What to eat to improve the endometrium. Brief information about the endometrium

Article outline

For a woman who decides to get pregnant important issue is the condition of the endometrium of the uterus in its body. Therefore, for many, the topic of how to grow the endometrium becomes relevant.

For conception, it is necessary that this layer is of sufficient thickness and corresponds to healthy situation. The reasons for the deterioration can be many factors that fill the life of a modern woman. Improving the condition of the uterine lining can be achieved using folk remedies or traditional medications.

What functions does the endometrium perform?

The healthy endometrium in women is a glandular epithelium. It consists of a capillary network that supplies the remaining components of the endometrium, such as:

• cover cells;
• sector cells;
• basal cells;
• tubular glands;
• fibroblasts, histiocytes, lymphocytes and other stromal elements;
• prismatic epithelium.

All these parts depend on vascular network, which supplies them with the necessary microelements. It is she who is subsequently responsible for the development of the fetus and the onset of pregnancy. With the help of this system, the organ is cleansed of metabolic products.

The number of fibers and glands increases immediately with the onset of pregnancy. This is necessary in order to create construction material for the placenta and provide the developing fetus with oxygen and nutrients.

The mucous layer in a depleted state cannot serve as a site for attachment of a fertilized egg and will not provide conditions in the body for the growth of the fertilized egg. For pregnancy to occur, all qualitative indicators of the endometrium must be normal. Such as:

• thickness;
• structure;
• overall volume;

Throughout the entire menstrual cycle, the lining of the uterus in women undergoes serious changes under the influence of hormones. Therefore, all indicators should be assessed taking into account the phase of the menstrual cycle. The number of glands increases at the time of ovulation and decreases, being rejected in the absence of fertilization. Dead cells come out with menstrual flow. And then the entire mucous layer is restored under the influence of estrogens in female body.

The endometrium plays a key role in all fertilization processes. You can conceive a child only with a healthy and mature mucous layer of the uterine cavity. The depleted mucous membrane cannot accept ovum and give him a base of substances for the further development of the placental barrier.

Causes of emaciation

The most favorable period for conception is the middle of the menstrual cycle. At this time, the thickness of the endometrium should not be less than 1.1 cm. If the mucous layer is thickened, fertilization does not occur.

Maybe due to:

• hormonal imbalance (the most common cause);
• circulatory disorders in the pelvic organs;
• pathologies in the structure of the uterus;
• diseases of the endocrine system;
• inflammation in the uterine cavity;
• muscular underdevelopment of the organ;
• genetic pathologies;
• curettage and abortion.

Under treatment by medication and folk remedies. Before treatment, you must contact your doctor, undergo an examination and clarify the exact diagnosis.

You should consult a specialist at the first signs of illness.

Signs of endometrial shrinkage

The basic reason why the mucous layer does not reach the required thickness is the lack of the hormone estrogen in the woman’s body. The most important factor forcing you to consult a specialist is the absence of pregnancy for a long time or repeated miscarriages.

The endometrium of the uterus becomes thinner, but external manifestation it is not observed. Based on how you feel, you can note the following signs of pathology:

• Disruptions in the menstrual cycle;
• Headache;
• Increased sweating;
• Stopping body hair growth;
• Sudden changes in blood pressure;
• Scanty discharge during menstruation;
• Hot flashes;
• Tremor;
• Increased nervous excitability, insomnia and an unreasonable feeling of fear;
• Pain during sexual intercourse;
• Lack of orgasms;
• Joint pain and spasms in muscle tissue.

Lack of conception does not always accompany pathology of the mucosal layer. In some cases, pregnancy is possible. But this condition will be extremely difficult to resolve. Throughout the entire period, the woman is at risk of miscarriage, suffers from severe toxicosis and often does not carry the fetus to term.

An effective way to increase the endometrial layer can be chosen only after a thorough examination and diagnosis.

To do this, you need to contact a specialist at initial examination, in which he may question the presence of such a pathology. If there are signs of thinning, the specialist prescribes:

• Biopsy of the uterus. Fence biological material from the surface of the uterus can be carried out in several ways, at the discretion of the treating specialist. Pain relief depends on the chosen method of analysis;
• Ultrasound of the pelvic organs. The study allows us to evaluate not only the thickness of the endometrium, but also its structure;
• Determination of hormone levels in the blood. Detects the presence of failures and possible reason disturbances in the mucous layer of the uterus.

Diagnostic methods are prescribed when making a diagnosis and for monitoring purposes after the first course of treatment.

Why do women want to build up their mucous layer?

The main reason for the desire to increase the uterine mucosa to standard indicators- this is the desire to get pregnant. But this is not the only reason.

Many patients decide to undergo treatment due to general malaise and concerns about personal health.

An increase is necessary in order to:

• get pregnant;
• restore the normal layer after curettage;
• increasing the volume of the endometrium so that the fetus takes root;
• establish all body functions and ensure normal attachment of the fetus before IVF;

You can enlarge the endometrium when planning pregnancy with the help of certain drug therapies and folk remedies.

How to enlarge the endometrium with medications

After production accurate diagnosis, the doctor determines the reason why the uterine lining does not recover properly during the menstrual cycle.

To correct the condition, the following medications are prescribed:

• medications that affect the production of hormones, in particular estrogens;
• hormonal drugs based on progesterone, which build up the endometrium;
• salicylic medications.

The form of release depends on certain factors and is prescribed at the discretion of the attending physician. These can be tablets, drops or local medications (suppositories, gels, decoctions for douching).

You cannot prescribe a list of medications for yourself. Therapy must be approached comprehensively and can only be prescribed by a highly qualified doctor. Most medications are hormonal and should be taken with strict monitoring of the patient's condition.

Proginov tablets are part of anti-inflammatory therapy and are hormonal. The product should not be taken on the recommendation of friends or at personal discretion. To establish a course of treatment, there must be clear indicators and a diagnostic conclusion.

During Proginov therapy, the endometrial layer can be built up due to the inclusion of estrogens and estradiol in the medication. The drug is used in the following ways:

• Cyclic scheme;
• Continuous circuit;
• Combined scheme.

Direct contraindications to taking the drug are pregnancy, lactation, kidney and liver pathology, a tendency to thrombus formation, lactose intolerance and childhood up to 18 years old.

Divigel has an estrogenic effect on the mucous layer and this allows the endometrium to quickly grow. An antitumor drug allows you to eliminate hormone deficiency in the female body and get rid of pathology.

