. It has wide range impact, as it is widely used in the treatment of tuberculosis, encephalomyelitis and viral hepatitis A, B, C. It is known for its properties to enhance the formation of all types of interferon, participates in protein synthesis and inhibits the reproduction of the virus. Very convenient to use - for prevention, one tablet is enough at any time of the day. The concentration of the active substance Amiksin in the patient's blood is reached in 12 hours (compared to Kagocel, the peak accumulation is not earlier than after 2 days).

A significant difference between the drugs is the restriction on the age of the consumer. Amiksin should not be drunk by children under the age of 7, while Kagocel is allowed to be taken by children from 3 years old.

The cost of the medicine Amiksin justifies its rapid effectiveness, widespread use and accelerated onset. therapeutic effect for an infection.

The combination of Kagocel in combination with other antiviral drugs

The high level of interaction of Kagocel with other antiviral drugs makes it possible to use the drug in comprehensive courses drug therapy. Against the background of the general impact, the elimination viral symptoms occurs faster, which significantly reduces the risk of serious consequences.

It is important to know that a complex intake of antiviral drugs is advisable in the first days of therapy.

Arbidol

Both drugs have the same pronounced effectiveness against viruses. Distinctive feature Arbidola is his active substance- umifenovir. The component is much more effective in stimulating the formation of immunoglobulin in the human body, so the drug is ideal for treating an existing infection. The action of Kagocel is more aimed at preventing the disease, so the drug is excellent during the epidemic period.

The complex of treatment with both drugs is effective in cases of using Arbidol for early stages development of the disease, and Kagocel at later stages.

Viferon

Viferon is a ready-made interferon isolated in a laboratory from a person. Synthetic Kagocel has the ability to enhance immune production when simultaneous reception immunostimulating agents (additive effect). Since there are no contraindications for the use of Viferon and Kagocel, both drugs work great together.

Antibiotics

In combination with antibiotics, Kagocel plays important role. Under the action of an antibiotic, the drug inhibits the development of pathogenic viruses, stimulating the body's response. At the same time, against the background of a plant inhibitor, the antibiotic destroys the weakened viral bacterium.

Treatment with Kagocel in tandem with antibiotics is prescribed by a doctor if there are suspicions of the development of complicating viral disease factors.

Ingavirin

Despite the fact that both drugs have sufficient antiviral properties, it is not recommended to use them at the same time, since Ignavirin has a number of contraindications when interacting with other antiviral drugs.

Acyclovir

Conducted medical research the high efficiency of Kagocel in combination with Acyclovir was proved - herpes manifestations in the observed patients disappeared on the third day from the onset of the disease. Patients noted a significant improvement in the condition, a decrease in pain, itching and burning in the area of ​​the vesicles.

It is perfectly compatible with Kagocel due to its pronounced antitumor and anti-inflammatory effect. Since cycloferon has minor contraindications, the drug should be taken with caution in patients with impaired liver and gastrointestinal tract, before the course of treatment, it is necessary to consult a doctor about the harmlessness of this compatibility for your body.

Antigrippin

The action of Antigripin is based on the components of the drug - homeopathic substances of plant and mineral origin. This property works more as a lead - it reduces the tendency to infection by increasing the body's immune resistance.

The main advantage of Antigrippin is a mild effect on the body and complete absence contraindications. In addition, the medicine is much cheaper than Kagocel and is approved for use in the treatment of children after a year.

Because the drug has slow cycle action, it is advisable to use a homeopathic remedy in combination with more strong medicine, for example, Kagocel.

Not everyone can afford to fork out for an expensive remedy for flu or herpes. Cheap analogues are good, but as statistics show, the effect of drugs differs significantly from each other. In order not to be mistaken in the choice of pharmacological proposals, do not be lazy to once again ask the therapist about substitutes expensive drugs. Kagocel is one of the high-quality analogues in terms of relatively inexpensive price. The effectiveness of this tool has been proven by time and positive feedback patients.

