Ascorbic acid instructions for use of tablets for children. How to take ascorbic acid tablets

All mothers know about the benefits of vitamin C, so its intake in children's body attention is paid from birth, creating a rational menu for the baby. If you provide the child sufficient quantity ascorbic acid If it doesn’t work out with food, they resort to vitamin supplements. From what age is it permissible to give pharmaceutical drugs with vitamin C to prevent its deficiency and for what diseases they are needed childhood?

Release form

Ascorbic acid is produced:

• In tablets. These round tablets may be white, pink, orange or another color depending on the composition. They include 25 mg or 100 mg of ascorbic acid, but also produce a preparation with 50 mg, 75 mg, 300 mg or 500 mg of this vitamin compound. One pack contains 10, 50 or 100 tablets.
• In jelly beans. Often these are small spherical vitamins yellow color. Each tablet contains 50 mg of vitamin. One package contains 50, 100, 150 or 200 tablets.
• In ampoules. This form of ascorbic acid is intended for injection into a vein or intramuscular injections. This is a 5% or 10% transparent solution, bottled in 1 or 2 ml ampoules. One package includes 5 or 10 ampoules.
• In powder. A solution is prepared from it, which must be taken orally. The powder is colorless or white crystals that have no odor. It is packaged in bags of 1 or 2.5 g. One pack contains from 5 to 100 such bags.

Ascorbic acid is available in various flavoring additives and the kids really like it

Compound

The powder form contains only ascorbic acid. In addition to the main substance, tablets and dragees may contain sucrose, wax, calcium stearate, dye, dextrose, starch, lactose, talc, crospovidone and other auxiliary ingredients. In addition to vitamin C, the injection form may contain water, sodium sulfite and bicarbonate, cysteine, and disodium edetate.

Operating principle

Once in the body, ascorbic acid has the following effect:

• Normalizes the permeability of small vessels.
• Protects cells and tissues from toxic substances(antioxidant effect).
• Strengthens protective forces, preventing viral infections and colds due to activation of the formation of antibodies and interferon.
• Helps absorb glucose.
• Has a positive effect on liver functions.
• Regulates blood clotting.
• Accelerates skin healing in case of damage.
• Participates in the formation of collagen.
• Helps absorb iron and folic acid.
• Activates digestive enzymes, improves bile secretion, pancreas and thyroid function.
• Reduces the manifestations of allergies and inflammation by inhibiting the formation of mediators involved in these pathological processes.

How vitamin C affects the body and what are the indications and contraindications for the use of ascorbic acid - watch in a short video:

Indications

• If his diet is unbalanced and there is a risk of hypovitaminosis.
• During the active growth of the child's body.
• To prevent ARVI. This reason is relevant in autumn, during winter cold and early spring.
• If the child has increased emotional or physical stress.
• If your baby is recovering from injury or surgery.

WITH therapeutic purpose Vitamin C preparations are prescribed:

• With diagnosed hypovitaminosis C.
• With hemorrhagic diathesis.
• For nosebleeds and other bleeding.
• For infectious diseases or intoxications.
• With excessive use of iron supplements for a long time.
• For acute radiation sickness.
• For anemia.
• For liver pathologies.
• For colitis, peptic ulcer, enteritis or achylia.
• For cholecystitis.
• With sluggish healing of burns, ulcers or wounds on the skin.
• For bone fractures.
• With dystrophy.
• For helminthiasis.
• For chronic dermatoses and some other skin diseases.

At what age can it be given?

Give medications with ascorbic acid one year old child it is forbidden. Tablets containing 25 mg of ascorbic acid are prescribed from 3 years of age. Dragees containing the vitamin in a dose of 50 mg are prescribed for children over 5 years of age.

Such age restrictions are associated with difficulties in swallowing the drug in early age, as well as the risk of inhaling the pills. If necessary, your doctor can prescribe vitamin C earlier, but you should not do this on your own. Even when the child is already 3 years old or older, you should consult your pediatrician about the use of such a vitamin.

