Akriderm: cheap analogues - a list of which is better. Akriderm and its analogues: what to choose for the treatment of skin diseases

pharmachologic effect

A combined drug for external use with anti-inflammatory, antiallergic, antifungal and antibacterial effects.

Gentamicin - antibiotic wide range bactericidal action from the group of aminoglycosides, highly active against gram-negative bacteria Proteus spp. (indole-positive and indole-negative strains), Escherichia coli, Klebsiella spp., Salmonella spp., Shigella spp., Campylobacter spp., Staphylococcus spp. (methicillin-resistant). Active in a relationship Serratia spp., Pseudomonas spp., Acinetobacter spp., Citrobacter spp. To gentamicin resistant: Neisseria meningitidis, Treponema pallidum, anaerobic microorganisms (Streptococcus spp. (except Strepnococcus pneumoniae), Providencia rettgeri).

Betamethasone has anti-inflammatory, antiallergic, antiexudative effects.

Clotrimazole is an antifungal agent from the group of imidazole derivatives. It acts by disrupting the synthesis of ergosterol, which is integral part fungal cell membrane. Has a wide spectrum of action. Active regarding pathogenic dermatophytes (Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum, Microsporum canis), yeast and mold fungi ( Candida albicans, Turolopsis glabrata, Rhodotorula spp., Pityrosporum orbiculare).

Pharmacokinetics

When the drug is used externally in therapeutic doses, transdermal absorption of the active substances into the blood is very insignificant. When applied to the skin, the intensity of absorption of betamethasone depends on the state of the epidermal barrier (inflammation and skin diseases increase absorption).

The use of occlusive dressings increases the transdermal absorption of betamethasone and gentamicin, which may lead to an increased risk of systemic side effects.

Indications

— simple and allergic dermatitis (especially complicated by secondary infection);

— diffuse neurodermatitis (including atopic dermatitis);

— limited neurodermatitis (including simple chronic lichen);

- eczema;

- dermatomycosis (dermatophytosis, candidiasis, pityriasis versicolor), especially when localized in the groin area and large folds of skin.

Dosage regimen

The drug is used externally.

The cream or ointment is applied to the affected areas of the skin without large quantities, lightly rubbing, 2 times/day. The duration of treatment is determined individually and depends on the nosological form and severity of the disease. At tinea pedis average duration treatment is 2-4 weeks.

If clinical improvement does not occur in the near future, it is necessary to clarify the diagnosis or change the treatment regimen.

Side effect

Local reactions: itching, burning sensation, irritation, dry skin, folliculitis, hypertrichosis, steroid acne, hypopigmentation, allergic reactions. When using occlusive dressings - maceration, infection, skin atrophy, stretch marks, prickly heat.

Systemic reactions: at long-term treatment or applied to large surfaces of the skin - weight gain, osteoporosis, increased blood pressure, edema, ulceration of the gastrointestinal mucosa, exacerbation of hidden foci of infection, hyperglycemia, agitation, insomnia, dysmenorrhea.

Contraindications for use

- skin tuberculosis;

- skin manifestations of syphilis;

- chicken pox;

- herpes simplex;

— skin post-vaccination reactions;

- open wounds;

— childhood up to 2 years;

— increased sensitivity to the components of the drug.

WITH caution The drug should be used during pregnancy, especially in the first trimester, in children aged 2 to 18 years.

Use during pregnancy and breastfeeding

During pregnancy (especially in the first trimester), the use of the drug is allowed only in cases where the expected benefit to the mother outweighs the potential risk to the fetus. In such cases, the use of the drug should be short-term and limited to small areas of the skin.

It is not known whether the components of the drug are released from breast milk. Therefore, if it is necessary to use the drug Akriderm ® GK during lactation, breastfeeding should be stopped.

Use in children

The use of the drug in children under 2 years of age is contraindicated.

WITH caution The drug should be used in children aged 2 to 18 years.

Due to the fact that in children the area of ​​skin in relation to body weight is larger than in adults, and the epidermis is underdeveloped, when the drug is used externally, it is possible to absorb a proportionately larger amount of active substances and, therefore, there is a greater risk of developing systemic adverse reactions, as well as atrophic skin changes. The drug should be used in children as much as possible. short term and taking all precautions.

Overdose

Symptoms: with excessive or prolonged use of the drug, symptoms of hypercortisolism may develop.

Treatment: gradual withdrawal of the drug, symptomatic therapy, correction if necessary electrolyte disturbances.

Drug interactions

The interaction of Akriderm GK with other drugs has not been established.

Conditions for dispensing from pharmacies

The drug is approved for use as a means without prescription.

Storage conditions and periods

The drug should be stored out of the reach of children at a temperature of 15° to 25°C. Shelf life – 2 years.

special instructions

Avoid contact of the drug with the eyes.

If resistant bacterial or fungal microflora appears, the drug should be discontinued and appropriate therapy should be prescribed.

Use in pediatrics

Due to the fact that in children the area of ​​skin in relation to body weight is larger than in adults, and the epidermis is underdeveloped, when the drug is used externally, it is possible to absorb a proportionately larger amount of active substances and, therefore, there is a greater risk of developing systemic adverse reactions . The drug should be used in children for the shortest possible time and with all precautions.

Analogues of the drug Akriderm GK are presented, in accordance with medical terminology, called “synonyms” - drugs that are interchangeable in their effects on the body, containing one or more identical active ingredients. When selecting synonyms, consider not only their cost, but also the country of production and the reputation of the manufacturer.