The standard dosage of Divigel is equal to 1 g of gel per day. However, the optimal course and dosage is determined individually, at the discretion of the doctor. The drug is used externally and applied to the buttocks, thighs, lower back and lower abdomen. The procedure is performed once a day.

The gel should not be applied to mucous membranes or breasts. Direct contraindications are:

• Increased blood sugar levels;
• Diseases of the urinary system and liver;
• The body's tendency to form plaques in blood vessels;
• Bleeding;
• Tumor diseases;
• The period of gestation and lactation.

Hormel drops are an alcohol preparation that helps restore the mucosal layer. This homeopathic remedy is used as a supplement in complex treatment and with premenstrual syndrome.

Oral drops contain a number of components that, due to biological activity, normalize the functions of the female reproductive system.

Many women give preference to this drug due to its naturalness and naturalness.

The medicine should be taken by diluting 10 drops in 100g of water. You need to drink this solution half an hour before meals three times a day.

Other drugs

To increase the size of the endometrium and its successful maturation, drugs containing progesterone are used. In the second half of the therapeutic course, medications such as Duphaston and Utrozhestan are prescribed. These medications do not have a negative effect on a woman’s body and are completely harmless for pregnant women.

Folk remedies

Folk remedies can also effectively normalize the endometrium and its renewal during the menstrual cycle. At any home, you can prepare the necessary components and begin therapy.

The herb is popularly considered a natural hormone that helps not only for the growth of the mucous layer, but also activates ovulation processes. Therefore, this plant is widely used for pathologies of the reproductive systems in women.

Sage for growing the endometrium is taken orally in the form of a decoction. For this, 2 tsp. pour 0.5 l. boiling water After cooling, the solution should be filtered and consumed 100-130 g three times a day.

To carry out therapy you need to know your menstrual cycle, since you need to drink sage strictly with last day menstruation before ovulation. Although sage is a folk remedy, it cannot be used for prevention without a doctor’s prescription. The phytohormone has a strong effect and improper treatment can cause serious harm.

pumpkin juice

Pumpkin juice is best consumed freshly squeezed. Due to the lack of heat treatment and storage, it retains all the beneficial properties that help thicken the mucous layer of the uterus.

To achieve the effect you need to drink 200g of the product every day. This should be done constantly during the period of cell growth after menstruation. However, in another period pumpkin juice will be useful for normalizing reproductive functions.

Many women are already using pineapples for endometrial growth. It helps a lot and is pleasant and tasty to use.

Pineapple can be eaten without restrictions if not allergic manifestations. This needs to be done daily. It is also useful to include pineapple juice in your diet.

Blue clay

Blue clay is used to treat the problem and has pleasant conditions for the procedure. The product will help when wrapping the lower abdomen. To do this, the clay needs to be soaked in warm water and molded into a flat cake. It is applied to the lower abdomen and covered with film. After this, it is insulated with a terry towel. With such a compress, a woman lies down under a blanket for two hours. Afterwards, the body should be washed with warm water and lie down again in a warm place.

During therapy, it is better not to fall asleep, since the time is clearly defined by two hours. After this period, blue clay begins to act in the opposite way and release harmful substances back.

Raspberry leaves for the endometrium

Raspberry leaves are also considered a natural phytohormone. However, it does not have such strong action like sage. Raspberries are active and quite safe.

How to take: for endometriosis, you just need to steam raspberry leaves and drink throughout the day instead of the usual tea.

Borovaya uterus is one of the herbs that are popular in the treatment of female pathologies. It helps normalize hormonal levels and contains many useful microelements. Decoctions, alcohol tinctures and douching solutions are prepared from dried and crushed raw materials.

To prepare the decoction, you need to take 15g of raw materials and pour 150ml of boiling water. You need to infuse the solution for about an hour and take 1 tbsp. every 6 hours.

Red brush is one of the widely used plants that is used to eliminate gynecological diseases caused by a violation hormonal levels women. The red brush contains special components - phytohormones, which are an alternative to female sex hormones (estrogen and progesterone). Using decoctions based on of this plant, a representative of the fair sex will be able to stabilize normal level hormones, build up the mucous membrane (endometrium) in the reproductive organ and prevent the development of all kinds of diseases of the genitourinary system.

To grow the endometrium, pour one tablespoon of dry and crushed red brush into a glass of boiling water and leave this mixture for four hours. After this, drink the entire contents of the glass, repeating this procedure every 6 hours throughout the entire treatment course.

Other ways to help with extensions

People have long had the most popular methods in the treatment of infertility due to depletion of the uterus. The most popular were belly dancing, the use of leeches and various diets. With the combined use of all these tools, you can quickly achieve a positive result.

Leeches activate many processes in the body, cleanse the blood, inject beneficial microelements and help increase the thickness of the endometrium. The method operates on the principle of improving blood circulation in the pelvic organs and activating all processes.

Massages and acupuncture

Traditional Chinese medicine, based on acupuncture and massage, helps activate all functions of the reproductive system and helps increase the thickness of the mucosa. The needles are inserted into specific points on the body. These same points are also affected by massage.

Any failures often occur due to a lack of useful microelements in the body. Therefore, any course of therapy must be supplemented with vitamins.

The most important substances are vitamin E and C. These substances are responsible for tissue regeneration and therefore help to accelerate the growth of mucosis.

The best physical exercise to improve the condition of the uterus is belly dancing. But there are also physical complexes that improve blood circulation in the pelvic organs and help strengthen muscles.

Such gymnastics include:

• Exercise scissors while lying on your back, with your legs straight. Repeat from 8 to 15 times;
• Sitting on your heels, grab your hands behind your back. At first right hand goes over the shoulder, and the left one behind the back. Then change hands;
• Tilts. Feet shoulder width apart. Hands in front of you. Bend to your toes about 8-15 times;
• In the Turkish Sultan pose, place your hands on your legs and pull your stomach in. In this position, strain and relax the vaginal muscles. Repeat about 15 times;
• Exercise boat. Lying on your stomach, raise your arms and legs as high as possible. Stay in this position for 3-5 seconds.

It is especially important to perform small physical activities for women with a sedentary way of work and life.

No therapy is complete without a recommended diet. This allows you to establish the general background of the body and build all systems aimed at building up the endometrium. To do this, you need to eat foods that contain salicylates. These are active biological substances that help restore the genital organs and functions in the female body.

They are present in the following products:

• Beekeeping products;
• Dry red wine;
• Dried apricots, raisins, prunes and other dried fruits;
• Nuts and legumes;
• Vegetable fiber;
• Fruits, home and forest berries.