Contraindications

Instructions for use prohibit ascorbic acid in the following cases:

• If the patient has an intolerance to such a vitamin.
• If there is a tendency to thrombosis or thrombophlebitis is detected.
• If the child has diabetes (for forms with sugar).
• If the blood test showed too high level hemoglobin.
• If a young patient is diagnosed with severe renal pathology.

A child under one year old cannot take vitamin C in the form of tablets and dragees.

Side effects

Sometimes a child’s body reacts to taking ascorbic acid with an allergy. These are often skin changes that manifest themselves as redness, itching, and rashes.

Treatment with vitamin C may also lead to:

• Thrombocytosis, erythropenia, leukocytosis due to neutrophils.
• Weakness and dizziness (if injected into a vein too quickly).
• Diarrhea (at high dosage).
• Nausea or vomiting.
• Damage to tooth enamel (with prolonged absorption in the mouth).
• Fluid and sodium retention.
• Education in urinary tract oxalate stones (with long-term use high doses).
• Disruption of metabolic processes.
• Kidney damage.
• Pain at the injection site (if administered intramuscularly).

Sometimes children develop an allergy to vitamin C, which manifests itself as a rash on the various parts body

Instructions for use and dosage

• Ascorbic acid tablets with glucose or dragees are offered to the child after meal.
• Prophylactic dose for children 3-10 years old it is represented by 1 tablet containing 25 mg of vitamin, and over the age of ten years this daily dosage is increased to two tablets (50 mg per day).
• Treatment dose is 2 tablets of 25 mg of ascorbic acid per day up to the age of 10 years ( daily dose 50 mg) and three to four tablets of the drug over the age of 10 years (daily dosage 75-100 mg).
• It is recommended to take ascorbic acid prophylactically from two weeks to two months. The duration of the treatment course is determined by the doctor.
• If the dosage of the active substance in a tablet is 100 mg, then this ascorbic acid is given in a dose of 1/2 tablet per day to children over 6 years of age.
• Dragees are given for prevention to children over five years old, 1 piece per day, and for treatment - 1-2 dragees up to 3 times a day.
• Only a doctor should prescribe Ascorbic acid in injections to children. The daily dosage is 1-2 ml of the drug, but a more precise dose, route of administration and duration of therapy should be determined by a specialist, taking into account the disease in a particular child.

Overdose

Since ascorbic acid is a water-soluble compound, hypervitaminosis does not develop with an excessive dosage of this vitamin. However, excessively high doses of such a substance can damage the mucous membrane of the stomach and intestines, which leads to abdominal pain, diarrhea, bloating, vomiting and other negative symptoms.

Also poisoning is very big amount Vitamin C deficiency is manifested by weakness, sweating, hot flashes, insomnia, and headaches. In addition, an excess of this substance will reduce capillary permeability, which will impair tissue nutrition, increase blood pressure and can lead to hypercoagulation.

To prevent ascorbic acid from causing illness, you should be aware of the maximum recommended dosages of this vitamin:

• For children under 3 years old this is 400 mg per day.
• For a child aged 4 to 8 years maximum dose per day is called 600 mg.
• For children 9 to 13 years of age, dosage should not exceed 1200 mg per day.
• At the age of over 14 years, the permissible maximum ascorbic acid per day is 1800 mg of this vitamin.

Watch an educational video that explains what can happen if you allow excess vitamin C in the body:

Interaction with other drugs

• The use of ascorbic acid will increase the blood levels of penicillin and tetracycline antibiotics, as well as salicylates.
• When taking vitamin C and acetylsalicylic acid together, the absorption of ascorbic acid worsens. The same effect is observed if you drink ascorbic acid with an alkaline liquid or fresh juice.
• Simultaneous use with anticoagulants will reduce their therapeutic effect.
• Taking vitamin C together with iron supplements promotes better absorption of Fe in the intestines. If you prescribe ascorbic acid and deferoxamine, iron toxicity will increase, which will negatively affect the heart and its function.
• It is not recommended to mix the injection form of vitamin C in the same syringe with any medications, since many drugs react chemically with ascorbic acid.
• With simultaneous treatment with barbiturates, the excretion of ascorbic acid in the urine increases.