Description of the drug

Gentamicin is a broad-spectrum bactericidal antibiotic from the group of aminoglycosides, highly active against gram-negative bacteria Proteus spp. (indole-positive and indole-negative strains), Escherichia coli, Klebsiella spp., Salmonella spp., Shigella spp., Campylobacter spp., Staphylococcus spp. (methicillin-resistant). Active in a relationship Serratia spp., Pseudomonas spp., Acinetobacter spp., Citrobacter spp. To gentamicin resistant: Neisseria meningitidis, Treponema pallidum, anaerobic microorganisms (Streptococcus spp. (except Streptococcus pneumoniae), Providencia rettgeri).

Betamethasone has anti-inflammatory, antiallergic, antiexudative effects.

Clotrimazole is an antifungal agent from the group of imidazole derivatives. It has an effect by disrupting the synthesis of ergosterol, which is an integral part of the cell membrane of fungi. Has a wide spectrum of action. Active regarding pathogenic dermatophytes (Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum, Microsporum canis), yeast and mold fungi (Candida albicans, Turolopsis glabrata, Rhodotorula spp., Pityrosporum orbiculare).

List of analogues

Note! The list contains synonyms of Akriderm GK, which have a similar composition, so you can choose a replacement yourself, taking into account the form and dose of the medicine prescribed by your doctor. Give preference to manufacturers from the USA, Japan, Western Europe, as well as well-known companies from of Eastern Europe: KRKA, Gedeon Richter, Actavis, Aegis, Lek, Hexal, Teva, Zentiva.

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Official instructions for use

AKRIDERM ® GK

Summary of the drug
Features and Benefits

Registration number:

Tradename drug: Akriderm GK

International generic name or group name:
Betamethasone + Gentamicin + Clotrimazole

Dosage form: cream for external use

Compound
100 g of cream contains:
active substances: betamethasone dipropionate in terms of 100% substance - 0.064 g, clotrimazole in terms of 100% substance - 1 g, gentamicin sulfate in terms of gentamicin - 0.1 g;
Excipients: Vaseline, propylene glycol, liquid paraffin ( Vaseline oil), cetostearyl alcohol [cetyl alcohol 60%, stearyl alcohol 40%]. macrogol cetostsarat (macrogol-20 cetostearyl ether), disodium edetate (trilon B), sodium dihydrogen phosphate dihydrate (sodium phosphate monosubstituted 2-aqueous), purified water.

Description
Cream white or almost white.

Pharmacotherapeutic group: topical glucocorticosteroid + aminoglycoside antibiotic + antifungal agent

ATX code: D07XC01

Pharmacological properties
Pharmacodynamics
The combined drug has anti-inflammatory, antiallergic, antibacterial and antifungal (fungicidal) effects.
Gentamicin is a broad-spectrum antibiotic from the group of aminoglycosides that has a bactericidal effect. Gram-negative microorganisms are highly sensitive - Proteus spp.(indole-positive and indole-negative), Escherichia coli, Klebsiella spp., Salmonella spp.. Shigella spp., Campylobacter spp., Staphylococcus spp.(methicillin-resistant). Sensitive: Enterococcus faecalis, Serratia spp., Pseudomonas spp., Acinetobacter spp., Citrobacter spp. Resistant: Neisseria meningitidis, Treponema pallidum, anaerobic microbes: Streptococcus spp. (except Streptococcus pneumoniae), Enterococcus faecalis; Providcncia rettgeri. Betamethasone is a glucocorticosteroid that has local anti-inflammatory, anti-edematous, and anti-allergic effects.
Clotrimazole is an antifungal agent from the group of imidazole derivatives for topical use. It has an effect by disrupting the synthesis of ergosterol, which is an integral part of the cell membrane of fungi. Has a wide spectrum of action. Active against pathogenic dermatophytes ( Trichophyton rubrum. Trichophyton mentagrophytes, Fpidermophyton floccosum, Microsporum canis, yeast and mold fungi ( Candida spp., Torulopsis glabrata, Rhodotorula spp., Pityrosporum orbicularc).

Pharmacokinetics

Indications for use

Contraindications

Carefully
Pregnancy (especially the first trimester).
Children's age from 2 to 18 years.

Use during pregnancy and lactation
During pregnancy (especially in the first trimester), topical use of the cream in pregnant women is allowed only in cases where the expected benefit to the mother outweighs the potential risk to the fetus. In such cases, the use of the drug should be short-term and limited to small areas of the skin. It is not known whether the components of the drug are excreted in breast milk. Therefore, when prescribing Akriderm GK cream during lactation, it is recommended to stop breastfeeding.

Directions for use and doses

Side effects

Overdose

Interaction with other drugs

special instructions

Release form

Storage conditions

Best before date

Vacation conditions

Manufacturer. Claims are accepted at
Open Joint-Stock Company"Chemical and pharmaceutical plant "AKRIKHIN", 142450, Moscow region, Noginsky district, Staraya Kupavna, Kirova str., 29.

The information on the page was verified by physician-therapist E.I. Vasilyeva.

A course of use of Akriderm GK ointment allows you to get rid of various skin diseases in a short time. Part combination drug contains several active ingredients. They have a complex positive effect on tissues - anti-inflammatory, antimycotic and antimicrobial. The medicine not only relieves a person from discomfort. It effectively eliminates the cause of pathology - fungi and pathogenic bacteria.

Akriderm GK contains a glucocorticosteroid, which, when misuse may provoke adverse reactions. The presence of a hormonal compound in a cream or ointment limits its range of use. Therefore, before starting treatment, you should consult your doctor about the advisability of using the drug.