The main mechanism of action of Kagocel is the ability to induce the production of interferon. Causes the formation in the human body of the so-called. late interferon, which is a mixture of alpha and beta interferons with high antiviral activity.

Stimulates the production of physiological amounts of interferon gamma. Causes the production of interferon in almost all populations of cells involved in the antiviral response of the body: T- and B-lymphocytes, macrophages, granulocytes, fibroblasts, endothelial cells.

When administered in therapeutic doses, it is non-toxic and does not accumulate in the body. The drug does not have mutagenic and teratogenic properties, is not carcinogenic and does not have an embryotoxic effect.

For prophylactic purposes, the drug can be used at any time, incl. and immediately after contact with the source of infection.

Kagocel instructions for use

Tradename - Kagocel(kagocel)
Country of origin - Russia.
Manufacturer - Nearmedic-Plus CJSC.

Forms of release and composition

Tablets Kagocel. 1 tablet contains Kagocel - 12 mg/25 mg.
In a blister pack 10 pcs., in a carton pack 1 pack.

Excipients: potato starch, calcium stearate, lactose.
Composition by components: kagocel, lactose, calcium stearate, potato starch.

Indications for use

Kagocel is effective in the treatment of diseases caused by viruses: influenza, SARS (acute respiratory viral infections). Also, the drug is used to treat herpes, urogenital chlamydia.

The drug is used to treat adults and children over the age of 6 years with various diseases viral etiology, including:

• prevention and treatment of influenza and other acute respiratory viral infections in adults;
• treatment of influenza and other acute respiratory viral infections in children aged 6 years and older;
• treatment of herpes in adults.

The drug can also be used in complex treatment urogenital chlamydia.
In addition, the drug can be used as prophylactic during epidemics of acute respiratory viral infections and flu.

Pharmacological group

• Antiviral (with the exception of HIV) agents.
• interferon inductors.

pharmachologic effect

When one dose of Kagocel is taken orally, the interferon titer in the blood serum reaches its maximum values ​​after 48 hours. The dynamics of interferon accumulation in the intestine when the drug is taken orally does not coincide with the dynamics of titers of circulating interferon. In the blood serum, the content of interferon reaches high values ​​only 48 hours after taking Kagocel, while in the intestine the maximum production of interferon is noted already after 4 hours.

Kagocel, when prescribed in therapeutic doses, is non-toxic, does not accumulate in the body. The drug does not have mutagenic and teratogenic properties, is not carcinogenic and does not have an embryotoxic effect.

Dosage and administration

For the treatment of influenza and SARS in adults appoint in the first two days - 2 tablets 3 times a day, in the next two days - one tablet 3 times a day. In total, the course - 18 tablets, the duration of the course - 4 days.

Prevention of respiratory viral infections in adults carried out in 7-day cycles, two days - 2 tablets 1 time per day. 5 days break, then the cycle repeated. The duration of the prophylactic course is from one week to several months.

For the treatment of herpes in adults appoint but 2 tablets 3 times a day for 5 days. All for the course - 30 tablets, course duration - 5 days.

For the treatment of influenza and ARVI in children over 6 years of age appoint in the first two days - 1 tablet 3 times a day, in the next two days - one gabdetka 2 times a day. Total for the course - 10 tablets, course duration - 4 days.

Prevention of influenza and SARS in children aged 6 years and older carried out in 7-day cycles: two days - no 1 tablet 1 time per day. 5 days break, then repeat the cycle. The duration of the prophylactic course is from one week to several months.

Contraindications

Kagocel is contraindicated if the patient has hypersensitivity to the components of the drug, which is of an individual nature. Also given medicinal product do not apply to the treatment of children under the age of six years.

Hereditary galactose intolerance, Lapa lactase deficiency, malabsorption of glucose-galactose.

special instructions

The greatest efficiency in the treatment with Kagocel is achieved when it is prescribed no later than the 4th day from the start. acute infection. For prophylactic purposes, the drug can be used at any time, incl. and immediately after contact with the infectious agent. Kagocel goes well with other antiviral drugs, immunomodulators and antibiotics.