Terms of sale

You do not need a prescription to purchase Ascorbic Acid in pharmacies. The price of 10 ampoules of 2 ml with a 5% solution of ascorbic acid is about 40 rubles. A jar of 50 mg tablets of vitamin C costs 20-25 rubles, and a package of 25 mg tablets, which contain glucose, costs about 10-20 rubles.

Ascorbic acid can be bought not only at the pharmacy, but also often at the checkout in the supermarket

Storage conditions and shelf life

The place where you need to place Ascorbic acid for better preservation should not be very humid, hot or lit. In addition, you need to keep the drug where small children cannot reach it.

The shelf life of tablets with ascorbic acid is 1-3 years. different manufacturers, 5% solution for injections is stored for up to a year, 10% solution and pills - 18 months from the date of release.

Reviews

Parents generally speak well of ascorbic acid preparations. Sweet ascorbic acid is liked by children and is considered by most adults to be a useful supplement, especially during the cold season. Moms are attracted by the ability of such a medicine to prevent ARVI, strengthen the immune system and blood vessels. In their reviews, they also praise Ascorbic acid for its pleasant taste, low cost and availability in pharmacies.

Most reviews do not mention any disadvantages of this drug. Only in some children Ascorbic acid causes allergies, but larger number Young patients tolerate the drug well.

Analogs

Ascorbic acid for children in tablets, dragees or injection form can be replaced with other drugs that can compensate for the lack of vitamin C or prevent hypovitaminosis. These include:

• Asvitol. The drug is presented with vitamin C in tablets (25-50 mg) and chewable tablets (200 mg).
• Ascovit. This vitamin C is produced in powder (packaged in 1 g bags), from which a drink with green tea and hibiscus flavor or orange flavor is prepared. This drug is also available in effervescent tablets 500 or 1000 mg of ascorbic acid with orange and lemon flavor.

Gross formula

Pharmacological group of the substance Ascorbic acid

Nosological classification (ICD-10)

CAS Code

Characteristics of the substance Ascorbic acid

Vitamin remedy (vitamin C). Ascorbic acid is a white crystalline powder with a sour taste. Easily soluble in water (1: 3.5), slowly soluble in ethanol (1:30), absolute alcohol (1:50), glycerin (1:100), propylene glycol (1:20). Solubility in water: 80.0% at 100 °C; 40.0% at 45 °C. Practically insoluble in ether, benzene, chloroform, petroleum ether, oils, fats. Under the influence of air and light it gradually darkens. When dry, it is stable in air. aqueous solutions oxidize quickly in air. Molecular mass 176,13.

Sodium ascorbate - small crystals, freely soluble in water: 62 g/100 ml at 25 °C, 78 g/100 ml at 75 °C.

Most primates (including humans) Guinea pigs, some birds and fish cannot synthesize vitamin C. In the human body, the necessary supply is replenished through food intake.

For medical purposes, ascorbic acid is obtained synthetically.

Pharmacology

Has pronounced antioxidant properties. Regulates H+ transport in many biochemical reactions, improves the use of glucose in the tricarboxylic acid cycle, participates in the formation of tetrahydrofolic acid and tissue regeneration, the synthesis of steroid hormones, collagen, procollagen, carnitine, and hydroxylation of serotonin. Maintains the colloidal state of the intercellular substance and normal capillary permeability (inhibits hyaluronidase). Activates proteolytic enzymes, participates in the metabolism of aromatic amino acids, pigments and cholesterol, promotes the accumulation of glycogen in the liver. Due to the activation of respiratory enzymes in the liver, it enhances its detoxification and protein-forming functions, increases the synthesis of prothrombin. Improves bile secretion, restores exocrine function of the pancreas and endocrine function of the thyroid gland. Regulates immunological reactions (activates the synthesis of antibodies, C3 component of complement, interferon), promotes phagocytosis, increases the body's resistance to infections. Has anti-inflammatory and anti-allergic effects. Inhibits the release and accelerates the degradation of histamine, inhibits the formation of PG and other mediators of inflammation and anaphylaxis. Reduces the need for vitamins B1, B2, A, E, folic acid, pantothenic acid. Insufficiency of ascorbic acid leads to the development of hypovitaminosis, in severe cases - vitamin deficiency (skorbut, scurvy).