Akriderm GK is part of an extensive pharmacological group glucocorticosteroids in combinations. All these drugs are prescribed by dermatologists for complex treatment skin pathologies in children and adults. Akriderm GK has proven itself especially well in the treatment of dermatoses of allergic origin.

• antifungal agents;
• antibiotics from various groups;
• non-steroidal anti-inflammatory drugs;
• regeneration stimulants.

This allows you to start treatment without waiting for results laboratory research. If Akriderm GK is prescribed to a small child, then the parents always ask the doctor - this hormonal ointment or not. The drug contains the glucocorticosteroid betamethasone dipropianate. The synthetic hormonal compound exhibits antiexudative and antiedematous activity.

Release form and composition

The drug is produced by the Russian pharmaceutical factory Akrikhin. The primary packaging of Akriderm GK is an aluminum tube, which may contain 15.0 or 30.0 g of the drug. The screw cap has a protrusion for quick and safe opening. The secondary packaging of the drug is a cardboard box with detailed instructions by application.

On pharmacy counters there are two dosage forms of the product for local application, differing in composition:

• Akriderm GK ointment is a transparent gel-like substance with a yellowish tint;
• Akriderm GK cream is a white pasty mass.

The qualitative and quantitative composition of the active ingredients of the ointment and cream is identical.

• glucocorticosteroid betamethasone;
• aminoglycoside group antibiotic gentamicin;
• antifungal agent clotrimazole.

Components for forming the base enhance and prolong the effect of the ingredients. They also provide rapid transdermal and transepidermal penetration of compounds into inflammatory lesions.

pharmachologic effect

Indications for the use of Akriderm GK ointment include pathologies accompanied by acute or chronic inflammation. To suppress it, betamethasone is included in the product. The glucocorticosteroid inhibits the enzyme cyclooxygenase, preventing the production of mediators of pain and inflammation - prostaglandins and bradykinins. It also significantly limits the migration of leukocytes to inflammatory foci. The glucocorticosteroid stabilizes lysosomal membranes and reduces capillary permeability. The antibiotic gentamicin also has an anti-inflammatory effect. It is active against the following pathogens:

• Proteus;
• staphylococci;
• coli;
• streptococci;
• Klebsiella;
• shigella;
• salmonella.

Thanks to the effects of gentamicin, the growth and reproduction of bacteria quickly slows down. The presence of an antibiotic in the ointment or cream allows not only to eliminate the bacterial infection, but also to prevent its occurrence. The antimycotic drug clotrimazole prevents the production of ergosterol by pathogenic yeast-like fungi. They need this connection for construction. cell membranes. Ergosterol deficiency leads to a gradual decrease in the number of fungi on the skin.

Instructions for use

The instructions for use attached to the Akriderm GK package warns that the drug can only be used after visiting a doctor.

Irrational application of hormonal drugs often causes irreversible complications.

Akriderm GK ointment is used to treat diseases in which inflammatory foci are located on the surface of the skin. After its application, a thin film is formed, preventing infection of damaged tissues.

Akriderm GK cream is recommended for use in cases of inflammation that extends to several layers of the epidermis. The cream contains propylene glycol, which ensures deep penetration of active ingredients into infectious foci.

Indications for use

The medication eliminates simple dermatitis. This inflammatory lesion skin, which occurs under the influence of various negative factors.

Akriderm GK is used for the treatment of dermatomycosis and neurodermatitis, often accompanied by a bacterial or mycotic infection.

The cream is often used for lesions pathogenic microorganisms areas located in the folds of the skin. It is prescribed to patients with allergic dermatoses localized to the face and extremities.

• versicolor and herpes zoster;
• eczema, especially of a recurrent nature;
• dyshidrotic dermatitis is a type of eczema that affects the hands and feet;
• ordinary or vulgar ichthyosis.

In some cases, the drug may be included in the therapeutic regimen of patients with candidiasis. A prerequisite for its use is the development of severe inflammation initiated by pathogenic fungi. The drug has proven itself in the treatment of skin diseases of neurogenic origin.

Contraindications and side effects

Efficiency hormonal drug Akriderm GK can be mitigated by a whole group of side effects. It contains a glucocorticosteroid, an antibiotic and an antimycotic, each of which has Negative influence per person. And in combination, the severity and frequency of adverse reactions increase. What you can expect after applying the ointment or cream:

• allergic reaction according to the type of urticaria - rashes, redness, swelling, itching, dryness of the epidermis;
• inflammation of the hair follicles;
• excess body hair growth;
• acne formed under the influence of a hormonal agent;
• prickly heat;
• discoloration of certain areas of the skin;
• formation of stretch marks.

A small amount of glucocorticosteroid and other active components penetrates into the systemic circulation. Despite this, systemic side effects may occur. The most commonly diagnosed disorders are dyspepsia and neurological disorders. A person suffers from nausea, vomiting, excessive gas formation, insomnia, and psycho-emotional instability.

Long-term and irrational use of Akriderm GC causes arterial hypertension And erosive gastritis. There have been cases of weight gain and increased blood glucose levels. The most pronounced side effect of glucocorticosteroids, the thinning of bone tissue, occurs quite rarely.

The main contraindications for Akriderm GK are children under 2 years of age, the period of breastfeeding, otitis externa. Ointment and cream are not used to treat chickenpox, skin tuberculosis, herpes simplex, and syphilitic rashes.