Side effects

Usually the drug is well tolerated by patients, in very rare cases allergic reactions may develop.

Interaction

At simultaneous application Kagocel with other antiviral drugs, immunomodulators and antibiotics, an additive effect has been described.

Pregnancy and lactation

The drug is not used for the treatment of women during pregnancy and lactation.

Childhood

The drug is not used to treat children under the age of 6 years.

Best before date

2 years. After the expiration date, the drug should not be used.

Storage conditions

In a dry, dark place at a temperature not exceeding 25 C. Keep out of the reach of children.

Terms of dispensing from pharmacies

Without a doctor's prescription.

Kagocel price

Kagocel tablets 12 mg, 10 pcs., NEARMEDIC Plus, LLC = 188.78 rubles.

Kagocel reviews

Compared with Arbidol, it is somewhat more expensive than 220 rubles for 10 tablets. But as for everything else, the tone is in no way inferior to Arbidol. There are no contraindications, except for allergies. Non-toxic and does not accumulate in the body. It is used for the prevention and treatment of ORS and influenza. They drink it in courses, but as for myself, I drank it when I felt that I was starting to get sick. I drank 2 tablets and the ailment receded. And if you do it right, then it is recommended to take it as follows. Two days, 2 tablets 1 time per day, 5 days off, then repeat the cycle. Reliably protects against flu and colds.

I have already tried Kagocel several times. very satisfied. you really need to read the instructions. daughter had purulent tonsillitis, temperature under 40. took two days, the first day 3 tablets 3 times a day, the second day 2 times a day 2 tablets. squeezed out lemon juice in hot water, drank several times a day. didn't drink anything else. By the evening there was no temperature, and on the second day there were no symptoms of the disease at all. That is, Kagocel fights the virus and side effects such as fever. yesterday I felt very bad, temperature 38.2, chills, weakness. drank the same cogocel and lemon juice with hot water, today she calmly went to work, but she drank Kagocel for the second day. feel great!

A wonderful drug. Last winter, the whole family drank for prevention, no one got sick. A friend drank from herpes, for almost a year she does not remember what kind of infection it is. I recently bought it at a pharmacy, so the pharmacist said that now Kagocel can be taken in children from the age of three. So far, it is not written in the old packages, but she showed the official paper about making changes to the instructions.

Anyone who has had herpes knows what it is discomfort and how it spoils life, and if the sore appears 4 times during the winter, then this is not at all funny. I had it. She began to be treated with Kagocel on the recommendation of a doctor, the wound dries up quickly, burns and itchs less. This winter there was no herpes yet (pah-pah).

The winter period is rightfully the leader in terms of the incidence of infections caused by viruses. During the flu and SARS season, drugstore sales traditionally skyrocket. People in a panic are buying up antiviral drugs and immunomodulators, without even thinking about whether they can be combined with other drugs or alcohol. Most popular means Kagocel is considered to combat various viruses.

Kagocel - what does it affect?

Kagocel is considered the most effective medicine to combat influenza viruses, herpes simplex, as well as their complications. The work of Kagocel is aimed at the production of alpha and beta interferons, which have increased activity for various viruses.

Take Kagocel immediately after suspicious contact with a sick person or according to the scheme described in the instructions. The drug is absolutely non-toxic, can be used in children over 6 years old, but is not recommended during pregnancy.

Alcohol compatibility

Despite the very small presence of contraindications and negative manifestations during treatment, can it be taken with alcohol? controversial issue. The instruction does not give any instructions in this case, but if you understand in detail what exactly Kagocel is, it will become clear why doctors are still very cautious about the drug, and the time when a person takes alcohol.

Firstly, any drugs of the interferon group have a negative effect on mental condition human and they are not compatible with alcohol. Taking Kagocel, especially in people with a history of nervous disorders, may well lead to prolonged depression, excessive anxiety, suspiciousness and even suicide attempts.

Alcohol enhances the effect of the drug, respectively, such neurological symptoms may well appear in a healthy-looking person after drinking alcohol.