Absorbed into small intestine(duodenum, partially in the ileum). With an increase in dose to 200 mg, up to 70% is absorbed; with a further increase in dose, absorption decreases (50-20%). Gastrointestinal pathology (ulcers, constipation, diarrhea), helminthic infestation, giardiasis, drinking fresh fruit and vegetable juices, alkaline drinking - reduce the utilization of ascorbate in the intestines. Cmax after oral administration is achieved within 4 hours. The degree of binding to plasma proteins is low (about 25%). Easily penetrates into leukocytes, platelets, and then into all tissues; the highest concentrations are found in glandular tissue. Deposited in the posterior lobe of the pituitary gland, adrenal cortex, ocular epithelium, interstitial cells of the seminal glands, ovaries, liver, brain, spleen, pancreas, lungs, kidneys, intestinal wall, heart, muscles, thyroid gland. Passes through the placenta. Metabolized, mainly in the liver, into deoxyascorbic acid and further into oxaloacetic and diketogulonic acids. Unchanged ascorbate and metabolites are excreted in urine, feces, sweat, breast milk. Excreted during hemodialysis.

At high doses, when plasma concentrations reach more than 1.4 mg/dL, excretion increases sharply, and increased excretion may persist after discontinuation of administration. Smoking and consumption ethyl alcohol accelerate destruction (conversion into inactive metabolites), sharply reducing reserves in the body.

When used as vaginal tablets ascorbic acid lowers vaginal pH, inhibiting bacterial growth, and helps restore and maintain normal indicators pH and vaginal microflora (Lactobacillus acidophilus, Lactobacillus gasseri). Thus, when the vaginal pH decreases over several days, there is a pronounced suppression of growth anaerobic bacteria, as well as restoration of normal flora.

Application of the substance Ascorbic acid

Hypovitaminosis C, hemorrhagic diathesis, capillary toxicosis, hemorrhagic stroke, bleeding (including nasal, pulmonary, uterine), infectious diseases, idiopathic methemoglobinemia, intoxication, incl. chronic intoxication iron supplements, alcoholic and infectious delirium, acute radiation sickness, post-transfusion complications, liver diseases (Botkin's disease, chronic hepatitis and cirrhosis), gastrointestinal diseases (achylia, peptic ulcer, especially after bleeding, enteritis, colitis), helminth infections, cholecystitis, adrenal insufficiency (Addison's disease), sluggishly healing wounds, ulcers, burns, bone fractures, dystrophy, physical and mental overload, the period of convalescence after illnesses, pregnancy (especially multiple births, against the background of nicotine or drug addiction), lactation, hemosiderosis, melasma, erythroderma, psoriasis, chronic common dermatoses. In laboratory practice - for marking red blood cells (together with sodium chromate 51 Cr).

Vaginal tablets - chronic or recurrent vaginitis caused by anaerobic flora (due to altered vaginal pH); normalization of disturbed vaginal microflora.

Contraindications

Hypersensitivity, thrombophlebitis, tendency to thrombosis, vulvovaginal candidiasis(for vaginal tables).

Restrictions on use

Diabetes mellitus, glucose-6-phosphate dehydrogenase deficiency, hemochromatosis, sideroblastic anemia, thalassemia, hyperoxaluria, oxalosis, urolithiasis.