The manufacturer has not carried out clinical trials teratogenic effect of the drug. Therefore, during pregnancy, Akriderm GK is used when the benefit to the mother exceeds the risk to the fetus.

Drug interactions

During the use of Akriderm GK, no cases of interaction with other drugs were identified. But when using it, dermatologists recommend not applying external products with the same ingredients to the skin. Otherwise, the active substances will accumulate in the tissues, which will provoke adverse reactions.

Directions for use and doses

Daily and single dosages, as well as the duration of the therapeutic course, are determined by the attending physician. The instructions for use of Akriderm GK recommend applying the external agent to areas of inflammation 2 times a day.

It is advisable to carry out the procedure at regular intervals to ensure long-term therapeutic effect.

Before applying the product, the skin must be treated antiseptic solutions and pat dry with a towel. The drug is characterized by side effects allergic actions, so the ointment should be rubbed into a small area of ​​skin. Treatment is carried out in the absence of redness and rashes after half an hour. Akriderm GK can be used in two ways:

• distribute evenly thin layer onto the surface of the skin and allow it to be absorbed;
• Apply the ointment to a sterile napkin and apply to the damaged area. Secure the bandage with a narrow bandage or a strip of adhesive tape.

Since the product for external use contains a glucocorticosteroid, it should be used with caution in the treatment of children. Dosages for them are determined by the doctor based on the severity of the disease. U small child high permeability of blood vessels, so more ingredients will penetrate into the systemic circulation. When applying the ointment to a large surface of the skin, systemic side effects may occur.

The use of the drug is discontinued if adverse reactions develop or if it fails within 10-14 days. In these cases, you need to consult a dermatologist. He will adjust the dosage or replace the drug similar action, but with a different composition.

Storage conditions and periods

Akriderm GK cream and ointment should be stored in a cool place (temperature 15-25°C), protected from sun rays place. Aluminum tubes should not be kept in the refrigerator. The medicine should be out of reach of small children. The shelf life of the drug is 24 months.

Please note that immediately after opening the primary packaging, the shelf life of Akriderm GK ointment and cream is reduced to 2-3 months.

Terms of sale

Akriderm GK is a prescription drug. Before purchasing, you must provide the pharmacist with a doctor's note with the name and dosage of the drug. It's not only necessary condition sales, but also a way to avoid mistakes. The fact is that the manufacturer produces the Akriderm therapeutic line, which includes about ten drugs.

A hormonal product for local application is relatively inexpensive. Here is the average price in pharmacies:

• Akriderm GK cream 15.0 g - 390 rubles;
• Akriderm GK ointment 15.0 g - 400 rubles;
• Akriderm GK cream 30.0 - 630 rubles;
• ointment Akriderm GK 30.0 - 620 rubles.

Analogues of Akriderm GK are not yet produced at a cheaper price. Only imported drugs with approximately the same composition are on sale. But their cost is much higher.

Ointment or cream may be prescribed by your doctor for long-term treatment or for application to large areas of the skin. In such cases, it is better to purchase large packaging. This can save you a significant amount of money. In addition, you won’t have to waste time on another visit to the pharmacy.

Akriderm's analogs

Structural analogue of ointment or cream - imported drug. It is with this that you can safely replace Akriderm GK, but it costs much more. Triderm contains the same active ingredients and in identical concentrations.

The following anti-inflammatory ointment analogues are available on pharmacy counters:

• Belosalik;
• Beloderm;
• Celestoderm.
• Uniderm.

Article rating

Akriderm is a medicine for skin diseases for external use. His pharmachologic effect is aimed at suppressing the increase in the number of leukocytes, inhibiting phagocytosis, reducing tissue vascular permeability, and preventing the appearance of inflammatory edema.

Akriderm Genta or Akriderm GK differ in composition. Both medications contain betamethasone dipropionate, but in addition to it, Genta includes gentamicin sulfate, and GK - gentamicin and clotrimazole. Betamethasone dipropinate, which includes some analogues of Akriderm, performs anti-inflammatory, anti-edematous and anti-allergic functions.

Akriderm's analogs

All analogues of Akriderm are drugs for the treatment inflammatory processes, swelling, allergic reactions or dermatitis of different nature origin. To understand how you can replace Akriderm ointment and not harm your health, it is recommended to undergo examination by a doctor.

Taking into account all the characteristics of the body, it will help determine the most suitable remedy and based on prices, if there are limitations on possible costs, will help you choose the optimal and effective option. Next, we will consider analogues that have proven themselves to be one of the most effective, and at the same time inexpensive.

Beloderm

Beloderm is cheap analogue Akriderm ointment. In the first moments of applying the cream to the skin, the medicine actively fights pain, swelling, erythema and irritation.

In what cases should Beloderm be used?

1. Psoriasis.
2. Various manifestations of eczema.
3. Allergic dermatitis.
4. For skin irritations after an insect bite.
5. Lichen planus (red).
6. Radiation dermatitis.
7. Neurodermatitis.
8. Solar dermatitis.
9. Exudative erythema multiforme.

The drug is also effective in combating itchy sensations that have different shapes origin and in the presence of contact dermatitis.

Contraindications:

• skin lesions by fungus, bacteria or viruses;
• trophic ulcer;
• chicken pox;
• skin signs of syphilis;
• various skin tumors;
• cutaneous tuberculosis;
• rosacea;
• post-vaccination reactions;
• acne vulgaris.

Important! This analogue of Akriderm cream is not recommended for use by people suffering from hypersensitivity to the components of the drug. For pregnant women and children under 6 months of age, Beloderm is prescribed exclusively by a doctor, with extreme caution.