Secondly, the action of alcohol blocks the action of interferons in the human body, so the money spent on Kagocel can be considered wasted. In this case, the virus will remain in the body, and the condition of a sick person under the influence of alcohol can only worsen.
Video review of the drug Kagocel:

Possible consequences

Since the drug does not directly interact with alcohol and does not have increased toxicity, it can be said that serious consequences for the body after taking alcohol together with Kagocel should not occur.

However, after such an interaction, unpleasant symptoms are often observed:

• increased fatigue;
• drowsiness during the day and insomnia at night;
• decrease in activity;
• decline in performance and concentration.

Similar neurological symptoms usually not associated with recent alcohol intake during treatment. Fatigue is attributed to a disease suffered not so long ago, irritability to winter blues, and so on. But in fact, this is the detrimental effect of alcohol, coupled with taking an antiviral agent. And if you continue to drink during treatment, then it is quite possible to earn a severe neurological status, and you will have to be treated not only for the flu.

When can you take alcohol

Kagocel is a long-acting drug, its activity remains in the body for four to five days after a single dose.

So take alcoholic drinks can be in five days. But it would be preferable to wait a week before drinking alcohol.

conclusions

As with many other drugs, drinking alcohol together with Kagocel will do more harm than pleasure, this is evidenced by the reviews of all doctors. That is why you should first undergo a course of treatment, get rid of viral activity in your body and already against the background full health you can afford to drink alcohol.

Kagocel is an original domestic antiviral drug belonging to the group of inducers (stimulators) of the synthesis of the immune protein interferon. The role of the active component here is the sodium salt of the copolymer, the length chemical formula which does not allow it to be included in the "Procrustean bed" of this informational article. It is used for the treatment and prevention of influenza and SARS. It has a dual effect: it exhibits direct antiviral activity in combination with a pronounced immunomodulatory effect. Kagocel causes the formation of the so-called. "late" interferons alpha and beta, which are known to be the most effective against viruses. The drug stimulates the production of interferons for a long time: when using a single dose of Kagocel, the therapeutic level of interferons is maintained in the patient's blood for 7 days, which allows it to be effectively used both for the treatment of influenza and SARS, and for their prevention. Along with other drugs of this pharmacological group, kagocel is well combined with immunostimulants, antibacterial drugs, means of chemotherapy. The first clinical studies of kagocel were carried out by scientists from the Research Institute of Influenza (St. Petersburg), the Research Institute of Virology (Moscow) and the Military Medical Academy (St. Petersburg). The study involved about 600 patients with influenza and SARS. For their treatment, the following scheme was used: 2 tablets of Kagocel 3 times a day for the first 2 days, and in the next 2 - 1 tablet 3 times a day. It was found that when using Kagocel in the first 4 days after infection, the drug has a powerful therapeutic effect in influenza provoked by viruses A / H1N1, A / H3N2 and B: a decrease in body temperature in the first 2-3 days was noted by 70% of patients, while as in the placebo group, there were only 25% of such patients. The disappearance of signs of intoxication in the same period was observed in 64% and 20% of patients, respectively. Kagocel is also effective for influenza in combination with bacterial angina: in 90% of patients who received the drug as part of combination therapy, body temperature normalized on days 2-3 and signs of inflammation in the oral cavity and pharynx were eliminated, while in the placebo group, similar changes were observed only in 35% of patients.

The positive effect of Kagocel on the course of other acute respiratory viral infections (adenoviral disease, parainfluenza) is expressed in a reduction in the period of fever, mitigation and complete elimination of signs of intoxication in 85% of patients. According to the results of laboratory and clinical research the drug does not cause negative side reactions, does not have an immunosuppressive effect on tissue and humoral immunity. Thus, Kagocel is a highly effective agent for the prevention and treatment of influenza and SARS caused by various viral strains, incl. pandemic. The drug has a number of advantages compared to other medicines: optimal safety profile, absence of clinically significant adverse reactions, ease of use. It is important that Kagocel has a direct antiviral action, even with a relatively late start of use - 3-4 days from the moment the first signs of infection appear. Kagocel does not accumulate in the body, does not have carcinogenic, teratogenic, embryotoxic and mutagenic properties. In order to prevent the incidence of influenza and SARS, the drug can be used at any time, incl. and as a means of emergency prophylaxis after direct contact with the carrier of the infection.

