Vitamin C effervescent tablets: benefits and harms. Vitamin C effervescent tablets

Every person needs vitamin compounds daily, and for children they sufficient quantity vitally important, because vitamins support growth processes in the child’s body and are required for proper development child. At the same time, vitamins can enter the child’s body both with food and in the form of complex supplements.

Supplements used in childhood are produced in different shapes. One of them is effervescent tablets. Such vitamins have their own advantages and features of administration, which are important for parents to know about before purchasing them.

Benefits of Effervescent Children's Vitamins

Contains effervescent vitamin complexes there are compounds that, when released into water, form carbon dioxide. As a result, the solid tablet loosens and dissolves, and the hissing bubbles that appear during this process give rise to the name of this form of vitamin supplements.

The main advantages of such vitamins are:

1. Improved digestibility and safety for the gastrointestinal tract. When dissolved in water vitamin tablet enters the digestive tract, it is better absorbed and does not have any harmful effects on the gastric mucosa.
2. Pleasant taste. From effervescent vitamins it turns out delicious drink with a pleasant smell. Many children like it, so giving this vitamin drink is much easier than hard tablets and capsules.

Disadvantages of Effervescent Vitamins

Despite the advantages, effervescent vitamin supplements also have some disadvantages:

• The presence of citric acid in their composition harms tooth enamel, especially if you use such vitamins very often.
• The drug cannot be taken without a glass of water.

Features of application

Effervescent vitamin supplements are usually taken with meals. The tablet is dissolved in a glass of water, after which the resulting drink is drunk. To reduce the risk of damage to tooth enamel vitamin drink It is recommended to drink through a straw.

Review of popular

The selection of effervescent vitamins for a child should be carried out together with a doctor, since the pediatrician will recommend the optimal complex suitable for your baby.

The most common children's effervescent vitamins are:

1. Multifort for children. Recommended for children over four years of age, these orange tablets contain not only vitamins (13 compounds), but also 10 minerals, including iodine and zinc. Also, these effervescent tablets contain rosehip extract, due to which the supplement has a general strengthening effect and reduces the risk of colds. At 4-7 years of age, the child is given one tablet per day, and for children over seven years of age, the daily dose can be increased to two tablets.

2. Supradin. This supplement, in the form of effervescent tablets, contains 12 vitamin compounds and 8 minerals. Each tablet yields lemon drink. It is given to children over 12 years of age once a day.

About the benefits ascorbic acid (vitamin C) everyone knows. During the off-season, many people try to consume more products that contain it. As a rule, high hopes are placed on fruits and berries. But, unfortunately, if these are not independently grown fruits, vegetables and berries, then they contain vitamins minimal amount, they are collected when they are not ripe and used for cultivation chemical substances, and during long-term storage they even lose what they have.

To maintain immunity and vitality In the autumn-spring period, I always take ascorbic acid prophylactically. I buy it both in powders and in effervescent tablets and small dragees.

Of the effervescent options, I like it best ascorbic acid manufacturer Hemofarm. This manufacturer produces effervescent tablets in two versions: 250 mg and 1000 mg in one tablet.

Externally, the tablets are no different, they are the same size and their solution also has the same citrus taste. (The packaging in the photo is slightly different because the company changed the design, and now both dosages look like the 1000 mg one.)

The drug is available in the form of soluble tablets of a fairly large diameter, having the classic smell of ascorbic acid with an admixture of citrus aroma. The tablets are packaged in a metal tube with a plastic cap, 20 pieces each, and then in a cardboard box.

Cost from 130 rubles for a dosage of 250 mg, up to 250 rubles for a dosage of 1000 mg. I sometimes take a large dosage and then just break it in half approximately. It is clear that the dosage in each half is not exactly 500 mg, but approximately, but it turns out cheaper, and I don’t overdo it with the amount of acid.

VITAMIN C plays important role in the regulation of redox processes, carbohydrate metabolism, blood clotting, tissue regeneration; participates in the synthesis of corticosteroids, collagen and procollagen; normalizes capillary permeability, reduces the need for vitamins B1, B2, A, E, folic acid, pantothenic acid, helps to increase the body's resistance, which is apparently associated with the antioxidant properties of ascorbic acid.

The deficiency manifests itself in fatigue, bleeding gums, in general decline the body's resistance to infections; with advanced hypovitaminosis C, scurvy may appear, which is characterized by loosening, swelling and bleeding of the gums, tooth loss, and minor subcutaneous hemorrhages. Overdose may cause dysfunction of the liver and pancreas.