Celestoderm B

Celestoderm B is an anti-inflammatory drug with a pronounced variconstrictor effect. The price of the medicine is slightly higher than the cost of Akriderm itself, by about 100-120 rubles.

What side effects might there be?

The occurrence of side effects can be caused by the use of an occlusive dressing. If deviations occur, they can manifest themselves in the form of folliculitis, itching sensations, hypertrichosis, secondary infection, acne-like rash, contact or allergic dermatitis.

In what cases should Celestoderm B not be taken?

The medicine is prohibited for use if the patient is sensitive to the components of the medicine and in the presence of the following deviations:

• common herpes;
• cutaneous tuberculosis;
• chicken pox;
• signs of syphilis on the skin;
• cracks in the skin;

Note! Celestoderm B is not taken by women during breastfeeding and gestation. Also, the medicine should not be used by children if they are under 6 years of age.

Analogues of Akriderm Genta

Akriderm Genta is different in that, in addition to betamethasone, it contains gentamicin sulfate, an antibiotic of the aminoglycoside group, which has a wide spectrum of action. Analogs of Akriderm Genta and the drug itself are used for treatment various forms dermatitis and eczema.

Betaderm

Betaderma contains gentamicin and betamethasone. Before prescribing it, doctors immediately draw the patient’s attention to the fact that the medicine should under no circumstances get into the eyes. And if any deviations occur during the treatment process, use of Betaderm should be stopped immediately.

Contraindications

Betaderm is prohibited for patients suffering from the following disorders:

1. Lupus.
2. Simple herpes.
3. Chicken pox.
4. Syphilis, which manifested itself through skin abnormalities.
5. Vaccination;
6. Post-vaccination reactions.

Like many Akriderm analogues, Betaderm is prohibited for use by women during breastfeeding.

For what diseases is Betaderm most effective?

Since Betaderm has similar properties to Akriderm ointments, it also actively helps the patient in the fight against:

• allergic or common dermatitis (in particular those accompanied by secondary infection);
• chronic lichen simplex;
• eczema, senile itching;
• atopic dermatitis;
• diaper rash, lichen planus;
• psoriasis;
• dyshidrosis;
• erythroderma;
• exfoliative and solar dermatitis.

Candide B

Candide B comes in cream form. The active ingredients of the product are beclomethasone and clotrimazole. Before applying it to problem areas of the skin, they must first be washed and dried, then apply the cream in a thin layer and rub in lightly. The procedure must be repeated 2-3 times a day.

Who is Candide B contraindicated for?

The medicine is not used by people with cutaneous tuberculosis, herpes simplex, or if the patient is sick chicken pox, measles, suffers from skin post-vaccination reaction, skin manifestations syphilis and dermatosis, which arose as a result of complications of smallpox vaccination or if the patient has increased sensitivity to the components of the cream.

Women are prohibited from using the medicine during lactation.

In what cases should it be used?

1. Fungal skin infection.
2. Dermatomycosis.
3. Dermatosis.
4. Athlete's foot.

As adverse reactions, the cream can provoke skin hyperemia, stitching sensations, allergies to components, and when using an occlusive dressing - folliculitis, pyoderma or rash.

Analogues of Akriderm SK

The active ingredients of Akriderm SK were salicylic acid, as well as betamethasone, which is characteristic of all drugs in this group. The medicine is mainly used to treat chronic and subacute forms of dermatitis.

Akriderm SK ointment can also be prescribed to patients with ichthyosis or patients suffering from ichthyosoform abnormalities. Next, we will consider two analogues of Akriderm SK, which were able to adequately replace it and showed maximum effectiveness.

Belosalik

Belosalik - is available in the form of a solution or ointment, both forms are positioned as Akriderm SK analogues. You can buy it cheaper by about 70-100 rubles, depending on the number of grams.

Indications for use

The diseases that Belosalik actively fights include:

• verrucous verrucous;
• eczema;
• psoriasis;
• ichthyosis disease;
• the presence of lichen planus;
• seborrheic dermatitis hairline heads;
• hives;
• keratosis (palmoplantar);
• seborrhea;
• neurodermatitis;
• chronic discoid lupus (erythematosus);
• pathological dry skin.

Who is Belosalik contraindicated for?

The medicine should not be used if a person suffers from:

• chicken pox;
• acne vulgaris;
• trophic ulcers;
• skin lesions from viruses;
• fungal skin diseases;
• post-vaccination reactions;
• bacterial skin diseases;
• perioral dermatitis;
• skin cancer;
• nevus;
• hemangiomas;
• xanthomas;
• atheromas;
• epitheliomas;
• sarcomas;
• melanoma.

Important! The drug in the form of an ointment is prohibited for treatment by children if they are not yet 1 year old, as well as by pregnant women and mothers during breastfeeding. If the use of medication during lactation is necessary, it is carried out under the strict supervision of a physician. It is strictly forbidden to apply ointment to the breasts before feeding.

Diprosalik

Akriderm SK can be replaced with another analogue - Diprosalik. It refers to combined means and acts with the help of an antiseptic and corticosteroids. It is used for treatment dermatological diseases and is quite expensive, its price in online pharmacies ranges from 535 to 550 rubles.

For what diseases should Diprosalic be used?

The analogue copes well with diseases such as eczema, common ichthyosis, psoriasis, dyshidrosis (a skin disease characterized by the appearance of transparent blisters on the feet and hands), lichen planus (numerous skin rashes), seborrheic dermatitis and chronic atonic dermatitis.