It is also important to include foods rich in fatty acids Omega. These substances are found in fatty fish and vegetable oils(olive, flaxseed, sprouted wheat).

How to grow the endometrium? Women with problems in this area are often interested in this issue. The endometrium is a necessary factor for a successful pregnancy. The endometrium thickens during the menstrual cycle, up to ovulation, in preparation for the implantation of the egg, and if fertilization does not occur, part of the layer falls off and is excreted from the body in the form of menstrual bleeding, the deeper layer begins to recover.

Endometrial functions, structure

The endometrium is the mucous membrane lining inner surface uterus. It consists of glandular and integumentary epithelium, stroma (connective tissue that develops during menstruation into mature cells that produce collagen, etc. necessary substances), ground substance and a large number of blood vessels. The main function of this mucous membrane is to create favorable conditions for attachment of the fertilized egg to the wall of the uterus and further development. As the egg grows, the endometrium gradually grows, transforming into the placenta - an organ that delivers oxygen and nutrients to the fetus. If fertilization has occurred, the fertilized egg attaches to the wall of the uterus, and the endometrium continues to develop and is not rejected - therefore, there is no menstrual bleeding during pregnancy.

What factors related to the endometrium affect pregnancy?

Thickness changes during the menstrual cycle, but this value also depends on factors such as age and the woman’s health. Changes in thickness and structure are regulated by the woman’s hormonal system, namely the hormone estradiol. There are standard indicators of what the thickness and structure of the endometrium should be at a certain age, and a certain phase of the cycle. These indicators ensure successful attachment of the fetus.

Endometrial indicators in different phases of the menstrual cycle:

• 5-7 days - 3-6 mm, homogeneous structure;
• 8-10 - 5-10 mm, thickening of the functional layer;
• 11-14 - 7-14 mm, ;
• 15-18 - 10-16 mm;
• 19-23 - 14 mm or more;
• 25-28 (on the eve of menstrual bleeding) - about 12 mm.

When pregnancy occurs, the endometrium thickens. Reaching 20 mm by 4-5 weeks, then transforms into the placenta. During menopause, hormonal changes in the body occur, in particular, the endometrium begins to atrophy, its thickness is about 3-4 mm.

Vitamins C and E, salicyl improve the process of endometrial maturation, so sufficient intake of them into a woman’s body is an important condition for treatment. To do this, it is recommended to include in the diet following products: citrus fruits, fresh vegetables, milk, raisins, grapes, prunes, ginger, dill. It is also possible to prescribe physiotherapeutic procedures and exercise. Physiotherapeutic procedures include: laser therapy, thermotherapy, treatment alternating current. In some cases, traditional medicine has an effective effect.

If it is insufficiently thick or hypoplastic, the fertilized egg cannot attach to the wall of the uterus, which causes infertility or miscarriage in women. In such cases, endometrial augmentation may be necessary. Causes of impaired maturation of the lining mucosa:

1. In case of disturbances in the hormonal system.
2. Congenital uterine hypoplasia is a discrepancy between the size of the uterus and the woman’s age.
3. The presence of inflammatory processes in the pelvic organs.
4. Insufficient blood supply to the uterus.
5. After curettage of the endometrium.
6. Curettage is a procedure that is prescribed for miscarriages, for the purpose of artificial termination of pregnancy, to obtain a sample of the endometrium (diagnostic purposes), in the presence of polyps in the uterus, endometrial hyperplasia (thickening) and other diseases.
7. Consequences of surgery.

Clinical manifestations of hypoplasia, diagnosis

Some signs may indicate hypoplasia:

1. Late onset of menstruation (over 16 years of age).
2. Menstrual bleeding disorders.
3. Underdevelopment of secondary sexual characteristics, insufficient hair growth (these signs indicate hormonal disorders), lack of orgasm.

Most often, when a woman cannot become pregnant, or the pregnancy is terminated, the risk of ectopic pregnancy is high. If it is possible to carry the fetus to term, then the pregnancy is difficult, with constant toxicosis and the threat of miscarriage, and childbirth is accompanied by complications (weak labor, insufficient opening of the uterine pharynx). Therefore, when planning pregnancy, endometrial examination is necessary. Treatment of problems associated with insufficient development of the endometrium depends on what caused this pathology.

To find out the details and obtain information on how to grow the endometrium, you should contact a qualified gynecologist; It may also be necessary to consult an endocrinologist.

Diagnostic procedures that are necessary to determine the causes of underdevelopment of the mucous membrane lining the uterus:

1. Gynecological examination.
2. Ultrasound of the pelvic organs.
3. Hormonal blood tests.
4. Biopsy of the uterus.

Extension methods

How to quickly grow the endometrium? After finding out the reasons for the underdeveloped endometrium, the doctor makes a decision on how to improve the endometrium: which ones should be prescribed medications, in what dosages, recommend physical exercises or physiotherapeutic procedures, etc. Pharmacological drugs prescribed for insufficient development of the endometrium:

1. Hormonal drugs based on estradiol (Divigel).
2. A medicine containing salicyl (Aspirin).
3. Hormonal drugs that activate estrogen production (Gormel).
4. Hormonal medicines containing synthesized progesterone, help improve the process of endometrial maturation (Duphaston, Utrozhestan).

1. Drinking sage decoction.
2. The use of tinctures of boron uterus.

Methods alternative medicine, which help improve blood circulation in the pelvic organs and improve the process of endometrial growth:

1. Acupressure.
2. Acupuncture is the impact on certain points of the body with special needles.
3. Hirudotherapy is a treatment method that involves applying medicinal leeches to certain areas of the body.

A woman who wants to get pregnant quickly is interested in how quickly the endometrium can grow. The answer depends on many factors: on the causes that caused the disorder, on the degree of development pathological process. The main thing is to contact a competent specialist and follow all the doctor’s recommendations.

And the woman herself - in vain. This problem is often encountered with polycystic ovary syndrome.

Causes of thin endometrium

The uterine mucosa is a hormone-dependent tissue, so the most common causes of its occurrence are hormonal.