Use during pregnancy and breastfeeding

The minimum daily requirement for ascorbic acid is II-III trimesters pregnancy - about 60 mg. It should be borne in mind that the fetus can adapt to high doses of ascorbic acid taken by a pregnant woman, and then the newborn may develop withdrawal symptoms. It has been reported that treatment with high doses of vitamin C taken during pregnancy is associated with a risk of developing scurvy in newborns, and with intravenous administration in high doses, there is a risk of miscarriage due to estrogenemia ( non-teratogenic effects).

The minimum daily requirement during lactation is 80 mg. A maternal diet containing adequate amounts of ascorbic acid is sufficient to prevent deficiency in infant. Theoretically, there is a danger to the child when the mother uses high doses of ascorbic acid (it is recommended for a nursing mother not to exceed daily requirement in ascorbic acid).

For injection forms. Animal reproduction studies using ascorbic acid injections have not been conducted. It is not known whether vitamin C can injection pregnant women have an embryotoxic effect or impair reproductive ability. Injection forms can be prescribed during pregnancy only if absolutely necessary.

Side effects of the substance Ascorbic acid

From the outside of cardio-vascular system and blood (hematopoiesis, hemostasis): thrombocytosis, hyperprothrombinemia, erythropenia, neutrophilic leukocytosis.

From the outside nervous system and sense organs: with too rapid intravenous administration - dizziness, weakness.

From the gastrointestinal tract: when taken orally - irritation of the gastrointestinal mucosa (nausea, vomiting, diarrhea), diarrhea (when taking doses of more than 1 g / day), damage to tooth enamel (with intensive use chewable tablets or resorption of oral forms).

From the side of metabolism: metabolic disorders, inhibition of glycogen synthesis, excessive formation of corticosteroids, sodium and water retention, hypokalemia.

From the outside genitourinary system: increased diuresis, damage to the glomerular apparatus of the kidneys, formation of oxalate urinary stones(especially with long-term use in doses of more than 1 g / day).

Allergic reactions: skin rash, skin hyperemia.

Others: pain at the injection site (with intramuscular injection). For vaginal tablets: local reactions- burning or itching in the vagina, increased mucous discharge, hyperemia, swelling of the vulva.

Interaction

Increases the blood concentration of salicylates (increases the risk of developing crystalluria), ethinyl estradiol, benzylpenicillin and tetracyclines, reduces the concentration of oral contraceptives. Acetylsalicylic acid, oral contraceptives, fresh juices And alkaline drink reduce absorption and absorption. Increases the activity of norepinephrine. Reduces the anticoagulant effect of coumarin and heparin derivatives. Improves the absorption of iron preparations in the intestines (by converting ferric iron to divalent iron). At simultaneous use with deferoxamine, increased tissue toxicity of iron is possible, incl. cardiotoxicity and development of heart failure. Increases the overall clearance of ethyl alcohol. May affect the effectiveness of disulfiram in treatment chronic alcoholism. Quinoline drugs, calcium chloride, salicylates, corticosteroids, when used for a long time, deplete vitamin C reserves. A solution of ascorbic acid, when mixed in one syringe, enters into a chemical interaction with many drugs.

Overdose

Symptoms: with long-term use of large doses (more than 1 g) - headache, increased excitability of the central nervous system, insomnia, nausea, vomiting, diarrhea, hyperacid gastritis, ulceration of the gastrointestinal mucosa, inhibition of the function of the insular apparatus of the pancreas (hyperglycemia, glucosuria), hyperoxaluria, nephrolithiasis (calcium oxalate), damage to the glomerular apparatus of the kidneys, moderate pollakiuria (when taking a dose of more than 600 mg/day).

Reduced capillary permeability (possible deterioration of tissue trophism, increased blood pressure, hypercoagulation, development of microangiopathies).

When administered intravenously in high doses, there is a threat of miscarriage (due to estrogenemia), hemolysis of red blood cells.

Routes of administration

Inside, i/m, IV, intravaginal.

Precautions for the substance Ascorbic acid

When prescribing IV solutions, you should avoid administering them too quickly. During long-term treatment Monitoring of renal function, blood pressure and glucose levels is necessary (especially when prescribing high doses). Use extreme caution when prescribing high doses to patients with urolithiasis, diabetes mellitus, a tendency to thrombosis, receiving anticoagulant therapy, and being on a salt-free diet.