Who should not use Diprosalic?

Doctors note that the drug should not be used by patients suffering from tuberculosis, fungal skin infections, or if a person may have allergic reactions to the components of the drug.

During lactation and pregnancy, it is better for women not to use Diprosalik, since its effect on the fetus and milk during breastfeeding has not yet been fully studied, so the risk is not justified.

Analogues of Akriderm GK

Akriderm GK is produced in the form of a whitish, almost transparent ointment. Most often, Akriderm GK ointment is prescribed for eczema, diffuse neurodermatitis, ringworm and limited types of neurodermatitis.

In the form of analogues of Akriderm GC it is customary to use cheap drugs Kanzinon and Triderm.

Kanzinon

The drug Kanzinon is a synthetic antifungal agent that belongs to the group of imidazole derivatives. Like many cheap analogues, it can be purchased for only 60-80 rubles. While Akriderm GK cream costs about 570 rubles.

Canzinon, in addition to cream or ointment, can be produced in the form vaginal cream or pills for women.

What diseases can Kanzinon treat?

Kanzinon in the form of Akriderm GC analogue copes with diseases such as:

1. Stomatitis.
2. Interdigital fungal infection.
3. Urethritis and other genital infections.
4. Versicolor and pityriasis versicolor.
5. Fungal paronychia.

Who is Kanzinon contraindicated for?

Based on the data from the instructions, we can conclude that Canzinon is strictly forbidden to be used by children under 2 years of age, women during menstruation and in the first trimester of pregnancy.

With extreme caution, doctors may prescribe the medicine to children under 12 years of age, women during lactation, and patients with abnormal liver function.

It is important to know! The medicine may cause side effects in the form of headache, dizziness, pain in the genitals, frequent urination, swelling of the mucous membrane and painful discharge, if the drug was used intravaginally.

Triderm

Like the rest of Akriderm GK, this is a medicine for external application to the skin. It is used exclusively for the treatment of diseases that a person acquired through infectious secondary means. The drug is not used for prophylactic purposes. All because active action substances included in its composition.

The medicine is produced in the form of a cream or ointment. For the price they do not have big difference, the cream will cost about 50-60 rubles lower than the ointment, full price funds do not exceed 710 rubles.

Indications

Triderm has shown maximum effectiveness in the fight against the following diseases:

• atopic and allergic dermatitis;
• chronic lichen;
• candidiasis;
• dermatophytes;
• pityriasis versicolor;
• various forms of eczema;
• limited neurodermatitis.

Who is contraindicated for using Triderm?

The drug should not be used by people suffering from the following diseases:

1. Complications of chickenpox.
2. Cutaneous tuberculosis;
3. At open wounds Oh;
4. Consequences of skin vaccinations;
5. Herpes.
6. Syphilis manifestations on the skin

The doctor will not prescribe Triderm to a child under 2 years of age or to a person who is sensitive to the components of the drug.

Important observation! The medicine should be stopped gradually. To begin with, use it no more than once a day, then you can reduce the amount and apply the cream every other day, then once a week, and only then stop using it.

Conclusion

All analogues of Akriderm GK or other types of cream must be accompanied by confirmation from a doctor. Only then, taking into account all the contraindications and characteristics of the body, can you safely begin to treat skin diseases.

Thank you

Group of drugs for external use Akriderm as the main active substance contains glucocorticosteroid hormone betamethasone, which has powerful anti-inflammatory and antiallergic effects. Therefore, Akriderm ointments and creams are effective for stopping any severe inflammatory processes on the skin. Accordingly, Akriderm is used in the treatment of acute, chronic and subacute skin diseases, which are based on the inflammatory process (dermatoses).

Names, varieties, release forms and composition of Akriderm

Currently, four varieties of Akriderm are produced, such as:

• Akriderm - ointment and cream;
• Akriderm Genta – ointment and cream;
• Akriderm GK – ointment and cream;
• Akriderm SK – ointment.

Akriderm ointment and cream The active components contain only betamethasone, a glucocorticoid hormone. Moreover, the ointment is available in only one concentration - 0.05%, and the cream - in two: 0.064% and 0.05%.

Ointment and cream Akriderm Genta have exactly the same composition and concentration of active components, such as: betamethasone - 0.64 mg per 1 g and gentamicin - 1 mg per 1 g. That is, Akriderm Genta ointments and creams contain the glucocorticoid hormone betamethasone and the antibiotic gentamicin as active components . The concentration of ointment and cream is determined by the content of betamethasone and is, respectively, 0.064%.

Ointment and cream Akriderm GK also have exactly the same composition and concentration of active components. Thus, the composition of Akriderm GK creams and ointments includes the following as active ingredients:

• betamethasone – 0.64 mg per 1 g;
• gentamicin – 1 mg per 1 g;
• clotrimazole – 10 mg per 1 dose.

Akriderm SK ointment as active ingredients it contains betamethasone 0.064 mg per 1 g and salicylic acid 30 mg per 1 g. That is, Akriderm SK ointment contains betamethasone and a keratolytic salicylic acid. The concentration of the ointment is traditionally indicated by the amount of betamethasone and, accordingly, is equal to 0.064%.

Cream ointments of each type of Akriderm differ from each other only in the composition of auxiliary components and physical properties(consistency, thickness, fat content, etc.). Accordingly, ointments and creams are intended for application to skin affected by the same diseases, but in different states.

What is Akriderm used for (therapeutic effect)?