Possible causes of thin endometrium:

• Hormonal. The growth of the endometrium before ovulation occurs primarily under the influence of estrogen. Estrogen provides thickness. And its secretory function is ensured. If the concentration of hormones is normal, but the receptors that are sensitive to them are damaged, then the thickness of the endometrium does not increase enough for implantation.
• Conditionally hormonal. Lack of vitamin D leads to disruption of steroid hormones.
• Vascular. Autoimmune diseases and pathologies of the blood coagulation system lead to disruption of the blood supply to the uterus, thereby preventing it from reaching the endometrium. required amount nutrients. Therefore, even if the endometrium is thin and grows poorly.
• Mechanical. Damage to the basal layer of the endometrium during medical manipulations– curettage, or as a result of infectious damage to the inner layer of the uterine mucosa, leads to the fact that the endometrium does not grow, since damage to the basal layer is the loss of stem cells, from which the functional layer grows.
• Congenital anomalies of the development of the uterus. For example, hypoplasia or aplasia of the uterus leads to the creation of a mechanical obstacle to the growth of the endometrium.

For thin endometrium, IVF is performed using technology. In this case (two days when the endometrium is receptive and is capable of implanting a blastocyst) is calculated.

Two programs allow you to grow the endometrium during IVF:

1. (hormone replacement therapy). In this case, estrogens are prescribed (tablets - Proginova, Estrafem or in gel form - Divigel, Estragel) at a dose of 4-8 mg per day. From the moment the endometrium reaches 8 mm and becomes three-layered, progesterone preparations (Utrozhestan, Proginova) are added for 5-6 days, depending on the one chosen for transfer. Progesterone and estrogen continue to be prescribed as support.
2. Transfer program in the presence of ovulation. At the beginning of the program, only vitamins can be prescribed: folic acid - for the prevention of defects, vitamin D. When the follicle reaches full maturity, one of the tactics is chosen. The first is the introduction of the ovulation trigger hCG. The second is clear monitoring of the onset of ovulation; ultrasound is done every day for this. As soon as ovulation has occurred, the reproductologist prescribes progesterone medications for 5-6 days and a transfer day is scheduled.

The effectiveness of endometrial augmentation of both programs is equivalent and is determined by the doctor individually.

During preparation, sometimes the endometrium remains thin, because hormonal factors are not the only reasons that prevent the endometrium from growing. In this case, it is necessary to carry out additional treatment prior to the transfer. The choice of therapy depends on the diagnosed disorders: antibiotic therapy to get rid of the infection, drugs to improve blood circulation (Curantil, Actovegin), surgical treatment.

The endometrium is the inner mucous layer of the uterus, equipped with blood vessels. It is responsible for creating favorable conditions for the implantation of a fertilized egg. If pregnancy does not occur, the function of the endometrium is to remove the unfertilized egg from the body along with menstrual blood. Any pathologies of the mucous layer (thickening, thinning) lead to failure in pregnancy. On average, its norm for unhindered implantation of the egg is 0.7 cm.

A thin layer of the endometrium is one of the common pathologies observed in women of reproductive age. Often this problem causes infertility.

Causes and signs of pathology

The thickness of the mucous layer can vary and depends on the day of the menstrual cycle. In the first days it does not exceed 0.5-0.9 cm, and a few days before the start of menstruation it reaches 1.3 cm. If the thickness is below 0.5 cm, we're talking about about hypoplasia (thinning) of the endometrium.

Why is the endometrium thinned?

Predisposing factors include:

• hormonal imbalance;
• endocrine diseases;
• congenital disorders in the blood supply to the uterus;
• chronic inflammatory processes in the genitals;
• Availability ;
• underdevelopment of the uterus;
• frequent use of funds emergency contraception(Postinor).

It is necessary to note the negative impact of surgical manipulations that were performed on the uterus. The consequences of curettage performed during abortions are especially dangerous. Some women with thin endometrium experience underdevelopment of the mammary glands, narrow pelvis, short stature, and later.

The disease does not have specific signs, so many women who are not planning a pregnancy may not even realize there is a problem. Typically, the diagnosis of hypoplasia is established in the process of determining the reason why pregnancy either does not occur or is terminated in the early stages.

Thinning may be indicated by scanty periods. You should also be wary of painful periods, the presence large clots in the blood, discharge in the middle of the menstrual cycle. Sometimes in reproductive age may arise uterine bleeding. The listed symptoms should be the basis for a visit to the gynecologist.

The likelihood of pregnancy with this pathology

In most cases, thinning of the uterine mucosa worries women who are planning to conceive or those who have had a long-awaited pregnancy after previous failures. What to do if the endometrium is thin and how does this affect the development of the fetus?

First of all, women are reduced in their ability to become pregnant naturally, since the thin mucous layer of the uterus prevents the implantation of the fertilized egg.

Is it possible to get pregnant with a thin endometrium?

Medicine knows of cases where conception occurred even with a thickness of 0.4 cm. But if pregnancy does occur, the risk of its interruption in the early stages, the appearance of bleeding, and subsequent weakness increases. labor activity and other complications during childbirth.

After conception has occurred, the endometrium continues to grow. In the first trimester, its thickness reaches 2 cm or more. Often, it is its significant increase that allows the doctor to determine pregnancy on an ultrasound, since the fertilized egg itself may not yet be noticeable. In the early stages of pregnancy, a thin endometrium requires increased attention from doctors and immediate treatment, since it can occur at any time.

Separate mention should be made of the IVF procedure when diagnosing thin endometrium. This procedure is extremely undesirable for such a pathology, since the chances of the embryo being successfully implanted in the uterus are extremely low. The probability of pregnancy with a thickness below 0.7 cm is no more than 15%. Therefore, the patient is advised to postpone the procedure and take appropriate measures.

Diagnosis and treatment

After studying common symptoms The patient is prescribed:

• Ultrasound of the uterus, which is performed several times at different phases of the cycle;
• general urine and blood tests;
• responsible for the onset and successful course of pregnancy;
• Ultrasound of the pelvic organs;
• taking samples of uterine tissue for histological examination;
• biopsy of the uterine body.

These studies make it possible not only to establish the fact of endometrial thinning, but also to determine the causes of the pathology.

Treatment for thin endometrium depends on the reasons that caused it. In most cases, this is an imbalance of the hormonal system. Therefore, pregnant women with this pathology need hormone therapy drugs containing progesterone. Treatment regimens, dosage, and duration of therapy are carried out exclusively by the attending physician on an individual basis.

If hypoplasia is caused by chronic inflammatory diseases of the genital organs, drug therapy should be aimed at eliminating the source of inflammation. In some cases, there may be indications for surgical treatment. It consists of removing the inner layer and further hormone therapy. These methods help to renew the mucous layer of the uterus and normalize its thickness.