Despite the fact that this seemingly simple vitamin has a significant effect on all processes in the human body, it is not worth taking it in large dosages, even if it is a water-soluble substance and is freely excreted from the body in excess. If there is too much of it, then provide negative impact It will have time to affect the body even before the kidneys get rid of it.

There are certain indications for taking ascorbic acid.

INDICATIONS:

For tablets containing 1000 mg ascorbic acid

- treatment of vitamin C deficiency.

For tablets containing 250 mg ascorbic acid

Treatment and prevention of hypo- and avitaminosis C, incl. caused by a state of increased need for ascorbic acid with:

- increased physical and mental stress;

- V complex therapy colds, ARVI;

- for asthenic conditions;

- during the recovery period after illnesses.

- pregnancy (especially multiple pregnancy, against the background of nicotine or drug addiction).

It is also necessary to remember that this is still medicinal product and its excessive intake into the body may be contraindicated, and the development of side effects.

CONTRAINDICATIONS FOR USE:

- childhood up to 18 years (for this dosage form);

At long-term use in large doses (more than 500 mg): diabetes, hyperoxaluria, nephrolithiasis, hemochromatosis, thalassemia;

- increased sensitivity to the components of the drug

WITH caution: diabetes mellitus, glucose-6-phosphate dehydrogenase deficiency, hemochromatosis, sideroblastic anemia, thalassemia, hyperoxaluria, oxalosis, urolithiasis.

I try not to take ascorbic acid in any form, much less in the form of effervescent tablets during the period of exacerbation of my chronic gastritis, so as not to expose the gastric mucosa to excessive acid, which is already sufficient. And in general, I try to take vitamin C not on an empty stomach, so as not to suffer from heartburn later. People with erosive gastritis and those suffering from gastric ulcers and duodenum In general, it is advisable to refrain from taking ascorbic acid in this form.

In addition, you need to remember that the tablet, no matter how funny it sounds, must be dissolved in water and not dissolved in the mouth. Otherwise, this can lead to damage to the tooth enamel and even to the development of stomatitis with the formation of ulcers.

The tablets dissolve in water quite quickly, literally within 3-4 minutes, forming a greenish-yellow solution with a characteristic smell of vitamin C and a fruity-citrus taste. A kind of "Fanta".

Dosages will depend on how much this drug is missing in the body, that is, it is prevention of hypovitaminosis or treatment.

Dosage regimen:

The drug is taken orally after meals. 1 tablet is dissolved in a glass of water (200 ml). The tablets should not be swallowed, chewed or dissolved in the mouth.

Treatment of vitamin C deficiency: 1000 mg/day.

Treatment and prevention of hypo- and vitamin deficiency C: 250 mg 1-2 times/day.

At pregnancy prescribe the drug at maximum daily dose- 250 mg for 10-15 days.

It should also be remembered that if a person simultaneously takes other vitamins containing ascorbic acid, then the dosage must be controlled more carefully so as not to exceed the daily requirement.

It is extremely difficult to prove the positive effects of ascorbic acid, like any other vitamins, on the body., since all processes take place on cellular level. I can’t say if I suffered more or less from colds, or whether it really makes my skin better, but I would like to hope that it would be easier for the body to survive the cold season with an additional supply of vitamin C.

This spring, my sick husband recovered much faster by taking vitamin C than last time. So we were still able to observe the effect of the drug.

I recommend ascorbic acid in effervescent tablets, but with certain reservations regarding the dosage regimen.

The human body cannot exist normally without biologically active substances, which we call vitamins. Their role in metabolic processes is simply irreplaceable. They act as accelerators of many biochemical reactions, without which the growth and development of the body is simply impossible to imagine. Based on the ability of vitamins to dissolve in water or fat, they are divided into water-soluble and fat-soluble. Among water-soluble vitamins, the most famous are vitamins of group C.

What is vitamin C?

In nature, vitamin C is represented by ascorbic acid, as well as its derivatives: dehydroascorbic acid and ascorbigen. The first derivative is formed due to the reduction of ascorbic acid with compounds containing sulfhydryl bonds. Ascorbigen is formed by adding amino acid or protein bases to ascorbic acid. All these modifications of vitamin C are highly soluble in water and have biological activity.

It is produced mainly in plants from glucose, and most of represented by ascorbigen, since it is less susceptible to oxidative processes. Some animals are also able to independently provide themselves with this vitamin, but human body must receive it from outside. Accordingly, natural sources of this vitamin would be plant food and some animal products such as liver and kidneys, fermented milk products.