Betamethasone, which is part of all varieties of Akriderm, is a glucocorticoid hormone that has the following therapeutic effects:

• Anti-inflammatory;
• Antiallergic;
• Antiexudative;
• Decongestant;
• Antipruritic.

Akriderm should be used in short courses, which are necessary to eliminate severe inflammation, swelling and itching, as well as to stop a dangerous allergic reaction. After inflammation and allergies are significantly reduced under the influence of Akriderm, it is necessary to stop using it and switch to using other means necessary to completely cure the existing disease. That is, Akriderm ointment and cream are a kind of drugs emergency assistance in difficult situations.

Gentamicin, which is part of the Akriderm Genta variety together with betamethasone, is a broad-spectrum antibiotic that is destructive against various bacteria. This means that Akriderm Genta, in addition to the indicated effects of betamethasone, additionally has an antibacterial effect, destroying pathogenic bacteria that provoke infectious and inflammatory processes on the skin. Therefore, Akriderm Genta ointment and cream are intended to relieve severe inflammatory processes and allergic reactions complicated by the addition of bacterial infection(pustules, pimples, etc.).

Salicylic acid, which is part of Akriderm SK in combination with betamethasone, is a keratolytic, that is, it helps exfoliate dead cells of the upper layer of the epidermis. Since many skin diseases are accompanied by hyperkeratosis, that is, its thickening and roughening, the use of a keratolytic that can remove excess dead keratinized cells can eliminate this state. Accordingly, Akriderm SK ointment has powerful anti-inflammatory and antiallergic effects provided by betamethasone, and in addition to them, keratolytic. Thus, Akriderm SK is optimal for use in cases of severe inflammation or allergies in areas of the skin with hyperkeratosis.

To summarize, we can briefly indicate why each type of Akriderm is needed:

• Akriderm – severe inflammation or an allergic reaction to the skin;
• Akriderm Genta - severe inflammation or allergic reaction to the skin in combination with a bacterial infection;
• Akriderm GK – severe inflammation or allergic reaction to the skin in combination with a fungal infection;
• Akriderm SK - severe inflammation or allergic reaction in areas of the skin with hyperkeratosis.

Indications for use

Akriderm ointment and cream

• Contact dermatitis with any course (acute, subacute, chronic);
• Occupational dermatitis;
• Seborrheic dermatitis;
• Drug dermatitis;
• Atopic dermatitis (diffuse neurodermatitis);
• Solar dermatitis;
• Dyshidrotic dermatitis;
• Toxic dermatitis;
• Contact dermatitis;
• Intertrigo;
• Photodermatitis;
• Intertriginous dermatitis;
• Neurodermatitis;
• Skin itching;
• Eczema.

• Exfoliative dermatitis;
• Radiation dermatitis;
• Simple chronic lichen (limited neurodermatitis);
• Hyde's pruritus;
• Prurigo;
• Gluteal dermatitis.

Ointment and cream Akriderm Genta

• Simple dermatitis;
• Allergic dermatitis;
• Eczema;
• Solar dermatitis;
• Exfoliative dermatitis;
• Radiation dermatitis;
• Diaper rash;
• Itchy skin with infected scratches and wounds.

Ointment and cream Akriderm GK

• Pemphigus;
• Lyell's syndrome;
• Psoriasis;
• Duhring's disease;
• Blistering dermatitis;
• Contact dermatitis;
• Toxidermy.

Akriderm SK ointment

• Psoriasis;
• Simple chronic lichen (limited neurodermatitis);
• Atopic dermatitis (diffuse neurodermatitis);
• Lichen planus;
• Eczema;
• Dyshidrotic dermatitis;
• Ichthyosoform changes.

Akriderm - instructions for use

What to use, ointment or cream - rules for choosing the dosage form and variety of Akriderm?

Having chosen the required variety of Akriderm, you need to decide which dosage form - cream or ointment - is best to use in this particular case. Thus, creams of any variety of Akriderm are recommended for application to damp and wet surfaces skin, for example, on wounds with copious discharge, etc. Ointments of any type of Akriderm are optimal for application to dry skin with scales and peeling. Of course, if necessary, if it is not possible to purchase the optimal form of Akriderm (ointment or cream), you can replace the cream with ointment and vice versa. However, it is better to follow the recommendations and use cream for wet skin, and ointment for dry skin.

Akriderm, Akriderm Genta, Akriderm GK and Akriderm SK - instructions for use

So, a thin layer of ointment or cream is applied to the affected area of ​​the skin 2–6 times a day. The ointment or cream is gently rubbed into the skin with light massaging movements, after which it is left for several minutes for complete absorption. To enhance the therapeutic effect, a tight or occlusive bandage can be applied over the ointment or cream and left until the next application of the drug. If a large area of ​​skin is being treated (more than 10 cm X 10 cm), then occlusive or tight dressings cannot be applied, since this increases the risk of absorption of a large amount of cream or ointment into the blood and the occurrence of systemic side effects of glucocorticoids.

A tight bandage consists of applying a sterile napkin to an area of ​​skin treated with Akriderm ointment or cream, which is wrapped with a sterile bandage. For an occlusive dressing, a piece of polyethylene or other moisture- and air-tight material (for example, rubber, etc.) must be placed on top of the cream or ointment. This piece of air- and moisture-proof material is fixed with a tight bandage made of a sterile bandage.