Ascorbic acid, as a reducing agent, can distort the results of various laboratory tests (blood glucose, bilirubin, transaminase activity, LDH, glucose in urine, including causing false-negative results of fecal occult blood tests).

When used in the form of vaginal tablets, ascorbic acid does not inhibit the growth of fungal flora of the vagina. Manifestations such as burning and itching may be due to the presence of a concomitant asymptomatic fungal infection, so if these symptoms occur, an analysis should be performed to exclude a fungal infection. Breaks in the use of vaginal tablets due to intercyclic or menstrual bleeding not required.

Interactions with other active ingredients

Trade names

Tradename: ASCORBIC ACID

International nonproprietary name:

Dosage form:

Compound:

Description
Dragee is greenish-yellow or yellow in color and has a regular spherical shape. The surface of the dragee must be flat, smooth, and uniform in color.

Pharmacotherapeutic group
A drug that regulates metabolic processes.
Vitamin preparation.

ATX code A11GA01

Pharmacological properties
Ascorbic acid is actively involved in many redox reactions and has a nonspecific general stimulating effect on the body. Increases the body's adaptive abilities and its resistance to infections; promotes regeneration processes.

Indications for use
Prevention and treatment of hypo- and vitamin C deficiency;
As aid: hemorrhagic diathesis, nasal, uterine, pulmonary and other bleeding, against the background of radiation sickness; overdose of anticoagulants, infectious diseases and intoxications, liver diseases, nephropathy of pregnancy, Addison's disease, slow-healing wounds and bone fractures. dystrophies and others pathological processes. The drug is prescribed for increased physical and mental stress, during pregnancy and breastfeeding, during the period of recovery after serious long-term illnesses.

Contraindications
Increased sensitivity to the components of the drug, thrombophlebitis, tendency to thrombosis, diabetes mellitus.

Carefully: hyperoxalaturia, renal failure, hemochromatosis, thalassemia, polycythemia, leukemia, sideroblastic anemia, glucose-6-phosphate dehydrogenase deficiency, sickle cell anemia. Progressive malignant diseases, pregnancy.

Directions for use and doses
The drug is taken orally after meals.
For prevention: adults 0.05-0.1 g (1-2 tablets) per day, children over 5 years old 0.05 g (1 tablet) per day.
For treatment: adults 0.05-0.1 g (1-2 tablets) 3-5 times a day, children from 5 years old 0.050.1 g (1-2 tablets) 2-3 times a day.
During pregnancy and breastfeeding, 0.3 g (6 tablets) per day for 1015 days, then 0.1 g (2 tablets per day) per day.

Side effect
From the central nervous system (CNS): headache, feeling of fatigue, with prolonged use of large doses - increased excitability of the central nervous system, sleep disturbances.
From the outside digestive system: mucosal irritation gastrointestinal tract, nausea, vomiting, diarrhea, stomach cramps.
From the outside endocrine system: inhibition of the function of the insular apparatus of the pancreas (hyperglycemia, glycosuria).
From the urinary system: when used in high doses, hyperoxalaturia and the formation of urinary stones from calcium oxalate.
From the cardiovascular system: thrombosis, when used in high doses - increased blood pressure, development of microangiopathies, myocardial dystrophy Allergic reactions: skin rash, rarely - anaphylactic shock.
Laboratory indicators: thrombocytosis, hyperprothrombinemia, erythropenia, neutrophilic leukocytosis, hypokalemia.
Others: hypervitaminosis, feeling of heat, with prolonged use of large doses - sodium (Na +) and fluid retention, metabolic disorders of zinc (Zn 2+), copper (Cu 2+).

Overdose
When taking more than 1 g per day, heartburn, diarrhea, difficulty urinating or red urine, and hemolysis (in patients with glucose-6-phosphate dehydrogenase deficiency) are possible.
If any side effects you should stop taking the drug and consult a doctor.