Dosage forms

The body's needs for ascorbic acid are significantly greater than for other vitamins, which is about 0.1 g per day. It is not always possible to fill this norm only by regular products that we are used to eating. To prevent vitamin deficiency, medications containing ascorbic acid are used. It can be multivitamin complexes or single drugs. Single-component medications containing vitamins C are available in various dosage forms. This can be a powder in sachets, which is dissolved in water before use. warm water. One such bag costs about 12 rubles.

Exists liquid vitamin C in ampoules, which is widely used by cosmetologists to care for the skin of the face, neck and décolleté. It is used to make excellent masks that can reduce pigmentation, narrow pores, they promote the production of Vitamin C and participate in the metabolic processes of skin cells, which ensures greater saturation of them with oxygen. After such procedures, the skin takes on a radiant appearance.

Vitamin C in ampoules can be added to shampoo for washing hair or making masks. After regular use, the hair structure is restored, it becomes healthy and strong. C, the price of which for a pack of ten ampoules is 38 rubles, can be purchased in specialized pharmacies. Each ampoule of this vitamin contains 2 ml of a 5% ascorbic acid solution.

Still the most common dosage form- this is vitamin C in tablets. It can be chewable tablets with a dosage of 500 mg, taken after meals.

Another type of tablet is vitamin C effervescent. The drug is presented on the Russian pharmaceutical market by the company Multivita under trade name“Multivita vitamin C 1000 mg” and “Multivita vitamin C 250 mg”. As you can see, effervescent tablets come in two dosages of 250 mg and 1000 mg. Vitamin C 1000 mg is in greatest demand in pharmacies. The dosage is selected based on its daily requirement in the human body. Vitamin C, the price of which is about 200 rubles, is sold in plastic tubes of 20 tablets.

What is vitamin C for?

The effect of vitamin C on the body is varied; without its participation, the functioning of many organs and systems is disrupted.

The drug "Effervescent Vitamin C" (1000 mg) affects lipid metabolism, protein and carbohydrate metabolism. Thus, with its participation, procollagen and collagen molecules are synthesized, without which connective tissue cannot function normally. It is collagen that makes up the joint ligaments. skin, tendon fibers, cartilage, dental and bone tissue, it is also part of the walls of blood vessels. It allows you to quickly regenerate damaged skin and bone tissue.

Vitamin C (1000 mg) increases the production of antitoxins, which are responsible for strengthening the immune system, and increases the antiplatelet properties of blood platelets. Under the influence acetylsalicylic acid the formation of erythrocytes and leukocytes occurs, the action of phagocytic cells is enhanced, as well as the production of special interferon proteins that have antiviral activity. In addition, such proteins prevent cells from mutating, which prevents the development of tumors. With reduced immunity, the body's need to consume more ascorbic acid increases.

Located in tissue cells various organs, actively regulates them metabolic processes. With its participation, the level of glucose in the blood plasma decreases due to its conversion into glycogen, and also maintains the right level cholesterol indicators. Thus, vitamin C promotes the synthesis of cholesterol in liver cells, from which they are subsequently produced, improves the secretion of bile and the functioning of the parts of the pancreas responsible for external secretion.

In addition, vitamin C "Multivita 1000 mg" has antioxidant properties that prevent oxidative reactions in the body by neutralizing very active charged particles. This feature prevents cell aging and the development of all kinds of diseases.

Due to the action of ascorbic acid, there is a change in the lumen of small blood vessels, which leads to a decrease in blood pressure, the heart muscle begins to contract more often, and the penetration of substances through the vascular walls decreases.

active substance: 1 tablet contains ascorbic acid 95% granulated in terms of ascorbic acid 199.5 mg and sodium ascorbate in terms of ascorbic acid 300.5 mg;

Excipients: mannitol (E 421), sucrose, sodium cyclamate, orange or strawberry or strawberry or pineapple flavor, aspartame (E 951), stearic acid, azo dye “sunset yellow” (E 110) or azo dye carmoisin (E 122), or azo dye crimson 4R (E 124), or azo dye tartrazine (E 102), magnesium stearate, anhydrous colloidal silicon dioxide.

Dosage form

Chewable tablets.