For circulatory disorders, treatment with conservative methods, among them: massage, physiotherapy, hirudotherapy, acupuncture, therapeutic exercises.

Drug therapy

To provide normal pregnancy, it is necessary to increase the thin endometrium. The patient may be prescribed combination medications that normalize hormone levels, a course of treatment with estradiol, and medications containing progesterone (Utrozhestan, Duphaston).

• Duphaston

Although this drug is an artificially synthesized hormone, it successfully performs all the tasks that are inherent in progesterone. The product effectively prepares the uterus for the upcoming pregnancy, relieves it muscle tone, prevents epithelial detachment. The usual regimen for taking the drug is from the 11th to the 25th day of the cycle, but you cannot make a decision about taking it yourself. Admission is carried out only on the recommendation of a doctor.

• Melsmon

The placental drug Melsmon contains placenta taken from women whose births occurred without complications. It is widely used in cosmetology, but is also used to normalize the menstrual cycle and relieve syndrome chronic fatigue, eliminating the symptoms of inflammation.

The drug is not used during pregnancy, in case of disturbances in the functioning of the endocrine system, renal or liver failure, high blood pressure.

• Actovegin

Actovegin is intended to maximize blood circulation in the genital area. Increasing blood circulation is the key to successfully overcoming hypoplasia. The standard dosage regimen involves taking 1-2 tablets three times a day. Typically, the course of treatment lasts 4-6 weeks, determined by the doctor individually. The drug can also be taken during pregnancy, starting from the 16th week, when the formation of the placenta ends.

• Gormel

This product belongs to homeopathic medicines. It activates the synthesis of estrogen. It consists of natural ingredients And alcohol tincture. The regimen for taking the drug is as follows: 10 drops are mixed with half a glass of water and the mixture is drunk half an hour to an hour before meals three times a day. The duration of treatment can vary from one to three times a month, depending on the results obtained.

Since the drug contains alcohol, it should not be taken during pregnancy. Contraindications also include brain injuries and diseases, renal failure. The drug should be completed before the stage of active pregnancy planning.

In case of thin endometrium, it should be carried out only as prescribed by a doctor and under his strict supervision. The use of the drug Clostilbegit can lead to even greater thinning, so it is usually taken simultaneously with the estrogen-containing drug Proginova.

Physiotherapy

Physiotherapy procedures indicated for thin endometrium have a number of advantages. They provide gentle therapeutic effect, do not call side effects, reduce drug dependence. They are usually prescribed as part of complex therapy.

The treatment uses magnetic therapy, ultrasound, ultraviolet light, massage, mud baths. The most favorable period for treatment is the first days after the end of menstruation. You can enhance the effect of physiotherapy by following the rules of nutrition, taking walks in the fresh air, and regularly doing therapeutic exercises.

Treatment with folk remedies

In addition to the use of medications, you can increase the endometrium using folk remedies.

1. Sage tea. A teaspoon of crushed plant is poured into 200 ml of boiling water and left to infuse for several hours. The resulting infusion is taken for four months in the first half of the menstrual cycle.
2. Infusion of boron uterus. 2-3 teaspoons of the plant or ready-made sachets purchased at the pharmacy are poured with a glass of boiling water. After infusion for a quarter of an hour, you can take it daily.
3. Pineapples and pumpkin, which are allowed to be eaten in unlimited quantities, provided that you are not allergic to these products. You can drink pineapple and pumpkin juices.
4. Raspberry leaf tea. The prepared leaves are poured with boiling water and the tea is drunk in small quantities several times a day.
5. A combined decoction prepared from elderberry inflorescences, yarrow herbs, mint, chamomile, nettle, and medicinal cap. A mixture of components taken in equal proportions is poured into 1 liter of boiling water, infused for an hour and taken half an hour before meals 3-4 times a day.

Regular treatment with folk remedies gives positive results within a few months. However, the use of any traditional medicine must be supported by drug therapy and carried out in consultation with the attending physician. It should be noted that some herbs have contraindications for use if the patient has other diseases.

Diet

The basis successful treatment– proper nutrition. It must include foods rich in vitamins A and E, as well as foods with high levels of salicylates. You should include in your diet fatty varieties fish, vegetables (tomatoes, bell peppers, spinach, cucumbers, beans, cabbage), fruits and berries (grapes, apples, currants, raspberries), dried fruits, honey, red wine.

A variety of spices are useful, such as paprika, thyme, cinnamon, curry. At the same time, a woman needs to limit her intake of fatty and sweet foods, as well as fast food, strong coffee and tea.

Plays an important role in growing the endometrium active image life. It is useful to play sports and dance, visit the pool. This stimulates active blood circulation, which has a positive effect on his condition.

Endometrial hyperplasia- This is the growth of the inner mucous membrane of the uterus. Doctors believe that this is not a disease, but a special condition - a malfunction of an organ that is caused by hormonal imbalances. Its manifestations: prolonged delay of menstruation, after which heavy bleeding occurs, bloody issues in the middle of the cycle. But often hyperplasia does not cause any symptoms and is discovered accidentally during an ultrasound.

The main danger is that although endometrial hypertrophy is a benign formation, it can degenerate into a malignant cancerous tumor.

Is there a high risk of getting sick?

What happens in the body?

If a failure occurs in this well-functioning system, the cells of the inner layer of the uterus divide very actively. But they don’t come out on time because there is no menstruation. As a result, the endometrium becomes thicker. Changes in it can be varied. In some women, only certain areas of the mucous membrane enlarge: outgrowths and polyps form. In others, the endometrium thickens evenly.

But endometrial growth cannot last long. After a few months, the uterus still sheds it. Then heavy bleeding occurs. If the cause of endometrial hyperplasia is not eliminated, then everything repeats again and again.

Anatomy of the uterus

Uterus - represents an empty muscular organ. It consists of smooth muscles that we cannot consciously control. Its walls are thick, dense and elastic. This allows the uterus to stretch during pregnancy and reliably protect the fetus. The internal space of the uterus is small, it can hold 5-7 ml of fluid.

The organ itself looks like an inverted triangle, flattened in front and behind. Its base faces upward and is located above the place where the fallopian tubes enter. The lower part narrows and passes into the isthmus, and below into the cervix. This area is denser and contains more connective tissue. The cervical canal runs inside the cervix, which opens from above into the uterine cavity and from below into the vagina. During childbirth, the baby leaves the uterus this way.