Interaction with others medicines
Increases the concentration of benzylpenicillin and tetracyclines in the blood; at a dose of 1 g/day increases the bioavailability of ethinyl estradiol.
Improves the absorption of iron preparations in the intestines (converts ferric iron to divalent iron); may increase iron excretion when used concomitantly with deferoxamine.
Acetylsalicylic acid (ASA), oral contraceptives, fresh juices and alkaline drinks reduce absorption and absorption.
When used simultaneously with ASA, the urinary excretion of ascorbic acid increases and the excretion of ASA decreases. ASA reduces the absorption of ascorbic acid by approximately 30%.
Increases the risk of developing crystalluria when treated with salicylates and sulfonamides short acting, slows down the excretion of acids by the kidneys, increases the excretion of drugs that have an alkaline reaction (including alkaloids), and reduces the concentration of oral contraceptives in the blood.
Increases the overall clearance of ethanol, which, in turn, reduces the concentration of ascorbic acid in the body.
Quinoline drugs (fluoroquinolones, etc.), calcium chloride, salicylates, and glucocorticosteroids with long-term use deplete ascorbic acid reserves.
When used simultaneously, it reduces the chronotropic effect of isoprenaline.
Long-term use or use in high doses may interfere with the disulfiram-ethanol interaction.
In high doses, it increases the renal excretion of mexiletine.
Barbiturates and primidone increase the excretion of ascorbic acid in the urine.
Reduces therapeutic effect antipsychotics(phenothiazine derivatives), tubular reabsorption of amphetamine and tricyclic antidepressants.

special instructions
Due to the stimulating effect of ascorbic acid on the synthesis of corticosteroid hormones, it is necessary to monitor renal function and blood pressure.
With long-term use of large doses, inhibition of the function of the pancreatic insular apparatus is possible, so it must be regularly monitored during treatment.
In patients with increased content iron in the body, ascorbic acid should be used in minimal doses.
Prescribing ascorbic acid to patients with rapidly proliferating and intensively metastasizing tumors can aggravate the process.
Ascorbic acid, as a reducing agent, can distort the results of various laboratory tests (blood glucose, bilirubin, transaminase activity, LDH).
Use during pregnancy and breastfeeding
The minimum daily requirement for ascorbic acid is P-P trimesters pregnancy - about 60 mg.
The minimum daily requirement during breastfeeding is 80 mg. A mother's diet containing adequate amounts of ascorbic acid is sufficient to prevent vitamin C deficiency in an infant (it is recommended that a nursing mother not exceed the maximum daily requirement for ascorbic acid).

Release form
200 tablets in polymer jars BP-60-X or BP-60, or “BP-60-X with stopper”.
The stopper (case) of the “BP-60 X with stopper” can contains instructions for medical use without putting the can in the pack.
A polymer jar BP-60-X or BP-60 is placed in a cardboard pack along with instructions for medical use.

Best before date
1 year 6 months.
Do not use after the date indicated on the package.

Storage conditions
In a dry place, protected from light.
Keep out of the reach of children.

Conditions for dispensing from pharmacies
Over the counter

Manufacturer and organization accepting claims:
JSC Pharmstandard-UfaVITA, 450077 Ufa, st. Khudayberdina, 28.

Release form: Solid dosage forms. Powder for oral use.

General characteristics. Compound:

Pharmacological properties:

Indications for use:

Important! Get to know the treatment

Directions for use and dosage:

Features of application:

Side effects:

Interaction with other drugs:

Contraindications:

Overdose:

Storage conditions:

In a dry place, protected from light, out of reach of children, at a temperature not exceeding 25 °C.

Vacation conditions:

Over the counter

Package:

Powder for the preparation of a solution for oral administration, 1 g and 2.5 g each. 1 g and 2.5 g each in heat-sealable bags made of combined film material or packaging paper with a polymer coating, or paper with a polyethylene coating for packaging medical supplies, or from paper with a single layer of polyvinylidene chloride coating.
5, 10, 20, 50, 100 packets per pack with an equal number of instructions for use.