Kagocel is available in tablets. Adult patients with a therapeutic purpose are prescribed 2 tablets 3 times a day (the first 2 days) and 1 tablet 3 times a day (the next 2 days). Thus, the total duration of the drug course is 4 days. Prevention of viral infections is carried out in seven-day courses: 2 tablets 1 time per day (the first 2 days), after which a 5-day break is made and the course is repeated. Such prophylaxis can be carried out up to several months.

Pharmacology

Antiviral drug, inducer of interferon synthesis. Active substance represents sodium salt copolymer of (1→4)-6-0-carboxymethyl-β-D-glucose, (1→4)-β-D-glucose and (21→24)-2,3,14,15,21,24,29 ,32-octahydroxy-23-(carboxymethoxymethyl)-7,10-dimethyl-4, 13-di(2-propyl)-19,22,26,30,31-pentaoxaheptacyclo dotriaconta-1,3,5(28), 6,8(27), 9(18), 10, 12(17), 13,15-decaene.

It causes the formation in the body of the so-called late interferon, which is a mixture of alpha and beta interferons with high antiviral activity. Kagocel ® causes the production of interferon in almost all cell populations involved in the antiviral response of the body: T- and B-lymphocytes, macrophages, granulocytes, fibroblasts, endothelial cells. When one dose of Kagocel ® is taken orally, the interferon titer in blood serum reaches its maximum values ​​after 48 hours. The dynamics of interferon accumulation in the intestine when the drug is taken orally does not coincide with the dynamics of titers of circulating interferon. In blood serum, the level of interferon reaches high values ​​only 48 hours after taking Kagocel ® , while in the intestines, the maximum production of interferon is noted already after 4 hours.

Kagocel ® when prescribed in therapeutic doses is non-toxic, does not accumulate in the body. The drug does not have mutagenic and teratogenic properties, is not carcinogenic and does not have an embryotoxic effect.

The greatest efficiency in the treatment with Kagocel ® is achieved when it is prescribed no later than the 4th day from the onset of an acute infection. For prophylactic purposes, the drug can be used at any time, incl. and immediately after contact with the infectious agent.

Pharmacokinetics

Suction and distribution

When taken orally, about 20% of the administered dose of the drug enters the general circulation. 24 hours after ingestion, the drug accumulates mainly in the liver, to a lesser extent - in the lungs, thymus, spleen, kidneys, lymph nodes. low concentration noted in adipose tissue, heart, muscles, testicles, brain, blood plasma. Low content in the brain due to high molecular weight drug that makes it difficult to penetrate the BBB. In plasma, the drug is found predominantly in bound form: with lipids - 47%, with proteins - 37%. The unbound portion of the drug is about 16%.

With daily repeated administration of the drug, V d varies widely in all organs studied. The accumulation of the drug in the spleen and lymph nodes is especially pronounced.

breeding

It is excreted mainly through the intestines: 7 days after ingestion, 88% of the administered dose is excreted from the body, including 90% with feces and 10% with urine. The drug was not detected in exhaled air.

Release form

Tablets from cream to brown, round, biconvex, interspersed.

Excipients: potato starch - 10 mg; calcium stearate - 0.65 mg;

10 pieces. - cellular contour packings (1) - packs of cardboard.

Dosage

The drug is taken orally.

Adults for the treatment of influenza and SARS are prescribed in the first 2 days - 2 tab. 3 times / day, in the next 2 days - 1 tab. 3 times / day. In total, for a course lasting 4 days - 18 tab.

Prevention of influenza and SARS is carried out in 7-day cycles: 2 days - 2 tab. 1 time / day, break for 5 days. Then the cycle is repeated. The duration of the prophylactic course varies from 1 week to several months.