The uterus is located in lower section abdominal cavity. It is located between bladder, which lies in front of her, and the rectum, which is behind. The uterus is small: height 8 cm, width up to 4 cm, thickness 2 cm. For nulliparous women, its weight is about 40 g, and for those who have already given birth to a child, it weighs 2 times more.
The uterus is attached to the walls of the pelvis by several ligaments. They hold the organ in place and prevent it from descending.

Structure of the uterus

1. Outer serous membrane - perimeter. It is formed from a layer of peritoneum that lines abdominal cavity and covers the internal organs. In some places the perimeter is tightly fused with the muscle layer, while in other areas it is loosely attached. This allows the uterus to stretch better. On the anterior surface and sides of the cervix lies fatty tissue.
2. Middle muscle layer - myometrium. It is the thickest and consists of fibers of non-striated smooth muscles that intertwine in different directions. There are also elastic fibers and connective tissue fibers. This provides additional protection to the fetus. The myometrium has three layers
   • Outer – longitudinal layer muscle fibers. Fuses with the serous membrane.
   • Middle – circular or vascular layer. The muscles here look like rings; in their thickness there are many vessels, mainly veins.
   • Inner – longitudinal layer. It is the thinnest and is located under the mucous layer.
3. Mucosa - endometrium. Consists of columnar epithelium that lines the inner surface of the uterus. It also includes simple tubular glands and a thin layer of connective tissue.

The structure of the endometrium

The endometrium consists of two layers: functional and basal.

On the surface there is a layer called functional. He is very sensitive to sex hormones, which control his changes. After menstruation, the thickness of this layer is 1 mm. By the end of the cycle, it increases to 6-8 mm and flakes off during the next menstruation.

Functional layer performs many functions. Its surface is flat, smooth, without folds. Cover it up ciliated cells. Each of them has up to 500 thin eyelashes. Together they vibrate and create waves that help the fertilized egg move.

There are also simple tubular glands, which secrete a special mucous secretion. This substance provides normal work the uterus and prevents its inner walls from sticking together.

Endometrial stroma- a special type of connective cells arranged in a grid. Under the influence of hormones, they change and perform different functions: provide nutrition, protect against damage, produce collagen and participate in the rejection of the top layer.

Vessels of the superficial layer V different phases cycles change greatly. At first they straighten, and closer to menstruation they twist in a spiral. When pregnancy occurs, it is these vessels that form the placenta, which brings nutrients to the embryo.

Under surface layer located basal . The main function is to restore the endometrium after “critical” days. It does not respond as sensitively to hormonal changes and changes little throughout the cycle.
This layer contains “vesicle cells”, from which the ciliated cells of the superficial layer are subsequently formed. The stroma of the basal layer is dense and consists of connective tissue cells.

What affects the growth of the endometrium?

• Estrogens are normally produced in the first half of the menstrual cycle - the first 2 weeks. They are responsible for the restoration of the endometrium after menstruation and its growth (proliferation).
• Progesterone appears in the second half of the cycle in the third week. It stops the growth of the mucous membrane, starts the secretion phase - prepares the ground for the attachment of the embryo.

If there is too much estrogen, then growth occurs constantly. And due to progesterone deficiency, the growth of endometrial cells does not stop.

How does menstruation and endometrial shedding occur?

At the end of the cycle, if pregnancy has not occurred, the corpus luteum of the ovary abruptly stops producing hormones. This causes spasm of the uterine vessels, its cells experience oxygen starvation and begin to die off.

The walls of blood vessels become more permeable. Through them, leukocytes and the liquid part of the blood emerge, which permeates the endometrium. After a period of narrowing, the arterioles expand sharply: the vessels rupture and bleeding occurs.

The stroma contains granular cells. Before menstruation, they secrete special substances that peel off the functional layer. It comes out with the blood.

Special enzymes, which are formed during the breakdown of the mucous membrane, prevent blood from clotting.

What is endometrial hypertrophy

Now let's figure out what the term hypertrophy means. This is an increase in the volume and mass of the layers that make up the endometrium. This process begins from the first day after menstruation and ends before the next critical days - this is normal. physiological hypertrophy.

If for some reason your period does not come, then the endometrium continues to grow. Now not only the size of the cells increases, but also their number. This is already called hyperplasia. This condition goes beyond the norm and requires treatment.

Mechanism of development of hyperplasia

These processes are regulated by ovarian hormones. If a woman does not have enough progesterone, then ovulation and then menstruation do not occur on time. In this case, the endometrium thickens due to increased cell division, which should not normally occur.

An excess of estrogen hormones in the blood leads to the growth of glands that are located in the thickness of the endometrium. A high level gestagens causes increased division of the stroma.

Reasons for the development of hyperplasia

Metabolic disorders. The cause may be disorders of fat and carbohydrate metabolism, obesity. The fact is that adipose tissue is able to produce estrogens. Some general diseases also increase the risk of hyperplasia. This diabetes, chronic diseases liver, hypertension.

Diseases of the endocrine glands: adrenal glands, pancreas and thyroid cause malfunction of the ovaries or the endometrium itself. This may lead to enhanced growth cells.

Age-related changes in the genitals cause endometrial hyperplasia. He becomes more sensitive to the action of hormones. This pathology occurs in 60% of women during menopause and after it. She often calls heavy bleeding and the appearance of tumors. There is also a high risk of developing the disease in teenage girls during puberty.

Inflammation of the uterus and other genital organs cause hyperplasia. It can be a consequence of sexually transmitted infections, intrauterine contraceptives (spirals). Inflammation causes many immune cells to accumulate in the tissues of the uterus. They cause endometrial cells to actively divide.

Curettage and frequent abortions, and birth defects development of the uterus are also factors that cause the growth of the endometrium. They cause endometrial receptors to become insensitive to the action of progesterone. Therefore, cells continue to multiply even if hormones are normal.

Disruption immune system . There is a version that the cause of endometrial hyperplasia may be incorrect operation immune cells. They mistakenly attack the lining of the uterus, causing its cells to divide incorrectly.

Genetics. There is also a hereditary predisposition to hyperplasia. If the mother had the disease, then her daughters may also have such problems.

Types of endometrial hypertrophy

Glandular form
Refers to benign changes and is considered the easiest. This means that the likelihood of developing cancerous tumors in this case it is small, only 2-6%. Gland cells are actively dividing, and the endometrium becomes thicker. The glands are located unevenly, but in groups. They may be pressed closely together. There are no stromal cells between them. Tubular glands change from straight to tortuous and expand. But at the same time, their contents are freely allocated.