In the vast majority of cases, applying ointment or cream to the skin twice (morning and evening) is enough to achieve a good therapeutic effect. However, if the inflammation is very severe and the morning application of cream or ointment is not enough to ensure a therapeutic effect until the evening, then the drugs can be used up to 6 times a day. In addition, more than twice a day it is recommended to apply Akriderm creams or ointments to those areas of the skin from which they quickly wear off, for example, on the feet, fingers and toes, etc. If the disease is mild, then ointment or cream of any type of Akriderm can be applied only once a day, in the morning.

The duration of treatment with ointments or creams of any type of Akriderm is on average 2 – 4 weeks. The drugs can be used for less than two weeks if the result was achieved faster. That is, any type of Akriderm can be used until the required clinical effect is achieved (for example, complete suppression of inflammation and itching, etc.), but no longer than 4 weeks. However, when applying Akriderm to the face, the duration of therapy should not exceed five days.

If, after 2 weeks of continuous use of any type of Akriderm, clinical improvement has not occurred, you should consult a doctor for additional examination, clarification of the diagnosis and prescription of other treatment.

Akriderm ointments and creams should not be used for longer than 4 weeks, as this can cause addiction and withdrawal symptoms due to the presence of glucocorticoid hormone in the preparations. When using Akriderm for longer than 3 weeks, the drug should be discontinued gradually. To do this, it is recommended to first halve the amount of cream or ointment applied to the skin for two days, leaving the same frequency of application (for example, 2, 3 times a day). Then, on the third day, one application of cream or ointment to the skin is canceled. After another two days, the amount of cream or ointment used for application is again halved. After another two days, cancel one application of the product to the skin, etc.

If, after using ointments and creams of any type of Akriderm, side effects or signs of irritation on the skin appear, then you must stop using the drug and consult a doctor to select another medicine necessary to treat the existing problem.

When using Akriderm ointments and creams for a long period of time or when applying them to large areas(more than 10 cm X 10 cm), betamethasone can be absorbed into the bloodstream in relatively high dosages, which ensure the appearance of systemic effects of glucocorticoids. That is, if you use Akriderm for a long time or apply it to large areas of the skin, then a person will experience the same effects of betamethasone as if he took it orally in the form of tablets or injected it (intravenously or intramuscularly). In addition, when using Akriderm Genta and Akriderm GK for a long time or over large areas of skin, not only betamethasone, but also gentamicin or clotrimazole, respectively, can be absorbed into the blood, which also provokes the development of systemic side effects of this antibiotic and antifungal agent. In the case of Akriderm Genta, the most severe systemic side effect of gentamicin absorbed into the bloodstream is hearing impairment.

In young children over one year of age, any type of Akriderm should be used only if indicated, under medical supervision and for the shortest possible time, since they have a very high risk of developing systemic glucocorticoid effects due to the absorption of betamethasone in a high dosage relative to the child’s body weight. In addition, in children under 7 years of age, when using any type of Akriderm, tight or occlusive dressings should not be used, as this will increase the absorption of betamethasone into the blood and significantly increase the risk of developing systemic side effects of glucocorticoids, such as suppression of the hypothalamic-pituitary-adrenal axis with the formation of hypercortisolism, as well as increased intracranial pressure and decreased production of growth hormone.

Creams and ointments of any type of Akriderm cannot be used in ophthalmological practice, therefore, when using them, it is necessary to avoid getting the compositions into the eyes. If ointment or cream accidentally gets into your eyes, they should be rinsed big amount clean running water and consult a doctor. In addition, it should be remembered that when applying Akriderm creams and ointments to areas with thin skin, for example, in the area around the anus, armpits and in the groin fold, stretch marks (stretch marks) may form. Therefore, in these areas it is recommended to use Akriderm for the shortest possible period.

Akriderm creams and ointments should not be used to treat trophic leg ulcers, open wounds and varicose veins. When using ointments and creams of any type of Akriderm, it is recommended to refuse preventive scheduled and emergency vaccinations.

Use during pregnancy and breastfeeding

Since it is unknown whether betamethasone and other active components of Akriderm varieties penetrate into milk, during the period of use of the drugs you should stop breastfeeding the baby and switch him to artificial formula.

Impact on the ability to operate machinery

Overdose

• Hyperglycemia (increased blood glucose levels);
• Glucosuria (appearance of glucose in the urine);
• Cushing's syndrome (weight gain, fat deposition on the face and abdomen, etc.);
• Increased blood pressure;
• Edema.

Interaction with other drugs

Side effects of Akriderm

So, betamethasone in all forms of Akriderm has the following side effects:

• Burning sensation on the skin;
• Skin irritation;
• Dry skin;
• Hypertrichosis (excessive body hair growth);
• Acne-like rashes;
• Hypopigmentation (patches of lighter colored skin);
• Perioral dermatitis;
• Pyoderma (pustular skin lesions);
• Skin maceration;
• Skin atrophy;
• Erythema (redness of the skin);
• Purpura;
• Striae (stretch marks);
• Telangiectasia (spider veins);
• Secondary skin infection;

• Hyperglycemia (increased blood glucose levels);
• Glucosuria (sugar in urine);
• Ulceration of the mucous membrane of the digestive tract;
• Weight gain;
• Increased blood pressure;
• Edema;
• Exacerbation of latent chronic infections;
• Excitation;
• Menstrual irregularities;
• Paresthesia (sensitivity disturbances such as numbness of the extremities, sensation of “pins and needles”, etc.);
• Hypokalemia (decreased potassium concentration in the blood);
• Delayed growth and weight gain (for children only);
• Promotion intracranial pressure– typical for children (bulging