For the treatment of herpes, 2 tablets are prescribed. 3 times / day for 5 days. Total for a course lasting 5 days - 30 tab.

Children aged 3 to 6 years for the treatment of influenza and SARS are prescribed in the first 2 days - 1 tab. 2 times / day, in the next 2 days - 1 tab. 1 time / day In total, for a course lasting 4 days - 6 tab.

Children aged 6 years and older for the treatment of influenza and SARS are prescribed in the first 2 days - 1 tab. 3 times / day, in the next 2 days - 1 tab. 2 times / day In total, for a course lasting 4 days - 10 tab.

In children aged 3 years and older, the prevention of influenza and SARS is carried out in 7-day cycles: 2 days - 1 tab. 1 time / day, break for 5 days, then repeat the cycle. The duration of the prophylactic course is from 1 week to several months.

Overdose

Interaction

With the simultaneous use of the drug Kagocel ® with other antiviral drugs, immunomodulators and antibiotics, an additive effect is observed.

Side effects

Possibly: allergic reactions.

The patient should inform the doctor about the development of any side effects.

Indications

• prevention and treatment of influenza and other acute respiratory viral infections in adults and children aged 3 years and older;
• treatment of herpes in adults.

Contraindications

• pregnancy;
• lactation period (breastfeeding);
• children's age up to 3 years;
• lactase deficiency, lactose intolerance, glucose-galactose malabsorption;
• hypersensitivity to the components of the drug.

Application features

Use during pregnancy and lactation

Due to the lack of necessary clinical data, Kagocel ® is not recommended for use during pregnancy and lactation (breastfeeding).

Influence on the ability to drive vehicles and control mechanisms

The effect of the drug on the ability to manage vehicles mechanisms have not been studied.

special instructions

For achievement therapeutic effect taking the drug Kagocel ® should be started no later than 4 days from the onset of the disease.

Kagocel ® is well combined with other antiviral drugs, immunomodulators and antibiotics.

I rarely get colds, although I get a runny nose every time I get cold. I lie in bed and I have a temperature about once a year. So this autumn, a cold overtook me again: on the November holidays I hung out in the square, got caught in the rain and got my feet wet. The result was a runny nose, and then a fever.

Through the long agony of doubt, acquired antiviral drug Kagocel. The manufacturer of which, by the way, is Russian pharmaceutical company. I was surprised when I found out. My treatment stories will be in the recall, let's go!

Kagocel is a Russian drug. in the USA and Western Europe not registered. According to representatives of the Formulary Committee of the Russian Academy of Medical Sciences and OSDM, the effectiveness of the drug has not been proven.

That is why I doubted whether to take the drug again, despite the fact that I already drank it. In general, a lot of negative things about Kagocel can be found on the net, but I did not once again wind myself up with information. All my friends and acquaintances actively advised him as effective drug from a cold and I succumbed to persuasion. The main thing for me it was faster to recover from SARS and get back on my feet. Usually, at the first sign of a disease, I am saved by all sorts of powders, but this time they did not help me.

for sale Kagocel in any pharmacy, the difference is only in price, released without a prescription. I bought in pharmacies "Mint" and "First Aid" (St. Petersburg) for 244 and 248 rubles. Not the cheapest pharmacies, but it was not possible to go to others, as they are far from home. For Kagocel, the price in Ozerki (St. Petersburg) is 212 rubles. This is the cost of one box of 10 tablets.

The course of treatment requires two packages, the monetary equivalent of 500 rubles. My opinion: even if it costs a thousand, the main thing is to heal! Health is not an area in which you need to save.

When I googled quotes for a review, I saw that just a couple of days ago the design of the box had changed. Now it's wider and yellow color(photo below). The following information was found on the net regarding the new packaging:

Now the package has a QR code, which can be read using a smartphone or tablet, get to the official website of the drug and get detailed information about Kagocel.

The new blister is more convenient to use, and the manufacturer has also added Braille information to the packaging. For the thrifty - great news: the shelf life of the antiviral drug Kagocel is now 4 years.