Vitamin C 500 mg orange: tablets pink- orange color with an orange smell, sweet and sour taste, the upper and lower surfaces of which are convex. On one of the surfaces there are marks and the inscriptions “C” and “500”. White and bright orange inclusions are allowed on the surface of the tablets; the presence of powdery deposits and minor nicks.

Vitamin C 500 mg strawberry: violet tablets Pink colour with a strawberry smell, sweet and sour taste, the upper and lower surfaces of which are convex. On one of the surfaces there are marks and the inscriptions “C” and “500”. White and bright pink inclusions are allowed on the surface of the tablets; the presence of powdery deposits and minor nicks.

Vitamin C 500 mg strawberry: tablets of a faint pink color with a strawberry smell, sweet and sour taste, the upper and lower surfaces of which are convex. On one of the surfaces there are marks and the inscriptions “C” and “500”. White and pink inclusions are allowed on the surface of the tablets; the presence of powdery deposits and minor nicks.

Vitamin C 500 mg pineapple: yellow tablets with a pineapple odor, sweet and sour taste, the upper and lower surfaces of which are convex. On one of the surfaces there are marks and the inscriptions “C” and “500”. White and orange inclusions are allowed on the surface of the tablets; the presence of powdery deposits and minor nicks.

Manufacturer name and location

Stirolbiopharm LLC.

Ukraine, 84610, Donetsk region, Gorlovka metro station, st. Gorlovka division, 97.

Pharmacotherapeutic group

Vitamins. Simple drugs ascorbic acid (vitamin C).

ATC code A11G A01.

Vitamin C (ascorbic acid) belongs to the group of water-soluble vitamins. Ascorbic acid is essential for the proper functioning and formation of connective tissues, in particular intercellular substance and collagen. During collagen synthesis, it participates in the hydroxylation of proline and lysine in the peptide chain. Ascorbic acid is part of many redox reactions in the body and takes part in the metabolism of phenylalanine, tyrosine, folic acid, norepinephrine, histamine and some enzyme systems involved in the synthesis of lipids, proteins and in the hydroxyuvanni of carnitine or serotonin. Ascorbic acid stabilizes capillary walls and increases iron absorption.

Ascorbic acid is easily absorbed from the gastrointestinal tract and penetrates into tissues. The highest concentrations are found in the adrenal glands, pituitary gland and intestinal wall. Biotransformed in the liver. The main metabolite of ascorbic acid is oxalic acid, which is excreted in the urine. Excretion in urine is a sign of saturation of the body with vitamin C. Ascorbic acid penetrates the placenta and into breast milk. It can be removed from the body using hemodialysis.

Indications for use

For the treatment of hypo- and vitamin deficiency C. Ensuring the body's increased need for vitamin C during acute respiratory and infectious diseases;

• during the period of convalescence after serious illnesses, surgical interventions;
• for various intoxications, hemorrhagic diathesis, diseases connective tissue (rheumatoid arthritis), bleeding (nasal, pulmonary, uterine);
• at radiation sickness, hepatitis, cholecystitis, Addison's disease, for soft tissue injuries that heal slowly, infected wounds and bone fractures.

Contraindications

Hypersensitivity to ascorbic acid and other components of the drug.

Tendency to thrombosis, thrombophlebitis, diabetes mellitus, urolithiasis.

Children's age up to 14 years.

Particular caution should be used in patients with disorders of iron metabolism (hemosiderosis, hemochromatosis, thalassemia).

Fructose intolerance, glucose/galactose malabsorption syndrome.

Severe kidney disease.

Proper safety precautions for use

Since vitamin C has a mild stimulating effect, it is not recommended to take this medication late in the day.

Due to the stimulating effect of ascorbic acid on the formation of corticosteroid hormones, when used in large doses, monitoring of kidney function and blood pressure is necessary.

Use the drug with caution in case of increased blood clotting.

Patients should be prescribed with extreme caution:

• with glucose-6-phosphate dehydrogenase deficiency (high doses of ascorbic acid can provoke hemolytic anemia);
• with a history of nephrolithiasis (risk of hyperoxaluria and oxalantine deposits in the urinary tract after taking large doses of ascorbic acid).

Long-term use of large doses of ascorbic acid can accelerate its own metabolism, which is why paradoxical hypovitaminosis may occur after treatment is discontinued. Do not exceed the recommended dose.

Should not be used simultaneously with other medications containing vitamin C.

Drugs should be used with caution for polycythemia and leukemia.

Absorption of ascorbic acid may be impaired by impaired intestinal motility, enteritis or achylia (inhibition of gastric secretion).