Vitamin C - biologically active substance necessary for the normal functioning of the body. Found in many foods, but most of all in vegetables and fruits. Synthetic vitamin pharmaceutical enterprises produce through the fermentation of glucose. The release forms are different: dragees, tablets, powders and injection solution in ampoules.

General characteristics composition

Ascorbic acid 50 mg (dragees) is a white, light green or yellowish ball that contains 0.05 g of vitamin C as an active ingredient. Auxiliary components are mineral oil, sugar, molasses, talc, yellow wax, fruit essence and quinoline dye.

Pharmacological properties

Ascorbic acid is a water-soluble vitamin, essential in redox reactions; affects the metabolism of proteins, lipids, amino acids and carbohydrates, the biosynthesis of collagen, hemoglobin, steroid hormones and insulin. Promotes the regeneration of connective and bone tissues, strengthens the walls of capillaries.

Vitamin C improves iron absorption and promotes its deposition. It has a general stimulating effect, increases the body's ability to adapt and resist infections, reduces intoxication and is a powerful antioxidant.

The vitamin is adsorbed into small intestine, penetrates into the elements of the blood (leukocytes, platelets and, to a lesser extent, into erythrocytes and plasma), and then into all tissues of the body.

The main route of excretion is in the urine; in addition, the substance is excreted in feces and sweat.

Indications for use of Ascorbic acid in tablets 50 mg

The vitamin preparation is prescribed for prevention and as an adjuvant in the treatment of various conditions:

How to take Ascorbic acid in tablets 50 mg?

The drug should be taken orally after meals with a small amount of water. Doctors do not recommend taking the vitamin shortly before bedtime, as it has a mild stimulating effect.

Prophylactic daily intake for an adult - 0.05 or 0.1 g; For treatment, 1-2 tablets are prescribed up to 5 times a day.

At severe cold the dosage is increased 2-3 times (for 5-7 days).

Contraindications

Hypersensitivity to the main thing active substance or additional ingredients of the drug, thrombophlebitis or a tendency to thrombosis. The drug in pill form is not prescribed to children under 5 years of age.

Use vitamin C with caution when treating patients with signs of oxalaturia, hereditary hemochromatosis, or functional disorders kidneys, with diabetes mellitus, some forms of anemia and progressive tumor diseases.

Side effects of Ascorbic acid in tablets 50 mg

When using the drug, you may experience unwanted reactions from various systems:

• CNS - headache, sleep disturbances, increased excitability of the nervous system;
• Gastrointestinal tract - nausea, vomiting, stomach cramps, diarrhea and symptoms of irritation of the digestive tract mucosa;
• urination - formation of oxalate stones (with long courses of treatment);
• cardiovascular system - increased blood pressure, thrombocytosis, erythropenia, neutrophilic leukocytosis, hemolysis (destruction of red blood cells);
• endocrine system - glucosuria or hyperglycemia.

An allergy to the drug manifests itself as skin rash, redness and swelling. In case of hypersensitivity, an anaphylactic reaction is possible in rare cases.

Overdose

Significant excess of the dosage - consumption of more than 1 g per day - can provoke diarrhea, dysuria, change in urine color (from pink to red). In such cases, you should stop taking the vitamin and consult a doctor.

Exceeding the dosage to 20-25 g poses a threat to life (especially for a child).

Use during pregnancy and breastfeeding

Pregnant and lactating women can take medications and biologically active agents only as prescribed by a specialist.

In case of deficiency, the vitamin is prescribed for 1.5-2 weeks, 6 tablets per day, then the dose is reduced to 2 pieces. per day, the duration of the course is determined by the attending physician.

Use in children

For the purpose of prevention and nutritional adjustment, children from 5 years of age are recommended to take 1 tablet (0.05 g) per day. The dosage of the vitamin during treatment can be increased depending on age to 0.15-0.3 g per day.