The tablets themselves are just tiny in size! This size will not scare children. A tablet of Kagocel is several times less than fifty and ten kopecks. Color they have beige smell do not have, but taste I didn't feel it when I took it. It probably doesn't exist either. Swallowed without problems, although Kagocel drink water is better just like any other pill.

How to use Kagocel adults and children detailed in the instructions for use. I bring it here in full. To view the image in a larger format, click on it. In red, I highlighted the points about the dosage and method of application. The instruction, unfortunately, has its drawbacks, since it does not indicate to take Kagocel before or after meals and at what time interval. This information came from experience.

For a course of treatment colds (adult) requires 2 packs of 10 tablets, as a result, there are 2 extra pills that are not clear where to go. Kagocel 20 tablets does not exist, which is a pity. It would be nice if they made one pack of 18 or 20 tablets. Kagocel can also be used for prevention, but there will be completely different dosages and costs.

How to take Kagocel for adults with a cold? I drank according to the instructions on the first day, 2 tablets, then one three times a day. Total the course of treatment is 4 days. Very convenient, especially if the drug helps. But he helped me only once, just this year.

my first acquaintance with Kagocel took place in 2016, I caught a cold and had heat. I was treated with Vicks Active powder antipyretic and, in fact, the subject this review. I started treatment on time, I didn’t want to get sick during the holidays. Then I did not notice a pronounced effect from Kagocel. She was completely cured in a week, that is, three days after taking the pills. Vicks helped to remove the temperature. Then I was treated for a cough for another month.

On the November holidays of 2017 (I'm lucky when I get sick when people walk honestly!) My ARVI was less severe, at first my nose was very stuffy. I took AnviMax powder at night. It seemed to feel better in the morning, but also a sore throat.

On the second day, she was treated only with AnviMax. By the evening of the second day appeared subfebrile temperature- 37.2. I really don't like this one, it's hard to knock it down. I took the powder, sweated well. But on the morning of the third day, the temperature remained the same, weakness and dizziness appeared. It was decided to take Kagocel. As they brought it to me, I took 2 tablets at once. Since I did not start drinking the medicine in the morning, I took the pills with an interval of 4 hours. In the evening of the same day, I felt an improvement, drank the powder, sweated and the temperature became normal!

Then I drank Kagocel after breakfast, lunch and dinner one tablet for 3 days. Tablet Feeling gradually improved, the temperature did not return. For the throat, I additionally used Hexoral and Lazolvan cough syrup. Now a day has passed since taking the last pill of Kagocel. Feeling great, no congestion, cough gone. I have never healed so quickly.

I think that Kagocel significantly contributed to my quick recovery for the second time. With belated treatment of ARVI, therefore, it is more effective than with timely. The answer to the main question of the review "Does Kagocel help?": Yes, but not always.

analogues Kagocela Remantadin, Cycloferon and Arbidol are considered. The first one was given to me in childhood by my mother with the flu (it helped), and the second one was taken for the prevention of the herpes virus (Kagocel, by the way, can also be drunk against herpes). In terms of action, Remantadine is a more predictable drug, it has always helped, as far as I remember. Cycloferon is also a means to strengthen the immune system.

Kagocel can be used for prevention colds which should boost the immune system. Do I need an immune booster? My mother, a general practitioner, took a categorically negative position on this issue. Such drugs still will not help to avoid the disease, which means it is a waste of money. I, in turn, believe that if you are engaged in maintaining immunity, then only proven drugs, whose effectiveness has been proven. And this is clearly not Kagocel.

To take or not to take Kagocel question is moot. If they don't help habitual methods treatment, it's worth the risk. If the drug was dangerous, then, I think, it would not be sold everywhere without a doctor's prescription. But the unproven effectiveness of confidence does not inspire, and even repels. Nonetheless, I had no side effects, allergic reactions to the drug. In one of the two cases, Kagocel helped me significantly, so I still recommend it. In cases similar to mine.

Thank you for your feedback, good luck! And if you're already sick, get well soon.