Glandular-cystic form
If the cells at the mouth of the gland grow strongly, they block the outflow of mucus. It takes the form of a cyst - a bubble filled with fluid. These changes occur under the influence of estrogen hormones.

Cystic form
This form has much in common with glandular cystic. The glandular cells grow greatly and the glands themselves increase in size. They become like a bubble. But unlike previous variants of the development of the disease, inner part The gland is lined with normal epithelium. Such cysts can develop into cancerous tumors.

Focal form
The proliferation of endometrial cells does not occur uniformly, but in separate foci. These areas of the mucosa are more sensitive to the action of hormones, so the cells here divide more actively. Elevations form on the endometrium with altered glands and formations similar to cysts. If cell reproduction begins in a polyp, then it greatly increases in size. The diameter of the lesions can range from several millimeters to several centimeters. There is a risk of cancer forming at the site of the outbreak. If changes occur evenly over the entire surface of the endometrium, then this form is called diffuse.

Atypical form (adenomatosis)
It is considered the most dangerous of all variants of the disease. Endometrial hyperplasia with atypia most often leads to cancer. According to some data, the risk of degeneration is more than 50%. Therefore, in this case, it is recommended to remove the uterus. Changes take place not only in the functional, but also in the basal layer. The cells of the stroma and glands are actively dividing and rebuilding. Mutations often occur in them. They become atypical. Cells change their structure and the structure of the nucleus.

The choice of treatment depends on the form of the disease. If in the glandular form you can get by with taking hormones, then in the atypical form during menopause it is necessary to remove the uterus.

Symptoms and signs of endometrial hyperplasia

Symptoms of endometrial hyperplasia.

1. Menstrual disorders. This is the most common sign of the disease. The cycle gets confused, menstruation becomes irregular. Bloody discharge is often heterogeneous. Blood clots and particles of overgrown mucous membranes that have peeled off may appear.
2. Painful periods (algomenorrhea). This phenomenon is quite common in 70% of women. But if earlier menstruation was painless, and after a certain period each cycle there are discomfort- This is a sign of violations. Pain during menstruation is caused by vasospasm and increased pressure inside the uterus. Especially when a large amount of the functional layer peels off.
3. Bloody discharge before and after menstruation occur with polyps. With this form of the disease, the walls of the blood vessels become brittle, and the liquid component of the blood escapes through them.
4. Bloody spotting in the middle of the menstrual cycle. A decrease in the amount of estrogen leads to detachment of the mucosa. But it is not completely rejected, as during menstruation, but in small sections. The discharge is not as heavy as during menstruation. They occur after physical activity or sex.
5. Delayed menstruation, which ends in severe bleeding . Menstruation does not start on time, and a large amount of estrogen causes endometrial cells to grow further. But, in the end, there comes a time when the amount of hormones drops, and the uterus is still freed from the enlarged mucosa. And then the entire functional layer, which has already reached a thickness of 2-3 cm, is released out along with big amount blood.
6. Infertility. Hormonal changes, which occur with endometrial hyperplasia, interfere with ovulation. Therefore, there is very little chance of fertilization of the egg. If this does happen, then the egg simply cannot take root in the uterus. After all, the affected endometrium is poor soil and cannot form a placenta.
7. Long and heavy bleeding during menstruation regular cycle . In this case, bleeding continues for more than 7 days. This is due to the fact that special enzymes prevent blood from clotting.

Diagnosis of endometrial hyperplasia

Treatment of endometrial hyperplasia

Drug treatment

Combined oral contraceptives

Synthetic analogues of progesterone

Since endometrial hyperplasia occurs due to a lack of progesterone, its use can save a woman from this disease. An artificially created sex hormone acts in the same way as the one produced in the body. It is able to normalize the menstrual cycle.

The use of gestagens helps women of any age and with any form of endometrial hyperplasia. However, during use, spotting may occur between periods.

Treatment lasts 3-6 months. The best results are obtained with the drugs Duphaston and Norkolut.

Gonadotropin releasing hormone antagonists (AGnRH)

These modern drugs allow you to reduce the production of female sex hormones estrogen, which causes endometrial growth. After using these agents, cell division slows down and the thickness of the mucosa decreases. This process is called endometrial atrophy. Thanks to AGnRH, infertility and hysterectomy can be avoided.

The drugs are easy to dose and convenient to use. They can be administered as an injection once a month (Goselerin, Leuprorelin). AGnRH is also available in the form of a nasal spray (Buselerin or Nafarelin). They help so many women.

During the first two weeks, a woman may feel a slight deterioration in her condition. This happens because estrogen levels rise during this period. But then their production stops and improvement occurs, menstrual bleeding becomes regular and painless. Duration of treatment is 4-10 weeks.

Treatment with surgical methods

This is one of the main methods of treatment and diagnosis of endometrial hyperplasia. The procedure lasts about 20 minutes and is performed under intravenous anesthesia. The doctor uses a special surgical instrument - a curette - to remove the superficial functional layer of the endometrium. Essentially, the doctor does in 20 minutes what happens during menstruation in 5 days.

Cryodestruction

This is the “freezing out” of hyperplastic areas of the endometrium using low temperatures. Cold causes cell death (necrosis). Then the area destroyed by the cold is torn away and comes out.

Laser ablation or cauterization

Cauterization with a laser or electrosurgical instrument heated to high temperatures. Areas of hyperplasia are destroyed and then come out of the uterus on their own. After such a procedure, the mucous membrane is restored naturally, as after menstruation.

Removal of the uterus or hysterectomy

Complete removal uteri are carried out only in case of complex atypical forms. It is often prescribed to women during menopause, when the risk of developing cancer increases. If there are no changes in the ovaries, then they are left in place.
Complete removal of the uterus, fallopian tubes and ovaries is carried out for adenomatosis, if a woman has completed menopause. And also in the case when cancer cells are detected.

In most cases, after any operation, hormonal medications are prescribed. They can improve a woman’s condition and prevent re-growth of the endometrium.

What is endometrial hypertrophy during menopause?

This condition is observed in almost 70% of women at this age. The changes occur because hormonal changes occur during menopause and estrogen levels increase. In addition, after 40 years of age, the likelihood of developing cancer increases. Therefore, a woman needs to be especially attentive to her health.

The following factors increase the risk of developing endometrial hyperplasia:

• diabetes
• high blood pressure
• early start menopause
• excess weight
• chronic liver diseases
• uterine fibroids, ovarian cysts, mastopathy
• hereditary tendency

The first stage is ultrasound. If the thickness of the endometrium is 6-7 mm, then a repeat examination is prescribed after 3-6 months. If the thickness is more than 8 mm, treatment is necessary, and if it is more than 10 mm, then separate curettage.