It should be borne in mind that the use of vitamin C in high doses may change some indicators laboratory tests(blood glucose, bilirubin, transaminases, uric acid s, creatine, inorganic phosphates). May be negative result Availability studies hidden blood in feces.

Use during pregnancy or breastfeeding

Long-term use of vitamin C higher doses during pregnancy can negatively affect the development of the fetus, so you should adhere to the recommended dosage.

If breastfeeding, you should refrain from taking the drug, since ascorbic acid passes into breast milk.

The ability to influence the reaction rate when driving a vehicle or working with other mechanisms

Does not affect.

Children

Directions for use and doses

Take the drug orally after meals, chewing the tablet.

Adults and children over 14 years old with therapeutic purpose you need to take 1 tablet (500 mg) per day. Treatment period is 10-15 days.

For acute respiratory and infectious diseases for adults, it is recommended to take 1-2 tablets (500-1000 mg) per day (in 2 divided doses) for 7-10 days.

The duration of treatment is determined by the doctor depending on the patient’s condition and the course of the disease.

Overdose

Vitamin C is well tolerated. Ascorbic acid is a water-soluble vitamin, its excess is excreted in the urine. However, with long-term use of vitamin C in large doses, inhibition of the function of the insular apparatus of the pancreas is possible, which requires monitoring the condition of the latter.

Overdose may lead to changes in the renal excretion of ascorbic and uric acids during urine acetylation with the risk of precipitation of oxalate stones.

The use of large doses of the drug may lead to vomiting, nausea or diarrhea, which disappear after its discontinuation.

Treatment is symptomatic.

Side effects

-from the outside digestive tract: when using more than 1 g per day - irritation of the mucous membrane of the digestive tract, heartburn, nausea, vomiting, diarrhea;

-from the urinary system: damage to the glomerular apparatus of the kidneys, renal failure, crystalluria, formation of urate, cystine and oxalate stones in the kidneys and urinary tract;

- allergic reactions: sometimes - eczema, urticaria, itching, angioedema, anaphylactic shock in the presence of sensitization;

-from the endocrine system: damage to the insular apparatus of the pancreas (hyperglycemia, glucosuria) and disruption of glycogen synthesis up to the onset of diabetes mellitus;

-from the cardiovascular system: arterial hypertension, myocardial dystrophy;

-from the hematopoietic system: thrombocytosis, hemolytic anemia, hyperprothrombinemia, erythrocytopenia, neutrophilic leukocytosis; in patients with deficiency of glucose-6-phosphate dehydrogenase of blood cells, it can cause hemolysis of red blood cells;

-from the outside nervous system: increased excitability, fatigue, sleep disturbance, headache;

-on the metabolic side: disturbance of zinc and copper metabolism.

Interaction with other drugs and other types of interactions

With simultaneous use, ascorbic acid enhances the absorption of iron, penicillin, ethinyl estradiol from gastrointestinal tract. Similar effect This also applies to aluminum, so this must be taken into account when simultaneously treating with antacids containing aluminum.

Ascorbic acid, when used simultaneously, reduces the effectiveness of heparin and anticoagulants.

Absorption of ascorbic acid is reduced with simultaneous use of oral contraceptives, consumption of fruit or vegetable juices, and alkaline drinking. Vitamin C can only be taken 2 hours after the deferoxamine injection. Long-term use of large doses of ascorbic acid reduces the effectiveness of treatment with disulfiram.

Large doses of the drug reduce the effectiveness of tricyclic antidepressants, neuroleptics - phenothiazine derivatives, tubular reabsorption of amphetamine, and interfere with the excretion of mexiletine by the kidneys.

Ascorbic acid increases total clearance ethyl alcohol. Quinolone drugs, calcium chloride, salicylates, tetracyclines, and corticosteroids with long-term use reduce ascorbic acid reserves in the body.

At high doses, ascorbic acid affects the resorption of vitamin B12.

Vitamin C increases the excretion of oxalate in the urine, thereby increasing the risk of oxalate stones forming in the urine.

Best before date

Storage conditions

Store in original packaging at a temperature not exceeding 25 °C out of the reach of children.

Package

Vitamin C 500 mg orange/strawberry/strawberry/pineapple:

12 tablets in a blister;

12 tablets per blister, 1 or 10 blisters per pack;

30 or 50 tablets in polymer containers in a pack or without a pack.

Vitamin C 500 mg orange:

6 tablets in a blister,

12 tablets per blister, 5 blisters per pack.