Treatment of endometrial hyperplasia in menopause

1. Treatment with hormones. For many women, it gives excellent results and allows you to do without surgery. The drugs Megestrol acetate and Medroxyprogesterone are taken for a long time, 3-6 months. Ultrasounds are performed periodically to determine whether there is any improvement and, if necessary, adjust the dose of medications.
2. Surgery:
   • Laser cauterization (ablation). Carried out if the endometrium grows in patches or in the form of polyps
   • Curettage using a surgical curette (curettage). The functional layer of the endometrium is removed.
   • Removal of the uterus (sometimes with appendages). Prescribed if a tendency to form a cancerous tumor has been identified.
3. Combined treatment . During menopause, it is prescribed first hormonal treatment, while areas of hypertrophy decrease. This makes the operation less traumatic.

Is curettage necessary for endometrial hypertrophy?

Before curettage, a number of tests are prescribed:

• general blood analysis;
• blood test for coagulation (coagulogram);
• heart cardiogram;
• blood tests for hepatitis, syphilis, HIV,
• swab for vaginal cleanliness.

Why is curettage done?

For diagnosis, after scraping, tissue particles are sent to the laboratory. There they are carefully studied under a microscope. They determine whether there are cysts, whether the structure of the glands is disrupted, and whether the cells are prone to mutations that lead to cancer. After such a study, the necessary medications are prescribed. This is the most accurate diagnostic method for endometrial hyperplasia. Since during ultrasound or endoscopy the doctor may not notice any abnormalities.

Scraping with therapeutic purpose allows you to quickly get rid of polyps and hyperplastic epithelium. This is the fastest and most effective method of treatment. This procedure is especially necessary for women who have not been helped by hormones.

Curettage for endometrial hyperplasia can be carried out under vision or hysteroscope control. This is a thin tube with a small camera attached to the end. Such a device allows you to monitor the process on the screen and evaluate the quality of work so as not to miss anything.

Curettage is performed with a curette. This surgical instrument, similar to a small spoon with a pointed edge on a long thin handle.

Curettage is considered minor gynecological surgery. It is done very often, and most women have gone through it. The procedure lasts less than 20 minutes and is done under intravenous anesthesia. Therefore, the woman does not feel pain. She can return home that same day.

After curettage, antibiotics are usually prescribed to prevent inflammation. After the analysis is done, the doctor may prescribe hormonal medications to prevent recurrence of endometrial hyperplasia.

How to treat endometrial hypertrophy with folk remedies?

Universal complex of celandine and vegetable juice

1st month. Every day you need to drink 100 g of freshly squeezed beet and carrot juice. Beet juice It is better to drink in the morning on an empty stomach, and carrots before lunch. In addition, you should take 1 tbsp twice a day. flax seed oil before meals.
Once every two weeks it is necessary to douche with an infusion of celandine. To prepare one serving of infusion, you need to pour 50 g of fresh celandine herb into 2 liters of boiling water. Let it brew for 12 hours. Before douching, warm the infusion to body temperature.

2nd month. Add 150 ml of aloe tincture to daily juice therapy. To prepare it, you need to take 400 g of juice from aloe leaves and mix it with the same amount of honey. Pour the resulting mixture into 0.7 liters of Cahors and let it brew for 15 days.
Also in the second month, an infusion of boron uterus (motherland) is added. 2 tbsp. dry herbs pour 1 liter of boiling water. Leave for 3 hours.
Douching continues without changes.

3rd month. Continue to take juices, flaxseed oil, aloe and infusion of boron uterus. Stop the douching procedure.

4th month . Treatment begins with a week's break. Subsequently, over the course of a month, treatment is reduced to taking oil from flaxseeds and tinctures of boron uterus.
This complex remedy strengthens the immune system, improves the condition of the genital organs and urinary system. The production of hormones and the condition of the endometrium are normalized.

Stinging nettle

Nettle contains unique phytohormones, similar to those of women. Therefore, this herb in all its forms has beneficial influence on women's health.

Alcohol tincture of nettle - ideal for restoring the full functioning of the hormonal system in women. To prepare the tincture, you need to pour 100 g of crushed nettle leaves into 400 g of medical alcohol. Let it sit in a dark place for 10 days. Strain and take 1 tsp. with a little water. Use in the morning and evening after meals.

Within a week there should be an improvement in your general condition. Gradually, the body's hormonal processes stabilize. Usually it is necessary to drink the tincture for 1 month.

Nettle decoction. To prepare the decoction, take young nettle leaves and pour boiling water at the rate: per 100 g of leaves - 1 liter of water. Take 100 g of decoction 5 times a day on an empty stomach.

Herbal decoction

Most effective folk remedy considered from endometrial hyperplasia herbal tea. Its composition includes in equal proportions: calamus, knotweed, cinquefoil root, nettle leaves, as well as ½ portion each of serpentine and shepherd's purse.

To prepare the decoction, you need to take 4 tbsp. collecting herbs. Pour into an enamel pan and pour 1 liter of boiling water. Boil for 3-5 minutes. After this, wrap the dishes in a towel and leave for 3 hours.

Drink the decoction once a day, 200 ml in small sips. The course of treatment lasts 2 months. Use the collection for one month, then take a break for a week. And again a month of treatment. The first effects will be noticeable within 2 weeks. If the effect is not noticeable after completion of treatment, the course can be repeated after a two-week break.

Is pregnancy possible with endometrial hypertrophy?

Let me explain. Endometrial hyperplasia – complex disease. This is not only a thickening of the uterine mucosa, but also serious deviations in the production of hormones. All glands internal secretion, which secrete hormones, are interconnected. Disturbances simultaneously occur in the hypothalamus, pituitary gland and ovaries. This causes an excess of estrogen and a lack of progesterone. As a result, the woman does not ovulate - the egg does not enter the uterus from the follicle. This means fertilization is also impossible.

Also, for pregnancy to occur, it is necessary that the fertilized egg penetrates the lining of the uterus. But with hyperplasia, the endometrium is so changed that the egg simply cannot do this.
A healthy endometrium and normal production of female sex hormones are a necessary condition women's health and the onset of pregnancy. Therefore, it is necessary to regularly visit a gynecologist once a year. Women over 45 years old are recommended to do this every six months. Such preventive examinations will help identify any changes in the early stages and easily get rid of them.